SMU15015494 (Schmidtea mediterranea)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF03165 (MH1) IPR003619 SMU15015494 T325412_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.824 0.824
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.824 0.824
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.814 0.814
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.814 0.814
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.814 0.814
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.814 0.814
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.814 0.814
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.814 0.814
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.814 0.814
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
SMU15015494 SMAD 38 139

Links

Other SMAD family TFs
Other Schmidtea mediterranea TFs

214 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.853
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.843
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.843
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.833
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.833
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.833
ISCW018468 Ixodes scapularis ISCW018468 I 0.833
LotgiG131078 Lottia gigantea LotgiG131078 I 0.833
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.833
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.833
AAEL013896 Aedes aegypti AAEL013896 I 0.824
AGAP002902 Anopheles gambiae AGAP002902 I 0.824
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.824
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.824
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.824
SMAD4 Homo sapiens ENSG00000141646 D 0.824
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.824
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.824
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.824
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.824
Med Drosophila melanogaster FBgn0011655 D 0.824
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.824
GF22974 Drosophila ananassae FBgn0099968 I 0.824
GG11819 Drosophila erecta FBgn0104114 I 0.824
GH18642 Drosophila grimshawi FBgn0126109 I 0.824
GI23400 Drosophila mojavensis FBgn0146126 I 0.824
GL23637 Drosophila persimilis FBgn0161227 I 0.824
GM16436 Drosophila sechellia FBgn0171351 I 0.824
GJ23092 Drosophila virilis FBgn0210194 I 0.824
GK11724 Drosophila willistoni FBgn0213735 I 0.824
GE10952 Drosophila yakuba FBgn0228782 I 0.824
HMEL002203 Heliconius melpomene HMEL002203 I 0.824
KGM_12572 Danaus plexippus KGM_12572 I 0.824
L798_13939 Zootermopsis nevadensis L798_13939 I 0.824
MCINX014520 Melitaea cinxia MCINX014520 I 0.824
PHUM002670 Pediculus humanus PHUM002670 I 0.824
SMAR013850 Strigamia maritima SMAR013850 I 0.824
TC010848 Tribolium castaneum TC010848 I 0.824
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.824
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.824
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.824
LCUP007928 Lucilia cuprina LCUP007928 I 0.824
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.824
AARA004719 Anopheles arabiensis AARA004719 I 0.824
AATE010695 Anopheles atroparvus AATE010695 I 0.824
ACHR000067 Anopheles christyi ACHR000067 I 0.824
ACOM037505 Anopheles coluzzii ACOM037505 I 0.824
ACUA025512 Anopheles culicifacies ACUA025512 I 0.824
ADIR002761 Anopheles dirus ADIR002761 I 0.824
AEPI002385 Anopheles epiroticus AEPI002385 I 0.824
AFAF011208 Anopheles farauti AFAF011208 I 0.824
AFUN009864 Anopheles funestus AFUN009864 I 0.824
AMAM019778 Anopheles maculatus AMAM019778 I 0.824
AMEM015931 Anopheles merus AMEM015931 I 0.824
AMIN000723 Anopheles minimus AMIN000723 I 0.824
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.824
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.824
MDOA012885 Musca domestica MDOA012885 I 0.824
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.822
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.814
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.814
ADAC007516 Anopheles darlingi ADAC007516 I 0.814
CapteG179368 Capitella teleta CapteG179368 I 0.814
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.814
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.814
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.814
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.814
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.814
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.814
SMAD4 Bos taurus ENSBTAG00000006919 I 0.814
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.814
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.814
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.814
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.814
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.814
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.814
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.814
SMAD4 Equus caballus ENSECAG00000017857 I 0.814
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.814
SMAD4 Felis catus ENSFCAG00000005257 I 0.814
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.814
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.814
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.814
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.814
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.814
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.814
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.814
Smad4 Mus musculus ENSMUSG00000024515 D 0.814
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.814
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.814
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.814
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.814
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.814
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.814
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.814
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.814
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.814
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.814
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.814
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.814
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.814
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.814
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.814
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.814
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.814
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.814
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.814
GB50071 Apis mellifera GB50071 I 0.814
HelroG88197 Helobdella robusta HelroG88197 I 0.814
NV12984 Nasonia vitripennis NV12984 I 0.814
RPRC010188 Rhodnius prolixus RPRC010188 I 0.814
SINV15516 Solenopsis invicta SINV15516 I 0.814
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.814
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.814
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.814
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.814
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.814
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.814
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.814
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.814
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.814
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.814
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.814
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.814
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.814
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.814
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.814
AAH84196 Xenopus laevis AAH84196 I 0.814
CLEC002594 Cimex lectularius CLEC002594 I 0.814
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.814
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.814
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.814
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.814
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.814
AALB009485 Anopheles albimanus AALB009485 I 0.814
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.804
smad4a Danio rerio ENSDARG00000075226 I 0.804
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.804
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.804
smad4a Oryzias latipes ENSORLG00000005020 I 0.804
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.804
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.804
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.804
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.804
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.804
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.804
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.804
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.804
ML02191a Mnemiopsis leidyi ML02191a I 0.804
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.804
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.804
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.794
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.794
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.794
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.794
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.794
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.794
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.794
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.794
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.794
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.794
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.794
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.794
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.784
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.784
EFV62078 Trichinella spiralis EFV62078 I 0.784
SMAD4 Danio rerio ENSDARG00000012649 I 0.784
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.784
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.784
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.784
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.784
D915_03789 Fasciola hepatica D915_03789 I 0.784
D917_09719 Trichinella nativa D917_09719 I 0.784
smad4 Ciona intestinalis ENSCING00000005559 I 0.775
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.775
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.775
T265_11013 Opisthorchis viverrini T265_11013 I 0.765
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.755
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.755
HelroG76435 Helobdella robusta HelroG76435 I 0.745
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.745
Aan_R014474 Calypte anna Aan_R014474 I 0.741
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.735
Minc15475 Meloidogyne incognita Minc15475 N 0.735
ASU_13433 Ascaris suum ASU_13433 I 0.735
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.735
genemark-nMf.1.1.scaf08549-processed-gene-0.3 Meloidogyne floridensis genemark-nMf.1.1.scaf08549-processed-gene-0.3 N 0.735
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.735
L889_g28104 Steinernema feltiae L889_g28104 I 0.735
MhA1_Contig1148.frz3.fgene1 Meloidogyne hapla MhA1_Contig1148.frz3.fgene1 N 0.735
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.735
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.735
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.735
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.735
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.735
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.735
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.732
LOAG_08923 Loa loa LOAG_08923 I 0.725
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.725
L596_g15 Steinernema carpocapsae L596_g15 I 0.725
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.716
Bm3575 Brugia malayi Bm3575 I 0.716
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.716
ECANG7_08262 Echinococcus canadensis ECANG7_08262 N 0.716
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.716
L893_g344 Steinernema glaseri L893_g344 I 0.716
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.706
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.706
EmuJ_000217400 Echinococcus multilocularis EmuJ_000217400 N 0.706
L898_g17086 Steinernema monticolum L898_g17086 I 0.706
MCOS_0000775001 Mesocestoides corti MCOS_0000775001 N 0.706
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.706
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.706
TsM_000635600 Taenia solium TsM_000635600 N 0.706