ENSP00000322568 (Macaca fascicularis)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00505 (HMG_box) IPR000910 ENSP00000322568 T333711_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Sox11
M00210_2.00 		Mus musculus
WTTGTBNNN
NNNVACAAW		 PBM
Badis et al.(2009)
Sox11_2266 		0.505 0.983
Sox11
M03541_2.00 		Mus musculus
AACAATTKCAGTGTT
AACACTGMAATTGTT		 SELEX
Jolma et al.(2013)
Sox11_1 		0.505 0.983
SOX11
M11326_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SOX11_Q6 		0.505 0.983
SOX4
M01026_2.00 		Homo sapiens
AACAAWGR
YCWTTGTT		 PBM
Scharer et al.(2009)
Sox4 		0.505 0.931
SOX4
M03496_2.00 		Homo sapiens
NAACAATTKCAGTGTT
AACACTGMAATTGTTN		 SELEX
Jolma et al.(2013)
SOX4_1 		0.505 0.931
SOX4
M05765_2.00 		Homo sapiens
NRACAAWGVV
BBCWTTGTYN		 SELEX
Yin et al.(2017)
SOX4_eDBD_HT-SELEX 		0.505 0.931
SOX4
M09388_2.00 		Homo sapiens
BYCTTTGTYYBB
VVRRACAAAGRV		 Misc
Kulakovskiy et al.(2013)
SOX4_HUMAN.H11MO.0.B 		0.505 0.931
SOX4
M11301_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SOX4_Q3 		0.505 0.931
SOX4
M11302_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SOX4_Q5_02 		0.505 0.931
SOX4
M11303_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SOX4_Q5 		0.505 0.931
SOX4
M05766_2.00 		Homo sapiens
NRACAAWGVV
BBCWTTGTYN		 SELEX
Yin et al.(2017)
SOX4_eDBD_Methyl-HT-SELEX 		0.505 0.931
Sox4
M00213_2.00 		Mus musculus
NNVACAAWD
HWTTGTBNN		 PBM
Badis et al.(2009)
Sox4_2941 		0.505 0.914
Sox4
M09410_2.00 		Mus musculus
BYCTTTGTYYBB
VVRRACAAAGRV		 Misc
Kulakovskiy et al.(2013)
SOX4_MOUSE.H11MO.0.A 		0.505 0.914
Sox4
M09641_2.00 		Mus musculus
BCWTTGTYCN
NGRACAAWGV		 Misc
Heinz et al.(2010)
proB-Sox4_GSE50066 		0.505 0.914
Sox12
M00205_2.00 		Mus musculus
HWTTGTBNNN
NNNVACAAWD		 PBM
Badis et al.(2009)
Sox12_3957 		0.435 0.828
SOX12
M05789_2.00 		Homo sapiens
NATTGTTCGGK
MCCGAACAATN		 SELEX
Yin et al.(2017)
SOX12_eDBD_HT-SELEX 		0.435 0.828
SOX12
M05790_2.00 		Homo sapiens
YATTGTTCBKT
AMVGAACAATR		 SELEX
Yin et al.(2017)
SOX12_eDBD_Methyl-HT-SELEX 		0.435 0.828
For this family, TFs with SR scores > 0.415 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000322568 Sox 32 89

Links

Other Sox family TFs
Other Macaca fascicularis TFs

239 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CAA46607 Xenopus laevis CAA46607 N 0.643
ENSLOCG00000011834 Lepisosteus oculatus ENSLOCG00000011834 I 0.581
SOX8 Equus caballus ENSECAG00000016320 I 0.571
ENSSTOG00000011011 Ictidomys tridecemlineatus ENSSTOG00000011011 I 0.568
ACOM029353 Anopheles coluzzii ACOM029353 I 0.568
ENSOARG00000000906 Ovis aries ENSOARG00000000906 I 0.568
ENSPANG00000005859 Papio anubis ENSPANG00000005859 I 0.568
