SMAD4 (Takifugu rubripes)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSTRUG00000014045 T325008_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.990 0.990
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.990 0.990
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.990 0.990
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.990 0.990
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.990 0.990
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.990 0.990
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.990 0.990
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.951 0.951
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.951 0.951
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSTRUP00000035926 SMAD 36 137
ENSTRUP00000035927 SMAD 9 110
ENSTRUP00000035928 SMAD 9 110

Links

Other SMAD family TFs
Other Takifugu rubripes TFs

229 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SMAD4 Homo sapiens ENSG00000141646 D 1.000
SMAD4 Microcebus murinus ENSMICG00000017525 I 1.000
SMAD4 Oryzias latipes ENSORLG00000007703 I 1.000
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 1.000
SMAD4 Pteropus vampyrus ENSPVAG00000004261 I 1.000
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 1.000
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 1.000
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.990
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.990
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.990
SMAD4 Bos taurus ENSBTAG00000006919 I 0.990
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.990
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.990
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.990
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.990
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.990
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.990
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.990
SMAD4 Equus caballus ENSECAG00000017857 I 0.990
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.990
SMAD4 Felis catus ENSFCAG00000005257 I 0.990
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.990
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.990
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.990
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.990
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.990
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.990
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.990
Smad4 Mus musculus ENSMUSG00000024515 D 0.990
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.990
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.990
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.990
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.990
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.990
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.990
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.990
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.990
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.990
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.990
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.990
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.990
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.990
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.990
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.990
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.990
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.990
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.990
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.990
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.990
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.990
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.990
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.990
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.990
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.990
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.990
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.990
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.990
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.990
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.990
AAH84196 Xenopus laevis AAH84196 I 0.990
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.990
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.990
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.980
smad4a Danio rerio ENSDARG00000075226 I 0.980
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.980
smad4a Oryzias latipes ENSORLG00000005020 I 0.980
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.980
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.980
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.971
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.971
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.971
ISCW018468 Ixodes scapularis ISCW018468 I 0.971
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.971
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.971
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.971
AAEL013896 Aedes aegypti AAEL013896 I 0.961
SMAD4 Danio rerio ENSDARG00000012649 I 0.961
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.961
L798_13939 Zootermopsis nevadensis L798_13939 I 0.961
PHUM002670 Pediculus humanus PHUM002670 I 0.961
SMAR013850 Strigamia maritima SMAR013850 I 0.961
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.961
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.951
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.951
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.951
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.951
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.951
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.951
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.951
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.951
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.951
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.951
Med Drosophila melanogaster FBgn0011655 D 0.951
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.951
GF22974 Drosophila ananassae FBgn0099968 I 0.951
GG11819 Drosophila erecta FBgn0104114 I 0.951
GH18642 Drosophila grimshawi FBgn0126109 I 0.951
GI23400 Drosophila mojavensis FBgn0146126 I 0.951
GL23637 Drosophila persimilis FBgn0161227 I 0.951
GM16436 Drosophila sechellia FBgn0171351 I 0.951
GJ23092 Drosophila virilis FBgn0210194 I 0.951
GK11724 Drosophila willistoni FBgn0213735 I 0.951
GE10952 Drosophila yakuba FBgn0228782 I 0.951
GB50071 Apis mellifera GB50071 I 0.951
NV12984 Nasonia vitripennis NV12984 I 0.951
