Smad4 (Rattus norvegicus)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSRNOG00000051965 T324934_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		1.000 1.000
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		1.000 1.000
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		1.000 1.000
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		1.000 1.000
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		1.000 1.000
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		1.000 1.000
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		1.000 1.000
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.961 0.961
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.961 0.961
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000070425 SMAD 36 137
ENSRNOP00000074882 SMAD 36 137

Links

Other SMAD family TFs
Other Rattus norvegicus TFs

218 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SMAD4 Anolis carolinensis ENSACAG00000010186 I 1.000
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 1.000
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 1.000
SMAD4 Bos taurus ENSBTAG00000006919 I 1.000
SMAD4 Canis familiaris ENSCAFG00000000164 I 1.000
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 1.000
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 1.000
SMAD4 Cavia porcellus ENSCPOG00000006470 I 1.000
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 1.000
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 1.000
Smad4 Dipodomys ordii ENSDORG00000009089 I 1.000
SMAD4 Equus caballus ENSECAG00000017857 I 1.000
SMAD4 Echinops telfairi ENSETEG00000007750 I 1.000
SMAD4 Felis catus ENSFCAG00000005257 I 1.000
SMAD4 Homo sapiens ENSG00000141646 D 1.000
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 1.000
SMAD4 Loxodonta africana ENSLAFG00000012595 I 1.000
SMAD4 Microcebus murinus ENSMICG00000017525 I 1.000
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 1.000
SMAD4 Macaca mulatta ENSMMUG00000018334 I 1.000
SMAD4 Monodelphis domestica ENSMODG00000010995 I 1.000
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 1.000
Smad4 Mus musculus ENSMUSG00000024515 D 1.000
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 1.000
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 1.000
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 1.000
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 1.000
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 1.000
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 1.000
SMAD4 Ochotona princeps ENSOPRG00000013601 I 1.000
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 1.000
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 1.000
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 1.000
SMAD4 Pan troglodytes ENSPTRG00000010028 I 1.000
SMAD4 Pteropus vampyrus ENSPVAG00000004261 I 1.000
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 1.000
SMAD4 Sus scrofa ENSSSCG00000004524 I 1.000
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 1.000
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 1.000
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 1.000
SMAD4 Vicugna pacos ENSVPAG00000006757 I 1.000
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 1.000
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 1.000
Brh_R010414 Buceros rhinoceros Brh_R010414 I 1.000
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 1.000
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 1.000
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 1.000
Gfo_R011803 Geospiza fortis Gfo_R011803 I 1.000
Gfo_R016223 Geospiza fortis Gfo_R016223 I 1.000
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 1.000
Ogr14199 Ophisaurus gracilis Ogr14199 I 1.000
Pvit_01119 Pogona vitticeps Pvit_01119 I 1.000
AAH84196 Xenopus laevis AAH84196 I 1.000
smad4.1 Xenopus tropicalis XB-GENE-485691 I 1.000
smad4.1.L Xenopus laevis XB-GENE-865543 I 1.000
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.990
smad4a Danio rerio ENSDARG00000075226 I 0.990
smad4a Oryzias latipes ENSORLG00000005020 I 0.990
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.990
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.990
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.990
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.990
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.990
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.990
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.990
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.980
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.980
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.980
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.980
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.980
ISCW018468 Ixodes scapularis ISCW018468 I 0.980
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.980
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.980
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.980
AAEL013896 Aedes aegypti AAEL013896 I 0.971
SMAD4 Danio rerio ENSDARG00000012649 I 0.971
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.971
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.971
L798_13939 Zootermopsis nevadensis L798_13939 I 0.971
PHUM002670 Pediculus humanus PHUM002670 I 0.971
SMAR013850 Strigamia maritima SMAR013850 I 0.971
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.971
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.961
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.961
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.961
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.961
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.961
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.961
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.961
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.961
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.961
Med Drosophila melanogaster FBgn0011655 D 0.961
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.961
GF22974 Drosophila ananassae FBgn0099968 I 0.961
GG11819 Drosophila erecta FBgn0104114 I 0.961
GH18642 Drosophila grimshawi FBgn0126109 I 0.961
GI23400 Drosophila mojavensis FBgn0146126 I 0.961
GL23637 Drosophila persimilis FBgn0161227 I 0.961
GM16436 Drosophila sechellia FBgn0171351 I 0.961
GJ23092 Drosophila virilis FBgn0210194 I 0.961
