HelroG76435 (Helobdella robusta)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 HelroG76435 T325115_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.804 0.804
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.804 0.804
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.784 0.784
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.784 0.784
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.784 0.784
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.784 0.784
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.784 0.784
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.784 0.784
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.784 0.784
sma-4
M02484_2.00 		Caenorhabditis elegans
NNCCAGACANN
NNTGTCTGGNN		 PBM
Weirauch et al.(2014)
pTH8996 		0.706 0.706
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HelroP76435 SMAD 33 134

Links

Other SMAD family TFs
Other Helobdella robusta TFs

225 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ADAC007516 Anopheles darlingi ADAC007516 I 0.843
AALB009485 Anopheles albimanus AALB009485 I 0.843
AGAP002902 Anopheles gambiae AGAP002902 I 0.833
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.833
CapteG179368 Capitella teleta CapteG179368 I 0.833
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.833
HMEL002203 Heliconius melpomene HMEL002203 I 0.833
KGM_12572 Danaus plexippus KGM_12572 I 0.833
MCINX014520 Melitaea cinxia MCINX014520 I 0.833
AARA004719 Anopheles arabiensis AARA004719 I 0.833
AATE010695 Anopheles atroparvus AATE010695 I 0.833
ACHR000067 Anopheles christyi ACHR000067 I 0.833
ACOM037505 Anopheles coluzzii ACOM037505 I 0.833
ACUA025512 Anopheles culicifacies ACUA025512 I 0.833
ADIR002761 Anopheles dirus ADIR002761 I 0.833
AEPI002385 Anopheles epiroticus AEPI002385 I 0.833
AFAF011208 Anopheles farauti AFAF011208 I 0.833
AFUN009864 Anopheles funestus AFUN009864 I 0.833
AMAM019778 Anopheles maculatus AMAM019778 I 0.833
AMEM015931 Anopheles merus AMEM015931 I 0.833
AMIN000723 Anopheles minimus AMIN000723 I 0.833
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.833
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.833
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.824
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.824
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.824
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.824
GB50071 Apis mellifera GB50071 I 0.824
LotgiG131078 Lottia gigantea LotgiG131078 I 0.824
NV12984 Nasonia vitripennis NV12984 I 0.824
SINV15516 Solenopsis invicta SINV15516 I 0.824
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.824
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.824
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.824
AAEL013896 Aedes aegypti AAEL013896 I 0.814
HelroG88197 Helobdella robusta HelroG88197 I 0.814
L798_13939 Zootermopsis nevadensis L798_13939 I 0.814
PHUM002670 Pediculus humanus PHUM002670 I 0.814
RPRC010188 Rhodnius prolixus RPRC010188 I 0.814
SMAR013850 Strigamia maritima SMAR013850 I 0.814
CLEC002594 Cimex lectularius CLEC002594 I 0.814
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.814
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.814
SMAD4 Danio rerio ENSDARG00000012649 I 0.804
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.804
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.804
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.804
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.804
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.804
Med Drosophila melanogaster FBgn0011655 D 0.804
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.804
GF22974 Drosophila ananassae FBgn0099968 I 0.804
GG11819 Drosophila erecta FBgn0104114 I 0.804
GH18642 Drosophila grimshawi FBgn0126109 I 0.804
GI23400 Drosophila mojavensis FBgn0146126 I 0.804
GL23637 Drosophila persimilis FBgn0161227 I 0.804
GM16436 Drosophila sechellia FBgn0171351 I 0.804
GJ23092 Drosophila virilis FBgn0210194 I 0.804
GK11724 Drosophila willistoni FBgn0213735 I 0.804
GE10952 Drosophila yakuba FBgn0228782 I 0.804
ISCW018468 Ixodes scapularis ISCW018468 I 0.804
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.804
TC010848 Tribolium castaneum TC010848 I 0.804
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.804
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.804
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.804
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.804
LCUP007928 Lucilia cuprina LCUP007928 I 0.804
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.804
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.804
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.804
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.804
MDOA012885 Musca domestica MDOA012885 I 0.804
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.804
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.794
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.794
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.794
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.794
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.794
smad4a Danio rerio ENSDARG00000075226 I 0.794
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.794
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.794
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.794
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.794
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.794
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.794
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.794
smad4a Oryzias latipes ENSORLG00000005020 I 0.794
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.794
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.794
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.794
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.794
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.794
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.784
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.784
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.784
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.784
SMAD4 Bos taurus ENSBTAG00000006919 I 0.784
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.784
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.784
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.784
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.784
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.784
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.784
SMAD4 Equus caballus ENSECAG00000017857 I 0.784
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.784
