RUNX2 (Homo sapiens)
Runt

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00853 (Runt) IPR013524 ENSG00000124813 T319383_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
RUNX2
M03468_2.00
Homo sapiens
HRACCGCAAACCRCRD

HYGYGGTTTGCGGTYD
SELEX
Jolma et al.(2013)
RUNX2_1
(Direct) (Direct)
RUNX2
M03469_2.00
Homo sapiens
HRACCRCADWWACCRCAD

HTGYGGTWWHTGYGGTYD
SELEX
Jolma et al.(2013)
RUNX2_2
(Direct) (Direct)
RUNX2
M03470_2.00
Homo sapiens
WAACCRCAR

YTGYGGTTW
SELEX
Jolma et al.(2013)
RUNX2_3
(Direct) (Direct)
RUNX2
M05733_2.00
Homo sapiens
NHRACCRCADWAACCRCAVN

NBTGYGGTTWHTGYGGTYDN
SELEX
Yin et al.(2017)
RUNX2_eDBD_HT-SELEX
(Direct) (Direct)
RUNX2
M05734_2.00
Homo sapiens
NWAACCACRAAAACCACRRN

NYYGTGGTTTTYGTGGTTWN
SELEX
Yin et al.(2017)
RUNX2_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
RUNX2
M09370_2.00
Homo sapiens
MMHAACCACAVVMH

DKBBTGTGGTTDKK
Misc
Kulakovskiy et al.(2013)
RUNX2_HUMAN.H11MO.0.A
(Direct) (Direct)
RUNX2
M09630_2.00
Homo sapiens
NHVACCACANNN

NNNTGTGGTBDN
Misc
Heinz et al.(2010)
PCa-RUNX2_GSE33889
(Direct) (Direct)
RUNX2
M11255_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML3_Q3
(Direct) (Direct)
RUNX2
M11256_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML3_Q6
(Direct) (Direct)
RUNX2
M11257_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$OSF2_Q6
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Runx2
M01307_2.00
Mus musculus
NHDACCRCAN

NTGYGGTHDN
PBM
Lambert et al.(2019)
pTH9764
1.000 1.000
Runx2
M09373_2.00
Mus musculus
VWRACCACARVV

BBYTGTGGTYWB
Misc
Kulakovskiy et al.(2013)
RUNX2_MOUSE.H11MO.0.A
1.000 1.000
RUNX3
M03464_2.00
Homo sapiens
HRACCGCAAACCRCAN

NTGYGGTTTGCGGTYD
SELEX
Jolma et al.(2013)
RUNX3_1
0.946 0.946
RUNX3
M03465_2.00
Homo sapiens
WAACCRCARN

NYTGYGGTTW
SELEX
Jolma et al.(2013)
RUNX3_2
0.946 0.946
RUNX3
M03466_2.00
Homo sapiens
HDACCRCADWAACCRCRN

NYGYGGTTWHTGYGGTHD
SELEX
Jolma et al.(2013)
RUNX3_3
0.946 0.946
RUNX3
M03467_2.00
Homo sapiens
HRACCRCAAH

DTTGYGGTYD
SELEX
Jolma et al.(2013)
RUNX3_4
0.946 0.946
RUNX3
M02751_2.00
Homo sapiens
WACCRCAM

KTGYGGTW
SELEX
Jolma et al.(2010)
RUNX3_monomer
0.946 0.946
RUNX3
M05731_2.00
Homo sapiens
YWAACCGCAAAAACCGCARV

BYTGCGGTTTTTGCGGTTWR
SELEX
Yin et al.(2017)
RUNX3_FL_HT-SELEX
0.946 0.946
RUNX3
M09369_2.00
Homo sapiens
HAACCACARN

NYTGTGGTTD
Misc
Kulakovskiy et al.(2013)
RUNX3_HUMAN.H11MO.0.A
0.946 0.946
Runx3
M09374_2.00
Mus musculus
NHRACCACARVN

NBYTGTGGTYDN
Misc
Kulakovskiy et al.(2013)
RUNX3_MOUSE.H11MO.0.A
0.946 0.946
RUNX3
M11252_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML2_Q3_01
0.946 0.946
RUNX3
M11253_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML2_Q3
0.946 0.946
RUNX3
M11254_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML2_Q4
0.946 0.946
RUNX3
M05732_2.00
Homo sapiens
HWAACCACRAAAACCACRARN

NYTYGTGGTTTTYGTGGTTWD
SELEX
Yin et al.(2017)
RUNX3_FL_Methyl-HT-SELEX
0.946 0.946
Runx1
M08163_2.00
Mus musculus
HRRCCACARVN

NBYTGTGGYYD
ChIP-seq
Mathelier et al.(2014)
MA0002.2
0.923 0.923
RUNX1
M09371_2.00
Homo sapiens
NWAACCACARV

