CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

irf6 *(Xenopus tropicalis)* IRF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00605 (IRF)	IPR001346	XB-GENE-876410	T244625_2.00	Misc (2018-Jan-19)
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
irf6.2 M02259_2.00	Xenopus tropicalis	NVNHGAWACH	DGTWTCDNBN	PBM Weirauch et al.(2014) pTH9302	0.962	0.962
IRF6 M02254_2.00	Meleagris gallopavo	NRNCGAWACY	RGTWTCGNYN	PBM Weirauch et al.(2014) pTH9210	0.952	0.952
IRF6 M02253_2.00	Gallus gallus	NNMCNAAWNN	NNWTTNGKNN	PBM Weirauch et al.(2014) pTH9178	0.943	0.943
Irf6 M00176_2.00	Mus musculus	NNNHGADASN	NSTHTCDNNN	PBM Badis et al.(2009) Irf6_3803	0.895	0.895
IRF6 M05527_2.00	Homo sapiens	RGTWTCGNNNNNNYGAWACY	RGTWTCRNNNNNNCGAWACY	SELEX Yin et al.(2017) IRF6_eDBD_HT-SELEX	0.895	0.895
IRF6 M05529_2.00	Homo sapiens	ACCGAAACT	AGTTTCGGT	SELEX Yin et al.(2017) IRF6_FL_HT-SELEX	0.895	0.895
IRF6 M05528_2.00	Homo sapiens	RGTWTCGNHNNDNYGAWACY	RGTWTCRNHNNDNCGAWACY	SELEX Yin et al.(2017) IRF6_eDBD_Methyl-HT-SELEX	0.895	0.895
IRF6 M05530_2.00	Homo sapiens	ACCGAWACY	RGTWTCGGT	SELEX Yin et al.(2017) IRF6_FL_Methyl-HT-SELEX	0.905	0.905
irf5.L M02260_2.00	Xenopus laevis	VNCGADACHN	NDGTHTCGNB	PBM Weirauch et al.(2014) pTH9367	0.743	0.743
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
AAI58988	IRF	9	114	RLKPWLVAQVDSGMYPGLIWLNREAKMFQIPWKHATRHSPQQEEEKTIFKAWAVETGKYQEGADEPDPAKWKAQLRCALNKSREFKLMYDGTKEVPMNPVKIYEVR
CAJ83506	IRF	9	114	RLKPWLVAQVDSGMYPGLIWLNREAKRFQIPWKHATRHSPQQEEEKTIFKAWAVETGKYQEGADEPDPAKWKAQLRCALNKSREFKLMYDGTKEVPMNPVKIYEVR

Links
Other IRF family TFs
Other *Xenopus tropicalis* TFs