SMU15030186 Schmidtea mediterranea SMU15030186 N 0.565
sox-2 Caenorhabditis elegans WBGene00004949 I 0.562
LDEC019307 Leptinotarsa decemlineata LDEC019307 N 0.562
Myotis_brandtii_SOX2_10019709 Myotis brandtii Myotis_brandtii_SOX2_10019709 I 0.562
AMEC000538 Anopheles melas AMEC000538 I 0.562
Hba_21281 Heterorhabditis bacteriophora Hba_21281 N 0.562
Ogr08337 Ophisaurus gracilis Ogr08337 N 0.562
GPLIN_000970900 Globodera pallida GPLIN_000970900 N 0.562
GPLIN_000596700 Globodera pallida GPLIN_000596700 I 0.546
L798_12049 Zootermopsis nevadensis L798_12049 I 0.534
T265_14506 Opisthorchis viverrini T265_14506 I 0.529
TRE_0000259001 Trichobilharzia regenti TRE_0000259001 N 0.529
PXEA_0002992801 Protopolystoma xenopodis PXEA_0002992801 N 0.529
Sjc_0107520 Schistosoma japonicum Sjc_0107520 N 0.529
csin108932 Clonorchis sinensis csin108932 I 0.529
PPAI003639 Phlebotomus papatasi PPAI003639 N 0.529
MESCA012239 Megaselia scalaris MESCA012239 I 0.528
Brh_R004116 Buceros rhinoceros Brh_R004116 N 0.521
SPER_0001952401 Spirometra erinaceieuropaei SPER_0001952401 N 0.520
SPER_0001708101 Spirometra erinaceieuropaei SPER_0001708101 N 0.520
SOX12 Dasypus novemcinctus ENSDNOG00000044763 N 0.517
XP_002935940 Xenopus tropicalis XP_002935940 N 0.514
ENSPFOG00000012053 Poecilia formosa ENSPFOG00000012053 I 0.505
ENSPFOG00000005249 Poecilia formosa ENSPFOG00000005249 I 0.505
ENSPFOG00000012067 Poecilia formosa ENSPFOG00000012067 I 0.505
ENSPFOG00000002161 Poecilia formosa ENSPFOG00000002161 I 0.505
ENSPMAG00000010343 Petromyzon marinus ENSPMAG00000010343 I 0.505
Sox11 Rattus norvegicus ENSRNOG00000030034 I 0.505
SOX4 Pan troglodytes ENSPTRG00000029832 I 0.505
SOX11 Pan troglodytes ENSPTRG00000011625 I 0.505
ENSPSIG00000000182 Pelodiscus sinensis ENSPSIG00000000182 I 0.505
ENSPPYG00000016272 Pongo abelii ENSPPYG00000016272 I 0.505
ENSPANG00000018431 Papio anubis ENSPANG00000018431 I 0.505
SOX11 Oryctolagus cuniculus ENSOCUG00000027610 I 0.505
ENSOARG00000014622 Ovis aries ENSOARG00000014622 I 0.505
ENSOARG00000009518 Ovis aries ENSOARG00000009518 I 0.505
ENSOANG00000011128 Ornithorhynchus anatinus ENSOANG00000011128 I 0.505
SOX11 Otolemur garnettii ENSOGAG00000017044 I 0.505
SOX4 Otolemur garnettii ENSOGAG00000033507 I 0.505
ENSSHAG00000011043 Sarcophilus harrisii ENSSHAG00000011043 I 0.505
sox11a Oryzias latipes ENSORLG00000014996 I 0.505
ENSONIG00000020780 Oreochromis niloticus ENSONIG00000020780 I 0.505
ENSONIG00000020631 Oreochromis niloticus ENSONIG00000020631 I 0.505
SOX11 Procavia capensis ENSPCAG00000014259 I 0.505
SOX4 Sus scrofa ENSSSCG00000001081 I 0.505
