USF2 (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000105698 T034257_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
USF2
M04076_2.00		 Homo sapiens
NVCACGTGVCN
NGBCACGTGBN		 SELEX
Yin et al.(2017)
USF2_eDBD_HT-SELEX		 (Direct) (Direct)
USF2
M04077_2.00		 Homo sapiens
VNCAYGTGACN
NGTCACRTGNB		 SELEX
Yin et al.(2017)
USF2_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
USF2
M07785_2.00		 Homo sapiens
NGTCACGTGRBSVVV
BBBSVYCACGTGACN		 ChIP-seq
Gerstein et al.(2012)
GM12878_USF2_Stanford		 (Direct) (Direct)
USF2
M07786_2.00		 Homo sapiens
NVGTCACGTGRBSVVV
BBBSVYCACGTGACBN		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_USF2_Stanford		 (Direct) (Direct)
USF2
M07787_2.00		 Homo sapiens
RGTCACGTGVB
VBCACGTGACY		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_USF2_Stanford		 (Direct) (Direct)
USF2
M07788_2.00		 Homo sapiens
NGTCACGTGRBSV
BSVYCACGTGACN		 ChIP-seq
Gerstein et al.(2012)
HepG2_USF2_Stanford		 (Direct) (Direct)
USF2
M07789_2.00		 Homo sapiens
RGTCACGTGRBSV
BSVYCACGTGACY		 ChIP-seq
Gerstein et al.(2012)
K562_USF2_Stanford		 (Direct) (Direct)
USF2
M08050_2.00		 Homo sapiens
NNVYCACGTGACHNNN
NNNDGTCACGTGRBNN		 ChIP-seq
Mathelier et al.(2014)
MA0526.2		 (Direct) (Direct)
USF2
M08715_2.00		 Homo sapiens
NVGTCACGTGVBSVNNVNB
VNBNNBSVBCACGTGACBN		 Misc
Kulakovskiy et al.(2013)
USF2_HUMAN.H11MO.0.A		 (Direct) (Direct)
USF2
M09812_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$USF2_01		 (Direct) (Direct)
USF2
M09813_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$USF2_02		 (Direct) (Direct)
USF2
M09814_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$USF2_Q6_01		 (Direct) (Direct)
USF2
M09815_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$USF2_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Usf1
M01732_2.00 		Mus musculus
NRYCACGTGNN
NNCACGTGRYN		 PBM
Weirauch et al.(2014)
pTH4376 		0.607 1.000
Usf2
M01752_2.00 		Mus musculus
NNCACGTGAN
NTCACGTGNN		 PBM
Weirauch et al.(2014)
pTH5265 		0.607 1.000
USF1
M02792_2.00 		Homo sapiens
RNCACGTGRY
RYCACGTGNY		 SELEX
Jolma et al.(2013)
USF1_1 		0.607 1.000
USF1
M04146_2.00 		Homo sapiens
NVCACGTGVCN
NGBCACGTGBN		 SELEX
Yin et al.(2017)
USF1_FL_HT-SELEX 		0.607 1.000
USF1
M08056_2.00 		Homo sapiens
RGTCACRTGVB
VBCAYGTGACY		 ChIP-seq
Mathelier et al.(2014)
MA0093.2 		0.607 1.000
USF1
M07807_2.00 		Homo sapiens
VGTCACGTGRBSVVV
BBBSVYCACGTGACB		 ChIP-seq
Gerstein et al.(2012)
A549_USF1_HudsonAlpha 		0.607 1.000
USF1
M07808_2.00 		Homo sapiens
VVGTCACGTGVBSVS
SBSVBCACGTGACBB		 ChIP-seq
Gerstein et al.(2012)
GM12878_USF1_HudsonAlpha 		0.607 1.000
USF1
M07809_2.00 		Homo sapiens
RGTCACGTGVBSVNN
NNBSVBCACGTGACY		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_USF1_HudsonAlpha 		0.607 1.000
USF1
M07810_2.00 		Homo sapiens
VGTCACGTGRB
VYCACGTGACB		 ChIP-seq
Gerstein et al.(2012)
HepG2_USF1_HudsonAlpha 		0.607 1.000
Usf2
M08777_2.00 		Mus musculus
NVGTCACGTGVBSVNNVNB
VNBNNBSVBCACGTGACBN		 Misc
Kulakovskiy et al.(2013)
USF2_MOUSE.H11MO.0.A 		0.871 0.981
USF1
M07811_2.00 		Homo sapiens
NVGTCACGTGVSSV
BSSBCACGTGACBN		 ChIP-seq
Gerstein et al.(2012)
K562_USF1_HudsonAlpha 		0.607 1.000
Usf2
M09479_2.00 		Mus musculus
NNCAYGTGVY
RBCACRTGNN		 Misc
Heinz et al.(2010)
C2C12-Usf2_GSE36030 		0.871 0.981
USF1
M08733_2.00 		Homo sapiens
VGTCACGTGVBS
SVBCACGTGACB		 Misc
Kulakovskiy et al.(2013)
USF1_HUMAN.H11MO.0.A 		0.607 1.000
Usf1
M08756_2.00 		Mus musculus
NNGTCACGTGVBS
SVBCACGTGACNN		 Misc
Kulakovskiy et al.(2013)
USF1_MOUSE.H11MO.0.A 		0.607 1.000
USF1
M09460_2.00 		Homo sapiens
YCACGTGRBN
NVYCACGTGR		 Misc
Heinz et al.(2010)
GM12878-Usf1_GSE32465 		0.607 1.000
USF1
M09867_2.00 		Homo sapiens
NNRYCACGTGRYNN
NNRYCACGTGRYNN		 Transfac
Matys et al.(2006)
V$USF_01 		0.607 1.000
USF1
M09868_2.00 		Homo sapiens
NNRNCAYRTGNYNN
NNRNCAYRTGNYNN		 Transfac
Matys et al.(2006)
V$USF_02 		0.607 1.000
USF1
M09869_2.00 		Homo sapiens
HCACGTGH
DCACGTGD		 Transfac
Matys et al.(2006)
V$USF_C 		0.607 1.000
USF1
M04147_2.00 		Homo sapiens
VHCAYGTGAYN
NRTCACRTGDB		 SELEX
Yin et al.(2017)
USF1_FL_Methyl-HT-SELEX 		0.607 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000222305 bHLH 236 291
ENSP00000340633 bHLH 169 224
ENSP00000368429 bHLH 105 160
ENSP00000469364 bHLH 92 198
ENSP00000470081 bHLH 41 96
ENSP00000471099 bHLH 236 283
ENSP00000471511 bHLH 234 289
ENSP00000471775 bHLH 114 143

