HHAL005991-PA (Halyomorpha halys)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 HHAL005991-PA T144067_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
lin-48
M00614_2.00 		Caenorhabditis elegans
HCCGTTAB
VTAACGGD		 PBM
Narasimhan et al.(2015)
pTH9155 		0.809 0.855
ovo
M03669_2.00 		Drosophila melanogaster
DNMCCGTTA
TAACGGKNH		 SELEX
Nitta et al.(2015)
ovo_1 		0.797 0.928
ovo
M06064_2.00 		Drosophila melanogaster
CHGTTAHW
WDTAACDG		 B1H
Zhu et al.(2011)
ovo_FlyReg_FBgn0003028 		0.797 0.928
ovo
M06065_2.00 		Drosophila melanogaster
RGTHCCGTTAT
ATAACGGDACY		 B1H
Zhu et al.(2011)
ovo_SANGER_5_FBgn0003028 		0.797 0.928
ovo
M06066_2.00 		Drosophila melanogaster
DDTMCCGTTABNYN
NRNVTAACGGKAHH		 B1H
Zhu et al.(2011)
ovo_SOLEXA_5_FBgn0003028 		0.797 0.928
ovo
M02671_2.00 		Drosophila melanogaster
DCNGTTWSD
HSWAACNGH		 SELEX
Mathelier et al.(2014)
MA0126.1 		0.797 0.928
ovo
M09662_2.00 		Drosophila melanogaster
DCNGTTAMWNNDV
BHNNWKTAACNGH		 Misc
Kulakovskiy et al.(2009)
ovo 		0.797 0.928
ovo
M10373_2.00 		Drosophila melanogaster
NNNDCNGTTWSDDNN
NNHHSWAACNGHNNN		 Transfac
Matys et al.(2006)
I$OVO_01 		0.797 0.928
ovo
M10374_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$OVO_Q6 		0.797 0.928
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL005991-PA C2H2 ZF 58 80
HHAL005991-PA C2H2 ZF 86 108
HHAL005991-PA C2H2 ZF 114 137

Links

Other C2H2 ZF family TFs
Other Halyomorpha halys TFs

69 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CLEC002514 Cimex lectularius CLEC002514 I 0.827
RPRC002781 Rhodnius prolixus RPRC002781 I 0.827
GB51354 Apis mellifera GB51354 I 0.820
ACEP17857 Atta cephalotes ACEP17857 I 0.810
Cflo_08035--XP_624482.2_APIME Camponotus floridanus Cflo_08035--XP_624482.2_APIME I 0.810
SINV17081 Solenopsis invicta SINV17081 I 0.810
CRE25436 Caenorhabditis remanei CRE25436 I 0.809
lin-48 Caenorhabditis elegans WBGene00003033 D 0.809
CJA37604 Caenorhabditis japonica CJA37604 I 0.809
CJA03277 Caenorhabditis japonica CJA03277 I 0.809
CBG09216 Caenorhabditis briggsae CBG09216 I 0.809
ACYPI003064 Acyrthosiphon pisum ACYPI003064 I 0.808
Bm3814 Brugia malayi Bm3814 I 0.806
BTMF_0001741201 Brugia timori BTMF_0001741201 I 0.806
AAEL017521 Aedes aegypti AAEL017521 I 0.804
LCUP004963 Lucilia cuprina LCUP004963 I 0.804
AARA001055 Anopheles arabiensis AARA001055 I 0.804
ADAC004491 Anopheles darlingi ADAC004491 I 0.804
PHUM086430 Pediculus humanus PHUM086430 I 0.804
AATE002741 Anopheles atroparvus AATE002741 I 0.804
BGIBMGA000988 Bombyx mori BGIBMGA000988 I 0.804
AFUN010393 Anopheles funestus AFUN010393 I 0.804
ASIS014406 Anopheles sinensis ASIS014406 I 0.804
ASTEI07557 Anopheles stephensi ASTEI07557 I 0.804
PPAI008669 Phlebotomus papatasi PPAI008669 I 0.804
AMEM014020 Anopheles merus AMEM014020 I 0.804
AMEC022552 Anopheles melas AMEC022552 I 0.804
ACUA027175 Anopheles culicifacies ACUA027175 I 0.804
ADIR001008 Anopheles dirus ADIR001008 I 0.804
MCINX009401 Melitaea cinxia MCINX009401 I 0.804
ACHR004136 Anopheles christyi ACHR004136 I 0.804
CpipJ_CPIJ018505 Culex pipiens CpipJ_CPIJ018505 I 0.804
HMEL006827 Heliconius melpomene HMEL006827 I 0.804
CPIJ018505 Culex quinquefasciatus CPIJ018505 I 0.804
L798_11303 Zootermopsis nevadensis L798_11303 I 0.804
KGM_02259 Danaus plexippus KGM_02259 I 0.804
AGAP000114 Anopheles gambiae AGAP000114 I 0.804
LDEC009536 Leptinotarsa decemlineata LDEC009536 I 0.800
TC008099 Tribolium castaneum TC008099 I 0.800
GL26817 Drosophila persimilis FBgn0164398 I 0.797
GA22634 Drosophila pseudoobscura FBgn0244037 I 0.797
GE16381 Drosophila yakuba FBgn0233910 I 0.797
GK10250 Drosophila willistoni FBgn0212265 I 0.797
GM12381 Drosophila sechellia FBgn0167318 I 0.797
GD24377 Drosophila simulans FBgn0195718 I 0.797
GF20355 Drosophila ananassae FBgn0097362 I 0.797
ovo Drosophila melanogaster FBgn0003028 D 0.797
GH24684 Drosophila grimshawi FBgn0132140 I 0.797
ovo Drosophila virilis FBgn0064309 I 0.797
GI21666 Drosophila mojavensis FBgn0144396 I 0.797
GG18741 Drosophila erecta FBgn0110950 I 0.797
ISCW013547 Ixodes scapularis ISCW013547 I 0.796
CBN00506 Caenorhabditis brenneri CBN00506 I 0.793
SMAR006131 Strigamia maritima SMAR006131 I 0.793
L898_g2421 Steinernema monticolum L898_g2421 I 0.790
NECAME_03083 Necator americanus NECAME_03083 I 0.790
TELCIR_07985 Teladorsagia circumcincta TELCIR_07985 I 0.790
HCOI01936300 Haemonchus contortus HCOI01936300 I 0.790
CapteG147941 Capitella teleta CapteG147941 I 0.786
MDOA012259 Musca domestica MDOA012259 I 0.784
tetur12g02760 Tetranychus urticae tetur12g02760 I 0.780
tetur12g02740 Tetranychus urticae tetur12g02740 I 0.780
tetur12g02770 Tetranychus urticae tetur12g02770 I 0.780
tetur12g02810 Tetranychus urticae tetur12g02810 I 0.777
SPU_012448 Strongylocentrotus purpuratus SPU_012448 I 0.770
tetur12g02860 Tetranychus urticae tetur12g02860 I 0.770
tetur157g00030 Tetranychus urticae tetur157g00030 I 0.766
Sakowv30033343m.g Saccoglossus kowalevskii Sakowv30033343m.g I 0.766
SBAD_0001064501 Soboliphyme baturini SBAD_0001064501 I 0.761