Six3 (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000038805 T212499_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six3
M00483_2.00		 Mus musculus
NNNAYMN
NKRTNNN		 PBM
Berger et al.(2008)
Six3_1732		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SIX3
M05159_2.00 		Homo sapiens
NNYGATABBN
NVVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX 		0.867 1.000
SIX3
M10698_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX3_Q6 		0.867 1.000
SIX3
M05160_2.00 		Homo sapiens
NNYGATABVB
VBVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX 		0.867 1.000
Optix
M02124_2.00 		Drosophila melanogaster
NNNNNDATMN
NKATHNNNNN		 PBM
Weirauch et al.(2014)
pTH5437 		0.867 0.947
Optix
M03850_2.00 		Drosophila melanogaster
TAATYTAATTA
TAATTARATTA		 SELEX
Nitta et al.(2015)
Optix_1 		0.867 0.947
Optix
M06526_2.00 		Drosophila melanogaster
TGATA
TATCA		 B1H
Mathelier et al.(2014)
MA0199.1 		0.867 0.947
Optix
M06327_2.00 		Drosophila melanogaster
HHVTGATA
TATCABDD		 B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360 		0.867 0.947
Optix
M06328_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360 		0.867 0.947
SIX6
M00326_2.00 		Homo sapiens
NNDATMB
VKATHNN		 PBM
Barrera et al.(2016)
SIX6_REF 		0.865 0.982
Six6
M00169_2.00 		Mus musculus
NNAYMNN
NNKRTNN		 PBM
Badis et al.(2009)
Six6_2267 		0.865 0.982
Six6
M00412_2.00 		Mus musculus
NNNTGATAYCN
NGRTATCANNN		 PBM
Berger et al.(2008)
Six6_2267 		0.865 0.982
SIX6
M05357_2.00 		Homo sapiens
NNYGATASVB
VBSTATCRNN		 SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX 		0.865 0.982
SIX6
M00325_2.00 		Homo sapiens
NNNDATMB
VKATHNNN		 PBM
Barrera et al.(2016)
SIX6_H141N 		0.865 0.982
SIX6
M05358_2.00 		Homo sapiens
VBVYAYCRNN
NNYGRTRBVB		 SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX 		0.865 0.982
six3
M02102_2.00 		Oryzias latipes
NNDAYMBNNN
NNNVKRTHNN		 PBM
Weirauch et al.(2014)
pTH5928 		0.865 0.947
SIX6
M00327_2.00 		Homo sapiens
NHDAYMBNN
NNVKRTHDN		 PBM
Barrera et al.(2016)
SIX6_T165A 		0.859 0.965
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00483_2.00 Homeodomain 16 72

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000125169 Homeodomain 208 264
ENSMUSP00000135312 Homeodomain 208 264
ENSMUSP00000135677 Homeodomain 208 264