Links

Other bHLH family TFs
Other Homo sapiens TFs

62 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
29938.m000611 Ricinus communis 29938.m000611 I
Bo2g072950 Brassica oleracea Bo2g072950 I
Bo5g038890 Brassica oleracea Bo5g038890 I
Bo6g113060 Brassica oleracea Bo6g113060 I
Bostr.10273s0198 Boechera stricta Bostr.10273s0198 I
Bostr.12659s0135 Boechera stricta Bostr.12659s0135 I
Bra007974 Brassica rapa Bra007974 I
Bra012345 Brassica rapa Bra012345 I
Bra016133 Brassica rapa Bra016133 I
Bra024539 Brassica rapa Bra024539 I
Cagra.0114s0023 Capsella grandiflora Cagra.0114s0023 I
Cagra.2418s0007 Capsella grandiflora Cagra.2418s0007 I
Carubv10011955m.g Capsella rubella Carubv10011955m.g I
Carubv10022408m.g Capsella rubella Carubv10022408m.g I
cassava8476.m1 Manihot esculenta cassava8476.m1 I
Ca_15055 Cicer arietinum Ca_15055 I
chr2.CM0018.340.nd Lotus japonicus chr2.CM0018.340.nd I
Ciclev10023345m.g Citrus clementina Ciclev10023345m.g I
Cla012182 Citrullus lanatus Cla012182 I
Cucsa.088640 Cucumis sativus Cucsa.088640 N
ERF019 Arabidopsis thaliana AT1G22810 D
ERF020 Arabidopsis thaliana AT1G71520 I
Eucgr.F02967 Eucalyptus grandis Eucgr.F02967 I
evm.TU.supercontig_21.63 Carica papaya evm.TU.supercontig_21.63 I
fgenesh2_kg.2__1411__AT1G71520.1 Arabidopsis lyrata fgenesh2_kg.2__1411__AT1G71520.1 I
GLYMA11G01700 Glycine max GLYMA11G01700 I
Lus10006179.g Linum usitatissimum Lus10006179.g I
Lus10009468.g Linum usitatissimum Lus10009468.g I
Lus10041044.g Linum usitatissimum Lus10041044.g I
mgf010891m Mimulus guttatus mgf010891m I
MTR_5g008790 Medicago truncatula MTR_5g008790 I
orange1.1g045327m.g Citrus sinensis orange1.1g045327m.g I
POPTR_0013s10420 Populus trichocarpa POPTR_0013s10420 I
POPTR_0019s10220 Populus trichocarpa POPTR_0019s10220 I
SapurV1A.2173s0020 Salix purpurea SapurV1A.2173s0020 I
SapurV1A.3847s0010 Salix purpurea SapurV1A.3847s0010 I
SapurV1A.4200s0010 Salix purpurea SapurV1A.4200s0010 I
scaffold_102587.1 Arabidopsis lyrata scaffold_102587.1 I
TCM_036224 Theobroma cacao TCM_036224 I
Thhalv10009842m.g Eutrema salsugineum Thhalv10009842m.g I
Thhalv10019510m.g Eutrema salsugineum Thhalv10019510m.g I