BYTGTGGTTWN
Misc
Kulakovskiy et al.(2013)
RUNX1_HUMAN.H11MO.0.A
0.923 0.923
Runx1
M09372_2.00
Mus musculus
VWRACCACARVV

BBYTGTGGTYWB
Misc
Kulakovskiy et al.(2013)
RUNX1_MOUSE.H11MO.0.A
0.923 0.923
RUNX1
M09632_2.00
Homo sapiens
HAACCACADV

BHTGTGGTTD
Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE29180
0.923 0.923
RUNX1
M09631_2.00
Homo sapiens
VCCACWTCCTBY

RVAGGAWGTGGB
Misc
Heinz et al.(2010)
Jurkat-RUNX1_GSE17954
0.923 0.923
Runx1
M09633_2.00
Mus musculus
NWAACCACAR

YTGTGGTTWN
Misc
Heinz et al.(2010)
HPC7-Runx1_GSE22178
0.923 0.923
RUNX1
M11258_2.00
Homo sapiens
ACCRCA

TGYGGT
Transfac
Matys et al.(2006)
V$AML1_01
0.923 0.923
RUNX1
M11259_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q4_01
0.923 0.923
RUNX1
M11260_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q4_02
0.923 0.923
RUNX1
M11261_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q4
0.923 0.923
RUNX1
M11262_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q5
0.923 0.923
RUNX1
M11263_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$AML1_Q6
0.923 0.923
lz
M03964_2.00
Drosophila melanogaster
HRACCGCAAHM

KDTTGCGGTYD
SELEX
Nitta et al.(2015)
lz_1
0.731 0.731
lz
M03965_2.00
Drosophila melanogaster
HVACCRCARWAACCRCAV

BTGYGGTTWYTGYGGTBD
SELEX
Nitta et al.(2015)
lz_2
0.731 0.731
lz
M03966_2.00
Drosophila melanogaster
WRACCRCAWTAACCRCAA

TTGYGGTTAWTGYGGTYW
SELEX
Nitta et al.(2015)
lz_3
0.731 0.731
lz
M03967_2.00
Drosophila melanogaster
HRACCGCAAAACCRCAR

YTGYGGTTTTGCGGTYD
SELEX
Nitta et al.(2015)
lz_4
0.731 0.731
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000352514 Runt 88 217
ENSP00000360486 Runt 102 231
ENSP00000360491 Runt 102 231
ENSP00000360493 Runt 102 231
ENSP00000420707 Runt 102 231
ENSP00000458178 Runt 102 231
ENSP00000460188 Runt 88 217
ENSP00000485863 Runt 88 217

