ZNF449 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000173275 T095127_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF449
M04560_2.00
Homo sapiens
NTGYTKGCWCGCGAB

VTCGCGWGCMARCAN
SELEX
Yin et al.(2017)
ZNF449_eDBD_HT-SELEX_1
(Direct) (Direct)
ZNF449
M04561_2.00
Homo sapiens
RCGCCCAACC

GGTTGGGCGY
SELEX
Yin et al.(2017)
ZNF449_eDBD_HT-SELEX_2
(Direct) (Direct)
ZNF449
M04562_2.00
Homo sapiens
MMGCCCMACC

GGTKGGGCKK
SELEX
Yin et al.(2017)
ZNF449_eDBD_Methyl-HT-SELEX_1
(Direct) (Direct)
ZNF449
M04563_2.00
Homo sapiens
NTGYTKGCDCGCGWB

VWCGCGHGCMARCAN
SELEX
Yin et al.(2017)
ZNF449_eDBD_Methyl-HT-SELEX_2
(Direct) (Direct)
ZNF449
M08344_2.00
Homo sapiens
NNVAGCCCARCCHNNNNNNNN

NNNNNNNNDGGYTGGGCTBNN
ChIP-seq
Schmitges et al.(2016)
Q6P9G9_1-7.RCADE
(Direct) (Direct)
ZNF449
M08922_2.00
Homo sapiens
VAGCCCARCCN

NGGYTGGGCTB
Misc
Kulakovskiy et al.(2013)
ZN449_HUMAN.H11MO.0.C
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000339585 C2H2 ZF 323 345
ENSP00000339585 C2H2 ZF 351 373
ENSP00000339585 C2H2 ZF 379 401
ENSP00000339585 C2H2 ZF 407 429
ENSP00000339585 C2H2 ZF 435 457
ENSP00000339585 C2H2 ZF 463 485
ENSP00000339585 C2H2 ZF 491 513

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

33 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSP00000339585 Macaca fascicularis ENSP00000339585 I 0.827
ENSPANG00000012789 Papio anubis ENSPANG00000012789 I 0.827
ENSPPYG00000020749 Pongo abelii ENSPPYG00000020749 I 0.827
ZNF449 Pan troglodytes ENSPTRG00000022299 I 0.827
ZNF449 Gorilla gorilla ENSGGOG00000000032 I 0.827
ZNF449 Macaca mulatta ENSMMUG00000008108 I 0.827
ZNF449 Callithrix jacchus ENSCJAG00000014517 I 0.827
ENSCSAG00000007689 Chlorocebus sabaeus ENSCSAG00000007689 I 0.827
ENSNLEG00000002174 Nomascus leucogenys ENSNLEG00000002174 I 0.826
ENSEEUG00000003860 Erinaceus europaeus ENSEEUG00000003860 I 0.826
ZNF449 Bos taurus ENSBTAG00000018090 I 0.824
ZNF449 Canis familiaris ENSCAFG00000018905 I 0.824
ZNF449 Pteropus vampyrus ENSPVAG00000006757 I 0.824
ZNF449 Equus caballus ENSECAG00000003581 I 0.824
ZNF449 Sus scrofa ENSSSCG00000012691 I 0.824
ZNF449 Tursiops truncatus ENSTTRG00000010555 I 0.824
ENSSTOG00000024213 Ictidomys tridecemlineatus ENSSTOG00000024213 I 0.824
ZNF449 Oryctolagus cuniculus ENSOCUG00000014649 I 0.824
ENSOARG00000011892 Ovis aries ENSOARG00000011892 I 0.824
ENSBTAP00000024080-D1 Bos grunniens ENSBTAP00000024080-D1 I 0.824
ENSFCAG00000024967 Felis catus ENSFCAG00000024967 I 0.824
ENSAMEG00000011267 Ailuropoda melanoleuca ENSAMEG00000011267 I 0.824
ENSMPUG00000012654 Mustela putorius furo ENSMPUG00000012654 I 0.824
Myotis_brandtii_ZNF449_10001399 Myotis brandtii Myotis_brandtii_ZNF449_10001399 I 0.824
ENSCPOG00000004042 Cavia porcellus ENSCPOG00000004042 I 0.823
ENSETEG00000009064 Echinops telfairi ENSETEG00000009064 I 0.823
ZNF449 Vicugna pacos ENSVPAG00000002342 I 0.823
ZNF449 Otolemur garnettii ENSOGAG00000003684 I 0.822
Zfp449 Rattus norvegicus ENSRNOG00000050562 I 0.820
Zfp449 Mus musculus ENSMUSG00000073176 I 0.819
Zfp449 Dipodomys ordii ENSDORG00000003522 I 0.819
ZNF449 Microcebus murinus ENSMICG00000003164 I 0.817
ENSLAFG00000017131 Loxodonta africana ENSLAFG00000017131 I 0.812