GK11724 Drosophila willistoni FBgn0213735 I 0.961
GE10952 Drosophila yakuba FBgn0228782 I 0.961
GB50071 Apis mellifera GB50071 I 0.961
NV12984 Nasonia vitripennis NV12984 I 0.961
SINV15516 Solenopsis invicta SINV15516 I 0.961
TC010848 Tribolium castaneum TC010848 I 0.961
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.961
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.961
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.961
LCUP007928 Lucilia cuprina LCUP007928 I 0.961
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.961
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.961
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.961
MDOA012885 Musca domestica MDOA012885 I 0.961
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.951
AGAP002902 Anopheles gambiae AGAP002902 I 0.951
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.951
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.951
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.951
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.951
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.951
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.951
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.951
HMEL002203 Heliconius melpomene HMEL002203 I 0.951
KGM_12572 Danaus plexippus KGM_12572 I 0.951
MCINX014520 Melitaea cinxia MCINX014520 I 0.951
RPRC010188 Rhodnius prolixus RPRC010188 I 0.951
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.951
CLEC002594 Cimex lectularius CLEC002594 I 0.951
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.951
AARA004719 Anopheles arabiensis AARA004719 I 0.951
AATE010695 Anopheles atroparvus AATE010695 I 0.951
ACHR000067 Anopheles christyi ACHR000067 I 0.951
ACOM037505 Anopheles coluzzii ACOM037505 I 0.951
ACUA025512 Anopheles culicifacies ACUA025512 I 0.951
ADIR002761 Anopheles dirus ADIR002761 I 0.951
AEPI002385 Anopheles epiroticus AEPI002385 I 0.951
AFAF011208 Anopheles farauti AFAF011208 I 0.951
AFUN009864 Anopheles funestus AFUN009864 I 0.951
AMAM019778 Anopheles maculatus AMAM019778 I 0.951
AMEM015931 Anopheles merus AMEM015931 I 0.951
AMIN000723 Anopheles minimus AMIN000723 I 0.951
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.951
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.951
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.951
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.941
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.941
LotgiG131078 Lottia gigantea LotgiG131078 I 0.941
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.941
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.941
ADAC007516 Anopheles darlingi ADAC007516 I 0.931
CapteG179368 Capitella teleta CapteG179368 I 0.931
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.931
AALB009485 Anopheles albimanus AALB009485 I 0.931
smad4 Ciona intestinalis ENSCING00000005559 I 0.922
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.922
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.912
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.912
CGI_10018464 Crassostrea gigas CGI_10018464 I 0.911
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.902
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.902
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.902
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.902
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.892
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.892
HelroG88197 Helobdella robusta HelroG88197 I 0.882
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.882
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.882
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.873
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.873
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.863
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.863
ML02191a Mnemiopsis leidyi ML02191a I 0.863
Aan_R014474 Calypte anna Aan_R014474 I 0.845
ACEP19585 Atta cephalotes ACEP19585 I 0.843
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.833
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.833
EFV62078 Trichinella spiralis EFV62078 I 0.824
D917_09719 Trichinella nativa D917_09719 I 0.824
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.821
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.814
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.804
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.804
D915_03789 Fasciola hepatica D915_03789 I 0.804
T265_11013 Opisthorchis viverrini T265_11013 I 0.804
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.794
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.794
Bm3575 Brugia malayi Bm3575 I 0.784
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.784
HelroG76435 Helobdella robusta HelroG76435 I 0.784
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.784
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.775
ASU_13433 Ascaris suum ASU_13433 I 0.775
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.775
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.775
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.775
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.775
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.775
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.767
LOAG_08923 Loa loa LOAG_08923 I 0.765
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.765
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.765
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.765
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.765
D918_00298 Trichuris suis D918_00298 I 0.760
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.755
Sakowv30001112m.g Saccoglossus kowalevskii Sakowv30001112m.g I 0.746
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.745
Smp_033950 Schistosoma mansoni Smp_033950 I 0.725
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.725
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.716
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.706
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.706
OESDEN_03018 Oesophagostomum dentatum OESDEN_03018 I 0.706
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.706
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.706
HPBE_0001599301 Heligmosomoides bakeri HPBE_0001599301 I 0.702