CDX1 (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000113722 T209807_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CDX1
M03115_2.00		 Homo sapiens
NTTTATKRB
VYMATAAAN		 SELEX
Jolma et al.(2013)
CDX1_1		 (Direct) (Direct)
CDX1
M05018_2.00		 Homo sapiens
VKTTTATKRCN
NGYMATAAAMB		 SELEX
Yin et al.(2017)
CDX1_eDBD_HT-SELEX		 (Direct) (Direct)
CDX1
M05019_2.00		 Homo sapiens
NGTCGTAAAWB
VWTTTACGACN		 SELEX
Yin et al.(2017)
CDX1_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
CDX1
M09140_2.00		 Homo sapiens
HCWTAAAD
HTTTAWGD		 Misc
Kulakovskiy et al.(2013)
CDX1_HUMAN.H11MO.0.C		 (Direct) (Direct)
CDX1
M10670_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX1_Q4		 (Direct) (Direct)
CDX1
M10671_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX1_Q5		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Cdx1
M00427_2.00 		Mus musculus
NWWATDRNN
NNYHATWWN		 PBM
Berger et al.(2008)
Cdx1_2245 		0.867 1.000
Cdx1
M09186_2.00 		Mus musculus
HCWTAAAD
HTTTAWGD		 Misc
Kulakovskiy et al.(2013)
CDX1_MOUSE.H11MO.0.C 		0.867 1.000
CDX1
M10761_2.00 		Gallus gallus
BDBWAAK
MTTWVHV		 Transfac
Matys et al.(2006)
V$CDXA_01 		0.855 0.965
CDX1
M10762_2.00 		Gallus gallus
WWWWMYR
YRKWAWW		 Transfac
Matys et al.(2006)
V$CDXA_02 		0.855 0.965
CDX2
M03196_2.00 		Homo sapiens
KTTTATKRB
VYMATAAAM		 SELEX
Jolma et al.(2013)
CDX2_1 		0.855 0.947
CDX2
M05248_2.00 		Homo sapiens
NDTWAYRRYN
NRYYRTWAHN		 SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_1 		0.855 0.947
CDX2
M05249_2.00 		Homo sapiens
NDWWATKRB
VYMATWWHN		 SELEX
Yin et al.(2017)
CDX2_eDBD_HT-SELEX_2 		0.855 0.947
CDX2
M08131_2.00 		Homo sapiens
YTTTATKRCHB
VDGYMATAAAR		 ChIP-seq
Mathelier et al.(2014)
MA0465.1 		0.855 0.947
CDX2
M09152_2.00 		Homo sapiens
DTTBATKGCHNB
VNDGCMATVAAH		 Misc
Kulakovskiy et al.(2013)
CDX2_HUMAN.H11MO.0.A 		0.855 0.947
CDX2
M10723_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5_01 		0.855 0.947
CDX2
M10724_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5_02 		0.855 0.947
CDX2
M10725_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q5 		0.855 0.947
CDX2
M10726_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CDX2_Q6 		0.855 0.947
CDX2
M05250_2.00 		Homo sapiens
NRTCGTAWHBNN
NNVDWTACGAYN		 SELEX
Yin et al.(2017)
CDX2_eDBD_Methyl-HT-SELEX 		0.855 0.947
Cdx2
M00447_2.00 		Mus musculus
NWWAYDRNN
NNYHRTWWN		 PBM
Berger et al.(2008)
Cdx2_4272 		0.850 0.947
Cdx2
M09193_2.00 		Mus musculus
BTTTATKRCYBY
RVRGYMATAAAV		 Misc
Kulakovskiy et al.(2013)
CDX2_MOUSE.H11MO.0.A 		0.850 0.947
Cdx2
M09572_2.00 		Mus musculus
NTTTTATKRC
GYMATAAAAN		 Misc
Heinz et al.(2010)
mES-Cdx2_GSE14586 		0.850 0.947
cad
M03780_2.00 		Drosophila melanogaster
NKTTTATKRCHB
VDGYMATAAAMN		 SELEX
Nitta et al.(2015)
cad_1 		0.840 0.860
cad
M03781_2.00 		Drosophila melanogaster
NDTTTATKRCHN
NDGYMATAAAHN		 SELEX
Nitta et al.(2015)
cad_2 		0.840 0.860
cad
M03782_2.00 		Drosophila melanogaster
NDTTTATKRCNB
VNGYMATAAAHN		 SELEX
Nitta et al.(2015)
cad_3 		0.840 0.860
cad
M03783_2.00 		Drosophila melanogaster
NNTTTAYGRYNN
NNRYCRTAAANN		 SELEX
Nitta et al.(2015)
cad_4 		0.840 0.860
cad
M06223_2.00 		Drosophila melanogaster
HTTWATTR
YAATWAAD		 B1H
Zhu et al.(2011)
Cad_Cell_FBgn0000251 		0.840 0.860
cad
M06224_2.00 		Drosophila melanogaster
RBYVDAAMV
BKTTHBRVY		 B1H
Zhu et al.(2011)
cad_FlyReg_FBgn0000251 		0.840 0.860
cad
M06225_2.00 		Drosophila melanogaster
NTTWATKR
YMATWAAN		 B1H
Zhu et al.(2011)
Cad_SOLEXA_FBgn0000251 		0.840 0.860
cad
M08420_2.00 		Drosophila melanogaster
DTTTTATKRYY
RRYMATAAAAH		 ChIP-chip
Mathelier et al.(2014)
MA0216.2 		0.840 0.860
cad
M09580_2.00 		Drosophila melanogaster
DTTTAYGRYN
NRYCRTAAAH		 Misc
Heinz et al.(2010)
Drosophila-Embryos_modEncode 		0.840 0.860
cad
M09674_2.00 		Drosophila melanogaster
HTTTATKRBY
RVYMATAAAD		 Misc
Kulakovskiy et al.(2009)
cad 		0.840 0.860
cad
M10783_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$CAD_Q6 		0.840 0.860
Q70LF3_ARTSF
M02211_2.00 		Artemia franciscana
BTAATTAB
VTAATTAV		 PBM
Weirauch et al.(2014)
pTH5553 		0.834 0.895
Cdx4
M09197_2.00 		Mus musculus
WGATTTATDRBH
DVYHATAAATCW		 Misc
Kulakovskiy et al.(2013)
CDX4_MOUSE.H11MO.0.A 		0.831 0.912
CDX4
M05129_2.00 		Homo sapiens
VKTTTATKRCH
DGYMATAAAMB		 SELEX
Yin et al.(2017)
CDX4_FL_HT-SELEX 		0.831 0.895
CDX4
M05130_2.00 		Homo sapiens
BGTCGTAAAHN
NDTTTACGACV		 SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_1 		0.831 0.895
CDX4
M05131_2.00 		Homo sapiens
VKTTTATKGCN
NGCMATAAAMB		 SELEX
Yin et al.(2017)
CDX4_FL_Methyl-HT-SELEX_2 		0.831 0.895
pal-1
M02183_2.00 		Caenorhabditis elegans
GYAATWAA
TTWATTRC		 PBM
Weirauch et al.(2014)
pTH6016 		0.650 0.719
Q9GP48_9TURB
