ENSCAFG00000031316 (Canis familiaris)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCAFG00000031316 T207721_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nkx2-1
M00385_2.00 		Mus musculus
NNRAGDRN
NYHCTYNN		 PBM
Berger et al.(2008)
Titf1_1722 		0.867 1.000
Nkx2-4
M00514_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-4_3074 		0.867 1.000
NKX2-1
M09146_2.00 		Homo sapiens
BTKGAGWGBN
NVCWCTCMAV		 Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A 		0.867 1.000
Nkx2-1
M09171_2.00 		Mus musculus
NBTKGAGWGB
VCWCTCMAVN		 Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A 		0.867 1.000
Nkx2-1
M09563_2.00 		Mus musculus
BTBRAGWGBH
DVCWCTYVAV		 Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252 		0.867 1.000
NKX2-1
M10694_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TITF1_Q3 		0.867 1.000
NKX2-1
M10695_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5_01 		0.867 1.000
NKX2-1
M10696_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5 		0.867 1.000
NKX2-1
M10697_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q6 		0.867 1.000
ceh-24
M02181_2.00 		Caenorhabditis elegans
NNRAKWRNN
NNYWMTYNN		 PBM
Weirauch et al.(2014)
pTH6327 		0.837 0.877
scro
M03854_2.00 		Drosophila melanogaster
NNBRMGTGB
VCACKYVNN		 SELEX
Nitta et al.(2015)
scro_1 		0.834 0.930
Nkx2-2
M00438_2.00 		Mus musculus
NNNRAGDRN
NYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-2_2823 		0.798 0.895
Nkx2-2
M09190_2.00 		Mus musculus
NTBRAGWGBBN
NVVCWCTYVAN		 Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A 		0.798 0.895
NKX2-2
M10681_2.00 		Homo sapiens
WTAAGTRBTT
AAVYACTTAW		 Transfac
Matys et al.(2006)
V$NKX22_01 		0.798 0.895
NKX2-2
M10682_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3_01 		0.798 0.895
NKX2-2
M10683_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3 		0.798 0.895
NKX2-5
M00323_2.00 		Homo sapiens
NWYAAGTGSNN
NNSCACTTRWN		 PBM
Barrera et al.(2016)
NKX2-5_REF 		0.787 0.825
Nkx2-5
M00404_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-5_3436 		0.787 0.825
NKX2-5
M05346_2.00 		Homo sapiens
BHYAAGTGBN
NVCACTTRDV		 SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX 		0.787 0.825
Nkx2-5
M02686_2.00 		Mus musculus
WTAAKWK
MWMTTAW		 SELEX
Mathelier et al.(2014)
MA0063.1 		0.787 0.825
Nkx2-5
M08136_2.00 		Mus musculus
SYTGAGWGSYH
DRSCWCTCARS		 ChIP-seq
Mathelier et al.(2014)
MA0503.1 		0.787 0.825
NKX2-5
M09163_2.00 		Homo sapiens
BKRAGWGV
BCWCTYMV		 Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B 		0.787 0.825
Nkx2-5
M09177_2.00 		Mus musculus
NBYBRAGTGS
SCACTYVRVN		 Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A 		0.787 0.825
Nkx2-5
M09567_2.00 		Mus musculus
HBRAGWGBNN
NNVCWCTYVD		 Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529 		0.787 0.825
NKX2-5
M10742_2.00 		Homo sapiens
TYAAGTG
CACTTRA		 Transfac
Matys et al.(2006)
V$NKX25_01 		0.787 0.825
NKX2-5
M10743_2.00 		Homo sapiens
CWTAATTV
BAATTAWG		 Transfac
Matys et al.(2006)
V$NKX25_02 		0.787 0.825
NKX2-5
M10744_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q5 		0.787 0.825
NKX2-5
M10745_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q6 		0.787 0.825
NKX2-5
M00321_2.00 		Homo sapiens
HNAAGTRBNN
NNVYACTTND		 PBM
Barrera et al.(2016)
NKX2-5_R161P 		0.787 0.825
NKX2-5
M05347_2.00 		Homo sapiens
BTYAAGTGGN
NCCACTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1 		0.787 0.825
NKX2-5
M05348_2.00 		Homo sapiens
BTYAACGAB
VTCGTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2 		0.787 0.825