SINV15516 Solenopsis invicta SINV15516 I 0.951
TC010848 Tribolium castaneum TC010848 I 0.951
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.951
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.951
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.951
LCUP007928 Lucilia cuprina LCUP007928 I 0.951
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.951
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.951
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.951
MDOA012885 Musca domestica MDOA012885 I 0.951
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.941
AGAP002902 Anopheles gambiae AGAP002902 I 0.941
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.941
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.941
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.941
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.941
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.941
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.941
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.941
HMEL002203 Heliconius melpomene HMEL002203 I 0.941
KGM_12572 Danaus plexippus KGM_12572 I 0.941
MCINX014520 Melitaea cinxia MCINX014520 I 0.941
RPRC010188 Rhodnius prolixus RPRC010188 I 0.941
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.941
CLEC002594 Cimex lectularius CLEC002594 I 0.941
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.941
AARA004719 Anopheles arabiensis AARA004719 I 0.941
AATE010695 Anopheles atroparvus AATE010695 I 0.941
ACHR000067 Anopheles christyi ACHR000067 I 0.941
ACOM037505 Anopheles coluzzii ACOM037505 I 0.941
ACUA025512 Anopheles culicifacies ACUA025512 I 0.941
ADIR002761 Anopheles dirus ADIR002761 I 0.941
AEPI002385 Anopheles epiroticus AEPI002385 I 0.941
AFAF011208 Anopheles farauti AFAF011208 I 0.941
AFUN009864 Anopheles funestus AFUN009864 I 0.941
AMAM019778 Anopheles maculatus AMAM019778 I 0.941
AMEM015931 Anopheles merus AMEM015931 I 0.941
AMIN000723 Anopheles minimus AMIN000723 I 0.941
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.941
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.941
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.941
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.931
LotgiG131078 Lottia gigantea LotgiG131078 I 0.931
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.931
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.931
ADAC007516 Anopheles darlingi ADAC007516 I 0.922
CapteG179368 Capitella teleta CapteG179368 I 0.922
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.922
AALB009485 Anopheles albimanus AALB009485 I 0.922
smad4 Ciona intestinalis ENSCING00000005559 I 0.912
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.912
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.912
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.902
CGI_10018464 Crassostrea gigas CGI_10018464 I 0.893
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.892
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.892
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.892
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.892
HelroG88197 Helobdella robusta HelroG88197 I 0.892
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.882
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.882
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.873
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.873
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.873
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.863
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.853
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.853
ML02191a Mnemiopsis leidyi ML02191a I 0.853
Aan_R014474 Calypte anna Aan_R014474 I 0.845
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.843
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.843
ACEP19585 Atta cephalotes ACEP19585 I 0.833
EFV62078 Trichinella spiralis EFV62078 I 0.833
D917_09719 Trichinella nativa D917_09719 I 0.833
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.821
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.814
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.804
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.804
Bm3575 Brugia malayi Bm3575 I 0.794
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.794
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.794
D915_03789 Fasciola hepatica D915_03789 I 0.794
T265_11013 Opisthorchis viverrini T265_11013 I 0.794
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.784
ASU_13433 Ascaris suum ASU_13433 I 0.784
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.784
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.784
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.784
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.784
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.784
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.775
HelroG76435 Helobdella robusta HelroG76435 I 0.775
LOAG_08923 Loa loa LOAG_08923 I 0.775
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.775
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.775
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.775
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.767
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.765
D918_00298 Trichuris suis D918_00298 I 0.760
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.755
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.745
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.745
Sakowv30001112m.g Saccoglossus kowalevskii Sakowv30001112m.g I 0.731
Smp_033950 Schistosoma mansoni Smp_033950 I 0.716
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.716
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.716
OESDEN_03018 Oesophagostomum dentatum OESDEN_03018 I 0.716
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.716
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.716
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.716
HPBE_0001599301 Heligmosomoides bakeri HPBE_0001599301 I 0.714
EVEC_0000355201 Enterobius vermicularis EVEC_0000355201 I 0.707
Minc05381 Meloidogyne incognita Minc05381 I 0.706
Minc06628 Meloidogyne incognita Minc06628 I 0.706
HCOI00676200 Haemonchus contortus HCOI00676200 I 0.706
L889_g28104 Steinernema feltiae L889_g28104 I 0.706
L893_g15056 Steinernema glaseri L893_g15056 I 0.706
L893_g344 Steinernema glaseri L893_g344 I 0.706
L898_g17086 Steinernema monticolum L898_g17086 I 0.706
maker-nMf.1.1.scaf02670-augustus-gene-0.3 Meloidogyne floridensis maker-nMf.1.1.scaf02670-augustus-gene-0.3 I 0.706
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.706
CBN31444 Caenorhabditis brenneri CBN31444 I 0.703
L889_g22387 Steinernema feltiae L889_g22387 I 0.703