ISCW023333 (Ixodes scapularis)
Runt

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00853 (Runt) IPR013524 ISCW023333 T319583_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
RUNX3
M03464_2.00 		Homo sapiens
HRACCGCAAACCRCAN
NTGYGGTTTGCGGTYD		 SELEX
Jolma et al.(2013)
RUNX3_1 		0.798 0.798
RUNX3
M03465_2.00 		Homo sapiens
WAACCRCARN
NYTGYGGTTW		 SELEX
Jolma et al.(2013)
RUNX3_2 		0.798 0.798
RUNX3
M03466_2.00 		Homo sapiens
HDACCRCADWAACCRCRN
NYGYGGTTWHTGYGGTHD		 SELEX
Jolma et al.(2013)
RUNX3_3 		0.798 0.798
RUNX3
M03467_2.00 		Homo sapiens
HRACCRCAAH
DTTGYGGTYD		 SELEX
Jolma et al.(2013)
RUNX3_4 		0.798 0.798
RUNX3
M02751_2.00 		Homo sapiens
WACCRCAM
KTGYGGTW		 SELEX
Jolma et al.(2010)
RUNX3_monomer 		0.798 0.798
RUNX3
M05731_2.00 		Homo sapiens
YWAACCGCAAAAACCGCARV
BYTGCGGTTTTTGCGGTTWR		 SELEX
Yin et al.(2017)
RUNX3_FL_HT-SELEX 		0.798 0.798
RUNX3
M09369_2.00 		Homo sapiens
HAACCACARN
NYTGTGGTTD		 Misc
Kulakovskiy et al.(2013)
RUNX3_HUMAN.H11MO.0.A 		0.798 0.798
Runx3
M09374_2.00 		Mus musculus
NHRACCACARVN
NBYTGTGGTYDN		 Misc
Kulakovskiy et al.(2013)
RUNX3_MOUSE.H11MO.0.A 		0.798 0.798
RUNX3
M11252_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML2_Q3_01 		0.798 0.798
RUNX3
M11253_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML2_Q3 		0.798 0.798
RUNX3
M11254_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML2_Q4 		0.798 0.798
RUNX3
M05732_2.00 		Homo sapiens
HWAACCACRAAAACCACRARN
NYTYGTGGTTTTYGTGGTTWD		 SELEX
Yin et al.(2017)
RUNX3_FL_Methyl-HT-SELEX 		0.798 0.798
Runx1
M08163_2.00 		Mus musculus
HRRCCACARVN
NBYTGTGGYYD		 ChIP-seq
Mathelier et al.(2014)
MA0002.2 		0.775 0.775
RUNX1
M09371_2.00 		Homo sapiens
NWAACCACARV
BYTGTGGTTWN		 Misc
Kulakovskiy et al.(2013)
RUNX1_HUMAN.H11MO.0.A 		0.775 0.775
Runx1
M09372_2.00 		Mus musculus
VWRACCACARVV
BBYTGTGGTYWB		 Misc
Kulakovskiy et al.(2013)
RUNX1_MOUSE.H11MO.0.A 		0.775 0.775
RUNX1
M09632_2.00 		Homo sapiens
HAACCACADV
BHTGTGGTTD		 Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE29180 		0.775 0.775
RUNX1
M09631_2.00 		Homo sapiens
VCCACWTCCTBY
RVAGGAWGTGGB		 Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE17954 		0.775 0.775
Runx1
M09633_2.00 		Mus musculus
NWAACCACAR
YTGTGGTTWN		 Misc
Heinz et al.(2010)
HPC7-Runx1_GSE22178 		0.775 0.775
RUNX1
M11258_2.00 		Homo sapiens
ACCRCA
TGYGGT		 Transfac
Matys et al.(2006)
V$AML1_01 		0.775 0.775
RUNX1
M11259_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q4_01 		0.775 0.775
RUNX1
M11260_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q4_02 		0.775 0.775
RUNX1
M11261_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q4 		0.775 0.775
RUNX1
M11262_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q5 		0.775 0.775
RUNX1
M11263_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML1_Q6 		0.775 0.775
Runx2
M01307_2.00 		Mus musculus
