Bm3575 (Brugia malayi)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 Bm3575 T324392_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.784 0.784
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.784 0.784
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.784 0.784
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.784 0.784
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.784 0.784
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.784 0.784
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.784 0.784
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.784 0.784
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.784 0.784
sma-4
M02484_2.00 		Caenorhabditis elegans
NNCCAGACANN
NNTGTCTGGNN		 PBM
Weirauch et al.(2014)
pTH8996 		0.706 0.706
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
Bm3575y SMAD 110 211
Bm3575z SMAD 110 211

Links

Other SMAD family TFs
Other Brugia malayi TFs

232 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
BTMF_0000404601 Brugia timori BTMF_0000404601 I 1.000
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.990
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.971
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.971
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.971
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.971
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.971
LOAG_08923 Loa loa LOAG_08923 I 0.961
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.961
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.961
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.931
ASU_13433 Ascaris suum ASU_13433 I 0.922
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.882
EFV62078 Trichinella spiralis EFV62078 I 0.833
D917_09719 Trichinella nativa D917_09719 I 0.833
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.824
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.814
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.804
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.804
ACUA025512 Anopheles culicifacies ACUA025512 I 0.804
AATE010695 Anopheles atroparvus AATE010695 I 0.804
ACHR000067 Anopheles christyi ACHR000067 I 0.804
ACOM037505 Anopheles coluzzii ACOM037505 I 0.804
AARA004719 Anopheles arabiensis AARA004719 I 0.804
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.804
GB50071 Apis mellifera GB50071 I 0.804
AEPI002385 Anopheles epiroticus AEPI002385 I 0.804
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.804
HMEL002203 Heliconius melpomene HMEL002203 I 0.804
MCINX014520 Melitaea cinxia MCINX014520 I 0.804
NV12984 Nasonia vitripennis NV12984 I 0.804
KGM_12572 Danaus plexippus KGM_12572 I 0.804
SINV15516 Solenopsis invicta SINV15516 I 0.804
ADIR002761 Anopheles dirus ADIR002761 I 0.804
AGAP002902 Anopheles gambiae AGAP002902 I 0.804
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.804
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.804
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.804
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.804
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.804
AFUN009864 Anopheles funestus AFUN009864 I 0.804
AFAF011208 Anopheles farauti AFAF011208 I 0.804
AMAM019778 Anopheles maculatus AMAM019778 I 0.804
AMEM015931 Anopheles merus AMEM015931 I 0.804
AMIN000723 Anopheles minimus AMIN000723 I 0.804
OESDEN_03018 Oesophagostomum dentatum OESDEN_03018 I 0.794
L798_13939 Zootermopsis nevadensis L798_13939 I 0.794
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.794
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.794
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.794
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.794
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.794
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.794
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.794
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.794
SMAR013850 Strigamia maritima SMAR013850 I 0.794
CLEC002594 Cimex lectularius CLEC002594 I 0.794
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.794
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.794
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.794
AALB009485 Anopheles albimanus AALB009485 I 0.794
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.794
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.794
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.794
RPRC010188 Rhodnius prolixus RPRC010188 I 0.794
PHUM002670 Pediculus humanus PHUM002670 I 0.794
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.794
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.794
TC010848 Tribolium castaneum TC010848 I 0.794
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.794
ISCW018468 Ixodes scapularis ISCW018468 I 0.794
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.794
CapteG179368 Capitella teleta CapteG179368 I 0.794
ADAC007516 Anopheles darlingi ADAC007516 I 0.794
SMAD4 Danio rerio ENSDARG00000012649 I 0.794
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.794
AAEL013896 Aedes aegypti AAEL013896 I 0.794
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.794
SMAD4 Homo sapiens ENSG00000141646 D 0.784
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.784
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.784
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.784
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.784
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.784
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.784
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.784
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.784
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.784
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.784
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.784
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.784
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.784
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.784
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.784
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.784
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.784
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.784
AAH84196 Xenopus laevis AAH84196 I 0.784
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.784
LCUP007928 Lucilia cuprina LCUP007928 I 0.784
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.784
SMAD4 Bos taurus ENSBTAG00000006919 I 0.784
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.784
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.784
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.784
MDOA012885 Musca domestica MDOA012885 I 0.784
HCOI00676200 Haemonchus contortus HCOI00676200 I 0.784
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.784
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.784
