ENSP00000020945-D1 (Bos grunniens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000020945-D1 T134880_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
SNAI2
M00221_2.00
Homo sapiens
HACYTGH

DCARGTD
PBM
Barrera et al.(2016)
SNAI2_REF
0.815 0.965
SNAI2
M02873_2.00
Homo sapiens
VCACCTGYN

NRCAGGTGB
SELEX
Jolma et al.(2013)
SNAI2_1
0.815 0.965
SNAI2
M04392_2.00
Homo sapiens
YGCACCTGYY

RRCAGGTGCR
SELEX
Yin et al.(2017)
SNAI2_eDBD_HT-SELEX
0.815 0.965
SNAI2
M04394_2.00
Homo sapiens
YRCACCTGYY

RRCAGGTGYR
SELEX
Yin et al.(2017)
SNAI2_FL_HT-SELEX
0.815 0.965
SNAI2
M08853_2.00
Homo sapiens
NVCACCTGYY

RRCAGGTGBN
Misc
Kulakovskiy et al.(2013)
SNAI2_HUMAN.H11MO.0.A
0.815 0.965
Snai2
M08973_2.00
Mus musculus
VNRCACCTGYY

RRCAGGTGYNB
Misc
Kulakovskiy et al.(2013)
SNAI2_MOUSE.H11MO.0.A
0.815 0.965
SNAI2
M10102_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SLUG_Q6_01
0.815 0.965
SNAI2
M10103_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SLUG_Q6_02
0.815 0.965
SNAI2
M10104_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SLUG_Q6
0.815 0.965
SNAI2
M00220_2.00
Homo sapiens
NHACCTGY

RCAGGTDN
PBM
Barrera et al.(2016)
SNAI2_D119E
0.815 0.965
SNAI2
M04393_2.00
Homo sapiens
YRCACCTGYN

NRCAGGTGYR
SELEX
Yin et al.(2017)
SNAI2_eDBD_Methyl-HT-SELEX
0.815 0.965
SNAI2
M04395_2.00
Homo sapiens
YRCACCTGYN

NRCAGGTGYR
SELEX
Yin et al.(2017)
SNAI2_FL_Methyl-HT-SELEX
0.815 0.965
SNAI2
M00222_2.00
Homo sapiens
HACYTGHNNN

NNNDCARGTD
PBM
Barrera et al.(2016)
SNAI2_T234I
0.811 0.956
esg
M06050_2.00
Drosophila melanogaster
CACCTGH

DCAGGTG
B1H
Zhu et al.(2011)
esg_SANGER_2.5_FBgn0001981
0.769 0.825
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000020945-D1 C2H2 ZF 128 150
ENSP00000020945-D1 C2H2 ZF 159 181
ENSP00000020945-D1 C2H2 ZF 185 207
ENSP00000020945-D1 C2H2 ZF 213 235
ENSP00000020945-D1 C2H2 ZF 241 262

