Sp4 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000025323 T101053_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within regulation of heart contraction. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in congenital heart disease and dilated cardiomyopathy. Orthologous to human SP4 (Sp4 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Sp4
M00133_2.00		 Mus musculus
HMCGCCCMYN
NRKGGGCGKD		 PBM
Badis et al.(2009)
Sp4_1011		 (Direct) (Direct)
Sp4
M01862_2.00		 Mus musculus
NMCGCCCMY
RKGGGCGKN		 PBM
Weirauch et al.(2014)
pTH4998		 (Direct) (Direct)
Sp4
M05859_2.00		 Mus musculus
DGNYMCGCCCHNN
NNDGGGCGKRNCH		 SMiLE-seq
Isakova et al.(2017)
SP4		 (Direct) (Direct)
Sp4
M08975_2.00		 Mus musculus
BYHDKCYCCGCCYYYHBSBB
VVSVDRRRGGCGGRGMHDRV		 Misc
Kulakovskiy et al.(2013)
SP4_MOUSE.H11MO.0.B		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SP4
M02879_2.00 		Homo sapiens
NWRGCCACGCCCMCHYN
NRDGKGGGCGTGGCYWN		 SELEX
Jolma et al.(2013)
SP4_1 		0.811 0.986
SP4
M08296_2.00 		Homo sapiens
NNVGCYCCKCCYMYH
DRKRGGMGGRGCBNN		 ChIP-seq
Schmitges et al.(2016)
Q02446.MEME 		0.811 0.986
SP4
M08873_2.00 		Homo sapiens
BYHDKCYCCGCCYYYHBSBB
VVSVDRRRGGCGGRGMHDRV		 Misc
Kulakovskiy et al.(2013)
SP4_HUMAN.H11MO.0.A 		0.811 0.986
SP4
M10165_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP4_Q3 		0.811 0.986
SP4
M10166_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP4_Q5 		0.811 0.986
Sp3
M08978_2.00 		Mus musculus
NBBNVSCCCCKCCCMBBBNN
NNVVVKGGGMGGGGSBNVVN		 Misc
Kulakovskiy et al.(2013)
SP3_MOUSE.H11MO.0.B 		0.782 0.942
Sp1
M00765_2.00 		Mus musculus
NMCGCCCMY
RKGGGCGKN		 PBM
Weirauch et al.(2013)
pTH0978 		0.775 0.899
Sp1
M08963_2.00 		Mus musculus
CCCBKCYCCKCCCCCNBCYCSBSC
GSVSGRGVNGGGGGMGGRGMVGGG		 Misc
Kulakovskiy et al.(2013)
SP1_MOUSE.H11MO.0.A 		0.775 0.899
Spps
M06159_2.00 		Drosophila melanogaster
KWDRCCMCGCCCMBH
DVKGGGCGKGGYHWM		 B1H
Zhu et al.(2011)
CG5669_SANGER_10_FBgn0039169 		0.772 0.870
Spps
M06160_2.00 		Drosophila melanogaster
BDDGCCMCGCCCMYN
NRKGGGCGKGGCHHV		 B1H
Zhu et al.(2011)
CG5669_SOLEXA_5_FBgn0039169 		0.772 0.870
SP1
M02921_2.00 		Homo sapiens
RCCMCDCCCMH
DKGGGHGKGGY		 SELEX
Jolma et al.(2013)
SP1_1 		0.772 0.884
SP1
M04605_2.00 		Homo sapiens
NWRRCCACGCCCMCH
DGKGGGCGTGGYYWN		 SELEX
Yin et al.(2017)
SP1_eDBD_HT-SELEX 		0.772 0.884
SP1
M08096_2.00 		Homo sapiens
BYCCCKCCCCY
RGGGGMGGGRV		 ChIP-seq
Mathelier et al.(2014)
MA0079.3 		0.772 0.884
SP1
M08363_2.00 		Homo sapiens
CCCHNBCYCCDCCCY
RGGGHGGRGVNDGGG		 ChIP-seq
Schmitges et al.(2016)
P08047.MEME 		0.772 0.884
SP1
M08938_2.00 		Homo sapiens
BCSSSBCCHVGCCCCGCCCCYN
NRGGGGCGGGGCBDGGVSSSGV		 Misc
Kulakovskiy et al.(2013)
SP1_HUMAN.H11MO.0.A 		0.772 0.884
SP1
M10294_2.00 		Homo sapiens
DSCMHGCCYH
DRGGCDKGSH		 Transfac
Matys et al.(2006)
V$SP1_01 		0.772 0.884
SP1
M10295_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP1_02 		0.772 0.884
SP1
M10296_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP1_07 		0.772 0.884
SP1
M10297_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP1_08 		0.772 0.884
SP1
M10298_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP1_Q2_02 		0.772 0.884
SP1
M10299_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP1_Q3 		0.772 0.884
SP1
M10300_2.00 		Homo sapiens
VVCCCCGCCCMBN
NVKGGGCGGGGBB		 Transfac
Matys et al.(2006)
V$SP1_Q6 		0.772 0.884
SP1
M04606_2.00 		Homo sapiens
NWRGCCMCGCCCMYH
DRKGGGCGKGGCYWN		 SELEX
Yin et al.(2017)
SP1_eDBD_Methyl-HT-SELEX 		0.772 0.884
Sp5
M09016_2.00 		Mus musculus
CYCCKCCYHYHBCYYHBYYYHYHB
VDRDRRRVDRRGVDRDRGGMGGRG		 Misc
Kulakovskiy et al.(2013)