Alligator_sinensis_CCG020314.1 Alligator sinensis Alligator_sinensis_CCG020314.1 I 0.505
Cmyd_10011923 Chelonia mydas Cmyd_10011923 I 0.505
Afo_R015773 Aptenodytes forsteri Afo_R015773 I 0.505
Afo_R012670 Aptenodytes forsteri Afo_R012670 N 0.505
Aan_R007717 Calypte anna Aan_R007717 I 0.505
Cmyd_10021727 Chelonia mydas Cmyd_10021727 I 0.505
Gfo_R002926 Geospiza fortis Gfo_R002926 I 0.505
Pvit_05105 Pogona vitticeps Pvit_05105 I 0.505
Ogr05236 Ophisaurus gracilis Ogr05236 I 0.505
Ogr03466 Ophisaurus gracilis Ogr03466 I 0.505
AAG17026 Xenopus laevis AAG17026 I 0.505
BAE47507 Xenopus laevis BAE47507 I 0.505
ENSNLEG00000001795 Nomascus leucogenys ENSNLEG00000001795 I 0.505
sox4b Tetraodon nigroviridis ENSTNIG00000009265 I 0.505
sox11a Tetraodon nigroviridis ENSTNIG00000017304 I 0.505
SOX11 Taeniopygia guttata ENSTGUG00000012987 I 0.505
sox4.L Xenopus laevis XB-GENE-865404 I 0.505
Pvit_03600 Pogona vitticeps Pvit_03600 I 0.505
sox11a Takifugu rubripes ENSTRUG00000003243 I 0.505
sox4.S Xenopus laevis XB-GENE-6253110 I 0.505
sox4 Xenopus tropicalis XB-GENE-480727 I 0.505
ENSXMAG00000020179 Xiphophorus maculatus ENSXMAG00000020179 I 0.505
ENSXMAG00000019759 Xiphophorus maculatus ENSXMAG00000019759 I 0.505
sox4b Takifugu rubripes ENSTRUG00000011266 I 0.505
ENSSHAG00000012040 Sarcophilus harrisii ENSSHAG00000012040 I 0.505
SOX11 Sus scrofa ENSSSCG00000008649 I 0.505
ENSDORG00000006502 Dipodomys ordii ENSDORG00000006502 I 0.505
SOX4 Erinaceus europaeus ENSEEUG00000003666 I 0.505
SOX11 Dasypus novemcinctus ENSDNOG00000048839 I 0.505
sox4b Danio rerio ENSDARG00000098834 I 0.505
ENSACAG00000011390 Anolis carolinensis ENSACAG00000011390 I 0.505
ENSFALG00000013518 Ficedula albicollis ENSFALG00000013518 I 0.505
ENSFALG00000014554 Ficedula albicollis ENSFALG00000014554 I 0.505
SOX4 Gorilla gorilla ENSGGOG00000012319 I 0.505
SOX11 Gorilla gorilla ENSGGOG00000025579 I 0.505
ENSGALG00000016397 Gallus gallus ENSGALG00000016397 I 0.505
SOX11 Homo sapiens ENSG00000176887 D 0.505
SOX4 Homo sapiens ENSG00000124766 D 0.505
Sox4 Mus musculus ENSMUSG00000076431 D 0.505
sox11a Danio rerio ENSDARG00000077811 I 0.505
SOX4 Bos taurus ENSBTAG00000046556 I 0.505
SOX4 Callithrix jacchus ENSCJAG00000007416 I 0.505
ENSAPLG00000005818 Anas platyrhynchos ENSAPLG00000005818 I 0.505
ENSAPLG00000002761 Anas platyrhynchos ENSAPLG00000002761 I 0.505
ENSACAG00000003013 Anolis carolinensis ENSACAG00000003013 I 0.505
SOX11 Callithrix jacchus ENSCJAG00000011595 I 0.505
SOX11 Cavia porcellus ENSCPOG00000019507 I 0.505
sox4a Danio rerio ENSDARG00000004588 I 0.505
ENSCSAG00000019105 Chlorocebus sabaeus ENSCSAG00000019105 I 0.505
