myb (Danio rerio)
Myb/SANT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00249 (Myb_DNA-binding) IPR014778 ENSDARG00000053666 T269475_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including definitive hemopoiesis; hematopoietic stem cell migration; and regulation of neutrophil differentiation. Is active in chromatin. Is expressed in several structures, including head; hematopoietic cell; hematopoietic system; mesoderm; and vasculature. Orthologous to human MYB (MYB proto-oncogene, transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Myb
M00179_2.00 		Mus musculus
HAACGGHHNN
NNDDCCGTTD		 PBM
Badis et al.(2009)
Myb_1047 		0.819 0.929
MYB
M08150_2.00 		Homo sapiens
NNCAACTGHN
NDCAGTTGNN		 ChIP-seq
Mathelier et al.(2014)
MA0100.3 		0.819 0.929
MYB
M09260_2.00 		Homo sapiens
NYAACKGYYDNH
DNHRRCMGTTRN		 Misc
Kulakovskiy et al.(2013)
MYB_HUMAN.H11MO.0.A 		0.819 0.929
Myb
M09261_2.00 		Mus musculus
NYAACKGHHNBN
NVNDDCMGTTRN		 Misc
Kulakovskiy et al.(2013)
MYB_MOUSE.H11MO.0.A 		0.819 0.929
Myb
M09601_2.00 		Mus musculus
YAACBGYC
GRCVGTTR		 Misc
Heinz et al.(2010)
ERMYB-Myb_GSE22095 		0.819 0.929
MYB
M11050_2.00 		Homo sapiens
CMVNCAACBGYCNBYNBV
BVNRVNGRCVGTTGNBKG		 Transfac
Matys et al.(2006)
V$CMYB_01 		0.819 0.929
MYB
M11051_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$CMYB_Q5 		0.819 0.929
MYB
M11052_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MYB_Q3 		0.819 0.929
MYB
M11053_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MYB_Q4 		0.819 0.929
MYB
M11054_2.00 		Homo sapiens
VNNAACKDBB
VVHMGTTNNB		 Transfac
Matys et al.(2006)
V$MYB_Q6 		0.819 0.929
Mybl1
M00180_2.00 		Mus musculus
HAACBGHHN
NDDCVGTTD		 PBM
Badis et al.(2009)
Mybl1_1717 		0.753 0.843
MYBL1
M03349_2.00 		Homo sapiens
BVGTTKAACBGY
RCVGTTMAACBV		 SELEX
Jolma et al.(2013)
MYBL1_1 		0.753 0.843
MYBL1
M03350_2.00 		Homo sapiens
RMVGTTAACGGT
ACCGTTAACBKY		 SELEX
Jolma et al.(2013)
MYBL1_2 		0.753 0.843
MYBL1
M03351_2.00 		Homo sapiens
NHRACCGTTWN
NWAACGGTYDN		 SELEX
Jolma et al.(2013)
MYBL1_3 		0.753 0.843
MYBL1
M03352_2.00 		Homo sapiens
HAACSGHHHHAACBGHC
GDCVGTTDDDDCSGTTD		 SELEX
Jolma et al.(2013)
MYBL1_4 		0.753 0.843
Mybl1
M09262_2.00 		Mus musculus
BBNBYAACBGCCNSB
VSNGGCVGTTRVNVV		 Misc
Kulakovskiy et al.(2013)
MYBA_MOUSE.H11MO.0.C 		0.753 0.843
MYB_AVIMB
M11068_2.00 		Avian myeloblastosis virus
VRYAACKGNH
DNCMGTTRYB		 Transfac
Matys et al.(2006)
V$VMYB_01 		0.663 0.729
MYB_AVIMB
M11069_2.00 		Avian myeloblastosis virus
BVYAACGGH
DCCGTTRBV		 Transfac
Matys et al.(2006)
V$VMYB_02 		0.663 0.729
For this family, TFs with SR scores > 0.661 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000070207 Myb 40 86
ENSDARP00000070207 Myb 92 138
ENSDARP00000070207 Myb 144 189
ENSDARP00000070211 Myb 40 86
ENSDARP00000070211 Myb 92 138
ENSDARP00000070211 Myb 144 189

Links

