SMU15027897 (Schmidtea mediterranea)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		SMU15027897 T237746_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.896 0.896
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.896 0.896
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.896 0.896
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.890 0.890
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.890 0.890
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.890 0.890
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.879 0.879
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.879 0.879
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.879 0.879
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.879 0.879
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.879 0.879
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.879 0.879
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.879 0.879
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.879 0.879
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.879 0.879
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.879 0.879
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.879 0.879
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.879 0.879
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.879 0.879
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.874 0.874
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.874 0.874
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.874 0.874
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.874 0.874
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.874 0.874
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.874 0.874
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.874 0.874
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.874 0.874
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
SMU15027897 Paired box 18 142
SMU15027897 Homeodomain 287 343

Links

Other Homeodomain,Paired box family TFs
Other Schmidtea mediterranea TFs

189 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
NV17076 Nasonia vitripennis NV17076 I 0.896
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.896
GG16402 Drosophila erecta FBgn0108634 I 0.896
GB41504 Apis mellifera GB41504 I 0.896
toy Drosophila melanogaster FBgn0019650 D 0.896
GE14563 Drosophila yakuba FBgn0232162 I 0.896
GM13021 Drosophila sechellia FBgn0167952 I 0.896
TC008176 Tribolium castaneum TC008176 I 0.896
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.896
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.896
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.896
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.890
D918_01592 Trichuris suis D918_01592 I 0.890
L798_00712 Zootermopsis nevadensis L798_00712 I 0.890
ey Drosophila melanogaster FBgn0005558 D 0.890
L798_11483 Zootermopsis nevadensis L798_11483 I 0.889
GD24416 Drosophila simulans FBgn0195753 I 0.889
GG16399 Drosophila erecta FBgn0108631 I 0.885
GF21877 Drosophila ananassae FBgn0098877 I 0.885
ey Drosophila virilis FBgn0028754 I 0.885
ey Drosophila sechellia FBgn0068720 I 0.885
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.885
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.885
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.885
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.885
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.885
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.885
GE14559 Drosophila yakuba FBgn0232158 I 0.885
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.885
TC007409 Tribolium castaneum TC007409 I 0.885
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.885
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.885
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.885
NV15820 Nasonia vitripennis NV15820 I 0.885
GB50342 Apis mellifera GB50342 I 0.885
GL17563 Drosophila persimilis FBgn0155166 I 0.885
GI14042 Drosophila mojavensis FBgn0136796 I 0.885
GJ13300 Drosophila virilis FBgn0200526 I 0.885
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.885
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.885
GH23963 Drosophila grimshawi FBgn0131420 I 0.885
GK13683 Drosophila willistoni FBgn0215691 I 0.885
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.885
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.885
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.885
PAX6 Felis catus ENSFCAG00000007094 I 0.885
pax6a Danio rerio ENSDARG00000103379 I 0.879
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.879
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.879
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.879
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.879
ey Drosophila pseudoobscura FBgn0018538 I 0.879
GI14081 Drosophila mojavensis FBgn0136835 I 0.879
ey Drosophila persimilis FBgn0043659 I 0.879
PAX6 Homo sapiens ENSG00000007372 D 0.879
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.879
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.879
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.879
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.879
pax6 Xenopus tropicalis XB-GENE-484088 I 0.879
LotgiG133720 Lottia gigantea LotgiG133720 I 0.879
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.879
PAX6 Bos taurus ENSBTAG00000004561 I 0.879
GK13702 Drosophila willistoni FBgn0215710 I 0.879
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.879
PAX6 Sus scrofa ENSSSCG00000013320 I 0.879
SMAR013763 Strigamia maritima SMAR013763 I 0.879
PAX6 Procavia capensis ENSPCAG00000005165 I 0.879
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.879
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.879
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.879
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.879
Pax6 Mus musculus ENSMUSG00000027168 D 0.879
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.879
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.879
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.879