ENSCSAG00000000373 Chlorocebus sabaeus ENSCSAG00000000373 I 0.505
ENSCPOG00000019926 Cavia porcellus ENSCPOG00000019926 I 0.505
ENSGMOG00000001228 Gadus morhua ENSGMOG00000001228 I 0.505
ENSAMEG00000011155 Ailuropoda melanoleuca ENSAMEG00000011155 I 0.505
ENSLACG00000014788 Latimeria chalumnae ENSLACG00000014788 I 0.505
ENSLOCG00000018008 Lepisosteus oculatus ENSLOCG00000018008 I 0.505
SOX4 Macaca mulatta ENSMMUG00000014454 I 0.505
SOX11 Loxodonta africana ENSLAFG00000006327 I 0.505
SOX4 Loxodonta africana ENSLAFG00000018401 I 0.505
ENSMMUG00000009344 Macaca mulatta ENSMMUG00000009344 I 0.505
ENSLOCG00000018338 Lepisosteus oculatus ENSLOCG00000018338 I 0.505
ENSMEUG00000016448 Macropus eugenii ENSMEUG00000016448 I 0.505
SOX11 Monodelphis domestica ENSMODG00000014575 I 0.505
Sox11 Mus musculus ENSMUSG00000063632 D 0.505
ENSLACG00000003899 Latimeria chalumnae ENSLACG00000003899 I 0.505
SOX4 Monodelphis domestica ENSMODG00000011338 I 0.505
ENSMPUG00000004933 Mustela putorius furo ENSMPUG00000004933 I 0.505
Myotis_brandtii_SOX12_10009951 Myotis brandtii Myotis_brandtii_SOX12_10009951 I 0.504
ENSPMAG00000010355 Petromyzon marinus ENSPMAG00000010355 I 0.501
ENSONIG00000020748 Oreochromis niloticus ENSONIG00000020748 I 0.499
ENSXMAG00000009656 Xiphophorus maculatus ENSXMAG00000009656 I 0.499
AAY98914 Xenopus tropicalis AAY98914 I 0.499
sox11 Xenopus tropicalis XB-GENE-483418 I 0.499
ENSAMXG00000025426 Astyanax mexicanus ENSAMXG00000025426 I 0.499
sox4 Oryzias latipes ENSORLG00000005001 I 0.499
sox11.S Xenopus laevis XB-GENE-483422 I 0.499
sox4a Tetraodon nigroviridis ENSTNIG00000009619 I 0.499
sox4a Gasterosteus aculeatus ENSGACG00000006620 I 0.499
ENSPFOG00000016372 Poecilia formosa ENSPFOG00000016372 I 0.499
sox11.L Xenopus laevis XB-GENE-6252061 I 0.499
GPLIN_001405800 Globodera pallida GPLIN_001405800 I 0.498
gw.110.115.1 Branchiostoma floridae gw.110.115.1 N 0.497
sox5.S Xenopus laevis XB-GENE-865667 I 0.497
sox13.S Xenopus laevis XB-GENE-865496 I 0.497
Gfo_R006305 Geospiza fortis Gfo_R006305 I 0.495
PFICI_02946 Pestalotiopsis fici PFICI_02946 N 0.495
XP_002170844.1 Hydra magnipapillata XP_002170844.1 I 0.493
CFIO01_04514 Colletotrichum fioriniae CFIO01_04514 N 0.491
PEX1_064750 Penicillium expansum PEX1_064750 N 0.490
PXEA_0000763901 Protopolystoma xenopodis PXEA_0000763901 N 0.490
PDIP_33190 Penicillium digitatum PDIP_33190 N 0.490
CAA46605 Xenopus laevis CAA46605 N 0.489
A1O9_05704 Exophiala aquamarina A1O9_05704 N 0.487
ENSOANG00000002448 Ornithorhynchus anatinus ENSOANG00000002448 I 0.487
DRE_00029 Drechslerella stenobrocha DRE_00029 N 0.486
AOL_s00081g337 Arthrobotrys oligospora AOL_s00081g337 N 0.486