SMAD4 Felis catus ENSFCAG00000005257 I 0.784
SMAD4 Homo sapiens ENSG00000141646 D 0.784
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.784
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.784
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.784
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.784
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.784
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.784
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.784
Smad4 Mus musculus ENSMUSG00000024515 D 0.784
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.784
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.784
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.784
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.784
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.784
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.784
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.784
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.784
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.784
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.784
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.784
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.784
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.784
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.784
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.784
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.784
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.784
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.784
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.784
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.784
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.784
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.784
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.784
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.784
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.784
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.784
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.784
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.784
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.784
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.784
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.784
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.784
AAH84196 Xenopus laevis AAH84196 I 0.784
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.784
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.784
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.784
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.782
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.775
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.775
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.775
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.775
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.775
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.775
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.775
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.775
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.775
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.775
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.775
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.775
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.775
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.775
EFV62078 Trichinella spiralis EFV62078 I 0.755
smad4 Ciona intestinalis ENSCING00000005559 I 0.755
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.755
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.755
ML02191a Mnemiopsis leidyi ML02191a I 0.755
D917_09719 Trichinella nativa D917_09719 I 0.755
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.745
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.745
Bm3575 Brugia malayi Bm3575 I 0.745
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.745
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.745
ASU_13433 Ascaris suum ASU_13433 I 0.745
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.745
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.745
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.745
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.745
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.735
LOAG_08923 Loa loa LOAG_08923 I 0.735
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.735
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.735
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.735
L596_g15 Steinernema carpocapsae L596_g15 I 0.735
L889_g28104 Steinernema feltiae L889_g28104 I 0.735
L893_g344 Steinernema glaseri L893_g344 I 0.735
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.735
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.735
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.735
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.727
D915_03789 Fasciola hepatica D915_03789 I 0.725
L898_g17086 Steinernema monticolum L898_g17086 I 0.725
CBN31444 Caenorhabditis brenneri CBN31444 I 0.716
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.716
L893_g15056 Steinernema glaseri L893_g15056 I 0.716
TCLT_0000412001 Thelazia callipaeda TCLT_0000412001 I 0.716
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.716
DICVIV_05422 Dictyocaulus viviparus DICVIV_05422 I 0.713
HPBE_0002536701 Heligmosomoides bakeri HPBE_0002536701 I 0.713
L889_g22387 Steinernema feltiae L889_g22387 I 0.713
NBR_0001377901 Nippostrongylus brasiliensis NBR_0001377901 I 0.713
WUBG_08631 Wuchereria bancrofti WUBG_08631 I 0.706
ACEP19585 Atta cephalotes ACEP19585 I 0.706
Bm5359 Brugia malayi Bm5359 I 0.706
CBG09090 Caenorhabditis briggsae CBG09090 I 0.706
CJA09693 Caenorhabditis japonica CJA09693 I 0.706
CRE04707 Caenorhabditis remanei CRE04707 I 0.706
sma-4 Caenorhabditis elegans WBGene00004858 D 0.706
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.706
SMU15001649 Schmidtea mediterranea SMU15001649 N 0.706
ALUE_0001111401 Ascaris lumbricoides ALUE_0001111401 I 0.706
ASU_10605 Ascaris suum ASU_10605 I 0.706
BTMF_0000952301 Brugia timori BTMF_0000952301 I 0.706
CGOC_0000897101 Cylicostephanus goldi CGOC_0000897101 I 0.706
HCOI00676200 Haemonchus contortus HCOI00676200 I 0.706
HCOI01928500 Haemonchus contortus HCOI01928500 I 0.706
HCOI02014300 Haemonchus contortus HCOI02014300 I 0.706
SSLN_0001332901 Schistocephalus solidus SSLN_0001332901 N 0.706
TELCIR_06960 Teladorsagia circumcincta TELCIR_06960 I 0.706
ASIM_0001219601 Anisakis simplex ASIM_0001219601 I 0.703