ENSP00000374205 (Macaca fascicularis)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00907 (T-box) IPR001699 ENSP00000374205 T341072_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Tbr1
M01028_2.00
Mus musculus
DTVRCAMNYH

DRNKTGYBAH
PBM
SebePedros et al.(2013)
pTH2659
0.920 1.000
TBR1
M03560_2.00
Homo sapiens
AGGTGTGAAN

NTTCACACCT
SELEX
Jolma et al.(2013)
TBR1_1
0.920 1.000
TBR1
M03561_2.00
Homo sapiens
RAGGTGTGAAH

DTTCACACCTY
SELEX
Jolma et al.(2013)
TBR1_2
0.920 1.000
Eomes
M00215_2.00
Mus musculus
RDGTGYBANN

NNTVRCACHY
PBM
Badis et al.(2009)
Eomes_0921
0.865 0.874
EOMES
M03563_2.00
Homo sapiens
DAGGTGTGAWNNN

NNNWTCACACCTH
SELEX
Jolma et al.(2013)
EOMES_1
0.865 0.869
EOMES
M03564_2.00
Homo sapiens
TVACACNTNNNDRNGTGTGA

TCACACNYHNNNANGTGTBA
SELEX
Jolma et al.(2013)
EOMES_2
0.865 0.869
EOMES
M02752_2.00
Homo sapiens
AGGTGTGAW

WTCACACCT
SELEX
Jolma et al.(2010)
EOMES_monomer
0.865 0.869
EOMES
M05807_2.00
Homo sapiens
DAGGTGTGAN

NTCACACCTH
SELEX
Yin et al.(2017)
EOMES_eDBD_HT-SELEX
0.865 0.869
EOMES
M09647_2.00
Homo sapiens
ARGTGWKAAN

NTTMWCACYT
Misc
Heinz et al.(2010)
H9-Eomes_GSE26097
0.865 0.869
EOMES
M05808_2.00
Homo sapiens
NABGTGYKAH

DTMRCACVTN
SELEX
Yin et al.(2017)
EOMES_eDBD_Methyl-HT-SELEX
0.865 0.869
A0A075Q982_PATMI
M00734_2.00
Patiria miniata
NAGGTGTBAN

NTVACACCTN
PBM
Cheatle-Jarvela et al.(2014)
PmTbr
0.789 0.645
TBX21
M03546_2.00
Homo sapiens
GGTGTGAHDTMACACY

RGTGTKAHDTCACACC
SELEX
Jolma et al.(2013)
TBX21_1
0.766 0.732
TBX21
M03547_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_2
0.766 0.732
TBX21
M03548_2.00
Homo sapiens
TMACACYTNNDAGGTGTGA

TCACACCTHNNARGTGTKA
SELEX
Jolma et al.(2013)
TBX21_3
0.766 0.732
TBX21
M03549_2.00
Homo sapiens
GGTGTGAWATCACACC

GGTGTGATWTCACACC
SELEX
Jolma et al.(2013)
TBX21_4
0.766 0.732
TBX21
M03550_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_5
0.766 0.732
TBX21
M03551_2.00
Homo sapiens
TSACACCWNMRAGGTGTGA

TCACACCTYKNWGGTGTSA
SELEX
Jolma et al.(2013)
TBX21_6
0.766 0.732
TBX21
M05793_2.00
Homo sapiens
DAGGTGTKAN

NTMACACCTH
SELEX
Yin et al.(2017)
TBX21_eDBD_HT-SELEX
0.766 0.732
TBX21
M09425_2.00
Homo sapiens
NDSDRGSTGWBRN

NYVWCASCYHSHN
Misc
Kulakovskiy et al.(2013)
TBX21_HUMAN.H11MO.0.A
0.766 0.732
Tbx21
M09428_2.00
Mus musculus
DNDDSTGWSDND

HNHSWCASHHNH
Misc
Kulakovskiy et al.(2013)
TBX21_MOUSE.H11MO.0.A
0.766 0.732
Tbx21
M09648_2.00
Mus musculus
ADGTGWSAHN

NDTSWCACHT
Misc
Heinz et al.(2010)
CD8-Tbet_GSE33802
0.766 0.732
TBX21
M05794_2.00
Homo sapiens
DASGTGTKAW

WTMACACSTH
SELEX
Yin et al.(2017)
TBX21_eDBD_Methyl-HT-SELEX
0.766 0.732
SPU_025584
M00733_2.00
Strongylocentrotus purpuratus
RGGTGTGANN