NHDACCRCAN
NTGYGGTHDN		 PBM
Lambert et al.(2019)
pTH9764 		0.764 0.764
RUNX2
M03468_2.00 		Homo sapiens
HRACCGCAAACCRCRD
HYGYGGTTTGCGGTYD		 SELEX
Jolma et al.(2013)
RUNX2_1 		0.764 0.764
RUNX2
M03469_2.00 		Homo sapiens
HRACCRCADWWACCRCAD
HTGYGGTWWHTGYGGTYD		 SELEX
Jolma et al.(2013)
RUNX2_2 		0.764 0.764
RUNX2
M03470_2.00 		Homo sapiens
WAACCRCAR
YTGYGGTTW		 SELEX
Jolma et al.(2013)
RUNX2_3 		0.764 0.764
RUNX2
M05733_2.00 		Homo sapiens
NHRACCRCADWAACCRCAVN
NBTGYGGTTWHTGYGGTYDN		 SELEX
Yin et al.(2017)
RUNX2_eDBD_HT-SELEX 		0.764 0.764
RUNX2
M09370_2.00 		Homo sapiens
MMHAACCACAVVMH
DKBBTGTGGTTDKK		 Misc
Kulakovskiy et al.(2013)
RUNX2_HUMAN.H11MO.0.A 		0.764 0.764
Runx2
M09373_2.00 		Mus musculus
VWRACCACARVV
BBYTGTGGTYWB		 Misc
Kulakovskiy et al.(2013)
RUNX2_MOUSE.H11MO.0.A 		0.764 0.764
RUNX2
M09630_2.00 		Homo sapiens
NHVACCACANNN
NNNTGTGGTBDN		 Misc
Heinz et al.(2010)
PCa-RUNX2_GSE33889 		0.764 0.764
RUNX2
M11255_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML3_Q3 		0.764 0.764
RUNX2
M11256_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$AML3_Q6 		0.764 0.764
RUNX2
M11257_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$OSF2_Q6 		0.764 0.764
RUNX2
M05734_2.00 		Homo sapiens
NWAACCACRAAAACCACRRN
NYYGTGGTTTTYGTGGTTWN		 SELEX
Yin et al.(2017)
RUNX2_eDBD_Methyl-HT-SELEX 		0.764 0.764
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ISCW023333-PA Runt 238 326

Links

Other Runt family TFs
Other Ixodes scapularis TFs

78 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
TC006536 Tribolium castaneum TC006536 I 0.820
SMAR009403 Strigamia maritima SMAR009403 I 0.815
Hsal_04635--XP_394013.3_APIME Harpegnathos saltator Hsal_04635--XP_394013.3_APIME I 0.809
PPAI010985 Phlebotomus papatasi PPAI010985 I 0.809
runx3 Tetraodon nigroviridis ENSTNIG00000016911 I 0.809
ACEP16391 Atta cephalotes ACEP16391 I 0.809
ENSLACG00000013776 Latimeria chalumnae ENSLACG00000013776 I 0.809
ENSPPYG00000001714 Pongo abelii ENSPPYG00000001714 I 0.798
CLEC011127 Cimex lectularius CLEC011127 I 0.798
AEPI011470 Anopheles epiroticus AEPI011470 I 0.793
ACYPI007541 Acyrthosiphon pisum ACYPI007541 I 0.787
ACYPI001442 Acyrthosiphon pisum ACYPI001442 I 0.787
SINV13345 Solenopsis invicta SINV13345 I 0.783
HMEL009843 Heliconius melpomene HMEL009843 I 0.779
ASIS002518 Anopheles sinensis ASIS002518 I 0.777
AALB007753 Anopheles albimanus AALB007753 I 0.777
Runx1 Mus musculus ENSMUSG00000022952 D 0.775
Cflo_03909--XP_394016.2_APIME Camponotus floridanus Cflo_03909--XP_394016.2_APIME I 0.775
MCINX000302 Melitaea cinxia MCINX000302 I 0.775
SINV13317 Solenopsis invicta SINV13317 I 0.775
Hsal_12319--XP_394016.2_APIME Harpegnathos saltator Hsal_12319--XP_394016.2_APIME I 0.775
runx2a Danio rerio ENSDARG00000040261 I 0.775
RUNX1 Dasypus novemcinctus ENSDNOG00000015041 I 0.775