NKX2-5
M00322_2.00 		Homo sapiens
NNNRNNN
NNNYNNN		 PBM
Barrera et al.(2016)
NKX2-5_R190C 		0.787 0.807
NKX2-5
M00324_2.00 		Homo sapiens
NHNNNNN
NNNNNDN		 PBM
Barrera et al.(2016)
NKX2-5_T178M 		0.787 0.807
Nkx2-3
M00497_2.00 		Mus musculus
NNRAGDRNN
NNYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-3_3435 		0.785 0.842
NKX2-3
M05042_2.00 		Homo sapiens
NNBAAGTGBN
NVCACTTVNN		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX 		0.785 0.842
NKX2-3
M05045_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX 		0.785 0.842
NKX2-3
M05043_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1 		0.785 0.842
NKX2-3
M05044_2.00 		Homo sapiens
SDYAACGHB
VDCGTTRHS		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2 		0.785 0.842
NKX2-3
M05046_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1 		0.785 0.842
NKX2-3
M05047_2.00 		Homo sapiens
SWYAACSHB
VDSGTTRWS		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2 		0.785 0.842
vnd
M06551_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Mathelier et al.(2014)
MA0253.1 		0.782 0.860
vnd
M06377_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986 		0.782 0.860
vnd
M06378_2.00 		Drosophila melanogaster
KYTSAAGWGY
RCWCTTSARM		 B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986 		0.782 0.860
vnd
M06379_2.00 		Drosophila melanogaster
BTBAAGTR
YACTTVAV		 B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986 		0.782 0.860
vnd
M09683_2.00 		Drosophila melanogaster
TCAAGTGB
VCACTTGA		 Misc
Kulakovskiy et al.(2009)
vnd 		0.782 0.860
ceh-28
M08210_2.00 		Caenorhabditis elegans
AATCGATW
WATCGATT		 ChIP-seq
Contrino et al.(2012)
Mw138 		0.781 0.684
Nkx2-9
M00520_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-9_3082 		0.775 0.807
Nkx2-9
M00800_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Weirauch et al.(2013)
pTH2842 		0.775 0.807
Nkx2-9
M09215_2.00 		Mus musculus
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C 		0.775 0.807
tin
M00559_2.00 		Drosophila melanogaster
NWYAAGTGGNN
NNCCACTTRWN		 PBM
Busser et al.(2012a)
Tin 		0.771 0.667
tin
M03809_2.00 		Drosophila melanogaster
BTYAAGTGSN
NSCACTTRAV		 SELEX
Nitta et al.(2015)
tin_1 		0.771 0.667
tin
M06284_2.00 		Drosophila melanogaster
BTYAAGTG
CACTTRAV		 B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110 		0.771 0.667
tin
M06285_2.00 		Drosophila melanogaster
BCTCAAGTGSVN
NBSCACTTGAGV		 B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110 		0.771 0.667
tin
M06286_2.00 		Drosophila melanogaster
BWYAAGTR
YACTTRWV		 B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110 		0.771 0.667
tin
M08421_2.00 		Drosophila melanogaster
DBTCRAGTGS
SCACTYGAVH		 ChIP-chip
Mathelier et al.(2014)
MA0247.2 		0.771 0.667
Nkx2-6
M00496_2.00 		Mus musculus
HYAAGTRBNN
NNVYACTTRD		 PBM
Berger et al.(2008)
Nkx2-6_3437 		0.763 0.789
ceh-22
M00376_2.00 		Caenorhabditis elegans
WBRAGTRBNN
NNVYACTYVW		 PBM
Berger et al.(2006)
Ceh-22 		0.761 0.807
NKX2-5
M00320_2.00 		Homo sapiens
NHBAAKWRN
NYWMTTVDN		 PBM
Barrera et al.(2016)
NKX2-5_K183E 		0.754 0.807
NKX2-8
M00302_2.00 		Homo sapiens
NNRAGDRB
VYHCTYNN		 PBM
Barrera et al.(2016)
NKX2-8_REF 		0.743 0.807
NKX2-8
M05149_2.00 		Homo sapiens
BTSRAGTGBN
NVCACTYSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX 		0.743 0.807
NKX2-8
M09145_2.00 		Homo sapiens
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C 		0.743 0.807
NKX2-8
M05150_2.00 		Homo sapiens
GCARTAACGACATC