NNTCACACCY
PBM
Cheatle-Jarvela et al.(2014)
SpTbr
0.762 0.617
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000374205 T-box 206 393

Links

Other T-box family TFs
Other Macaca fascicularis TFs

166 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Alligator_sinensis_CCG012491.1 Alligator sinensis Alligator_sinensis_CCG012491.1 N 0.000
Cmyd_10013609 Chelonia mydas Cmyd_10013609 N 0.000
ZNF710 Anolis carolinensis ENSACAG00000009870 N 0.000
ENSAMEG00000013487 Ailuropoda melanoleuca ENSAMEG00000013487 N 0.000
ENSAPLG00000010584 Anas platyrhynchos ENSAPLG00000010584 N 0.000
ZNF710 Bos taurus ENSBTAG00000019174 N 0.000
ENSBTAP00000025518-D1 Bos grunniens ENSBTAP00000025518-D1 N 0.000
ZNF710 Canis familiaris ENSCAFG00000012039 N 0.000
ZNF710 Callithrix jacchus ENSCJAG00000009435 N 0.000
ZNF710 Cavia porcellus ENSCPOG00000003532 N 0.000
ENSCSAG00000017122 Chlorocebus sabaeus ENSCSAG00000017122 N 0.000
ZNF710 Dasypus novemcinctus ENSDNOG00000048028 N 0.000
ZNF710 Equus caballus ENSECAG00000023093 N 0.000
ZNF710 Echinops telfairi ENSETEG00000007773 N 0.000
ENSFALG00000011037 Ficedula albicollis ENSFALG00000011037 N 0.000
ZNF710 Felis catus ENSFCAG00000005268 N 0.000
ZNF710 Homo sapiens ENSG00000140548 N 0.000
ENSGALG00000027434 Gallus gallus ENSGALG00000027434 N 0.000
ZNF710 Gorilla gorilla ENSGGOG00000004875 N 0.000
ENSLACG00000017953 Latimeria chalumnae ENSLACG00000017953 N 0.000
ZNF710 Loxodonta africana ENSLAFG00000010169 N 0.000
ENSLOCG00000014332 Lepisosteus oculatus ENSLOCG00000014332 N 0.000
ENSMEUG00000014197 Macropus eugenii ENSMEUG00000014197 N 0.000
ZNF710 Microcebus murinus ENSMICG00000011530 N 0.000
ENSMLUG00000002963 Myotis lucifugus ENSMLUG00000002963 N 0.000
ZNF710 Macaca mulatta ENSMMUG00000014831 N 0.000
ZNF710 Monodelphis domestica ENSMODG00000019518 N 0.000
ENSMPUG00000015742 Mustela putorius furo ENSMPUG00000015742 N 0.000
Zfp710 Mus musculus ENSMUSG00000048897 N 0.000
ENSNLEG00000011807 Nomascus leucogenys ENSNLEG00000011807 N 0.000
ENSOARG00000011959 Ovis aries ENSOARG00000011959 N 0.000
ZNF710 Oryctolagus cuniculus ENSOCUG00000015114 N 0.000
ZNF710 Otolemur garnettii ENSOGAG00000016446 N 0.000
ENSP00000268154 Macaca fascicularis ENSP00000268154 N 0.000
ENSPANG00000021467 Papio anubis ENSPANG00000021467 N 0.000
ZNF710 Pan troglodytes ENSPTRG00000007445 N 0.000
ZNF710 Pteropus vampyrus ENSPVAG00000011824 N 0.000
Zfp710 Rattus norvegicus ENSRNOG00000014278 N 0.000
ZNF710 Sorex araneus ENSSARG00000010704 N 0.000
ENSSHAG00000011785 Sarcophilus harrisii ENSSHAG00000011785 N 0.000
ZNF710 Sus scrofa ENSSSCG00000021361 N 0.000
ENSSTOG00000029208 Ictidomys tridecemlineatus ENSSTOG00000029208 N 0.000
ZNF710 Tursiops truncatus ENSTTRG00000000797 N 0.000
Myotis_brandtii_ZNF710_10004291 Myotis brandtii Myotis_brandtii_ZNF710_10004291 N 0.000
Ogr13398 Ophisaurus gracilis Ogr13398 N 0.000
Pvit_14028 Pogona vitticeps Pvit_14028 N 0.000
znf710 Xenopus tropicalis XB-GENE-981399 N 0.000