TTAC_0001064401 Hydatigera taeniaeformis TTAC_0001064401 N 0.482
H072_9933 Dactylellina haptotyla H072_9933 N 0.478
sox11b Danio rerio ENSDARG00000095743 I 0.478
HYDPIDRAFT_51400 Hydnomerulius pinastri HYDPIDRAFT_51400 N 0.478
ENSAMXG00000001703 Astyanax mexicanus ENSAMXG00000001703 I 0.478
GLOINDRAFT_323774 Rhizophagus irregularis GLOINDRAFT_323774 N 0.477
GYMLUDRAFT_143012 Gymnopus luxurians GYMLUDRAFT_143012 N 0.474
sox4b Gasterosteus aculeatus ENSGACG00000009053 I 0.473
SOX11 Equus caballus ENSECAG00000013507 I 0.472
ENSONIG00000018824 Oreochromis niloticus ENSONIG00000018824 I 0.472
maker-nMf.1.1.scaf00287-augustus-gene-0.13 Meloidogyne floridensis maker-nMf.1.1.scaf00287-augustus-gene-0.13 I 0.470
ENSLOCG00000018365 Lepisosteus oculatus ENSLOCG00000018365 I 0.466
ENSLACG00000007378 Latimeria chalumnae ENSLACG00000007378 I 0.466
GLOINDRAFT_83691 Rhizophagus irregularis GLOINDRAFT_83691 N 0.466
sox12 Danio rerio ENSDARG00000025847 I 0.466
ENSAMXG00000025593 Astyanax mexicanus ENSAMXG00000025593 I 0.466
HMEL006651 Heliconius melpomene HMEL006651 I 0.464
HMEL002398 Heliconius melpomene HMEL002398 I 0.464
ENSAMXG00000025163 Astyanax mexicanus ENSAMXG00000025163 I 0.462
AMEM007694 Anopheles merus AMEM007694 N 0.458
SOX2 Felis catus ENSFCAG00000029205 I 0.458
SOX2 Procavia capensis ENSPCAG00000003690 I 0.458
YQE_08562 Dendroctonus ponderosae YQE_08562 N 0.458
UCREL1_469 Eutypa lata UCREL1_469 N 0.457
fgenesh1_pg.C_scaffold_11000031 Sporobolomyces roseus fgenesh1_pg.C_scaffold_11000031 N 0.456
UCREL1_749 Eutypa lata UCREL1_749 N 0.456
SERLA73DRAFT_139986 Serpula lacrymans SERLA73DRAFT_139986 N 0.454
PTTG_00444 Puccinia triticina PTTG_00444 N 0.452
sox12 Xenopus tropicalis XB-GENE-483252 I 0.451
sox12.S Xenopus laevis XB-GENE-864958 I 0.451
WALSEDRAFT_27096 Wallemia sebi WALSEDRAFT_27096 N 0.447
RPRC013413 Rhodnius prolixus RPRC013413 N 0.444
POSPLDRAFT_104634 Postia placenta POSPLDRAFT_104634 N 0.442
SOX4 Choloepus hoffmanni ENSCHOG00000002300 I 0.441
ENSAMEG00000013354 Ailuropoda melanoleuca ENSAMEG00000013354 I 0.441
e_gw.60.194.1 Branchiostoma floridae e_gw.60.194.1 N 0.438
WALSEDRAFT_59420 Wallemia sebi WALSEDRAFT_59420 N 0.438
ENSAMXG00000017231 Astyanax mexicanus ENSAMXG00000017231 I 0.437
SVUK_0000774301 Strongylus vulgaris SVUK_0000774301 I 0.436
GD15457 Drosophila simulans FBgn0187124 I 0.436
GH20178 Drosophila grimshawi FBgn0127642 I 0.436
SOX12 Tursiops truncatus ENSTTRG00000008502 I 0.435
ENSPANG00000001811 Papio anubis ENSPANG00000001811 I 0.435
ENSFALG00000014163 Ficedula albicollis ENSFALG00000014163 I 0.435
ENSPSIG00000001278 Pelodiscus sinensis ENSPSIG00000001278 I 0.435
