LOAG_08923 (Loa loa)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 LOAG_08923 T325141_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.765 0.765
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.765 0.765
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.765 0.765
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.765 0.765
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.765 0.765
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.765 0.765
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.765 0.765
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.765 0.765
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.765 0.765
sma-4
M02484_2.00 		Caenorhabditis elegans
NNCCAGACANN
NNTGTCTGGNN		 PBM
Weirauch et al.(2014)
pTH8996 		0.706 0.706
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
EFO19570.2 SMAD 99 200

Links

Other SMAD family TFs
Other Loa loa TFs

216 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Bm3575 Brugia malayi Bm3575 I 0.961
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.961
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.951
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.951
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.951
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.951
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.951
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.951
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.941
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.931
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.922
ASU_13433 Ascaris suum ASU_13433 I 0.922
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.892
EFV62078 Trichinella spiralis EFV62078 I 0.833
D917_09719 Trichinella nativa D917_09719 I 0.833
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.814
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.804
OESDEN_03018 Oesophagostomum dentatum OESDEN_03018 I 0.804
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.804
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.804
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.804
ML02191a Mnemiopsis leidyi ML02191a I 0.794
HCOI00676200 Haemonchus contortus HCOI00676200 I 0.794
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.784
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.784
AGAP002902 Anopheles gambiae AGAP002902 I 0.784
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.784
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.784
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.784
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.784
GB50071 Apis mellifera GB50071 I 0.784
HMEL002203 Heliconius melpomene HMEL002203 I 0.784
KGM_12572 Danaus plexippus KGM_12572 I 0.784
MCINX014520 Melitaea cinxia MCINX014520 I 0.784
NV12984 Nasonia vitripennis NV12984 I 0.784
SINV15516 Solenopsis invicta SINV15516 I 0.784
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.784
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.784
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.784
AARA004719 Anopheles arabiensis AARA004719 I 0.784
AATE010695 Anopheles atroparvus AATE010695 I 0.784
ACHR000067 Anopheles christyi ACHR000067 I 0.784
ACOM037505 Anopheles coluzzii ACOM037505 I 0.784
ACUA025512 Anopheles culicifacies ACUA025512 I 0.784
ADIR002761 Anopheles dirus ADIR002761 I 0.784
AEPI002385 Anopheles epiroticus AEPI002385 I 0.784
AFAF011208 Anopheles farauti AFAF011208 I 0.784
AFUN009864 Anopheles funestus AFUN009864 I 0.784
AMAM019778 Anopheles maculatus AMAM019778 I 0.784
AMEM015931 Anopheles merus AMEM015931 I 0.784
AMIN000723 Anopheles minimus AMIN000723 I 0.784
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.784
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.784
AAEL013896 Aedes aegypti AAEL013896 I 0.775
ADAC007516 Anopheles darlingi ADAC007516 I 0.775
CapteG179368 Capitella teleta CapteG179368 I 0.775
SMAD4 Danio rerio ENSDARG00000012649 I 0.775
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.775
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.775
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.775
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.775
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.775
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.775
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.775
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.775
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.775
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.775
ISCW018468 Ixodes scapularis ISCW018468 I 0.775
L798_13939 Zootermopsis nevadensis L798_13939 I 0.775
PHUM002670 Pediculus humanus PHUM002670 I 0.775
RPRC010188 Rhodnius prolixus RPRC010188 I 0.775
SMAR013850 Strigamia maritima SMAR013850 I 0.775
TC010848 Tribolium castaneum TC010848 I 0.775
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.775
CLEC002594 Cimex lectularius CLEC002594 I 0.775
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.775
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.775
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.775
Minc05381 Meloidogyne incognita Minc05381 I 0.775
Minc06628 Meloidogyne incognita Minc06628 I 0.775
Minc15475 Meloidogyne incognita Minc15475 N 0.775
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.775
AALB009485 Anopheles albimanus AALB009485 I 0.775
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.775
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.775
genemark-nMf.1.1.scaf08549-processed-gene-0.3 Meloidogyne floridensis genemark-nMf.1.1.scaf08549-processed-gene-0.3 N 0.775
maker-nMf.1.1.scaf02670-augustus-gene-0.3 Meloidogyne floridensis maker-nMf.1.1.scaf02670-augustus-gene-0.3 I 0.775
MhA1_Contig1148.frz3.fgene1 Meloidogyne hapla MhA1_Contig1148.frz3.fgene1 N 0.775
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.765
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.765
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.765
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.765
SMAD4 Bos taurus ENSBTAG00000006919 I 0.765
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.765
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.765
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.765
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.765
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.765
smad4a Danio rerio ENSDARG00000075226 I 0.765
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.765