Links

Other Runt family TFs
Other Homo sapiens TFs

364 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSSHAG00000009950 Sarcophilus harrisii ENSSHAG00000009950 I 1.000
Runx2 Rattus norvegicus ENSRNOG00000020193 I 1.000
RUNX2 Pteropus vampyrus ENSPVAG00000001720 I 1.000
RUNX2 Monodelphis domestica ENSMODG00000018912 I 1.000
ENSSSCG00000025551 Sus scrofa ENSSSCG00000025551 I 1.000
RUNX2 Tupaia belangeri ENSTBEG00000000948 I 1.000
ENSSTOG00000010163 Ictidomys tridecemlineatus ENSSTOG00000010163 I 1.000
RUNX2 Pan troglodytes ENSPTRG00000018228 I 1.000
ENSPPYG00000016664 Pongo abelii ENSPPYG00000016664 I 1.000
RUNX2 Ochotona princeps ENSOPRG00000002943 I 1.000
ENSAMEG00000009223 Ailuropoda melanoleuca ENSAMEG00000009223 I 1.000
ENSOCUG00000011739 Oryctolagus cuniculus ENSOCUG00000011739 I 1.000
RUNX2 Ornithorhynchus anatinus ENSOANG00000008265 I 1.000
Runx2 Mus musculus ENSMUSG00000039153 D 1.000
ENSPANG00000006186 Papio anubis ENSPANG00000006186 I 1.000
RUNX2 Bos taurus ENSBTAG00000004104 I 1.000
RUNX2 Macaca mulatta ENSMMUG00000019819 I 1.000
ENSBTAP00000006227-D1 Bos grunniens ENSBTAP00000006227-D1 I 1.000
RUNX2 Cavia porcellus ENSCPOG00000005277 I 1.000
RUNX2 Felis catus ENSFCAG00000022480 I 1.000
RUNX2 Erinaceus europaeus ENSEEUG00000009243 I 1.000
RUNX2 Dasypus novemcinctus ENSDNOG00000034361 I 1.000
ENSCSAG00000012528 Chlorocebus sabaeus ENSCSAG00000012528 I 1.000
RUNX2 Otolemur garnettii ENSOGAG00000003900 I 1.000
RUNX2 Myotis lucifugus ENSMLUG00000000514 I 1.000
RUNX2 Tursiops truncatus ENSTTRG00000006943 I 1.000
RUNX2 Gorilla gorilla ENSGGOG00000012890 I 1.000
ENSLOCG00000015816 Lepisosteus oculatus ENSLOCG00000015816 I 1.000
RUNX2 Loxodonta africana ENSLAFG00000005054 I 1.000
ENSLACG00000011545 Latimeria chalumnae ENSLACG00000011545 I 1.000
runx2a Danio rerio ENSDARG00000040261 I 0.992
RUNX2 Anolis carolinensis ENSACAG00000013003 I 0.992
Myotis_brandtii_RUNX2_10026084 Myotis brandtii Myotis_brandtii_RUNX2_10026084 I 0.992
Cmyd_10020455 Chelonia mydas Cmyd_10020455 I 0.992
Pvit_01165 Pogona vitticeps Pvit_01165 I 0.992
RUNX2 Taeniopygia guttata ENSTGUG00000013249 I 0.992
Afo_R008955 Aptenodytes forsteri Afo_R008955 I 0.988
ENSAMXG00000017349 Astyanax mexicanus ENSAMXG00000017349 I 0.985
runx2b Danio rerio ENSDARG00000059233 I 0.985
Aan_R005895 Calypte anna Aan_R005895 I 0.978
ENSAPLG00000011653 Anas platyrhynchos ENSAPLG00000011653 I 0.978
Brh_R000794 Buceros rhinoceros Brh_R000794 I 0.978
RUNX2 Meleagris gallopavo ENSMGAG00000014267 I 0.978
ENSSHAG00000012559 Sarcophilus harrisii ENSSHAG00000012559 I 0.978
Tal_R011874 Tyto alba Tal_R011874 I 0.978
Alligator_sinensis_CCG001676.1 Alligator sinensis Alligator_sinensis_CCG001676.1 I 0.977
runx2.L Xenopus laevis XB-GENE-864817 I 0.977
Gfo_R013848 Geospiza fortis Gfo_R013848 I 0.974
ENSMGAG00000002035 Meleagris gallopavo ENSMGAG00000002035 I 0.974
Alligator_sinensis_CCG010991.1 Alligator sinensis Alligator_sinensis_CCG010991.1 I 0.973
ENSPFOG00000016115 Poecilia formosa ENSPFOG00000016115 I 0.969
runx2 Oryzias latipes ENSORLG00000010169 I 0.969
runx2 Takifugu rubripes ENSTRUG00000003501 I 0.969
ENSXMAG00000003400 Xiphophorus maculatus ENSXMAG00000003400 I 0.969
ENSGMOG00000010468 Gadus morhua ENSGMOG00000010468 I 0.969
ENSONIG00000001025 Oreochromis niloticus ENSONIG00000001025 I 0.969