Other Myb/SANT family TFs
Other Danio rerio TFs

151 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMXG00000004244 Astyanax mexicanus ENSAMXG00000004244 I 0.903
ENSLOCG00000016218 Lepisosteus oculatus ENSLOCG00000016218 I 0.853
myb Tetraodon nigroviridis ENSTNIG00000016319 I 0.847
myb Takifugu rubripes ENSTRUG00000016069 I 0.847
ENSXMAG00000004392 Xiphophorus maculatus ENSXMAG00000004392 I 0.834
ENSPFOG00000011241 Poecilia formosa ENSPFOG00000011241 I 0.834
myb Oryzias latipes ENSORLG00000016573 I 0.834
myb Xenopus tropicalis XB-GENE-867553 I 0.833
XP_002935855 Xenopus tropicalis XP_002935855 I 0.833
ENSLACG00000002813 Latimeria chalumnae ENSLACG00000002813 I 0.833
MYB Gallus gallus ENSGALG00000013956 I 0.833
Brh_R005747 Buceros rhinoceros Brh_R005747 I 0.830
MYB Anolis carolinensis ENSACAG00000009861 I 0.830
MYB Meleagris gallopavo ENSMGAG00000013053 I 0.830
Tal_R007653 Tyto alba Tal_R007653 I 0.830
ENSFALG00000011914 Ficedula albicollis ENSFALG00000011914 I 0.830
Afo_R014904 Aptenodytes forsteri Afo_R014904 I 0.830
ENSPSIG00000011892 Pelodiscus sinensis ENSPSIG00000011892 I 0.830
Pvit_17294 Pogona vitticeps Pvit_17294 I 0.830
Aan_R009776 Calypte anna Aan_R009776 I 0.830
Alligator_sinensis_CCG012608.1 Alligator sinensis Alligator_sinensis_CCG012608.1 I 0.830
ENSAPLG00000007728 Anas platyrhynchos ENSAPLG00000007728 I 0.830
MYB Taeniopygia guttata ENSTGUG00000011495 I 0.830
Cmyd_10011933 Chelonia mydas Cmyd_10011933 I 0.830
Gfo_R006432 Geospiza fortis Gfo_R006432 I 0.826
MYB Callithrix jacchus ENSCJAG00000007798 I 0.825
MYB Ornithorhynchus anatinus ENSOANG00000002777 I 0.825
MYB Monodelphis domestica ENSMODG00000017488 I 0.825
ENSSHAG00000014728 Sarcophilus harrisii ENSSHAG00000014728 I 0.825
ENSONIG00000000469 Oreochromis niloticus ENSONIG00000000469 I 0.824
Myb Mus musculus ENSMUSG00000019982 D 0.819
Myotis_brandtii_MYB_10035701 Myotis brandtii Myotis_brandtii_MYB_10035701 I 0.819
ENSNLEG00000014751 Nomascus leucogenys ENSNLEG00000014751 I 0.819
MYB Microcebus murinus ENSMICG00000005531 I 0.819
ENSSTOG00000007581 Ictidomys tridecemlineatus ENSSTOG00000007581 I 0.819
ENSTSYG00000014301 Tarsius syrichta ENSTSYG00000014301 I 0.819
MYB Myotis lucifugus ENSMLUG00000002125 I 0.819
ENSAMEG00000009813 Ailuropoda melanoleuca ENSAMEG00000009813 I 0.819
MYB Oryctolagus cuniculus ENSOCUG00000011633 I 0.819
MYB Pan troglodytes ENSPTRG00000018631 I 0.819
ENSPANG00000018932 Papio anubis ENSPANG00000018932 I 0.819
MYB Procavia capensis ENSPCAG00000009197 I 0.819
MYB Tursiops truncatus ENSTTRG00000003718 I 0.819
MYB Pteropus vampyrus ENSPVAG00000007652 I 0.819
MYB Sorex araneus ENSSARG00000002855 I 0.819
ENSOARG00000014901 Ovis aries ENSOARG00000014901 I 0.819
MYB Otolemur garnettii ENSOGAG00000000056 I 0.819
MYB Ochotona princeps ENSOPRG00000013639 I 0.819