PAX6 Gallus gallus ENSGALG00000012123 I 0.879
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.879
PAX6 Microcebus murinus ENSMICG00000004089 I 0.879
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.874
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.874
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.874
pax6b Danio rerio ENSDARG00000045936 I 0.874
pax6.S Xenopus laevis XB-GENE-6464331 I 0.874
Smp_160670 Schistosoma mansoni Smp_160670 I 0.874
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.874
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.874
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.874
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.874
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.874
pax6b Oryzias latipes ENSORLG00000009913 I 0.874
GF22818 Drosophila ananassae FBgn0099812 I 0.874
PAX6 Sorex araneus ENSSARG00000011424 I 0.873
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.868
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.868
pax6.L Xenopus laevis XB-GENE-865046 I 0.868
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.868
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.868
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.868
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.868
T265_09221 Opisthorchis viverrini T265_09221 I 0.868
ADAC001560 Anopheles darlingi ADAC001560 I 0.865
A_05170 Schistosoma haematobium A_05170 I 0.863
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.863
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.863
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.863
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.863
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.863
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.862
PAX6 Echinops telfairi ENSETEG00000002655 I 0.861
csin101119 Clonorchis sinensis csin101119 I 0.860
T265_14971 Opisthorchis viverrini T265_14971 I 0.860
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.857
PAX6 Equus caballus ENSECAG00000021000 I 0.857
ADIR000973 Anopheles dirus ADIR000973 I 0.848
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.848
AATE014626 Anopheles atroparvus AATE014626 I 0.848
AFUN011570 Anopheles funestus AFUN011570 I 0.848
AMIN002132 Anopheles minimus AMIN002132 I 0.848
ACHR009845 Anopheles christyi ACHR009845 I 0.848
PHUM097050 Pediculus humanus PHUM097050 I 0.846
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.846
D915_07175 Fasciola hepatica D915_07175 I 0.846
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.841
L892_g3713 Steinernema scapterisci L892_g3713 I 0.841
ISCW021772 Ixodes scapularis ISCW021772 I 0.841
HelroG80374 Helobdella robusta HelroG80374 I 0.835
Smp_170750 Schistosoma mansoni Smp_170750 I 0.830
EFV57892 Trichinella spiralis EFV57892 I 0.824
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.819
AALB006354 Anopheles albimanus AALB006354 I 0.819
csin110224 Clonorchis sinensis csin110224 I 0.819
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.813
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.813
AAEL002321 Aedes aegypti AAEL002321 I 0.813
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.813
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.813
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.813
ASIS012967 Anopheles sinensis ASIS012967 I 0.813
AMIN002127 Anopheles minimus AMIN002127 I 0.813
AGAP000063 Anopheles gambiae AGAP000063 I 0.813
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.813
AARA001115 Anopheles arabiensis AARA001115 I 0.813
vab-3 Caenorhabditis elegans WBGene00006870 I 0.813
CRE07226 Caenorhabditis remanei CRE07226 I 0.813
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.813
CBN04513 Caenorhabditis brenneri CBN04513 I 0.813
ASIS012617 Anopheles sinensis ASIS012617 I 0.812
AMEC021831 Anopheles melas AMEC021831 I 0.808
AFUN011575 Anopheles funestus AFUN011575 I 0.808
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.808
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.808
ADAC003449 Anopheles darlingi ADAC003449 I 0.807
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.802
ISCW006352 Ixodes scapularis ISCW006352 I 0.802
AALB006643 Anopheles albimanus AALB006643 I 0.802
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.802
ACUA016154 Anopheles culicifacies ACUA016154 I 0.802
AFAF009619 Anopheles farauti AFAF009619 I 0.801
D917_00854 Trichinella nativa D917_00854 I 0.801
HelroG173449 Helobdella robusta HelroG173449 I 0.797
AARA001110 Anopheles arabiensis AARA001110 I 0.797
AGAP000067 Anopheles gambiae AGAP000067 I 0.797
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.797
AMEC013051 Anopheles melas AMEC013051 I 0.797
AMEM002691 Anopheles merus AMEM002691 I 0.797
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.797
MCINX016249 Melitaea cinxia MCINX016249 I 0.797
AEPI005798 Anopheles epiroticus AEPI005798 I 0.797
AFAF017899 Anopheles farauti AFAF017899 I 0.797
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.790
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.789
ACUA021227 Anopheles culicifacies ACUA021227 I 0.780
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.775
AEPI005803 Anopheles epiroticus AEPI005803 I 0.775
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.775
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.769
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.758
ACHR008920 Anopheles christyi ACHR008920 I 0.747
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.742
ADIR000968 Anopheles dirus ADIR000968 I 0.738
TsM_000166900 Taenia solium TsM_000166900 I 0.736
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.736
MESCA003564 Megaselia scalaris MESCA003564 I 0.731
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.725
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.720
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.714
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.708
Sakowv30011253m.g Saccoglossus kowalevskii Sakowv30011253m.g I 0.703