runx2b Tetraodon nigroviridis ENSTNIG00000009685 I 0.969
ENSAMXG00000000881 Astyanax mexicanus ENSAMXG00000000881 I 0.969
ENSNLEG00000009021 Nomascus leucogenys ENSNLEG00000009021 I 0.967
ENSPSIG00000014293 Pelodiscus sinensis ENSPSIG00000014293 I 0.967
ENSMPUG00000015804 Mustela putorius furo ENSMPUG00000015804 I 0.966
ENSSTOG00000020082 Ictidomys tridecemlineatus ENSSTOG00000020082 I 0.965
ENSTRUG00000017865 Takifugu rubripes ENSTRUG00000017865 I 0.963
runx2 Xenopus tropicalis XB-GENE-482021 I 0.962
runx2b Gasterosteus aculeatus ENSGACG00000012322 I 0.962
ENSCAFG00000031052 Canis familiaris ENSCAFG00000031052 I 0.960
RUNX1 Callithrix jacchus ENSCJAG00000002816 I 0.960
RUNX1 Macaca mulatta ENSMMUG00000001649 I 0.960
RUNX3 Anolis carolinensis ENSACAG00000017855 I 0.957
ENSFCAG00000029032 Felis catus ENSFCAG00000029032 I 0.954
ENSOANG00000031074 Ornithorhynchus anatinus ENSOANG00000031074 I 0.947
CABZ01102124.1 Danio rerio ENSDARG00000103592 I 0.947
ENSAPLG00000007026 Anas platyrhynchos ENSAPLG00000007026 I 0.947
RUNX3 Callithrix jacchus ENSCJAG00000020815 I 0.946
ENSPANG00000008140 Papio anubis ENSPANG00000008140 I 0.946
RUNX3 Ochotona princeps ENSOPRG00000011273 I 0.946
RUNX3 Canis familiaris ENSCAFG00000012903 I 0.946
RUNX3 Tursiops truncatus ENSTTRG00000009396 I 0.946
Runx3 Mus musculus ENSMUSG00000070691 D 0.946
RUNX3 Oryctolagus cuniculus ENSOCUG00000017751 I 0.946
RUNX3 Gorilla gorilla ENSGGOG00000004848 I 0.946
RUNX3 Otolemur garnettii ENSOGAG00000025633 I 0.946
ENSAMEG00000010102 Ailuropoda melanoleuca ENSAMEG00000010102 I 0.946
ENSCPOG00000000551 Cavia porcellus ENSCPOG00000000551 I 0.946
RUNX3 Homo sapiens ENSG00000020633 D 0.946
RUNX3 Felis catus ENSFCAG00000000680 I 0.946
RUNX3 Pan troglodytes ENSPTRG00000000351 I 0.946
Runx3 Rattus norvegicus ENSRNOG00000054217 I 0.946
ENSSTOG00000022471 Ictidomys tridecemlineatus ENSSTOG00000022471 I 0.946
ENSCSAG00000000947 Chlorocebus sabaeus ENSCSAG00000000947 I 0.946
RUNX3 Bos taurus ENSBTAG00000019800 I 0.945
Afo_R004888 Aptenodytes forsteri Afo_R004888 I 0.944
Aan_R007315 Calypte anna Aan_R007315 I 0.944
Brh_R001637 Buceros rhinoceros Brh_R001637 I 0.944
RUNX3 Macaca mulatta ENSMMUG00000002420 I 0.938
Cmyd_10020845 Chelonia mydas Cmyd_10020845 I 0.938
RUNX3 Dasypus novemcinctus ENSDNOG00000043493 I 0.938
Pvit_17193 Pogona vitticeps Pvit_17193 I 0.938
ENSAPLG00000016439 Anas platyrhynchos ENSAPLG00000016439 I 0.938
ENSMODG00000013941 Monodelphis domestica ENSMODG00000013941 I 0.938
ENSFALG00000000470 Ficedula albicollis ENSFALG00000000470 I 0.938
runx3 Takifugu rubripes ENSTRUG00000001517 I 0.938
RUNX3 Loxodonta africana ENSLAFG00000008382 I 0.938
RUNX3 Taeniopygia guttata ENSTGUG00000001130 I 0.938
ENSPPYG00000001714 Pongo abelii ENSPPYG00000001714 I 0.938
runx3 Tetraodon nigroviridis ENSTNIG00000016911 I 0.938
ENSGALG00000026821 Gallus gallus ENSGALG00000026821 I 0.938
RUNX2 Equus caballus ENSECAG00000020875 I 0.937
ENSMGAG00000014534 Meleagris gallopavo ENSMGAG00000014534 I 0.933
runx3 Oryzias latipes ENSORLG00000017515 I 0.931
ENSONIG00000008210 Oreochromis niloticus ENSONIG00000008210 I 0.931
ENSAMXG00000004048 Astyanax mexicanus ENSAMXG00000004048 I 0.931
ENSPSIG00000012728 Pelodiscus sinensis ENSPSIG00000012728 I 0.931
ENSPFOG00000003997 Poecilia formosa ENSPFOG00000003997 I 0.931
runx3 Xenopus tropicalis XB-GENE-487784 I 0.931