M02217_2.00 		Discocelis tigrina
DTAATTAB
VTAATTAH		 PBM
Weirauch et al.(2014)
pTH6515 		0.641 0.737
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.613 0.579
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000231656 Homeodomain 155 211
ENSP00000477928 Homeodomain 44 100

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

318 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL013896 Aedes aegypti AAEL013896 I 0.000
AAH84196 Xenopus laevis AAH84196 I 0.000
AALB009485 Anopheles albimanus AALB009485 I 0.000
AARA004719 Anopheles arabiensis AARA004719 I 0.000
AATE010695 Anopheles atroparvus AATE010695 I 0.000
ACHR000067 Anopheles christyi ACHR000067 I 0.000
ACOM037505 Anopheles coluzzii ACOM037505 I 0.000
ACUA025512 Anopheles culicifacies ACUA025512 I 0.000
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.000
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.000
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.000
ADAC007516 Anopheles darlingi ADAC007516 I 0.000
ADIR002761 Anopheles dirus ADIR002761 I 0.000
AEPI002385 Anopheles epiroticus AEPI002385 I 0.000
AFAF011208 Anopheles farauti AFAF011208 I 0.000
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.000
AFUN009864 Anopheles funestus AFUN009864 I 0.000
AGAP002902 Anopheles gambiae AGAP002902 I 0.000
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.000
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.000
AMAM019778 Anopheles maculatus AMAM019778 I 0.000
AMEM015931 Anopheles merus AMEM015931 I 0.000
AMIN000723 Anopheles minimus AMIN000723 I 0.000
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.000
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.000
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.000
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.000
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.000
CapteG179368 Capitella teleta CapteG179368 I 0.000
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.000
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.000
CLEC002594 Cimex lectularius CLEC002594 I 0.000
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.000
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.000
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.000
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.000
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.000
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.000
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.000
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.000
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.000
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.000
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.000
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.000
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.000
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.000
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.000
ENSLOCG00000006749 Lepisosteus oculatus ENSLOCG00000006749 N 0.000
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.000
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.000
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.000
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.000
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.000
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.000
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.000
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.000
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.000
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.000
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.000
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.000
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.000
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.000
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.000
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.000
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.000
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.000
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.000
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.000
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.000
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.000
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.000
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.000
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.000
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.000
GB50071 Apis mellifera GB50071 I 0.000
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.000
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.000