Links

Other Homeodomain family TFs
Other Mus musculus TFs

297 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
EIL3 Arabidopsis thaliana AT1G73730 D
OS09G0490200 Oryza sativa OS09G0490200 D
Traes_7BS_733347AC0 Triticum aestivum Traes_7BS_733347AC0 I
Aquca_007_00017 Aquilegia coerulea Aquca_007_00017 I
mgf020935m Mimulus guttatus mgf020935m I
Cucsa.143220 Cucumis sativus Cucsa.143220 I
cassava30700.valid.m1 Manihot esculenta cassava30700.valid.m1 I
cassava2120.valid.m1 Manihot esculenta cassava2120.valid.m1 I
30169.m006395 Ricinus communis 30169.m006395 I
Pm028171 Prunus mume Pm028171 I
Ca_02669 Cicer arietinum Ca_02669 I
EIL3 Vitis vinifera VIT_06s0004g01610 I
TRIUR3_28079 Triticum urartu TRIUR3_28079 I
TRIUR3_08597 Triticum urartu TRIUR3_08597 I
Traes_7DS_3673F1C73 Triticum aestivum Traes_7DS_3673F1C73 I
Bostr.3288s0016 Boechera stricta Bostr.3288s0016 I
Traes_7AS_34D476D5D1 Triticum aestivum Traes_7AS_34D476D5D1 I
Traes_5DL_62DEF8361 Triticum aestivum Traes_5DL_62DEF8361 I
Traes_5BL_B6051DD37 Triticum aestivum Traes_5BL_B6051DD37 I
Traes_5AL_B65EF5518 Triticum aestivum Traes_5AL_B65EF5518 I
Traes_4BL_F34EBD618 Triticum aestivum Traes_4BL_F34EBD618 I
TCM_040510 Theobroma cacao TCM_040510 I
Solyc01g014480.2 Solanum lycopersicum Solyc01g014480.2 I
Solyc01g006650.1 Solanum lycopersicum Solyc01g006650.1 I
Si029259m.g Setaria italica Si029259m.g I
Si013426m.g Setaria italica Si013426m.g I
MDP0000565880 Malus domestica MDP0000565880 I
PDK_20s1301801g002 Phoenix dactylifera PDK_20s1301801g002 I
chr3.LjB09K03.50.nc Lotus japonicus chr3.LjB09K03.50.nc I
PK19114.1 Cannabis sativa PK19114.1 I
Thhalv10018327m.g Eutrema salsugineum Thhalv10018327m.g I
SapurV1A.0850s0030 Salix purpurea SapurV1A.0850s0030 I
SapurV1A.0009s0320 Salix purpurea SapurV1A.0009s0320 I
Pavir.J14329 Panicum virgatum Pavir.J14329 I
Pavir.J02229 Panicum virgatum Pavir.J02229 I
Pavir.Fb01951 Panicum virgatum Pavir.Fb01951 I
Pavir.Fa00424 Panicum virgatum Pavir.Fa00424 I
orange1.1g007662m.g Citrus sinensis orange1.1g007662m.g I
Sb07g027790 Sorghum bicolor Sb07g027790 I
MDP0000562585 Malus domestica MDP0000562585 I
MDP0000490180 Malus domestica MDP0000490180 I
Lus10031817.g Linum usitatissimum Lus10031817.g I
Lus10031245.g Linum usitatissimum Lus10031245.g I
Gorai.010G128700 Gossypium raimondii Gorai.010G128700 I
Gorai.009G071400 Gossypium raimondii Gorai.009G071400 I
gene20650-v1.0-hybrid Fragaria vesca gene20650-v1.0-hybrid I
Eucgr.B03664 Eucalyptus grandis Eucgr.B03664 I
Ciclev10015261m.g Citrus clementina Ciclev10015261m.g I
Carubv10020043m.g Capsella rubella Carubv10020043m.g I
Cagra.0876s0005 Capsella grandiflora Cagra.0876s0005 I
GRMZM2G006752 Zea mays GRMZM2G006752 I
OBART08G19960 Oryza barthii OBART08G19960 I
OB09G21280 Oryza brachyantha OB09G21280 I
OB08G26880 Oryza brachyantha OB08G26880 I
MTR_2g098470 Medicago truncatula MTR_2g098470 I
MLOC_10823 Hordeum vulgare MLOC_10823 I
MLOC_10315 Hordeum vulgare MLOC_10315 I
LPERR09G10870 Leersia perrieri LPERR09G10870 I
LPERR08G16890 Leersia perrieri LPERR08G16890 I
GSMUA_Achr9G27680_001 Musa acuminata GSMUA_Achr9G27680_001 I
GSMUA_Achr8G25580_001 Musa acuminata GSMUA_Achr8G25580_001 I
GSMUA_Achr3G11160_001 Musa acuminata GSMUA_Achr3G11160_001 I
OBART09G14750 Oryza barthii OBART09G14750 I
GLYMA15G03650 Glycine max GLYMA15G03650 I
GLYMA13G41751 Glycine max GLYMA13G41751 I
F775_17920 Aegilops tauschii F775_17920 I
BRADI3G39970 Brachypodium distachyon BRADI3G39970 I
Bra015970 Brassica rapa Bra015970 I
Bra008110 Brassica rapa Bra008110 I
Bo6g118030 Brassica oleracea Bo6g118030 I
Bo6g087550 Brassica oleracea Bo6g087550 I
BGIOSGA029545 Oryza indica BGIOSGA029545 I
BGIOSGA026709 Oryza indica BGIOSGA026709 I
AMTR_s00022p00216890 Amborella trichopoda AMTR_s00022p00216890 I
ORGLA09G0113600 Oryza glaberrima ORGLA09G0113600 I
AC234203.1_FG011 Zea mays AC234203.1_FG011 I
Sb02g028390 Sorghum bicolor Sb02g028390 I
PRUPE_ppa003113mg Prunus persica PRUPE_ppa003113mg I
POPTR_0003s22090 Populus trichocarpa POPTR_0003s22090 I
POPTR_0001s05370 Populus trichocarpa POPTR_0001s05370 I
POPTR_0001s05360 Populus trichocarpa POPTR_0001s05360 I
PGSC0003DMG400029908 Solanum tuberosum PGSC0003DMG400029908 I
PGSC0003DMG400021381 Solanum tuberosum PGSC0003DMG400021381 I
OS08G0508700 Oryza sativa OS08G0508700 I
ORUFI09G15900 Oryza rufipogon ORUFI09G15900 I
ORUFI08G22370 Oryza rufipogon ORUFI08G22370 I
EIL3 Arabidopsis lyrata scaffold_202309.1 I
OPUNC09G13210 Oryza punctata OPUNC09G13210 I
OPUNC08G18080 Oryza punctata OPUNC08G18080 I
ONIVA08G22530 Oryza nivara ONIVA08G22530 I
ONIVA08G17420 Oryza nivara ONIVA08G17420 I
OMERI09G11470 Oryza meridionalis OMERI09G11470 I
OMERI08G16770 Oryza meridionalis OMERI08G16770 I
OMERI05G02190 Oryza meridionalis OMERI05G02190 I
OLONG_020705 Oryza longistaminata OLONG_020705 I
OGLUM09G15380 Oryza glumaepatula OGLUM09G15380 I
OGLUM08G21190 Oryza glumaepatula OGLUM08G21190 I
OLONG_023247 Oryza longistaminata OLONG_023247 N