SP5_MOUSE.H11MO.0.C 		0.769 0.899
SP5
M10319_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP5_Q2 		0.769 0.899
SP3
M02910_2.00 		Homo sapiens
VCCMCRCCCMY
RKGGGYGKGGB		 SELEX
Jolma et al.(2013)
SP3_1 		0.762 0.913
SP3
M04558_2.00 		Homo sapiens
NRCCACGCCCMYH
DRKGGGCGTGGYN		 SELEX
Yin et al.(2017)
SP3_eDBD_HT-SELEX 		0.762 0.913
SP3
M08920_2.00 		Homo sapiens
NBBNVSCCCCKCCCMBBBNN
NNVVVKGGGMGGGGSBNVVN		 Misc
Kulakovskiy et al.(2013)
SP3_HUMAN.H11MO.0.B 		0.762 0.913
SP3
M10263_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP3_Q3_01 		0.762 0.913
SP3
M10264_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SP3_Q3 		0.762 0.913
SP3
M04559_2.00 		Homo sapiens
NRCCMCGCCCMCH
DGKGGGCGKGGYN		 SELEX
Yin et al.(2017)
SP3_eDBD_Methyl-HT-SELEX 		0.762 0.913
SP8
M02898_2.00 		Homo sapiens
VMCACBCCCMCH
DGKGGGVGTGKB		 SELEX
Jolma et al.(2013)
SP8_1 		0.762 0.899
SP8
M04517_2.00 		Homo sapiens
NMCMCGCCCMYH
DRKGGGCGKGKN		 SELEX
Yin et al.(2017)
SP8_eDBD_HT-SELEX 		0.762 0.899
SP8
M04518_2.00 		Homo sapiens
RHCACGCCCMYH
DRKGGGCGTGDY		 SELEX
Yin et al.(2017)
SP8_eDBD_Methyl-HT-SELEX 		0.762 0.899
SP9
M04645_2.00 		Homo sapiens
VMCMCGCCCMYH
DRKGGGCGKGKB		 SELEX
Yin et al.(2017)
SP9_eDBD_HT-SELEX 		0.762 0.884
SP9
M04646_2.00 		Homo sapiens
RYCACGCCCMYH
DRKGGGCGTGRY		 SELEX
Yin et al.(2017)
SP9_eDBD_Methyl-HT-SELEX 		0.762 0.884
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00133_2.00 C2H2 ZF 16 40
M00133_2.00 C2H2 ZF 46 70
M00133_2.00 C2H2 ZF 76 98
M01862_2.00 C2H2 ZF 1 25
M01862_2.00 C2H2 ZF 31 55
M01862_2.00 C2H2 ZF 61 83

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000026367 C2H2 ZF 645 669
ENSMUSP00000026367 C2H2 ZF 675 699
ENSMUSP00000026367 C2H2 ZF 705 727

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

422 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Sp4 Rattus norvegicus ENSRNOG00000005472 I 0.827
SP4 Anolis carolinensis ENSACAG00000014193 I 0.811
SP4 Equus caballus ENSECAG00000023324 I 0.811
SP4 Otolemur garnettii ENSOGAG00000007284 I 0.811
ENSP00000222584 Macaca fascicularis ENSP00000222584 I 0.811
SP4 Tursiops truncatus ENSTTRG00000001927 I 0.811
ENSP00000222584-D1 Bos grunniens ENSP00000222584-D1 I 0.811
SP4 Gorilla gorilla ENSGGOG00000001332 I 0.811
ENSCSAG00000013609 Chlorocebus sabaeus ENSCSAG00000013609 I 0.811
SP4 Bos taurus ENSBTAG00000014389 I 0.811
ENSAMXG00000004713 Astyanax mexicanus ENSAMXG00000004713 I 0.811
ENSGALG00000010905 Gallus gallus ENSGALG00000010905 I 0.811
ENSOARG00000010410 Ovis aries ENSOARG00000010410 I 0.811
ENSNLEG00000016733 Nomascus leucogenys ENSNLEG00000016733 I 0.811
SP4 Callithrix jacchus ENSCJAG00000001282 I 0.811
SP4 Homo sapiens ENSG00000105866 D 0.811
ENSPPYG00000017746 Pongo abelii ENSPPYG00000017746 I 0.811
ENSPANG00000006251 Papio anubis ENSPANG00000006251 I 0.811
SP4 Macaca mulatta ENSMMUG00000021684 I 0.811
SP4 Cavia porcellus ENSCPOG00000015154 I 0.811
SP4 Pan troglodytes ENSPTRG00000018970 I 0.811
SP4 Meleagris gallopavo ENSMGAG00000010367 I 0.811
sp4 Danio rerio ENSDARG00000005186 I 0.811
XP_002166590.1 Hydra magnipapillata XP_002166590.1 I 0.804
HHAL002953-PA Halyomorpha halys HHAL002953-PA I 0.800
NV18748 Nasonia vitripennis NV18748 I 0.798
AARA006360 Anopheles arabiensis AARA006360 I 0.797
AQUA008497 Anopheles quadriannulatus AQUA008497 I 0.797
AGAP004438 Anopheles gambiae AGAP004438 I 0.797
AMEM016115 Anopheles merus AMEM016115 I 0.797
ENSFALG00000009748 Ficedula albicollis ENSFALG00000009748 I 0.795
sp4.L Xenopus laevis XB-GENE-983121 I 0.795
Pvit_02743 Pogona vitticeps Pvit_02743 I 0.795
sp4 Oryzias latipes ENSORLG00000003968 I 0.795