Links

Other C2H2 ZF family TFs
Other Bos grunniens TFs

100 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSOARG00000013030 Ovis aries ENSOARG00000013030 I 0.827
SNAI2 Bos taurus ENSBTAG00000013227 I 0.827
ENSSSCG00000024404 Sus scrofa ENSSSCG00000024404 I 0.823
ENSSSCG00000026570 Sus scrofa ENSSSCG00000026570 I 0.823
ENSMPUG00000010793 Mustela putorius furo ENSMPUG00000010793 I 0.815
Snai2 Rattus norvegicus ENSRNOG00000047699 I 0.815
Snai2 Mus musculus ENSMUSG00000022676 D 0.815
SNAI2 Macaca mulatta ENSMMUG00000016195 I 0.815
SNAI2 Microcebus murinus ENSMICG00000000335 I 0.815
ENSP00000380034 Macaca fascicularis ENSP00000380034 I 0.815
ENSNLEG00000013421 Nomascus leucogenys ENSNLEG00000013421 I 0.815
SNAI2 Myotis lucifugus ENSMLUG00000001086 I 0.815
SNAI2 Otolemur garnettii ENSOGAG00000010500 I 0.815
ENSPPYG00000018578 Pongo abelii ENSPPYG00000018578 I 0.815
SNAI2 Pan troglodytes ENSPTRG00000020235 I 0.815
SNAI2 Procavia capensis ENSPCAG00000001788 I 0.815
ENSPANG00000017540 Papio anubis ENSPANG00000017540 I 0.815
Myotis_brandtii_Snai2_10018131 Myotis brandtii Myotis_brandtii_Snai2_10018131 I 0.815
ENSSTOG00000028743 Ictidomys tridecemlineatus ENSSTOG00000028743 I 0.815
SNAI2 Oryctolagus cuniculus ENSOCUG00000012254 I 0.815
SNAI2 Loxodonta africana ENSLAFG00000009299 I 0.815
ENSCSAG00000014787 Chlorocebus sabaeus ENSCSAG00000014787 I 0.815
SNAI2 Dasypus novemcinctus ENSDNOG00000035997 I 0.815
SNAI2 Felis catus ENSFCAG00000015779 I 0.815
ENSCPOG00000014827 Cavia porcellus ENSCPOG00000014827 I 0.815
SNAI2 Callithrix jacchus ENSCJAG00000013499 I 0.815
ENSAMEG00000009606 Ailuropoda melanoleuca ENSAMEG00000009606 I 0.815
SNAI2 Canis familiaris ENSCAFG00000006638 I 0.815
SNAI2 Choloepus hoffmanni ENSCHOG00000007046 I 0.815
SNAI2 Homo sapiens ENSG00000019549 D 0.815
SNAI2 Equus caballus ENSECAG00000010120 I 0.815
SNAI2 Gorilla gorilla ENSGGOG00000000959 I 0.815
Tal_R003673 Tyto alba Tal_R003673 I 0.813
Gfo_R012649 Geospiza fortis Gfo_R012649 I 0.813
snai2 Xenopus tropicalis XB-GENE-487371 I 0.813
snai2.L Xenopus laevis XB-GENE-6255814 I 0.813
snai2.S Xenopus laevis XB-GENE-865699 I 0.813
ENSSHAG00000004205 Sarcophilus harrisii ENSSHAG00000004205 I 0.813
Ogr04681 Ophisaurus gracilis Ogr04681 I 0.813
SNAI2 Taeniopygia guttata ENSTGUG00000010914 I 0.813
AAB34088 Xenopus laevis AAB34088 I 0.813
Pvit_15376 Pogona vitticeps Pvit_15376 I 0.813
AAK54137 Xenopus laevis AAK54137 I 0.813
Afo_R005870 Aptenodytes forsteri Afo_R005870 I 0.813
Alligator_sinensis_CCG016283.1 Alligator sinensis Alligator_sinensis_CCG016283.1 I 0.813
Aan_R012932 Calypte anna Aan_R012932 I 0.813
Brh_R006038 Buceros rhinoceros Brh_R006038 I 0.813
AAK54139 Xenopus laevis AAK54139 I 0.813
AAK54135 Xenopus tropicalis AAK54135 I 0.813
SNAI2 Pteropus vampyrus ENSPVAG00000009457 I 0.813
ENSAPLG00000003920 Anas platyrhynchos ENSAPLG00000003920 I 0.813
SNAI2 Anolis carolinensis ENSACAG00000012332 I 0.813
SNAI2 Monodelphis domestica ENSMODG00000010173 I 0.813
SNAI2 Meleagris gallopavo ENSMGAG00000010813 I 0.813
SNAI2 Ornithorhynchus anatinus ENSOANG00000007267 I 0.813
ENSFALG00000005762 Ficedula albicollis ENSFALG00000005762 I 0.813
ENSGALG00000015241 Gallus gallus ENSGALG00000015241 I 0.813
ENSPSIG00000016395 Pelodiscus sinensis ENSPSIG00000016395 I 0.813
ENSLACG00000005413 Latimeria chalumnae ENSLACG00000005413 I 0.810
ENSMEUG00000009510 Macropus eugenii ENSMEUG00000009510 I 0.809
snai2 Gasterosteus aculeatus ENSGACG00000017935 I 0.803
ENSONIG00000009542 Oreochromis niloticus ENSONIG00000009542 I 0.801
snai2 Oryzias latipes ENSORLG00000017475 I 0.801
ENSGMOG00000002669 Gadus morhua ENSGMOG00000002669 I 0.801
ENSLOCG00000005992 Lepisosteus oculatus ENSLOCG00000005992 I 0.801
snai2 Tetraodon nigroviridis ENSTNIG00000008504 I 0.801
snai2 Takifugu rubripes ENSTRUG00000006860 I 0.801
snai2 Danio rerio ENSDARG00000040046 I 0.798
ENSPFOG00000014336 Poecilia formosa ENSPFOG00000014336 I 0.798
ENSXMAG00000019030 Xiphophorus maculatus ENSXMAG00000019030 I 0.798
ENSAMXG00000011013 Astyanax mexicanus ENSAMXG00000011013 I 0.775
ENSLACG00000004705 Latimeria chalumnae ENSLACG00000004705 I 0.774
GL26425 Drosophila persimilis FBgn0164007 I 0.769
GA17666 Drosophila pseudoobscura FBgn0077676 I 0.769
esg Drosophila melanogaster FBgn0001981 D 0.769
MDOA014024 Musca domestica MDOA014024 I 0.769
GE20968 Drosophila yakuba FBgn0238253 I 0.769
GF15382 Drosophila ananassae FBgn0092407 I 0.769
LCUP013268 Lucilia cuprina LCUP013268 I 0.769
LDEC001157 Leptinotarsa decemlineata LDEC001157 I 0.769
GG25158 Drosophila erecta FBgn0117283 I 0.769
ENSLOCG00000004887 Lepisosteus oculatus ENSLOCG00000004887 I 0.768
TC014474 Tribolium castaneum TC014474 I 0.767
GI17894 Drosophila mojavensis FBgn0140635 I 0.767
GH13754 Drosophila grimshawi FBgn0121230 I 0.767
GJ17399 Drosophila virilis FBgn0204571 I 0.767
GK18133 Drosophila willistoni FBgn0220132 I 0.767
CapteG76255 Capitella teleta CapteG76255 I 0.767
Sakowv30043351m.g Saccoglossus kowalevskii Sakowv30043351m.g I 0.766
snai1.S Xenopus laevis XB-GENE-865328 I 0.763
LotgiG114290 Lottia gigantea LotgiG114290 I 0.761
HMEL002306 Heliconius melpomene HMEL002306 I 0.760
GD24004 Drosophila simulans FBgn0195364 I 0.760
PPAI008011 Phlebotomus papatasi PPAI008011 I 0.758
snai1 Xenopus tropicalis XB-GENE-479970 I 0.758
MCINX001355 Melitaea cinxia MCINX001355 I 0.757
KGM_17970 Danaus plexippus KGM_17970 I 0.757
ENSPSIG00000003607 Pelodiscus sinensis ENSPSIG00000003607 I 0.756
Cmyd_10017446 Chelonia mydas Cmyd_10017446 I 0.756
ENSLACG00000017707 Latimeria chalumnae ENSLACG00000017707 I 0.756