ENSXMAG00000018835 Xiphophorus maculatus ENSXMAG00000018835 I 0.931
runx3 Danio rerio ENSDARG00000052826 I 0.931
ENSMEUG00000014419 Macropus eugenii ENSMEUG00000014419 I 0.931
ENSLOCG00000002744 Lepisosteus oculatus ENSLOCG00000002744 I 0.931
ENSCPOG00000002684 Cavia porcellus ENSCPOG00000002684 I 0.931
runx3 Gasterosteus aculeatus ENSGACG00000007301 I 0.931
Cmyd_10021516 Chelonia mydas Cmyd_10021516 I 0.923
ENSPANG00000007357 Papio anubis ENSPANG00000007357 I 0.923
Runx1 Rattus norvegicus ENSRNOG00000001704 I 0.923
Runx1 Mus musculus ENSMUSG00000022952 D 0.923
Runx1 Dipodomys ordii ENSDORG00000004347 I 0.923
RUNX1 Loxodonta africana ENSLAFG00000004290 I 0.923
ENSGMOG00000019132 Gadus morhua ENSGMOG00000019132 I 0.923
RUNX1 Gorilla gorilla ENSGGOG00000012862 I 0.923
RUNX1 Gallus gallus ENSGALG00000016022 I 0.923
RUNX1 Pan troglodytes ENSPTRG00000013883 I 0.923
ENSPSIG00000017547 Pelodiscus sinensis ENSPSIG00000017547 I 0.923
ENSPPYG00000011394 Pongo abelii ENSPPYG00000011394 I 0.923
RUNX1 Homo sapiens ENSG00000159216 D 0.923
ENSCSAG00000008703 Chlorocebus sabaeus ENSCSAG00000008703 I 0.923
ENSAMEG00000005325 Ailuropoda melanoleuca ENSAMEG00000005325 I 0.923
ENSFALG00000000025 Ficedula albicollis ENSFALG00000000025 I 0.923
Pvit_04762 Pogona vitticeps Pvit_04762 I 0.923
RUNX1 Canis familiaris ENSCAFG00000009596 I 0.923
RUNX1 Microcebus murinus ENSMICG00000011998 I 0.923
RUNX1 Oryctolagus cuniculus ENSOCUG00000013731 I 0.923
RUNX1 Otolemur garnettii ENSOGAG00000033362 I 0.923
ENSNLEG00000004310 Nomascus leucogenys ENSNLEG00000004310 I 0.923
Ogr17914 Ophisaurus gracilis Ogr17914 I 0.923
ENSSSCG00000012051 Sus scrofa ENSSSCG00000012051 I 0.923
RUNX1 Tursiops truncatus ENSTTRG00000014160 I 0.921
XP_002939386 Xenopus tropicalis XP_002939386 I 0.915
RUNX1 Monodelphis domestica ENSMODG00000021051 I 0.915
RUNX1 Pteropus vampyrus ENSPVAG00000001606 I 0.915
ENSMPUG00000001340 Mustela putorius furo ENSMPUG00000001340 I 0.915
RUNX1 Equus caballus ENSECAG00000003462 I 0.915
ENSSHAG00000014782 Sarcophilus harrisii ENSSHAG00000014782 I 0.915
RUNX1 Dasypus novemcinctus ENSDNOG00000015041 I 0.915
runx3.L Xenopus laevis XB-GENE-6487158 I 0.915
RUNX1 Bos taurus ENSBTAG00000004742 I 0.915
runx1.L Xenopus laevis XB-GENE-864949 I 0.915
XP_002939387 Xenopus tropicalis XP_002939387 I 0.915
Gfo_R015914 Geospiza fortis Gfo_R015914 I 0.915
ENSP00000300305 Macaca fascicularis ENSP00000300305 I 0.915
ENSP00000409227-D1 Bos grunniens ENSP00000409227-D1 I 0.915
ENSOPRG00000000765 Ochotona princeps ENSOPRG00000000765 I 0.915
ENSLOCG00000010990 Lepisosteus oculatus ENSLOCG00000010990 I 0.915
ENSLACG00000013776 Latimeria chalumnae ENSLACG00000013776 I 0.913
Gfo_R011596 Geospiza fortis Gfo_R011596 I 0.909
RUNX1 Procavia capensis ENSPCAG00000016747 I 0.908
ENSOARG00000006421 Ovis aries ENSOARG00000006421 I 0.908
ENSFALG00000001493 Ficedula albicollis ENSFALG00000001493 I 0.907
estExt_fgenesh2_kg.C_750001 Branchiostoma floridae estExt_fgenesh2_kg.C_750001 I 0.900
estExt_fgenesh2_kg.C_3770001 Branchiostoma floridae estExt_fgenesh2_kg.C_3770001 I 0.900
ENSTSYG00000005097 Tarsius syrichta ENSTSYG00000005097 I 0.900
XP_002939388 Xenopus tropicalis XP_002939388 I 0.900
ENSGALG00000026484 Gallus gallus ENSGALG00000026484 I 0.892
ENSAMXG00000012244 Astyanax mexicanus ENSAMXG00000012244 I 0.892