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.784
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.784
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.784
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.784
SMAD4 Equus caballus ENSECAG00000017857 I 0.784
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.784
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.784
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.784
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.784
smad4a Danio rerio ENSDARG00000075226 I 0.784
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.784
SMAD4 Felis catus ENSFCAG00000005257 I 0.784
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.784
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.784
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.784
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.784
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.784
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.784
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.784
Med Drosophila melanogaster FBgn0011655 D 0.784
GH18642 Drosophila grimshawi FBgn0126109 I 0.784
GG11819 Drosophila erecta FBgn0104114 I 0.784
GF22974 Drosophila ananassae FBgn0099968 I 0.784
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.784
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.784
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.784
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.784
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.784
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.784
smad4a Oryzias latipes ENSORLG00000005020 I 0.784
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.784
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.784
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.784
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.784
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.784
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.784
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.784
GI23400 Drosophila mojavensis FBgn0146126 I 0.784
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.784
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.784
LotgiG131078 Lottia gigantea LotgiG131078 I 0.784
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.784
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.784
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.784
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.784
Smad4 Mus musculus ENSMUSG00000024515 D 0.784
GK11724 Drosophila willistoni FBgn0213735 I 0.784
GE10952 Drosophila yakuba FBgn0228782 I 0.784
GM16436 Drosophila sechellia FBgn0171351 I 0.784
GJ23092 Drosophila virilis FBgn0210194 I 0.784
GL23637 Drosophila persimilis FBgn0161227 I 0.784
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.782
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.775
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.775
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.775
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.775
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.775
EVEC_0000355201 Enterobius vermicularis EVEC_0000355201 I 0.775
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.775
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.775
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.775
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.775
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.775
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.775
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.765
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.765
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.765
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.765
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.765
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.765
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.765
HelroG88197 Helobdella robusta HelroG88197 I 0.765
ML02191a Mnemiopsis leidyi ML02191a I 0.765
maker-nMf.1.1.scaf02670-augustus-gene-0.3 Meloidogyne floridensis maker-nMf.1.1.scaf02670-augustus-gene-0.3 I 0.755
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.755
genemark-nMf.1.1.scaf08549-processed-gene-0.3 Meloidogyne floridensis genemark-nMf.1.1.scaf08549-processed-gene-0.3 N 0.755
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.755
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.755
Minc15475 Meloidogyne incognita Minc15475 N 0.755
Minc06628 Meloidogyne incognita Minc06628 I 0.755
smad4 Ciona intestinalis ENSCING00000005559 I 0.755
Minc05381 Meloidogyne incognita Minc05381 I 0.755
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.745
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.745
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.745
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.745
HelroG76435 Helobdella robusta HelroG76435 I 0.745
MhA1_Contig1148.frz3.fgene1 Meloidogyne hapla MhA1_Contig1148.frz3.fgene1 N 0.745
L898_g17086 Steinernema monticolum L898_g17086 I 0.735
L893_g344 Steinernema glaseri L893_g344 I 0.735
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.735
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.735
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.735
ANCDUO_23180 Ancylostoma duodenale ANCDUO_23180 N 0.730
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.725
L898_g26477 Steinernema monticolum L898_g26477 I 0.725
TCLT_0000412001 Thelazia callipaeda TCLT_0000412001 I 0.716
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.716
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.716
L893_g15056 Steinernema glaseri L893_g15056 I 0.716
L889_g28104 Steinernema feltiae L889_g28104 I 0.716
L596_g15 Steinernema carpocapsae L596_g15 I 0.716
BXY_0211100 Bursaphelenchus xylophilus BXY_0211100 N 0.716
L889_g6780 Steinernema feltiae L889_g6780 I 0.716
CRE04707 Caenorhabditis remanei CRE04707 I 0.713
L889_g22387 Steinernema feltiae L889_g22387 I 0.713
CBN31444 Caenorhabditis brenneri CBN31444 I 0.713
L892_g19326 Steinernema scapterisci L892_g19326 N 0.707
ANCCEY_04158 Ancylostoma ceylanicum ANCCEY_04158 N 0.706
ASU_10605 Ascaris suum ASU_10605 I 0.706
ACEP19585 Atta cephalotes ACEP19585 I 0.706
WUBG_08631 Wuchereria bancrofti WUBG_08631 I 0.706
ALUE_0001111401 Ascaris lumbricoides ALUE_0001111401 I 0.706
CJA09693 Caenorhabditis japonica CJA09693 I 0.706
BTMF_0000952301 Brugia timori BTMF_0000952301 I 0.706
Bm5359 Brugia malayi Bm5359 I 0.706
nLs.2.1.2.g01829 Litomosoides sigmodontis nLs.2.1.2.g01829 I 0.706
L893_g8358 Steinernema glaseri L893_g8358 N 0.706
sma-4 Caenorhabditis elegans WBGene00004858 D 0.706
LOAG_05337 Loa loa LOAG_05337 I 0.703
L892_g4495 Steinernema scapterisci L892_g4495 I 0.703
L596_g26024 Steinernema carpocapsae L596_g26024 I 0.703