GATGTCGTTAYTGC		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1 		0.743 0.807
NKX2-8
M05151_2.00 		Homo sapiens
BTSAAGTGBN
NVCACTTSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2 		0.743 0.807
NKX2-8
M05152_2.00 		Homo sapiens
BTBAACGAB
VTCGTTVAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3 		0.743 0.807
NKX2-8
M00301_2.00 		Homo sapiens
NNRAKDRB
VYHMTYNN		 PBM
Barrera et al.(2016)
NKX2-8_A94T 		0.743 0.789
Q24782_9CNID
M02206_2.00 		Eleutheria dichotoma
TTAATTAA
TTAATTAA		 PBM
Weirauch et al.(2014)
pTH5486 		0.600 0.474
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCAFP00000037150 Homeodomain 40 96

Links

Other Homeodomain family TFs
Other Canis familiaris TFs

832 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
67303 Aureococcus anophagefferens 67303 N
AAEL000771 Aedes aegypti AAEL000771 N
AALB009867 Anopheles albimanus AALB009867 N
Aan_R006397 Calypte anna Aan_R006397 N
AATE016483 Anopheles atroparvus AATE016483 N
ACOM022799 Anopheles coluzzii ACOM022799 N
ACUA008827 Anopheles culicifacies ACUA008827 N
ACUA010594 Anopheles culicifacies ACUA010594 N
ACUA012732 Anopheles culicifacies ACUA012732 N
AEPI003629 Anopheles epiroticus AEPI003629 N
AEPI007652 Anopheles epiroticus AEPI007652 N
AEPI007948 Anopheles epiroticus AEPI007948 N
Afo_R012388 Aptenodytes forsteri Afo_R012388 N
AFUN006689 Anopheles funestus AFUN006689 N
AFUN009317 Anopheles funestus AFUN009317 N
AFUN010198 Anopheles funestus AFUN010198 N
AGAP028091 Anopheles gambiae AGAP028091 N
ALUE_0000245701 Ascaris lumbricoides ALUE_0000245701 N
ALUE_0000639901 Ascaris lumbricoides ALUE_0000639901 N
AMAM004028 Anopheles maculatus AMAM004028 N
AMAM023617 Anopheles maculatus AMAM023617 N
AMEC007393 Anopheles melas AMEC007393 N
AMEC011653 Anopheles melas AMEC011653 N
AMEM002834 Anopheles merus AMEM002834 N
AMIN001220 Anopheles minimus AMIN001220 N
AMIN009302 Anopheles minimus AMIN009302 N
ANCDUO_13942 Ancylostoma duodenale ANCDUO_13942 N
AQUA001261 Anopheles quadriannulatus AQUA001261 N
ASTEI06131 Anopheles stephensi ASTEI06131 N
BGIBMGA003081 Bombyx mori BGIBMGA003081 N
Cla016375 Citrullus lanatus Cla016375 N
CLEC006960 Cimex lectularius CLEC006960 N
Cmyd_10006594 Chelonia mydas Cmyd_10006594 N
CPIJ012041 Culex quinquefasciatus CPIJ012041 N
CPIJ014017 Culex quinquefasciatus CPIJ014017 N
CpipJ_CPIJ012041 Culex pipiens CpipJ_CPIJ012041 N
CpipJ_CPIJ014017 Culex pipiens CpipJ_CPIJ014017 N
DAPPUDRAFT_113704 Daphnia pulex DAPPUDRAFT_113704 N
DDB_G0287073 Dictyostelium discoideum DDB_G0287073 N
ECPE_0001383301 Echinostoma caproni ECPE_0001383301 N
ENSAMXG00000017231 Astyanax mexicanus ENSAMXG00000017231 I
ENSAPLG00000003216 Anas platyrhynchos ENSAPLG00000003216 N
ENSAPLG00000010204 Anas platyrhynchos ENSAPLG00000010204 N
ENSAPLG00000013168 Anas platyrhynchos ENSAPLG00000013168 I
ENSBTAP00000027633-D1 Bos grunniens ENSBTAP00000027633-D1 I
SOX8 Callithrix jacchus ENSCJAG00000002684 I
ENSCSAG00000016751 Chlorocebus sabaeus ENSCSAG00000016751 N
SOX18 Dasypus novemcinctus ENSDNOG00000036237 N
SOX18 Echinops telfairi ENSETEG00000001816 N
SOX10 Echinops telfairi ENSETEG00000012633 I
SOX8 Echinops telfairi ENSETEG00000015470 N
SOX9 Echinops telfairi ENSETEG00000020237 I
ENSFALG00000011068 Ficedula albicollis ENSFALG00000011068 N
SOX8 Felis catus ENSFCAG00000004219 N
ENSFCAG00000015685 Felis catus ENSFCAG00000015685 I
SOX2 Felis catus ENSFCAG00000029205 I
ENSMGAG00000006624 Meleagris gallopavo ENSMGAG00000006624 N
SOX8 Microcebus murinus ENSMICG00000011516 I