MYB Sus scrofa ENSSSCG00000004167 I 0.819
MYB Macaca mulatta ENSMMUG00000018166 I 0.819
MYB Dasypus novemcinctus ENSDNOG00000047370 I 0.819
MYB Erinaceus europaeus ENSEEUG00000001468 I 0.819
MYB Felis catus ENSFCAG00000001812 I 0.819
MYB Homo sapiens ENSG00000118513 D 0.819
ENSCSAG00000016815 Chlorocebus sabaeus ENSCSAG00000016815 I 0.819
MYB Cavia porcellus ENSCPOG00000014607 I 0.819
MYB Bos taurus ENSBTAG00000012074 I 0.819
MYB Canis familiaris ENSCAFG00000000230 I 0.819
MYB Choloepus hoffmanni ENSCHOG00000010472 I 0.819
ENSP00000339992-D1 Bos grunniens ENSP00000339992-D1 I 0.819
MYB Equus caballus ENSECAG00000009918 I 0.819
ENSP00000339992 Macaca fascicularis ENSP00000339992 I 0.819
MYB Loxodonta africana ENSLAFG00000018350 I 0.819
ENSMPUG00000014814 Mustela putorius furo ENSMPUG00000014814 I 0.816
myb Gasterosteus aculeatus ENSGACG00000011054 I 0.811
MYB Tupaia belangeri ENSTBEG00000016454 I 0.803
Myb Rattus norvegicus ENSRNOG00000055858 I 0.802
ENSPPYG00000017028 Pongo abelii ENSPPYG00000017028 I 0.787
Ogr08782 Ophisaurus gracilis Ogr08782 I 0.786
ENSGMOG00000011856 Gadus morhua ENSGMOG00000011856 I 0.785
myb.S Xenopus laevis XB-GENE-867566 I 0.785
ENSLACG00000011097 Latimeria chalumnae ENSLACG00000011097 I 0.778
Alligator_sinensis_CCG001232.1 Alligator sinensis Alligator_sinensis_CCG001232.1 I 0.759
Pvit_15001 Pogona vitticeps Pvit_15001 I 0.759
MYBL1 Anolis carolinensis ENSACAG00000016577 I 0.759
Ogr00471 Ophisaurus gracilis Ogr00471 I 0.757
MYBL1 Cavia porcellus ENSCPOG00000007578 I 0.753
ENSSHAG00000010559 Sarcophilus harrisii ENSSHAG00000010559 I 0.753
MYBL1 Sorex araneus ENSSARG00000006938 I 0.753
MYBL1 Macaca mulatta ENSMMUG00000013974 I 0.753
MYBL1 Callithrix jacchus ENSCJAG00000004466 I 0.753
MYBL1 Ornithorhynchus anatinus ENSOANG00000002308 I 0.753
Mybl1 Mus musculus ENSMUSG00000025912 D 0.753
Myotis_brandtii_MYBL1_10031628 Myotis brandtii Myotis_brandtii_MYBL1_10031628 I 0.753
MYBL1 Canis familiaris ENSCAFG00000007344 I 0.753
Mybl1 Rattus norvegicus ENSRNOG00000021669 I 0.753
MYBL1 Myotis lucifugus ENSMLUG00000003166 I 0.753
ENSAMEG00000012401 Ailuropoda melanoleuca ENSAMEG00000012401 I 0.753
ENSSTOG00000006634 Ictidomys tridecemlineatus ENSSTOG00000006634 I 0.753
MYBL1 Loxodonta africana ENSLAFG00000004821 I 0.753
MYBL1 Equus caballus ENSECAG00000015959 I 0.753
ENSP00000385360 Macaca fascicularis ENSP00000385360 I 0.753
MYBL1 Oryctolagus cuniculus ENSOCUG00000015184 I 0.753
MYBL1 Felis catus ENSFCAG00000031398 I 0.753
MYBL1 Otolemur garnettii ENSOGAG00000004344 I 0.753
MYBL1 Homo sapiens ENSG00000185697 D 0.753
MYBL1 Vicugna pacos ENSVPAG00000004194 I 0.753
MYBL1 Tursiops truncatus ENSTTRG00000017138 I 0.753
ENSPSIG00000011935 Pelodiscus sinensis ENSPSIG00000011935 I 0.753
MYBL1 Pan troglodytes ENSPTRG00000020308 I 0.753
MYBL1 Dasypus novemcinctus ENSDNOG00000016860 I 0.753