ENSSSCG00000025261 Sus scrofa ENSSSCG00000025261 I 0.888
ENSTNIG00000018690 Tetraodon nigroviridis ENSTNIG00000018690 I 0.885
ENSGMOG00000014088 Gadus morhua ENSGMOG00000014088 I 0.885
ENSONIG00000004914 Oreochromis niloticus ENSONIG00000004914 I 0.885
Afo_R012718 Aptenodytes forsteri Afo_R012718 I 0.885
RUNX1 Gasterosteus aculeatus ENSGACG00000015276 I 0.885
ENSLACG00000015930 Latimeria chalumnae ENSLACG00000015930 I 0.885
ENSTGUG00000004719 Taeniopygia guttata ENSTGUG00000004719 I 0.883
RUNX2 Sus scrofa ENSSSCG00000001710 I 0.878
runx1 Takifugu rubripes ENSTRUG00000012611 I 0.877
RUNX3 Myotis lucifugus ENSMLUG00000003395 I 0.877
RUNX1 Oryzias latipes ENSORLG00000020699 I 0.877
ENSXMAG00000004396 Xiphophorus maculatus ENSXMAG00000004396 I 0.877
ENSPFOG00000008944 Poecilia formosa ENSPFOG00000008944 I 0.877
ENSP00000352514 Macaca fascicularis ENSP00000352514 I 0.876
Gfo_R000714 Geospiza fortis Gfo_R000714 I 0.871
ENSP00000382800 Macaca fascicularis ENSP00000382800 I 0.867
ENSCING00000002253 Ciona intestinalis ENSCING00000002253 I 0.867
runx1 Danio rerio ENSDARG00000087646 I 0.862
ENSNLEG00000003611 Nomascus leucogenys ENSNLEG00000003611 I 0.843
ENSMPUG00000012508 Mustela putorius furo ENSMPUG00000012508 I 0.828
Sakowv30005496m.g Saccoglossus kowalevskii Sakowv30005496m.g I 0.823
Aan_R002212 Calypte anna Aan_R002212 I 0.805
MESCA007079 Megaselia scalaris MESCA007079 I 0.800
LLOJ002717 Lutzomyia longipalpis LLOJ002717 I 0.797
NEMVEDRAFT_v1g129231 Nematostella vectensis NEMVEDRAFT_v1g129231 I 0.792
RPRC005391 Rhodnius prolixus RPRC005391 I 0.785
Hsal_12319--XP_394016.2_APIME Harpegnathos saltator Hsal_12319--XP_394016.2_APIME I 0.785
TriadG25179 Trichoplax adhaerens TriadG25179 I 0.785
SINV13317 Solenopsis invicta SINV13317 I 0.785
Cflo_03909--XP_394016.2_APIME Camponotus floridanus Cflo_03909--XP_394016.2_APIME I 0.785
ENSOARG00000010358 Ovis aries ENSOARG00000010358 I 0.783
SMAR009403 Strigamia maritima SMAR009403 I 0.783
XP_002165633.1 Hydra magnipapillata XP_002165633.1 I 0.783
GB52721 Apis mellifera GB52721 I 0.777
NV17793 Nasonia vitripennis NV17793 I 0.769
TC005566 Tribolium castaneum TC005566 I 0.769
TC005796 Tribolium castaneum TC005796 I 0.769
NV11000 Nasonia vitripennis NV11000 I 0.769
YQE_12218 Dendroctonus ponderosae YQE_12218 I 0.769
HMEL009842 Heliconius melpomene HMEL009842 I 0.769
RPRC000026 Rhodnius prolixus RPRC000026 I 0.766
ISCW023333 Ixodes scapularis ISCW023333 I 0.764
SPU_006917 Strongylocentrotus purpuratus SPU_006917 I 0.762
TC006536 Tribolium castaneum TC006536 I 0.762
SINV13363 Solenopsis invicta SINV13363 I 0.762
GB52761 Apis mellifera GB52761 I 0.762
ASTEI07771 Anopheles stephensi ASTEI07771 I 0.762
AATE002063 Anopheles atroparvus AATE002063 I 0.762
AAEL006160 Aedes aegypti AAEL006160 I 0.762
PHUM333300 Pediculus humanus PHUM333300 I 0.762
Hsal_12322--XP_394014.2_APIME Harpegnathos saltator Hsal_12322--XP_394014.2_APIME I 0.762
ACEP16400 Atta cephalotes ACEP16400 I 0.762
KGM_21075 Danaus plexippus KGM_21075 I 0.762
PHUM333320 Pediculus humanus PHUM333320 I 0.762
tetur01g02340 Tetranychus urticae tetur01g02340 I 0.762
Cflo_03911--XP_394014.2_APIME Camponotus floridanus Cflo_03911--XP_394014.2_APIME I 0.754
ENSOARG00000013599 Ovis aries ENSOARG00000013599 I 0.754
GB52718 Apis mellifera GB52718 I 0.754
AEPI011470 Anopheles epiroticus AEPI011470 I 0.750