SOX9 Myotis lucifugus ENSMLUG00000030312 I
Hmg20b Mus musculus ENSMUSG00000020232 D
Sox17 Mus musculus ENSMUSG00000025902 D
ENSNLEG00000002693 Nomascus leucogenys ENSNLEG00000002693 N
ENSOANG00000011188 Ornithorhynchus anatinus ENSOANG00000011188 I
SOX9 Ochotona princeps ENSOPRG00000007860 N
ENSP00000409273 Macaca fascicularis ENSP00000409273 I
SOX2 Procavia capensis ENSPCAG00000003690 I
ENSPCAG00000014137 Procavia capensis ENSPCAG00000014137 N
SOX18 Procavia capensis ENSPCAG00000015663 N
ENSPMAG00000004519 Petromyzon marinus ENSPMAG00000004519 N
ENSPSIG00000016857 Pelodiscus sinensis ENSPSIG00000016857 N
SOX18 Pan troglodytes ENSPTRG00000030459 I
BBX Sorex araneus ENSSARG00000008353 N
SOX17 Sorex araneus ENSSARG00000009573 I
ENSSHAG00000008406 Sarcophilus harrisii ENSSHAG00000008406 I
SOX9 Tupaia belangeri ENSTBEG00000000175 N
sox9a Tetraodon nigroviridis ENSTNIG00000001901 N
ENSTSYG00000001164 Tarsius syrichta ENSTSYG00000001164 I
ENSTSYG00000006321 Tarsius syrichta ENSTSYG00000006321 I
LEF1 Tursiops truncatus ENSTTRG00000008109 N
ENSTTRG00000015548 Tursiops truncatus ENSTTRG00000015548 I
TCF7L2 Vicugna pacos ENSVPAG00000008158 N
ENSVPAG00000008729 Vicugna pacos ENSVPAG00000008729 N
estExt_fgeneshDP_kg.C_1020010 Dictyostelium purpureum estExt_fgeneshDP_kg.C_1020010 N
F443_09320 Phytophthora parasitica F443_09320 N
fgenesh1_pm.C_scaffold_23000166 Phytophthora capsici fgenesh1_pm.C_scaffold_23000166 N
fgenesh_scip_prom.28083.3150 Phytophthora lateralis fgenesh_scip_prom.28083.3150 N
Gfo_R008143 Geospiza fortis Gfo_R008143 N
GLOINDRAFT_335861 Rhizophagus irregularis GLOINDRAFT_335861 N
Gorai.005G106800 Gossypium raimondii Gorai.005G106800 N
HelroG68905 Helobdella robusta HelroG68905 N
HHAL000218-PA Halyomorpha halys HHAL000218-PA N
HMEL013676 Heliconius melpomene HMEL013676 N
HmN_000301900 Hymenolepis microstoma HmN_000301900 N
ISCW001638 Ixodes scapularis ISCW001638 N
JL09_g5343 Pichia kudriavzevii JL09_g5343 N
L798_00185 Zootermopsis nevadensis L798_00185 N
L798_12046 Zootermopsis nevadensis L798_12046 N
L898_g4879 Steinernema monticolum L898_g4879 N
LDEC017494 Leptinotarsa decemlineata LDEC017494 N
LDEC018263 Leptinotarsa decemlineata LDEC018263 N
LotgiG143673 Lottia gigantea LotgiG143673 N
M422DRAFT_54734 Sphaerobolus stellatus M422DRAFT_54734 N
MESCA006364 Megaselia scalaris MESCA006364 N
Minc18937 Meloidogyne incognita Minc18937 N
MPER_06248 Moniliophthora perniciosa MPER_06248 N
Myotis_brandtii_Hmgb2_10029741 Myotis brandtii Myotis_brandtii_Hmgb2_10029741 N
Myotis_brandtii_TIMM8A_10019481 Myotis brandtii Myotis_brandtii_TIMM8A_10019481 N
OESDEN_19415 Oesophagostomum dentatum OESDEN_19415 N
Ogr00751 Ophisaurus gracilis Ogr00751 I
Ogr11176 Ophisaurus gracilis Ogr11176 N
Ogr13852 Ophisaurus gracilis Ogr13852 N
PEQ_0000549401 Parascaris equorum PEQ_0000549401 N
PHUM433280 Pediculus humanus PHUM433280 N
Phyra76615 Phytophthora ramorum Phyra76615 N
Physo127875 Phytophthora sojae Physo127875 N
PK00252.1 Cannabis sativa PK00252.1 N
PredSwiss_ASS2010_3779.1 Pneumocystis carinii PredSwiss_ASS2010_3779.1 N
PredSwiss_CON1835.1 Pneumocystis carinii PredSwiss_CON1835.1 N
SINV16572 Solenopsis invicta SINV16572 N
SMAR007058 Strigamia maritima SMAR007058 N
TC009856 Tribolium castaneum TC009856 N
TcIL3000.10.440 Trypanosoma congolense TcIL3000.10.440 N
TCNE_0000669501 Toxocara canis TCNE_0000669501 N
TVAG_114290 Trichomonas vaginalis TVAG_114290 N
WUBG_12101 Wuchereria bancrofti WUBG_12101 N
YQE_03817 Dendroctonus ponderosae YQE_03817 N