HelroG88197 (Helobdella robusta)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 HelroG88197 T325117_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.882 0.882
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.882 0.882
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.882 0.882
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.882 0.882
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.882 0.882
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.882 0.882
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.882 0.882
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.882 0.882
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.882 0.882
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HelroP88197 SMAD 71 172

Links

Other SMAD family TFs
Other Helobdella robusta TFs

227 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.912
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.912
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.902
ADAC007516 Anopheles darlingi ADAC007516 I 0.902
CapteG179368 Capitella teleta CapteG179368 I 0.902
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.902
GB50071 Apis mellifera GB50071 I 0.902
ISCW018468 Ixodes scapularis ISCW018468 I 0.902
NV12984 Nasonia vitripennis NV12984 I 0.902
SINV15516 Solenopsis invicta SINV15516 I 0.902
TC010848 Tribolium castaneum TC010848 I 0.902
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.902
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.902
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.902
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.902
AALB009485 Anopheles albimanus AALB009485 I 0.902
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.902
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.902
AAEL013896 Aedes aegypti AAEL013896 I 0.892
AGAP002902 Anopheles gambiae AGAP002902 I 0.892
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.892
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.892
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.892
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.892
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.892
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.892
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.892
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.892
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.892
HMEL002203 Heliconius melpomene HMEL002203 I 0.892
KGM_12572 Danaus plexippus KGM_12572 I 0.892
L798_13939 Zootermopsis nevadensis L798_13939 I 0.892
LotgiG131078 Lottia gigantea LotgiG131078 I 0.892
MCINX014520 Melitaea cinxia MCINX014520 I 0.892
PHUM002670 Pediculus humanus PHUM002670 I 0.892
SMAR013850 Strigamia maritima SMAR013850 I 0.892
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.892
AARA004719 Anopheles arabiensis AARA004719 I 0.892
AATE010695 Anopheles atroparvus AATE010695 I 0.892
ACHR000067 Anopheles christyi ACHR000067 I 0.892
ACOM037505 Anopheles coluzzii ACOM037505 I 0.892
ACUA025512 Anopheles culicifacies ACUA025512 I 0.892
ADIR002761 Anopheles dirus ADIR002761 I 0.892
AEPI002385 Anopheles epiroticus AEPI002385 I 0.892
AFAF011208 Anopheles farauti AFAF011208 I 0.892
AFUN009864 Anopheles funestus AFUN009864 I 0.892
AMAM019778 Anopheles maculatus AMAM019778 I 0.892
AMEM015931 Anopheles merus AMEM015931 I 0.892
AMIN000723 Anopheles minimus AMIN000723 I 0.892
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.892
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.892
SMAD4 Homo sapiens ENSG00000141646 D 0.891
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.882
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.882
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.882
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.882
SMAD4 Bos taurus ENSBTAG00000006919 I 0.882
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.882
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.882
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.882
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.882
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.882
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.882
SMAD4 Equus caballus ENSECAG00000017857 I 0.882
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.882
SMAD4 Felis catus ENSFCAG00000005257 I 0.882
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.882
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.882
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.882
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.882
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.882
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.882
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.882
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.882
Smad4 Mus musculus ENSMUSG00000024515 D 0.882
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.882
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.882
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.882
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.882
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.882
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.882
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.882
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.882
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.882
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.882
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.882
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.882
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.882
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.882
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.882
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.882
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.882
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.882
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.882
Med Drosophila melanogaster FBgn0011655 D 0.882
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.882
GF22974 Drosophila ananassae FBgn0099968 I 0.882
GG11819 Drosophila erecta FBgn0104114 I 0.882
GH18642 Drosophila grimshawi FBgn0126109 I 0.882
GI23400 Drosophila mojavensis FBgn0146126 I 0.882
GL23637 Drosophila persimilis FBgn0161227 I 0.882
GM16436 Drosophila sechellia FBgn0171351 I 0.882
GJ23092 Drosophila virilis FBgn0210194 I 0.882
GK11724 Drosophila willistoni FBgn0213735 I 0.882
GE10952 Drosophila yakuba FBgn0228782 I 0.882
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.882
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.882
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.882
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.882