Afo_R003455 Aptenodytes forsteri Afo_R003455 I 0.795
SP4 Pteropus vampyrus ENSPVAG00000015251 I 0.795
SP4 Echinops telfairi ENSETEG00000018442 I 0.795
ENSTSYG00000005373 Tarsius syrichta ENSTSYG00000005373 I 0.795
Cmyd_10011498 Chelonia mydas Cmyd_10011498 I 0.795
ENSTGUG00000002680 Taeniopygia guttata ENSTGUG00000002680 I 0.795
ENSMEUG00000015091 Macropus eugenii ENSMEUG00000015091 I 0.795
ENSLOCG00000011495 Lepisosteus oculatus ENSLOCG00000011495 I 0.795
SP4 Myotis lucifugus ENSMLUG00000013137 I 0.795
SP4 Sorex araneus ENSSARG00000014308 I 0.795
ENSMPUG00000013911 Mustela putorius furo ENSMPUG00000013911 I 0.795
SP4 Monodelphis domestica ENSMODG00000001368 I 0.795
ENSSHAG00000015005 Sarcophilus harrisii ENSSHAG00000015005 I 0.795
ENSTGUG00000014104 Taeniopygia guttata ENSTGUG00000014104 I 0.795
SP4 Loxodonta africana ENSLAFG00000022398 I 0.795
SP4 Oryctolagus cuniculus ENSOCUG00000015345 I 0.795
sp4 Gasterosteus aculeatus ENSGACG00000006481 I 0.795
Alligator_sinensis_CCG001290.1 Alligator sinensis Alligator_sinensis_CCG001290.1 I 0.795
ENSXMAG00000000588 Xiphophorus maculatus ENSXMAG00000000588 I 0.795
Tal_R001648 Tyto alba Tal_R001648 I 0.795
ENSOANG00000029507 Ornithorhynchus anatinus ENSOANG00000029507 I 0.795
sp4 Tetraodon nigroviridis ENSTNIG00000002904 I 0.795
Brh_R009448 Buceros rhinoceros Brh_R009448 I 0.795
sp4 Takifugu rubripes ENSTRUG00000008217 I 0.795
ENSFCAG00000028758 Felis catus ENSFCAG00000028758 I 0.795
ENSONIG00000010872 Oreochromis niloticus ENSONIG00000010872 I 0.795
ENSAPLG00000010528 Anas platyrhynchos ENSAPLG00000010528 I 0.795
SP4 Canis familiaris ENSCAFG00000002671 I 0.795
Aqu1.217456 Amphimedon queenslandica Aqu1.217456 I 0.795
NEMVEDRAFT_v1g27142 Nematostella vectensis NEMVEDRAFT_v1g27142 I 0.795
ENSPFOG00000001626 Poecilia formosa ENSPFOG00000001626 I 0.795
ACEP10169 Atta cephalotes ACEP10169 I 0.795
Gfo_R015871 Geospiza fortis Gfo_R015871 I 0.795
Aan_R001055 Calypte anna Aan_R001055 I 0.795
Myotis_brandtii_SP4_10031725 Myotis brandtii Myotis_brandtii_SP4_10031725 I 0.795
ENSPSIG00000009131 Pelodiscus sinensis ENSPSIG00000009131 I 0.795
Ogr11542 Ophisaurus gracilis Ogr11542 I 0.795
ASTEI04919 Anopheles stephensi ASTEI04919 I 0.794
AMAM018005 Anopheles maculatus AMAM018005 I 0.794
ACUA022057 Anopheles culicifacies ACUA022057 I 0.794
AFUN009419 Anopheles funestus AFUN009419 I 0.794
ACHR002282 Anopheles christyi ACHR002282 I 0.794
Ocbimv22017043m.g Octopus bimaculoides Ocbimv22017043m.g I 0.792
sp4 Xenopus tropicalis XB-GENE-983118 I 0.791
LotgiG126809 Lottia gigantea LotgiG126809 I 0.791
L798_03976 Zootermopsis nevadensis L798_03976 I 0.788
Gfo_R005030 Geospiza fortis Gfo_R005030 I 0.788
ENSGALG00000028401 Gallus gallus ENSGALG00000028401 I 0.788
ENSAPLG00000007170 Anas platyrhynchos ENSAPLG00000007170 I 0.788
TriadG7637 Trichoplax adhaerens TriadG7637 I 0.788
ENSGMOG00000001311 Gadus morhua ENSGMOG00000001311 I 0.788
ISCW020450 Ixodes scapularis ISCW020450 I 0.788
SP1 Taeniopygia guttata ENSTGUG00000015642 I 0.788
sp5l Takifugu rubripes ENSTRUG00000012835 I 0.787
KGM_00588 Danaus plexippus KGM_00588 I 0.785
CLEC006997 Cimex lectularius CLEC006997 I 0.785
PHUM363930 Pediculus humanus PHUM363930 I 0.784
CGI_10013026 Crassostrea gigas CGI_10013026 I 0.782
SP3 Cavia porcellus ENSCPOG00000002942 I 0.782
SP3 Pteropus vampyrus ENSPVAG00000000981 I 0.782
ENSBTAP00000000201-D1 Bos grunniens ENSBTAP00000000201-D1 I 0.782
ENSOARG00000000469 Ovis aries ENSOARG00000000469 I 0.782
SP3 Anolis carolinensis ENSACAG00000017061 I 0.782
Sp3 Rattus norvegicus ENSRNOG00000060479 I 0.782
