nfkb1 (Danio rerio)
Rel

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00554 (RHD_DNA_bind) IPR011539 ENSDARG00000105261 T317109_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Is expressed in retina. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); common variable immunodeficiency; melanoma; prostate cancer; and tropical spastic paraparesis. Orthologous to several human genes including BICDL1 (BICD family like cargo adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFKB1
M03448_2.00 		Homo sapiens
MGGGGAWTCCCCT
AGGGGAWTCCCCK		 SELEX
Jolma et al.(2013)
NFKB1_1 		0.734 0.734
NFKB1
M05887_2.00 		Homo sapiens
NGGKRNTYYCCCN
NGGGRRANYMCCN		 SMiLE-seq
Isakova et al.(2017)
NFKB1 		0.734 0.734
NFKB1
M09348_2.00 		Homo sapiens
HYTTCCCY
RGGGAARD		 Misc
Kulakovskiy et al.(2013)
NFKB1_HUMAN.H11MO.0.A 		0.734 0.734
NFKB1
M11228_2.00 		Homo sapiens
GGGGATYCCC
GGGRATCCCC		 Transfac
Matys et al.(2006)
V$NFKAPPAB50_01 		0.734 0.734
NFKB1
M11229_2.00 		Homo sapiens
NGGGAHTYYCCM
KGGRRADTCCCN		 Transfac
Matys et al.(2006)
V$NFKB_C 		0.734 0.734
NFKB1
M11230_2.00 		Homo sapiens
DKGGGAMTTYCCNN
NNGGRAAKTCCCMH		 Transfac
Matys et al.(2006)
V$NFKB_Q6 		0.734 0.734
NFKB1
M11231_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$P50_Q6 		0.734 0.734
Nfkb1
M09358_2.00 		Mus musculus
GGGRNTTYCCC
GGGRAANYCCC		 Misc
Kulakovskiy et al.(2013)
NFKB1_MOUSE.H11MO.0.A 		0.728 0.728
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000131701 Rel 49 247
ENSDARP00000135800 Rel 55 253

Links

Other Rel family TFs
Other Danio rerio TFs

Invalid Input OrderBy

65 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action