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.882
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.882
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.882
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.882
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.882
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.882
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.882
AAH84196 Xenopus laevis AAH84196 I 0.882
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.882
LCUP007928 Lucilia cuprina LCUP007928 I 0.882
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.882
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.882
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.882
MDOA012885 Musca domestica MDOA012885 I 0.882
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.881
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.873
SMAD4 Danio rerio ENSDARG00000012649 I 0.873
smad4a Danio rerio ENSDARG00000075226 I 0.873
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.873
smad4a Oryzias latipes ENSORLG00000005020 I 0.873
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.873
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.873
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.873
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.873
RPRC010188 Rhodnius prolixus RPRC010188 I 0.873
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.873
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.873
CLEC002594 Cimex lectularius CLEC002594 I 0.873
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.873
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.863
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.863
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.863
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.863
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.863
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.863
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.853
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.853
smad4 Ciona intestinalis ENSCING00000005559 I 0.853
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.853
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.853
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.853
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.853
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.853
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.853
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.853
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.853
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.853
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.853
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.843
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.843
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.833
EFV62078 Trichinella spiralis EFV62078 I 0.833
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.833
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.833
D917_09719 Trichinella nativa D917_09719 I 0.833
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.824
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.824
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.824
ML02191a Mnemiopsis leidyi ML02191a I 0.824
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.824
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.814
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.814
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.814
HelroG76435 Helobdella robusta HelroG76435 I 0.814
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.814
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.814
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.804
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.804
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.800
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.786
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.784
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.784
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.784
Aan_R014474 Calypte anna Aan_R014474 I 0.776
ACEP19585 Atta cephalotes ACEP19585 I 0.775
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.775
ASU_13433 Ascaris suum ASU_13433 I 0.775
D915_03789 Fasciola hepatica D915_03789 I 0.775
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.775
L596_g15 Steinernema carpocapsae L596_g15 I 0.775
L889_g28104 Steinernema feltiae L889_g28104 I 0.775
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.775
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.775
Bm3575 Brugia malayi Bm3575 I 0.765
LOAG_08923 Loa loa LOAG_08923 I 0.765
SMU15001649 Schmidtea mediterranea SMU15001649 N 0.765
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.765
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.765
T265_11013 Opisthorchis viverrini T265_11013 I 0.765
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.755
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.755
L893_g344 Steinernema glaseri L893_g344 I 0.755
L898_g17086 Steinernema monticolum L898_g17086 I 0.755
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.755
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.755
L893_g15056 Steinernema glaseri L893_g15056 I 0.745
L889_g22387 Steinernema feltiae L889_g22387 I 0.743
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.735
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.725
Smp_033950 Schistosoma mansoni Smp_033950 I 0.725
MhA1_Contig1148.frz3.fgene1 Meloidogyne hapla MhA1_Contig1148.frz3.fgene1 N 0.725
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.725
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.721
Minc05381 Meloidogyne incognita Minc05381 I 0.716
Minc06628 Meloidogyne incognita Minc06628 I 0.716
maker-nMf.1.1.scaf02670-augustus-gene-0.3 Meloidogyne floridensis maker-nMf.1.1.scaf02670-augustus-gene-0.3 I 0.716
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.716
CBG09090 Caenorhabditis briggsae CBG09090 I 0.706
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.706
Minc15475 Meloidogyne incognita Minc15475 N 0.706
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.706
genemark-nMf.1.1.scaf08549-processed-gene-0.3 Meloidogyne floridensis genemark-nMf.1.1.scaf08549-processed-gene-0.3 N 0.706
L893_g8358 Steinernema glaseri L893_g8358 N 0.706
nLs.2.1.2.g01829 Litomosoides sigmodontis nLs.2.1.2.g01829 I 0.706
OESDEN_03018 Oesophagostomum dentatum OESDEN_03018 I 0.706
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.706
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.706
CRE04707 Caenorhabditis remanei CRE04707 I 0.703