SMAD4 Equus caballus ENSECAG00000017857 I 0.765
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.765
SMAD4 Felis catus ENSFCAG00000005257 I 0.765
SMAD4 Homo sapiens ENSG00000141646 D 0.765
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.765
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.765
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.765
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.765
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.765
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.765
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.765
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.765
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.765
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.765
Smad4 Mus musculus ENSMUSG00000024515 D 0.765
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.765
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.765
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.765
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.765
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.765
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.765
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.765
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.765
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.765
smad4a Oryzias latipes ENSORLG00000005020 I 0.765
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.765
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.765
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.765
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.765
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.765
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.765
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.765
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.765
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.765
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.765
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.765
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.765
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.765
Med Drosophila melanogaster FBgn0011655 D 0.765
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.765
GF22974 Drosophila ananassae FBgn0099968 I 0.765
GG11819 Drosophila erecta FBgn0104114 I 0.765
GH18642 Drosophila grimshawi FBgn0126109 I 0.765
GI23400 Drosophila mojavensis FBgn0146126 I 0.765
GL23637 Drosophila persimilis FBgn0161227 I 0.765
GM16436 Drosophila sechellia FBgn0171351 I 0.765
GJ23092 Drosophila virilis FBgn0210194 I 0.765
GK11724 Drosophila willistoni FBgn0213735 I 0.765
GE10952 Drosophila yakuba FBgn0228782 I 0.765
HelroG88197 Helobdella robusta HelroG88197 I 0.765
LotgiG131078 Lottia gigantea LotgiG131078 I 0.765
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.765
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.765
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.765
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.765
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.765
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.765
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.765
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.765
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.765
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.765
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.765
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.765
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.765
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.765
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.765
AAH84196 Xenopus laevis AAH84196 I 0.765
LCUP007928 Lucilia cuprina LCUP007928 I 0.765
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.765
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.765
MDOA012885 Musca domestica MDOA012885 I 0.765
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.755
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.755
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.755
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.755
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.755
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.755
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.755
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.755
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.755
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.755
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.755
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.755
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.755
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.755
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.755
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.745
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.745
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.745
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.745
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.745
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.745
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.745
EVEC_0000355201 Enterobius vermicularis EVEC_0000355201 I 0.745
L898_g17086 Steinernema monticolum L898_g17086 I 0.745
smad4 Ciona intestinalis ENSCING00000005559 I 0.735
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.735
HelroG76435 Helobdella robusta HelroG76435 I 0.735
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.735
L893_g344 Steinernema glaseri L893_g344 I 0.735
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.725
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.725
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.716
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.716
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.716
ANCCEY_04158 Ancylostoma ceylanicum ANCCEY_04158 N 0.716
L596_g15 Steinernema carpocapsae L596_g15 I 0.716
L889_g28104 Steinernema feltiae L889_g28104 I 0.716
CJA09693 Caenorhabditis japonica CJA09693 I 0.706
CRE04707 Caenorhabditis remanei CRE04707 I 0.706
sma-4 Caenorhabditis elegans WBGene00004858 D 0.706
BXY_0211100 Bursaphelenchus xylophilus BXY_0211100 N 0.706
L893_g15056 Steinernema glaseri L893_g15056 I 0.706
L893_g8358 Steinernema glaseri L893_g8358 N 0.706
L898_g26477 Steinernema monticolum L898_g26477 I 0.706
L889_g22387 Steinernema feltiae L889_g22387 I 0.703