RUNX1 Tursiops truncatus ENSTTRG00000014160 I 0.775
ENSLACG00000015930 Latimeria chalumnae ENSLACG00000015930 I 0.775
CpipJ_CPIJ016826 Culex pipiens CpipJ_CPIJ016826 I 0.768
CPIJ016826 Culex quinquefasciatus CPIJ016826 I 0.768
AQUA008686 Anopheles quadriannulatus AQUA008686 I 0.768
XP_002939387 Xenopus tropicalis XP_002939387 I 0.764
XP_002939386 Xenopus tropicalis XP_002939386 I 0.764
Ocbimv22002042m.g Octopus bimaculoides Ocbimv22002042m.g I 0.764
RPRC005391 Rhodnius prolixus RPRC005391 I 0.764
RUNX1 Pteropus vampyrus ENSPVAG00000001606 I 0.764
Runx2 Mus musculus ENSMUSG00000039153 D 0.764
RUNX2 Homo sapiens ENSG00000124813 D 0.764
ENSSHAG00000014782 Sarcophilus harrisii ENSSHAG00000014782 I 0.764
RUNX1 Monodelphis domestica ENSMODG00000021051 I 0.764
RPRC000026 Rhodnius prolixus RPRC000026 I 0.755
Gfo_R015914 Geospiza fortis Gfo_R015914 I 0.755
TC006542 Tribolium castaneum TC006542 I 0.753
CPIJ006369 Culex quinquefasciatus CPIJ006369 I 0.753
runx2b Danio rerio ENSDARG00000059233 I 0.753
CpipJ_CPIJ006369 Culex pipiens CpipJ_CPIJ006369 I 0.753
ENSAMXG00000017349 Astyanax mexicanus ENSAMXG00000017349 I 0.753
AARA011332 Anopheles arabiensis AARA011332 I 0.753
runx2b Gasterosteus aculeatus ENSGACG00000012322 I 0.753
RUNX1 Homo sapiens ENSG00000159216 D 0.750
AFAF002111 Anopheles farauti AFAF002111 I 0.745
ACHR007816 Anopheles christyi ACHR007816 I 0.745
LCUP002657 Lucilia cuprina LCUP002657 I 0.740
RUNX2 Pteropus vampyrus ENSPVAG00000001720 I 0.739
ADIR001029 Anopheles dirus ADIR001029 I 0.737
AFUN010424 Anopheles funestus AFUN010424 I 0.737
MESCA007079 Megaselia scalaris MESCA007079 I 0.733
runx1 Takifugu rubripes ENSTRUG00000012611 I 0.730
LLOJ002049 Lutzomyia longipalpis LLOJ002049 I 0.727
LDEC003023 Leptinotarsa decemlineata LDEC003023 I 0.726
ENSSSCG00000025261 Sus scrofa ENSSSCG00000025261 I 0.724
BGIBMGA008970 Bombyx mori BGIBMGA008970 I 0.723
ACUA002933 Anopheles culicifacies ACUA002933 I 0.723
ENSMPUG00000015804 Mustela putorius furo ENSMPUG00000015804 I 0.719
ENSTRUG00000017865 Takifugu rubripes ENSTRUG00000017865 I 0.719
CLEC011123 Cimex lectularius CLEC011123 I 0.713
runx1 Danio rerio ENSDARG00000087646 I 0.713
LDEC006650 Leptinotarsa decemlineata LDEC006650 I 0.710
LDEC020505 Leptinotarsa decemlineata LDEC020505 I 0.710
AMIN005760 Anopheles minimus AMIN005760 I 0.709
AQUA009970 Anopheles quadriannulatus AQUA009970 I 0.708
PHUM333310 Pediculus humanus PHUM333310 I 0.708
AGAP001094 Anopheles gambiae AGAP001094 I 0.708
ACUA000036 Anopheles culicifacies ACUA000036 I 0.708
AMEM004753 Anopheles merus AMEM004753 I 0.708
ACOM031089 Anopheles coluzzii ACOM031089 I 0.708
AARA011472 Anopheles arabiensis AARA011472 I 0.708
AMEC007551 Anopheles melas AMEC007551 I 0.708
KGM_02818 Danaus plexippus KGM_02818 I 0.704
LCUP002652 Lucilia cuprina LCUP002652 I 0.702
AMEC011614 Anopheles melas AMEC011614 I 0.702