SP3 Dasypus novemcinctus ENSDNOG00000048996 I 0.782
SP3 Erinaceus europaeus ENSEEUG00000005069 I 0.782
Sp3 Dipodomys ordii ENSDORG00000009045 I 0.782
SP3 Tursiops truncatus ENSTTRG00000016998 I 0.782
SP3 Bos taurus ENSBTAG00000000176 I 0.782
ENSSSCG00000026327 Sus scrofa ENSSSCG00000026327 I 0.782
ENSSTOG00000023955 Ictidomys tridecemlineatus ENSSTOG00000023955 I 0.782
Sp3 Mus musculus ENSMUSG00000027109 D 0.782
SP3 Sus scrofa ENSSSCG00000015962 I 0.782
SP3 Otolemur garnettii ENSOGAG00000026846 I 0.782
ASIS011603 Anopheles sinensis ASIS011603 I 0.781
AATE004178 Anopheles atroparvus AATE004178 I 0.781
ENSPMAG00000001574 Petromyzon marinus ENSPMAG00000001574 I 0.781
Alligator_sinensis_CCG010641.1 Alligator sinensis Alligator_sinensis_CCG010641.1 I 0.779
GB41800 Apis mellifera GB41800 I 0.779
ENSAMXG00000024690 Astyanax mexicanus ENSAMXG00000024690 I 0.779
Ocbimv22028510m.g Octopus bimaculoides Ocbimv22028510m.g I 0.778
ENSAMXG00000015260 Astyanax mexicanus ENSAMXG00000015260 I 0.778
AALB008691 Anopheles albimanus AALB008691 I 0.778
AFAF018385 Anopheles farauti AFAF018385 I 0.778
ADAC004751 Anopheles darlingi ADAC004751 I 0.778
SP3 Microcebus murinus ENSMICG00000014796 I 0.778
LLOJ008095 Lutzomyia longipalpis LLOJ008095 I 0.778
Sakowv30026929m.g Saccoglossus kowalevskii Sakowv30026929m.g I 0.776
tetur08g03750 Tetranychus urticae tetur08g03750 I 0.776
MDOA015575 Musca domestica MDOA015575 I 0.776
sp1.L Xenopus laevis XB-GENE-6251554 I 0.776
sp1 Oryzias latipes ENSORLG00000005195 I 0.776
ENSOARG00000016514 Ovis aries ENSOARG00000016514 I 0.776
sp1 Tetraodon nigroviridis ENSTNIG00000007066 I 0.776
ENSBTAP00000003929-D1 Bos grunniens ENSBTAP00000003929-D1 I 0.776
SP1 Bos taurus ENSBTAG00000003021 I 0.776
Pvit_07435 Pogona vitticeps Pvit_07435 I 0.776
ENSPSIG00000007013 Pelodiscus sinensis ENSPSIG00000007013 I 0.776
ENSLACG00000011942 Latimeria chalumnae ENSLACG00000011942 I 0.776
Ogr16979 Ophisaurus gracilis Ogr16979 I 0.776
sp1 Takifugu rubripes ENSTRUG00000014305 I 0.776
Cmyd_10006878 Chelonia mydas Cmyd_10006878 I 0.776
sp3b Danio rerio ENSDARG00000007812 I 0.775
sp3a Danio rerio ENSDARG00000001549 I 0.775
Sp1 Mus musculus ENSMUSG00000001280 D 0.775
sp5l.S Xenopus laevis XB-GENE-6485591 I 0.775
sp5l Xenopus tropicalis XB-GENE-1000647 I 0.775
ENSLACG00000018513 Latimeria chalumnae ENSLACG00000018513 I 0.775
ENSAMXG00000004915 Astyanax mexicanus ENSAMXG00000004915 I 0.775
e_gw.339.61.1 Branchiostoma floridae e_gw.339.61.1 I 0.775
estExt_fgenesh2_pg.C_1820063 Branchiostoma floridae estExt_fgenesh2_pg.C_1820063 I 0.775
Sp1 Rattus norvegicus ENSRNOG00000014084 I 0.775
ENSPPYG00000004579 Pongo abelii ENSPPYG00000004579 I 0.772
ENSPFOG00000007682 Poecilia formosa ENSPFOG00000007682 I 0.772
SP1 Pan troglodytes ENSPTRG00000005014 I 0.772
ENSPANG00000018241 Papio anubis ENSPANG00000018241 I 0.772
SP1 Pteropus vampyrus ENSPVAG00000012280 I 0.772
SP1 Ochotona princeps ENSOPRG00000000691 I 0.772
SP1 Procavia capensis ENSPCAG00000004934 I 0.772
Myotis_brandtii_SP1_10022992 Myotis brandtii Myotis_brandtii_SP1_10022992 I 0.772
ENSNLEG00000017699 Nomascus leucogenys ENSNLEG00000017699 I 0.772
SP1 Oryctolagus cuniculus ENSOCUG00000004147 I 0.772
ENSMMUP00000026353 Macaca fascicularis ENSMMUP00000026353 I 0.772
SP1 Sorex araneus ENSSARG00000013480 I 0.772
Alligator_sinensis_CCG005388.1 Alligator sinensis Alligator_sinensis_CCG005388.1 I 0.772
SP1 Cavia porcellus ENSCPOG00000023095 I 0.772
ENSCSAG00000005498 Chlorocebus sabaeus ENSCSAG00000005498 I 0.772
GD18309 Drosophila simulans FBgn0085065 I 0.772