ENSPPYG00000018640 Pongo abelii ENSPPYG00000018640 I 0.753
MYBL1 Monodelphis domestica ENSMODG00000007964 I 0.753
MYBL1 Gorilla gorilla ENSGGOG00000003892 I 0.753
ENSCSAG00000014195 Chlorocebus sabaeus ENSCSAG00000014195 I 0.753
ENSOARG00000017663 Ovis aries ENSOARG00000017663 I 0.751
MYBL1 Taeniopygia guttata ENSTGUG00000011289 I 0.750
ENSFALG00000005444 Ficedula albicollis ENSFALG00000005444 I 0.750
Gfo_R002003 Geospiza fortis Gfo_R002003 I 0.750
estExt_fgenesh2_pg.C_1220082 Branchiostoma floridae estExt_fgenesh2_pg.C_1220082 I 0.748
estExt_fgenesh2_pg.C_1220090 Branchiostoma floridae estExt_fgenesh2_pg.C_1220090 I 0.748
ENSAPLG00000014596 Anas platyrhynchos ENSAPLG00000014596 I 0.743
Afo_R010364 Aptenodytes forsteri Afo_R010364 I 0.743
ENSGALG00000015522 Gallus gallus ENSGALG00000015522 I 0.743
Aan_R014924 Calypte anna Aan_R014924 I 0.743
MYBL1 Echinops telfairi ENSETEG00000009840 I 0.737
MYB Gorilla gorilla ENSGGOG00000001379 I 0.728
Tal_R003498 Tyto alba Tal_R003498 I 0.727
Brh_R006445 Buceros rhinoceros Brh_R006445 I 0.727
ENSPMAG00000000117 Petromyzon marinus ENSPMAG00000000117 I 0.727
ENSLOCG00000004709 Lepisosteus oculatus ENSLOCG00000004709 I 0.720
mybl1 Xenopus tropicalis XB-GENE-986560 I 0.720
ENSPMAG00000001639 Petromyzon marinus ENSPMAG00000001639 I 0.720
mybl1 Danio rerio ENSDARG00000030999 I 0.715
ENSPFOG00000005169 Poecilia formosa ENSPFOG00000005169 I 0.710
ENSXMAG00000001658 Xiphophorus maculatus ENSXMAG00000001658 I 0.710
mybl1 Oryzias latipes ENSORLG00000008488 I 0.710
mybl1 Takifugu rubripes ENSTRUG00000008816 I 0.699
mybl1 Tetraodon nigroviridis ENSTNIG00000010104 I 0.694
mybl1 Gasterosteus aculeatus ENSGACG00000002964 I 0.692
NEMVEDRAFT_v1g38726 Nematostella vectensis NEMVEDRAFT_v1g38726 I 0.689
ENSONIG00000014188 Oreochromis niloticus ENSONIG00000014188 I 0.685
ENSAMXG00000013759 Astyanax mexicanus ENSAMXG00000013759 I 0.683
mybl1.L Xenopus laevis XB-GENE-986561 I 0.678
SMAR001262 Strigamia maritima SMAR001262 I 0.677
Sakowv30034766m.g Saccoglossus kowalevskii Sakowv30034766m.g I 0.674
mybl2b Danio rerio ENSDARG00000032264 I 0.674
Brh_R006404 Buceros rhinoceros Brh_R006404 I 0.665
ENSAPLG00000005213 Anas platyrhynchos ENSAPLG00000005213 I 0.664
ENSGMOG00000017106 Gadus morhua ENSGMOG00000017106 I 0.664
MYBL2 Gallus gallus ENSGALG00000003503 I 0.664
Tal_R007942 Tyto alba Tal_R007942 I 0.664
ENSTGUG00000004426 Taeniopygia guttata ENSTGUG00000004426 I 0.664
Gfo_R005427 Geospiza fortis Gfo_R005427 I 0.664
Aan_R003280 Calypte anna Aan_R003280 I 0.664
MYBL2 Meleagris gallopavo ENSMGAG00000002972 I 0.664
Afo_R009791 Aptenodytes forsteri Afo_R009791 I 0.664
MYB_AVIMB Avian myeloblastosis virus MYB_AVIMB D 0.663
ENSLACG00000018995 Latimeria chalumnae ENSLACG00000018995 I 0.663
ENSPANG00000008051 Papio anubis ENSPANG00000008051 I 0.661