PAX6 (Sorex araneus)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSSARG00000011424 T237488_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		1.000 1.000
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		1.000 1.000
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		1.000 1.000
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		1.000 1.000
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		1.000 1.000
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		1.000 1.000
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		1.000 1.000
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		1.000 1.000
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		1.000 1.000
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		1.000 1.000
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		1.000 1.000
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		1.000 1.000
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		1.000 1.000
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		1.000 1.000
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.994 0.994
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.994 0.994
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.994 0.994
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.994 0.994
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.994 0.994
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.994 0.994
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.994 0.994
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.931 0.931
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.931 0.931
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.931 0.931
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.902 0.902
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.902 0.902
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.902 0.902
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSSARP00000010317 Paired box 4 139
ENSSARP00000010317 Homeodomain 225 281

Links

Other Homeodomain,Paired box family TFs
Other Sorex araneus TFs

194 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 1.000
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 1.000
PAX6 Homo sapiens ENSG00000007372 D 1.000
PAX6 Gallus gallus ENSGALG00000012123 I 1.000
Pax6 Rattus norvegicus ENSRNOG00000004410 I 1.000
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 1.000
PAX6 Bos taurus ENSBTAG00000004561 I 1.000
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 1.000
PAX6 Callithrix jacchus ENSCJAG00000005942 I 1.000
PAX6 Gorilla gorilla ENSGGOG00000010246 I 1.000
PAX6 Microcebus murinus ENSMICG00000004089 I 1.000
PAX6 Procavia capensis ENSPCAG00000005165 I 1.000
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 1.000
PAX6 Otolemur garnettii ENSOGAG00000007857 I 1.000
PAX6 Ochotona princeps ENSOPRG00000001678 I 1.000
Pax6 Mus musculus ENSMUSG00000027168 D 1.000
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 1.000
PAX6 Myotis lucifugus ENSMLUG00000006517 I 1.000
PAX6 Macaca mulatta ENSMMUG00000016810 I 1.000
PAX6 Monodelphis domestica ENSMODG00000009611 I 1.000
PAX6 Sus scrofa ENSSSCG00000013320 I 1.000
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 1.000
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 1.000
Pvit_09512 Pogona vitticeps Pvit_09512 I 1.000
PAX6 Anolis carolinensis ENSACAG00000002252 I 1.000
pax6 Xenopus tropicalis XB-GENE-484088 I 1.000
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.994
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.994
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.994
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.994
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.994
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.994
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.994
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.994
PAX6 Felis catus ENSFCAG00000007094 I 0.994
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.994
pax6a Danio rerio ENSDARG00000103379 I 0.994
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.994
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.994
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.994
PAX6 Equus caballus ENSECAG00000021000 I 0.994
pax6b Danio rerio ENSDARG00000045936 I 0.994
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.988
pax6.S Xenopus laevis XB-GENE-6464331 I 0.988
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.988
PAX6 Echinops telfairi ENSETEG00000002655 I 0.988
pax6b Oryzias latipes ENSORLG00000009913 I 0.988
pax6.L Xenopus laevis XB-GENE-865046 I 0.988
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.988
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.983
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.983
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.983
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.977
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.977
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.971
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.971
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.965
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.960
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.954
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.954
L798_11483 Zootermopsis nevadensis L798_11483 I 0.948
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.942
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.942
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.942
GK13702 Drosophila willistoni FBgn0215710 I 0.936
ey Drosophila pseudoobscura FBgn0018538 I 0.936
GF22818 Drosophila ananassae FBgn0099812 I 0.936
ey Drosophila persimilis FBgn0043659 I 0.936
TC008176 Tribolium castaneum TC008176 I 0.936
GI14081 Drosophila mojavensis FBgn0136835 I 0.936
SMAR013763 Strigamia maritima SMAR013763 I 0.936
GB50342 Apis mellifera GB50342 I 0.931
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.931
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.931
ey Drosophila melanogaster FBgn0005558 D 0.931
GE14559 Drosophila yakuba FBgn0232158 I 0.931
NV15820 Nasonia vitripennis NV15820 I 0.931