SP1 Callithrix jacchus ENSCJAG00000018553 I 0.772
GF18887 Drosophila ananassae FBgn0095901 I 0.772
GG12363 Drosophila erecta FBgn0084750 I 0.772
sp1 Danio rerio ENSDARG00000088347 I 0.772
Spps Drosophila melanogaster FBgn0039169 D 0.772
SP1 Sus scrofa ENSSSCG00000000272 I 0.772
SP1 Dasypus novemcinctus ENSDNOG00000017346 I 0.772
GE10816 Drosophila yakuba FBgn0084743 I 0.772
SP1 Choloepus hoffmanni ENSCHOG00000001703 I 0.772
GH18919 Drosophila grimshawi FBgn0126386 I 0.772
SP1 Anolis carolinensis ENSACAG00000000610 I 0.772
GK11712 Drosophila willistoni FBgn0213723 I 0.772
Aan_R009568 Calypte anna Aan_R009568 I 0.772
DAPPUDRAFT_315784 Daphnia pulex DAPPUDRAFT_315784 I 0.772
TC012895 Tribolium castaneum TC012895 I 0.772
ENSAMEG00000012479 Ailuropoda melanoleuca ENSAMEG00000012479 I 0.772
GJ14523 Drosophila virilis FBgn0201734 I 0.772
GI23419 Drosophila mojavensis FBgn0146145 I 0.772
SP1 Canis familiaris ENSCAFG00000006950 I 0.772
GL24133 Drosophila persimilis FBgn0161723 I 0.772
GM23502 Drosophila sechellia FBgn0178369 I 0.772
ENSXMAG00000017829 Xiphophorus maculatus ENSXMAG00000017829 I 0.772
GA19045 Drosophila pseudoobscura FBgn0079043 I 0.772
ENSTSYG00000001068 Tarsius syrichta ENSTSYG00000001068 I 0.772
ENSGACG00000006667 Gasterosteus aculeatus ENSGACG00000006667 I 0.772
LDEC007243 Leptinotarsa decemlineata LDEC007243 I 0.772
SP1 Macaca mulatta ENSMMUG00000020036 I 0.772
SP1 Tupaia belangeri ENSTBEG00000010202 I 0.772
SP1 Loxodonta africana ENSLAFG00000018043 I 0.772
ENSMEUG00000004493 Macropus eugenii ENSMEUG00000004493 I 0.772
SP1 Gorilla gorilla ENSGGOG00000012593 I 0.772
ENSSTOG00000005928 Ictidomys tridecemlineatus ENSSTOG00000005928 I 0.772
SP1 Myotis lucifugus ENSMLUG00000017303 I 0.772
SP1 Tursiops truncatus ENSTTRG00000009591 I 0.772
SP1 Erinaceus europaeus ENSEEUG00000013568 I 0.772
ENSECAG00000020197 Equus caballus ENSECAG00000020197 I 0.772
SP1 Homo sapiens ENSG00000185591 D 0.772
SP1 Felis catus ENSFCAG00000030741 I 0.772
ENSONIG00000012117 Oreochromis niloticus ENSONIG00000012117 I 0.771
sp5l Oryzias latipes ENSORLG00000007526 I 0.771
ENSPFOG00000001566 Poecilia formosa ENSPFOG00000001566 I 0.771
ENSGMOG00000004393 Gadus morhua ENSGMOG00000004393 I 0.771
ENSPFOG00000008204 Poecilia formosa ENSPFOG00000008204 I 0.771
sp5l Danio rerio ENSDARG00000010124 I 0.771
ENSXMAG00000010161 Xiphophorus maculatus ENSXMAG00000010161 I 0.771
sp5l Gasterosteus aculeatus ENSGACG00000008991 I 0.771
ENSSTOG00000008099 Ictidomys tridecemlineatus ENSSTOG00000008099 I 0.769
SMAR004952 Strigamia maritima SMAR004952 I 0.769
ENSP00000364430 Macaca fascicularis ENSP00000364430 I 0.769
ENSPPYG00000012923 Pongo abelii ENSPPYG00000012923 I 0.769
ENSBTAP00000004166-D1 Bos grunniens ENSBTAP00000004166-D1 I 0.769
SP5 Tursiops truncatus ENSTTRG00000004531 I 0.769
SP5 Pan troglodytes ENSPTRG00000029149 I 0.769
SP5 Pteropus vampyrus ENSPVAG00000006625 I 0.769
Alligator_sinensis_CCG008293.1 Alligator sinensis Alligator_sinensis_CCG008293.1 I 0.769
Sp5 Rattus norvegicus ENSRNOG00000054086 I 0.769
Sp5 Mus musculus ENSMUSG00000075304 D 0.769
SP5 Loxodonta africana ENSLAFG00000002720 I 0.769
ENSGGOG00000027746 Gorilla gorilla ENSGGOG00000027746 I 0.769
ENSGALG00000027511 Gallus gallus ENSGALG00000027511 I 0.769
LCUP000151 Lucilia cuprina LCUP000151 I 0.769
SP5 Myotis lucifugus ENSMLUG00000028807 I 0.769
ENSMPUG00000000796 Mustela putorius furo ENSMPUG00000000796 I 0.769
SP5 Monodelphis domestica ENSMODG00000008446 I 0.769
SP5 Macaca mulatta ENSMMUG00000002690 I 0.769
sp5.L Xenopus laevis XB-GENE-6254266 I 0.769
SP5 Homo sapiens ENSG00000204335 D 0.769