GE10952 Drosophila yakuba FBgn0228782 I 0.000
GF22974 Drosophila ananassae FBgn0099968 I 0.000
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.000
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.000
GG11819 Drosophila erecta FBgn0104114 I 0.000
GH18642 Drosophila grimshawi FBgn0126109 I 0.000
GI23400 Drosophila mojavensis FBgn0146126 I 0.000
GJ23092 Drosophila virilis FBgn0210194 I 0.000
GK11724 Drosophila willistoni FBgn0213735 I 0.000
GL23637 Drosophila persimilis FBgn0161227 I 0.000
GM16436 Drosophila sechellia FBgn0171351 I 0.000
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.000
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.000
HMEL002203 Heliconius melpomene HMEL002203 I 0.000
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.000
ISCW018468 Ixodes scapularis ISCW018468 I 0.000
KGM_12572 Danaus plexippus KGM_12572 I 0.000
L798_13939 Zootermopsis nevadensis L798_13939 I 0.000
LCUP007928 Lucilia cuprina LCUP007928 I 0.000
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.000
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.000
LotgiG131078 Lottia gigantea LotgiG131078 I 0.000
MCINX014520 Melitaea cinxia MCINX014520 I 0.000
MDOA012885 Musca domestica MDOA012885 I 0.000
Med Drosophila melanogaster FBgn0011655 D 0.000
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.000
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.000
NV12984 Nasonia vitripennis NV12984 I 0.000
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.000
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.000
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.000
PHUM002670 Pediculus humanus PHUM002670 I 0.000
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.000
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.000
RPRC010188 Rhodnius prolixus RPRC010188 I 0.000
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.000
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.000
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.000
SINV15516 Solenopsis invicta SINV15516 I 0.000
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.000
SMAD4 Bos taurus ENSBTAG00000006919 I 0.000
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.000
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.000
smad4 Ciona intestinalis ENSCING00000005559 I 0.000
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.000
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.000
SMAD4 Danio rerio ENSDARG00000012649 I 0.000
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.000
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.000
SMAD4 Equus caballus ENSECAG00000017857 I 0.000
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.000
SMAD4 Felis catus ENSFCAG00000005257 I 0.000
SMAD4 Homo sapiens ENSG00000141646 D 0.000
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.000
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.000
SMAD4 Microcebus murinus ENSMICG00000017525 I 0.000
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.000
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.000
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.000
Smad4 Mus musculus ENSMUSG00000024515 D 0.000
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.000
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.000
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.000
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.000
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.000
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.000
SMAD4 Pteropus vampyrus ENSPVAG00000004261 I 0.000
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.000
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.000
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.000
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.000
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.000
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.000
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.000
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.000
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.000
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.000
smad4a Danio rerio ENSDARG00000075226 I 0.000
smad4a Oryzias latipes ENSORLG00000005020 I 0.000
SMAR013850 Strigamia maritima SMAR013850 I 0.000
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.000
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.000
TC010848 Tribolium castaneum TC010848 I 0.000
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.000
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.000
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.000