ISCW004493 Ixodes scapularis ISCW004493 I 0.750
ADIR002675 Anopheles dirus ADIR002675 I 0.750
SINV13345 Solenopsis invicta SINV13345 I 0.750
GD16951 Drosophila simulans FBgn0188530 I 0.748
CpipJ_CPIJ016826 Culex pipiens CpipJ_CPIJ016826 I 0.747
CPIJ016826 Culex quinquefasciatus CPIJ016826 I 0.747
HMEL009843 Heliconius melpomene HMEL009843 I 0.747
NV10998 Nasonia vitripennis NV10998 I 0.746
Cflo_03913--XP_394013.3_APIME Camponotus floridanus Cflo_03913--XP_394013.3_APIME I 0.746
ACYPI006937 Acyrthosiphon pisum ACYPI006937 I 0.746
MDOA011942 Musca domestica MDOA011942 I 0.746
Hsal_04635--XP_394013.3_APIME Harpegnathos saltator Hsal_04635--XP_394013.3_APIME I 0.746
GL16499 Drosophila persimilis FBgn0154103 I 0.746
GM22662 Drosophila sechellia FBgn0177532 I 0.746
GJ18917 Drosophila virilis FBgn0206063 I 0.746
GK20052 Drosophila willistoni FBgn0222049 I 0.746
GE15340 Drosophila yakuba FBgn0232921 I 0.746
GL15927 Drosophila persimilis FBgn0153531 I 0.746
GI15119 Drosophila mojavensis FBgn0137869 I 0.746
ENSONIG00000001436 Oreochromis niloticus ENSONIG00000001436 I 0.746
RunxA Drosophila melanogaster FBgn0083981 I 0.746
GG17578 Drosophila erecta FBgn0109803 I 0.746
GH17774 Drosophila grimshawi FBgn0125244 I 0.746
GA22609 Drosophila pseudoobscura FBgn0244012 I 0.746
GF15983 Drosophila ananassae FBgn0093006 I 0.746
GA25684 Drosophila pseudoobscura FBgn0247061 I 0.746
ENSCSAVG00000004072 Ciona savignyi ENSCSAVG00000004072 I 0.746
ASIS002518 Anopheles sinensis ASIS002518 I 0.745
AALB007753 Anopheles albimanus AALB007753 I 0.745
LCUP002647 Lucilia cuprina LCUP002647 I 0.744
ACYPI001442 Acyrthosiphon pisum ACYPI001442 I 0.738
PHUM333340 Pediculus humanus PHUM333340 I 0.738
GJ18742 Drosophila virilis FBgn0205894 I 0.738
ACYPI007541 Acyrthosiphon pisum ACYPI007541 I 0.738
GK25373 Drosophila willistoni FBgn0227332 I 0.738
CapteG142159 Capitella teleta CapteG142159 I 0.738
LCUP002656 Lucilia cuprina LCUP002656 I 0.738
MCINX000302 Melitaea cinxia MCINX000302 I 0.738
GI14398 Drosophila mojavensis FBgn0137150 I 0.738
AQUA008686 Anopheles quadriannulatus AQUA008686 I 0.737
LDEC003023 Leptinotarsa decemlineata LDEC003023 I 0.737
CLEC011127 Cimex lectularius CLEC011127 I 0.737
KGM_02818 Danaus plexippus KGM_02818 I 0.735
SNAPOd2T00000189001 Oikopleura dioica SNAPOd2T00000189001 I 0.733
AFAF013225 Anopheles farauti AFAF013225 I 0.732
CPIJ019508 Culex quinquefasciatus CPIJ019508 I 0.731
GM22478 Drosophila sechellia FBgn0177348 I 0.731
GE17788 Drosophila yakuba FBgn0235232 I 0.731
CpipJ_CPIJ019508 Culex pipiens CpipJ_CPIJ019508 I 0.731
lz Drosophila melanogaster FBgn0002576 D 0.731
AALB009220 Anopheles albimanus AALB009220 I 0.731
GG18309 Drosophila erecta FBgn0110525 I 0.731
DAPPUDRAFT_290557 Daphnia pulex DAPPUDRAFT_290557 I 0.730
MESCA007078 Megaselia scalaris MESCA007078 I 0.730
ADIR002676 Anopheles dirus ADIR002676 I 0.730
RUNX1 Myotis lucifugus ENSMLUG00000005802 I 0.729
ACEP16409 Atta cephalotes ACEP16409 I 0.727
CpipJ_CPIJ006369 Culex pipiens CpipJ_CPIJ006369 I 0.726
CPIJ006369 Culex quinquefasciatus CPIJ006369 I 0.726
AALB007752 Anopheles albimanus AALB007752 I 0.725
PPAI007797 Phlebotomus papatasi PPAI007797 I 0.725
CpipJ_CPIJ006373 Culex pipiens CpipJ_CPIJ006373 I 0.725
Ocbimv22002042m.g Octopus bimaculoides Ocbimv22002042m.g I 0.725
CLEC011124 Cimex lectularius CLEC011124 I 0.725