SP5 Canis familiaris ENSCAFG00000012550 I 0.769
SP5 Bos taurus ENSBTAG00000003207 I 0.769
ENSAMEG00000010417 Ailuropoda melanoleuca ENSAMEG00000010417 I 0.769
SP5 Callithrix jacchus ENSCJAG00000006965 I 0.769
ENSCPOG00000011747 Cavia porcellus ENSCPOG00000011747 I 0.769
SP5 Felis catus ENSFCAG00000012078 I 0.769
ENSDORG00000012608 Dipodomys ordii ENSDORG00000012608 I 0.769
ENSCSAG00000015012 Chlorocebus sabaeus ENSCSAG00000015012 I 0.769
ENSNLEG00000005184 Nomascus leucogenys ENSNLEG00000005184 I 0.769
sp5 Xenopus tropicalis XB-GENE-1217606 I 0.769
SP5 Procavia capensis ENSPCAG00000017098 I 0.769
Myotis_brandtii_Sp5_10034946 Myotis brandtii Myotis_brandtii_Sp5_10034946 I 0.769
ENSPANG00000015015 Papio anubis ENSPANG00000015015 I 0.769
ENSXMAG00000000590 Xiphophorus maculatus ENSXMAG00000000590 I 0.768
ENSONIG00000010871 Oreochromis niloticus ENSONIG00000010871 I 0.768
sp5.S Xenopus laevis XB-GENE-1217613 I 0.768
ENSPMAG00000008063 Petromyzon marinus ENSPMAG00000008063 I 0.768
ENSONIG00000005121 Oreochromis niloticus ENSONIG00000005121 I 0.768
SP8 Takifugu rubripes ENSTRUG00000008153 I 0.768
SP8 Tetraodon nigroviridis ENSTNIG00000002903 I 0.768
ACYPI008586 Acyrthosiphon pisum ACYPI008586 I 0.768
ENSSHAG00000013923 Sarcophilus harrisii ENSSHAG00000013923 I 0.766
Myotis_brandtii_Sp3_10034975 Myotis brandtii Myotis_brandtii_Sp3_10034975 I 0.766
Gfo_R001364 Geospiza fortis Gfo_R001364 I 0.766
ENSFALG00000002922 Ficedula albicollis ENSFALG00000002922 I 0.766
SP3 Procavia capensis ENSPCAG00000002179 I 0.766
SP3 Monodelphis domestica ENSMODG00000009184 I 0.766
SP3 Ochotona princeps ENSOPRG00000005517 I 0.766
SP3 Oryctolagus cuniculus ENSOCUG00000026678 I 0.766
SP3 Sorex araneus ENSSARG00000011358 I 0.766
SP3 Felis catus ENSFCAG00000030033 I 0.766
ENSTSYG00000008651 Tarsius syrichta ENSTSYG00000008651 I 0.766
ENSAMEG00000000258 Ailuropoda melanoleuca ENSAMEG00000000258 I 0.766
SP5 Anolis carolinensis ENSACAG00000016843 I 0.766
ENSGALG00000009327 Gallus gallus ENSGALG00000009327 I 0.766
SP3 Canis familiaris ENSCAFG00000013169 I 0.766
Brh_R011836 Buceros rhinoceros Brh_R011836 I 0.766
SP3 Taeniopygia guttata ENSTGUG00000008690 I 0.766
SP3 Meleagris gallopavo ENSMGAG00000009845 I 0.766
SP3 Myotis lucifugus ENSMLUG00000006791 I 0.766
SPU_024189 Strongylocentrotus purpuratus SPU_024189 I 0.766
NEMVEDRAFT_v1g28237 Nematostella vectensis NEMVEDRAFT_v1g28237 I 0.766
SP3 Tupaia belangeri ENSTBEG00000011156 I 0.766
SP3 Loxodonta africana ENSLAFG00000013121 I 0.766
ENSMPUG00000013903 Mustela putorius furo ENSMPUG00000013903 I 0.766
AAEL003875 Aedes aegypti AAEL003875 I 0.765
CapteG112714 Capitella teleta CapteG112714 I 0.765
ENSAMXG00000011277 Astyanax mexicanus ENSAMXG00000011277 I 0.765
TMUE_s0106000200 Trichuris muris TMUE_s0106000200 I 0.765
SP5 Ornithorhynchus anatinus ENSOANG00000008556 I 0.765
TTRE_0000693001 Trichuris trichiura TTRE_0000693001 I 0.765
CPIJ003609 Culex quinquefasciatus CPIJ003609 I 0.765
D918_01017 Trichuris suis D918_01017 I 0.765
CpipJ_CPIJ003609 Culex pipiens CpipJ_CPIJ003609 I 0.765
GB48277 Apis mellifera GB48277 I 0.765
RSKR_0000732400 Rhabditophanes kr3021 RSKR_0000732400 I 0.764
ENSPSIG00000017208 Pelodiscus sinensis ENSPSIG00000017208 I 0.763
ENSPFOG00000013312 Poecilia formosa ENSPFOG00000013312 I 0.763
D917_04158 Trichinella nativa D917_04158 I 0.763
Aan_R000276 Calypte anna Aan_R000276 I 0.763
SMAR004861 Strigamia maritima SMAR004861 I 0.763
LotgiG58417 Lottia gigantea LotgiG58417 I 0.763
CGI_10007690 Crassostrea gigas CGI_10007690 I 0.763
EFV52203 Trichinella spiralis EFV52203 I 0.763
