HHAL006775-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL006775-PA T144079_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
wor
M03664_2.00 		Drosophila melanogaster
GYRACAGGTGYAH
DTRCACCTGTYRC		 SELEX
Nitta et al.(2015)
wor_1 		0.781 0.867
wor
M03665_2.00 		Drosophila melanogaster
DTRCACCTGTYGY
RCRACAGGTGYAH		 SELEX
Nitta et al.(2015)
wor_2 		0.781 0.867
wor
M06051_2.00 		Drosophila melanogaster
CACCTGY
RCAGGTG		 B1H
Zhu et al.(2011)
wor_SANGER_2.5_FBgn0001983 		0.781 0.867
wor
M06052_2.00 		Drosophila melanogaster
VCACCTGY
RCAGGTGB		 B1H
Zhu et al.(2011)
wor_SOLEXA_2.5_FBgn0001983 		0.781 0.867
esg
M06050_2.00 		Drosophila melanogaster
CACCTGH
DCAGGTG		 B1H
Zhu et al.(2011)
esg_SANGER_2.5_FBgn0001981 		0.781 0.876
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL006775-PA C2H2 ZF 199 221
HHAL006775-PA C2H2 ZF 234 256
HHAL006775-PA C2H2 ZF 260 282
HHAL006775-PA C2H2 ZF 288 310
HHAL006775-PA C2H2 ZF 316 336

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

47 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CLEC007039 Cimex lectularius CLEC007039 I 0.823
RPRC005707 Rhodnius prolixus RPRC005707 I 0.815
PHUM091060 Pediculus humanus PHUM091060 I 0.804
L798_10614 Zootermopsis nevadensis L798_10614 I 0.803
PPAI008011 Phlebotomus papatasi PPAI008011 I 0.790
TC014474 Tribolium castaneum TC014474 I 0.786
NV17743 Nasonia vitripennis NV17743 I 0.786
Cflo_07707--XP_393944.1_APIME Camponotus floridanus Cflo_07707--XP_393944.1_APIME I 0.784
LDEC001157 Leptinotarsa decemlineata LDEC001157 I 0.784
BGIBMGA006230 Bombyx mori BGIBMGA006230 I 0.783
HMEL002306 Heliconius melpomene HMEL002306 I 0.783
KGM_17970 Danaus plexippus KGM_17970 I 0.783
MCINX001355 Melitaea cinxia MCINX001355 I 0.783
GD24004 Drosophila simulans FBgn0195364 I 0.781
GK18253 Drosophila willistoni FBgn0220252 I 0.781
GD21956 Drosophila simulans FBgn0193371 I 0.781
GE20968 Drosophila yakuba FBgn0238253 I 0.781
GE19402 Drosophila yakuba FBgn0236745 I 0.781
GL26594 Drosophila persimilis FBgn0164176 I 0.781
GF15382 Drosophila ananassae FBgn0092407 I 0.781
GG24207 Drosophila erecta FBgn0116339 I 0.781
GF14525 Drosophila ananassae FBgn0091552 I 0.781
GA17994 Drosophila pseudoobscura FBgn0078003 I 0.781
esg Drosophila melanogaster FBgn0001981 D 0.781
wor Drosophila melanogaster FBgn0001983 D 0.781
GM14357 Drosophila sechellia FBgn0169282 I 0.781
GG25158 Drosophila erecta FBgn0117283 I 0.781
ACEP13085 Atta cephalotes ACEP13085 I 0.780
SINV14155 Solenopsis invicta SINV14155 I 0.780
estExt_fgenesh2_kg.C_190001 Branchiostoma floridae estExt_fgenesh2_kg.C_190001 I 0.780
SMAR001730 Strigamia maritima SMAR001730 I 0.779
GJ23203 Drosophila virilis FBgn0210305 I 0.779
GH13119 Drosophila grimshawi FBgn0120596 I 0.779
GI22651 Drosophila mojavensis FBgn0145379 I 0.779
LCUP013268 Lucilia cuprina LCUP013268 I 0.778
MDOA014024 Musca domestica MDOA014024 I 0.778
GK18133 Drosophila willistoni FBgn0220132 I 0.778
GH13754 Drosophila grimshawi FBgn0121230 I 0.778
GL26425 Drosophila persimilis FBgn0164007 I 0.778
GJ17399 Drosophila virilis FBgn0204571 I 0.778
GA17666 Drosophila pseudoobscura FBgn0077676 I 0.778
GI17894 Drosophila mojavensis FBgn0140635 I 0.778
SMAR001314 Strigamia maritima SMAR001314 I 0.777
LotgiG114290 Lottia gigantea LotgiG114290 I 0.773
CapteG76255 Capitella teleta CapteG76255 I 0.769
CGI_10027813 Crassostrea gigas CGI_10027813 I 0.767
Sakowv30043351m.g Saccoglossus kowalevskii Sakowv30043351m.g I 0.766