ENSSHAG00000004381 Sarcophilus harrisii ENSSHAG00000004381 I 0.435
Sox12 Rattus norvegicus ENSRNOG00000007514 I 0.435
SOX12 Pteropus vampyrus ENSPVAG00000000181 I 0.435
SOX12 Homo sapiens ENSG00000177732 D 0.435
ENSPPYG00000010870 Pongo abelii ENSPPYG00000010870 I 0.435
ENSDNOG00000032024 Dasypus novemcinctus ENSDNOG00000032024 I 0.435
ENSCPOG00000010342 Cavia porcellus ENSCPOG00000010342 I 0.435
Alligator_sinensis_CCG000354.1 Alligator sinensis Alligator_sinensis_CCG000354.1 I 0.435
ENSCSAG00000018762 Chlorocebus sabaeus ENSCSAG00000018762 I 0.435
Cmyd_10009557 Chelonia mydas Cmyd_10009557 I 0.435
SOX12 Monodelphis domestica ENSMODG00000019507 I 0.435
Pvit_00226 Pogona vitticeps Pvit_00226 I 0.435
Sox12 Mus musculus ENSMUSG00000051817 D 0.435
SOX12 Otolemur garnettii ENSOGAG00000024255 I 0.435
SOX12 Canis familiaris ENSCAFG00000006973 I 0.435
ENSAMEG00000014001 Ailuropoda melanoleuca ENSAMEG00000014001 I 0.435
SOX12 Anolis carolinensis ENSACAG00000008177 I 0.435
L798_12872 Zootermopsis nevadensis L798_12872 I 0.434
KGM_02104 Danaus plexippus KGM_02104 I 0.434
BGIBMGA004151 Bombyx mori BGIBMGA004151 I 0.434
PLICRDRAFT_78649 Plicaturopsis crispa PLICRDRAFT_78649 N 0.434
SOX4 Canis familiaris ENSCAFG00000024883 I 0.434
SPU_002603 Strongylocentrotus purpuratus SPU_002603 I 0.432
GLOINDRAFT_25375 Rhizophagus irregularis GLOINDRAFT_25375 N 0.432
MCOS_0000919201 Mesocestoides corti MCOS_0000919201 N 0.431
sox9a Tetraodon nigroviridis ENSTNIG00000001901 N 0.431
ASTEI09242 Anopheles stephensi ASTEI09242 I 0.430
AMIN007346 Anopheles minimus AMIN007346 I 0.430
AGAP005183 Anopheles gambiae AGAP005183 I 0.430
ADIR001558 Anopheles dirus ADIR001558 I 0.430
AMEC017169 Anopheles melas AMEC017169 I 0.430
AARA002996 Anopheles arabiensis AARA002996 I 0.430
D915_11240 Fasciola hepatica D915_11240 N 0.428
SBAD_0000333601 Soboliphyme baturini SBAD_0000333601 I 0.428
ACHR008996 Anopheles christyi ACHR008996 N 0.426
RPRC001038 Rhodnius prolixus RPRC001038 N 0.425
MESCA006364 Megaselia scalaris MESCA006364 N 0.425
ENSCING00000007901 Ciona intestinalis ENSCING00000007901 I 0.424
CNM02020 Cryptococcus neoformans CNM02020 N 0.424
Thaps7519 Thalassiosira pseudonana Thaps7519 N 0.423
SMTD_0000090701 Schistosoma mattheei SMTD_0000090701 N 0.423
GLOINDRAFT_346686 Rhizophagus irregularis GLOINDRAFT_346686 N 0.421
nRc.2.0.1.g23945 Romanomermis culicivorax nRc.2.0.1.g23945 I 0.421
ENSAMXG00000003325 Astyanax mexicanus ENSAMXG00000003325 N 0.420
Smp_155690 Schistosoma mansoni Smp_155690 I 0.419
SMTD_0000255001 Schistosoma mattheei SMTD_0000255001 I 0.419
SROB_0000452001 Schistosoma rodhaini SROB_0000452001 I 0.419