CPIJ006373 Culex quinquefasciatus CPIJ006373 I 0.725
ACEP16391 Atta cephalotes ACEP16391 I 0.724
ACHR007816 Anopheles christyi ACHR007816 I 0.724
AARA004356 Anopheles arabiensis AARA004356 I 0.723
AEPI003479 Anopheles epiroticus AEPI003479 I 0.723
ACHR004078 Anopheles christyi ACHR004078 I 0.723
ENSXMAG00000006715 Xiphophorus maculatus ENSXMAG00000006715 I 0.723
AAEL007040 Aedes aegypti AAEL007040 I 0.723
AMIN002518 Anopheles minimus AMIN002518 I 0.723
ASTEI07959 Anopheles stephensi ASTEI07959 I 0.723
TC006542 Tribolium castaneum TC006542 I 0.723
SPU_007852 Strongylocentrotus purpuratus SPU_007852 I 0.723
AMEM017856 Anopheles merus AMEM017856 I 0.723
LotgiG96224 Lottia gigantea LotgiG96224 I 0.723
AGAP002506 Anopheles gambiae AGAP002506 I 0.723
AARA011332 Anopheles arabiensis AARA011332 I 0.722
AQUA009446 Anopheles quadriannulatus AQUA009446 I 0.720
AMAM011616 Anopheles maculatus AMAM011616 I 0.720
AFUN005474 Anopheles funestus AFUN005474 I 0.717
PPAI005889 Phlebotomus papatasi PPAI005889 I 0.717
ML03045a Mnemiopsis leidyi ML03045a I 0.715
AFAF002111 Anopheles farauti AFAF002111 I 0.714
DAPPUDRAFT_290555 Daphnia pulex DAPPUDRAFT_290555 I 0.714
CLEC011123 Cimex lectularius CLEC011123 I 0.713
CPIJ016825 Culex quinquefasciatus CPIJ016825 I 0.711
CpipJ_CPIJ016825 Culex pipiens CpipJ_CPIJ016825 I 0.711
LDEC020505 Leptinotarsa decemlineata LDEC020505 I 0.710
CLEC011116 Cimex lectularius CLEC011116 I 0.709
MDOA010744 Musca domestica MDOA010744 I 0.708
ENSGACG00000011721 Gasterosteus aculeatus ENSGACG00000011721 I 0.708
PPAI006591 Phlebotomus papatasi PPAI006591 I 0.708
ENSORLG00000018584 Oryzias latipes ENSORLG00000018584 I 0.708
BGLB004758 Biomphalaria glabrata BGLB004758 I 0.708
CGI_10005366 Crassostrea gigas CGI_10005366 I 0.708
GL15800 Drosophila persimilis FBgn0153404 I 0.708
GM23044 Drosophila sechellia FBgn0177912 I 0.708
GH17737 Drosophila grimshawi FBgn0125207 I 0.708
ENSPFOG00000013752 Poecilia formosa ENSPFOG00000013752 I 0.708
GF15967 Drosophila ananassae FBgn0092990 I 0.708
GD17495 Drosophila simulans FBgn0189047 I 0.708
GJ19245 Drosophila virilis FBgn0206390 I 0.708
GB52719 Apis mellifera GB52719 I 0.708
RunxB Drosophila melanogaster FBgn0259162 I 0.708
GE17890 Drosophila yakuba FBgn0235328 I 0.708
GK19810 Drosophila willistoni FBgn0221808 I 0.708
GA13742 Drosophila pseudoobscura FBgn0073778 I 0.708
GG19691 Drosophila erecta FBgn0111893 I 0.708
LCUP002657 Lucilia cuprina LCUP002657 I 0.708
Aqu1.210949 Amphimedon queenslandica Aqu1.210949 I 0.708
LLOJ002049 Lutzomyia longipalpis LLOJ002049 I 0.707
AFUN010424 Anopheles funestus AFUN010424 I 0.707
RUNX1 Sorex araneus ENSSARG00000001700 I 0.705
PPAI010986 Phlebotomus papatasi PPAI010986 I 0.703
ACUA002933 Anopheles culicifacies ACUA002933 I 0.703
BGIBMGA008970 Bombyx mori BGIBMGA008970 I 0.703
LCUP002652 Lucilia cuprina LCUP002652 I 0.702
AMEC011614 Anopheles melas AMEC011614 I 0.702
MCINX005906 Melitaea cinxia MCINX005906 I 0.701
PPAI010985 Phlebotomus papatasi PPAI010985 I 0.701
CpipJ_CPIJ006372 Culex pipiens CpipJ_CPIJ006372 I 0.701
CPIJ006372 Culex quinquefasciatus CPIJ006372 I 0.701
BGIBMGA008906 Bombyx mori BGIBMGA008906 I 0.700
LDEC006650 Leptinotarsa decemlineata LDEC006650 I 0.700
KGM_21065 Danaus plexippus KGM_21065 I 0.700
HMEL014739 Heliconius melpomene HMEL014739 I 0.700
MDOA013149 Musca domestica MDOA013149 I 0.700