BXY_0564300 Bursaphelenchus xylophilus BXY_0564300 I 0.763
ENSAPLG00000008201 Anas platyrhynchos ENSAPLG00000008201 I 0.763
sp3a Gasterosteus aculeatus ENSGACG00000004770 I 0.763
sp3b Tetraodon nigroviridis ENSTNIG00000017208 I 0.763
ENSONIG00000001262 Oreochromis niloticus ENSONIG00000001262 I 0.763
ENSGMOG00000000587 Gadus morhua ENSGMOG00000000587 I 0.763
sp3b Takifugu rubripes ENSTRUG00000015246 I 0.763
Cflo_10237--XP_624316.2_APIME Camponotus floridanus Cflo_10237--XP_624316.2_APIME I 0.763
ENSLACG00000010415 Latimeria chalumnae ENSLACG00000010415 I 0.763
Pvit_02955 Pogona vitticeps Pvit_02955 I 0.763
ENSONIG00000008666 Oreochromis niloticus ENSONIG00000008666 I 0.763
ENSLOCG00000007414 Lepisosteus oculatus ENSLOCG00000007414 I 0.763
Ocbimv22023102m.g Octopus bimaculoides Ocbimv22023102m.g I 0.763
sp3a Oryzias latipes ENSORLG00000017474 I 0.763
Sakowv30026949m.g Saccoglossus kowalevskii Sakowv30026949m.g I 0.763
Afo_R006914 Aptenodytes forsteri Afo_R006914 I 0.763
Tal_R005247 Tyto alba Tal_R005247 I 0.763
sp3.S Xenopus laevis XB-GENE-977162 I 0.763
ENSXMAG00000005322 Xiphophorus maculatus ENSXMAG00000005322 I 0.763
sp3b Gasterosteus aculeatus ENSGACG00000010072 I 0.763
sp3 Xenopus tropicalis XB-GENE-977158 I 0.763
SP3 Ornithorhynchus anatinus ENSOANG00000008599 I 0.763
TC011696 Tribolium castaneum TC011696 I 0.762
Pvit_11839 Pogona vitticeps Pvit_11839 I 0.762
Sakowv30026942m.g Saccoglossus kowalevskii Sakowv30026942m.g I 0.762
sp8.L Xenopus laevis XB-GENE-1216193 I 0.762
ENSP00000310301 Macaca fascicularis ENSP00000310301 I 0.762
XP_002933332 Xenopus tropicalis XP_002933332 I 0.762
XP_002933331 Xenopus tropicalis XP_002933331 I 0.762
sp9 Xenopus tropicalis XB-GENE-5931012 I 0.762
XP_002933333 Xenopus tropicalis XP_002933333 I 0.762
Cmyd_10010806 Chelonia mydas Cmyd_10010806 I 0.762
ENSPFOG00000007998 Poecilia formosa ENSPFOG00000007998 I 0.762
SP9 Gorilla gorilla ENSGGOG00000007345 I 0.762
ENSGGOG00000011699 Gorilla gorilla ENSGGOG00000011699 I 0.762
ENSGMOG00000004590 Gadus morhua ENSGMOG00000004590 I 0.762
ENSGMOG00000008078 Gadus morhua ENSGMOG00000008078 I 0.762
sp8b Gasterosteus aculeatus ENSGACG00000008062 I 0.762
SP9 Gasterosteus aculeatus ENSGACG00000004757 I 0.762
SP8 Erinaceus europaeus ENSEEUG00000000621 I 0.762
SP8 Homo sapiens ENSG00000164651 D 0.762
SP3 Homo sapiens ENSG00000172845 D 0.762
SP9 Homo sapiens ENSG00000217236 D 0.762
ENSLACG00000005288 Latimeria chalumnae ENSLACG00000005288 I 0.762
ENSLOCG00000007391 Lepisosteus oculatus ENSLOCG00000007391 I 0.762
SP9 Macaca mulatta ENSMMUG00000023005 I 0.762
SP8 Monodelphis domestica ENSMODG00000001375 I 0.762
SPU_016114 Strongylocentrotus purpuratus SPU_016114 I 0.762
ENSMPUG00000013919 Mustela putorius furo ENSMPUG00000013919 I 0.762
SP3 Macaca mulatta ENSMMUG00000021818 I 0.762
SP8 Macaca mulatta ENSMMUG00000003722 I 0.762
ENSLOCG00000007577 Lepisosteus oculatus ENSLOCG00000007577 I 0.762
ENSLOCG00000011486 Lepisosteus oculatus ENSLOCG00000011486 I 0.762
ENSMEUG00000012808 Macropus eugenii ENSMEUG00000012808 I 0.762
SP3 Equus caballus ENSECAG00000013930 I 0.762
SP9 Dasypus novemcinctus ENSDNOG00000019150 I 0.762
ENSAMXG00000004709 Astyanax mexicanus ENSAMXG00000004709 I 0.762
ENSAMXG00000015246 Astyanax mexicanus ENSAMXG00000015246 I 0.762
ENSAMXG00000020011 Astyanax mexicanus ENSAMXG00000020011 I 0.762
SP8 Bos taurus ENSBTAG00000002604 I 0.762
DAPPUDRAFT_106303 Daphnia pulex DAPPUDRAFT_106303 I 0.762
CGI_10004780 Crassostrea gigas CGI_10004780 I 0.762
BGIBMGA006942 Bombyx mori BGIBMGA006942 I 0.762