ey Drosophila virilis FBgn0028754 I 0.931
GG16399 Drosophila erecta FBgn0108631 I 0.931
ey Drosophila sechellia FBgn0068720 I 0.931
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.925
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.925
HelroG80374 Helobdella robusta HelroG80374 I 0.925
L798_00712 Zootermopsis nevadensis L798_00712 I 0.925
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.919
TC007409 Tribolium castaneum TC007409 I 0.913
GB41504 Apis mellifera GB41504 I 0.913
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.913
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.913
NV17076 Nasonia vitripennis NV17076 I 0.913
GJ13300 Drosophila virilis FBgn0200526 I 0.908
GK13683 Drosophila willistoni FBgn0215691 I 0.908
LotgiG133720 Lottia gigantea LotgiG133720 I 0.908
ISCW021772 Ixodes scapularis ISCW021772 I 0.908
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.908
GH23963 Drosophila grimshawi FBgn0131420 I 0.908
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.908
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.908
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.908
GI14042 Drosophila mojavensis FBgn0136796 I 0.908
GL17563 Drosophila persimilis FBgn0155166 I 0.908
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.908
GE14563 Drosophila yakuba FBgn0232162 I 0.902
GG16402 Drosophila erecta FBgn0108634 I 0.902
GF21877 Drosophila ananassae FBgn0098877 I 0.902
GM13021 Drosophila sechellia FBgn0167952 I 0.902
toy Drosophila melanogaster FBgn0019650 D 0.902
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.896
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.896
D918_01592 Trichuris suis D918_01592 I 0.890
PHUM097050 Pediculus humanus PHUM097050 I 0.879
ISCW006352 Ixodes scapularis ISCW006352 I 0.879
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.873
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.861
D915_07175 Fasciola hepatica D915_07175 I 0.861
AALB006354 Anopheles albimanus AALB006354 I 0.861
ACUA021227 Anopheles culicifacies ACUA021227 I 0.855
AFUN011575 Anopheles funestus AFUN011575 I 0.855
AGAP000063 Anopheles gambiae AGAP000063 I 0.855
AEPI005803 Anopheles epiroticus AEPI005803 I 0.855
AARA001115 Anopheles arabiensis AARA001115 I 0.855
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.855
ASIS012967 Anopheles sinensis ASIS012967 I 0.855
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.855
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.855
AMIN002127 Anopheles minimus AMIN002127 I 0.855
L892_g3713 Steinernema scapterisci L892_g3713 I 0.855
AMEC021831 Anopheles melas AMEC021831 I 0.855
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.850
ASIS012617 Anopheles sinensis ASIS012617 I 0.850
MCINX016249 Melitaea cinxia MCINX016249 I 0.850
CBN04513 Caenorhabditis brenneri CBN04513 I 0.844
CRE07226 Caenorhabditis remanei CRE07226 I 0.844
ACUA016154 Anopheles culicifacies ACUA016154 I 0.844
AALB006643 Anopheles albimanus AALB006643 I 0.844
AAEL002321 Aedes aegypti AAEL002321 I 0.844
T265_09221 Opisthorchis viverrini T265_09221 I 0.844
A_05170 Schistosoma haematobium A_05170 I 0.838
ADIR000973 Anopheles dirus ADIR000973 I 0.838
AEPI005798 Anopheles epiroticus AEPI005798 I 0.838
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.838
AFUN011570 Anopheles funestus AFUN011570 I 0.838
AMEM002691 Anopheles merus AMEM002691 I 0.838
AFAF017899 Anopheles farauti AFAF017899 I 0.838
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.838
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.838
AMIN002132 Anopheles minimus AMIN002132 I 0.838
AMEC013051 Anopheles melas AMEC013051 I 0.838
GD24416 Drosophila simulans FBgn0195753 I 0.838
AGAP000067 Anopheles gambiae AGAP000067 I 0.838
HelroG173449 Helobdella robusta HelroG173449 I 0.838
ACHR009845 Anopheles christyi ACHR009845 I 0.838
AARA001110 Anopheles arabiensis AARA001110 I 0.838
Smp_160670 Schistosoma mansoni Smp_160670 I 0.838
AATE014626 Anopheles atroparvus AATE014626 I 0.838
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.832
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.832
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.832
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.827
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.827
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.827
vab-3 Caenorhabditis elegans WBGene00006870 I 0.827
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.821
EFV57892 Trichinella spiralis EFV57892 I 0.821
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.821
Smp_170750 Schistosoma mansoni Smp_170750 I 0.821
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.815
ADAC003449 Anopheles darlingi ADAC003449 I 0.798
AFAF009619 Anopheles farauti AFAF009619 I 0.792
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.792
csin110224 Clonorchis sinensis csin110224 I 0.792
T265_14971 Opisthorchis viverrini T265_14971 I 0.786
ACHR008920 Anopheles christyi ACHR008920 I 0.786
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.775
D917_00854 Trichinella nativa D917_00854 I 0.769
ADAC001560 Anopheles darlingi ADAC001560 I 0.757
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.751
MESCA003564 Megaselia scalaris MESCA003564 I 0.746
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.746
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.746
Aan_R006618 Calypte anna Aan_R006618 I 0.746
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.746
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.746
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.746
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.746
ADIR000968 Anopheles dirus ADIR000968 I 0.743
TsM_000166900 Taenia solium TsM_000166900 I 0.740
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.740
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.734
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.728
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.723
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.723
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.718
csin101119 Clonorchis sinensis csin101119 I 0.711