CapteG224157 Capitella teleta CapteG224157 I 0.762
CapteG39158 Capitella teleta CapteG39158 I 0.762
SP9 Bos taurus ENSBTAG00000014949 I 0.762
SP8 Callithrix jacchus ENSCJAG00000001245 I 0.762
FO704755.1 Danio rerio ENSDARG00000005846 I 0.762
sp8a Danio rerio ENSDARG00000011870 I 0.762
sp8b Danio rerio ENSDARG00000056666 I 0.762
sp9 Danio rerio ENSDARG00000099374 I 0.762
ENSCSAG00000014689 Chlorocebus sabaeus ENSCSAG00000014689 I 0.762
ENSCSAG00000014648 Chlorocebus sabaeus ENSCSAG00000014648 I 0.762
SP3 Callithrix jacchus ENSCJAG00000007851 I 0.762
SP8 Cavia porcellus ENSCPOG00000026910 I 0.762
ENSCSAG00000013600 Chlorocebus sabaeus ENSCSAG00000013600 I 0.762
Sp8 Mus musculus ENSMUSG00000048562 I 0.762
SP9 Monodelphis domestica ENSMODG00000009303 I 0.762
ENSTGUG00000002679 Taeniopygia guttata ENSTGUG00000002679 I 0.762
SP9 Tetraodon nigroviridis ENSTNIG00000016949 I 0.762
sp8b Tetraodon nigroviridis ENSTNIG00000018442 I 0.762
Sp9 Mus musculus ENSMUSG00000068859 I 0.762
ENSSSCG00000029407 Sus scrofa ENSSSCG00000029407 I 0.762
SP8 Pteropus vampyrus ENSPVAG00000005109 I 0.762
Sp8 Rattus norvegicus ENSRNOG00000005943 I 0.762
Sp9 Rattus norvegicus ENSRNOG00000028187 I 0.762
sp8b Takifugu rubripes ENSTRUG00000015810 I 0.762
SP9 Takifugu rubripes ENSTRUG00000017609 I 0.762
NEMVEDRAFT_v1g99612 Nematostella vectensis NEMVEDRAFT_v1g99612 I 0.762
SMAR004954 Strigamia maritima SMAR004954 I 0.762
SPU_011280 Strongylocentrotus purpuratus SPU_011280 I 0.762
MCINX013793 Melitaea cinxia MCINX013793 I 0.762
KGM_00011 Danaus plexippus KGM_00011 I 0.762
SP8 Tursiops truncatus ENSTTRG00000013387 I 0.762
ENSXMAG00000005380 Xiphophorus maculatus ENSXMAG00000005380 I 0.762
ISCW023685 Ixodes scapularis ISCW023685 I 0.762
SP8 Pan troglodytes ENSPTRG00000018968 I 0.762
ENSSTOG00000028058 Ictidomys tridecemlineatus ENSSTOG00000028058 I 0.762
ENSPANG00000016221 Papio anubis ENSPANG00000016221 I 0.762
ENSPANG00000023061 Papio anubis ENSPANG00000023061 I 0.762
ENSPANG00000005418 Papio anubis ENSPANG00000005418 I 0.762
SP9 Oryzias latipes ENSORLG00000017492 I 0.762
SP3 Pan troglodytes ENSPTRG00000012647 I 0.762
ENSONIG00000002896 Oreochromis niloticus ENSONIG00000002896 I 0.762
SP9 Otolemur garnettii ENSOGAG00000034062 I 0.762
ENSONIG00000008657 Oreochromis niloticus ENSONIG00000008657 I 0.762
ENSPPYG00000012941 Pongo abelii ENSPPYG00000012941 I 0.762
ENSPPYG00000017747 Pongo abelii ENSPPYG00000017747 I 0.762
ENSNLEG00000016729 Nomascus leucogenys ENSNLEG00000016729 I 0.762
ENSPFOG00000013459 Poecilia formosa ENSPFOG00000013459 I 0.762
SP9 Procavia capensis ENSPCAG00000012721 I 0.762
sp8b Oryzias latipes ENSORLG00000007242 I 0.762
BGLB013141 Biomphalaria glabrata BGLB013141 I 0.761
SBAD_0000755901 Soboliphyme baturini SBAD_0000755901 I 0.761
Ocbimv22028516m.g Octopus bimaculoides Ocbimv22028516m.g I 0.759
tetur22g00570 Tetranychus urticae tetur22g00570 I 0.759
DAPPUDRAFT_114437 Daphnia pulex DAPPUDRAFT_114437 I 0.759
sp3b Oryzias latipes ENSORLG00000013706 I 0.759
sp3a Takifugu rubripes ENSTRUG00000017623 I 0.759
ENSXMAG00000009872 Xiphophorus maculatus ENSXMAG00000009872 I 0.759
ENSPFOG00000016261 Poecilia formosa ENSPFOG00000016261 I 0.759
sp3a Tetraodon nigroviridis ENSTNIG00000016947 I 0.759
sp5l Tetraodon nigroviridis ENSTNIG00000015074 I 0.758
Aan_R004593 Calypte anna Aan_R004593 I 0.756
ENSOARG00000002449 Ovis aries ENSOARG00000002449 I 0.756
CapteG39149 Capitella teleta CapteG39149 I 0.756
SP5 Taeniopygia guttata ENSTGUG00000008736 I 0.756
BGLB011938 Biomphalaria glabrata BGLB011938 I 0.756
ENSECAG00000002849 Equus caballus ENSECAG00000002849 I 0.755