nhr-102 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003692 T306214_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease (multiple); hepatocellular carcinoma; lipid metabolism disorder; and type 2 diabetes mellitus. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha) and PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-142
M00703_2.00 		Caenorhabditis elegans
RGTCACAR
YTGTGACY		 PBM
Narasimhan et al.(2015)
pTH10714 		0.837 0.586
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.824 0.543
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
T06C12.6 Nuclear receptor 22 94

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

50 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE08691 Caenorhabditis remanei CRE08691 I 0.987
CBG22870 Caenorhabditis briggsae CBG22870 I 0.981
nhr-178 Caenorhabditis elegans WBGene00017510 I 0.972
CBG06611 Caenorhabditis briggsae CBG06611 I 0.971
CBG06601 Caenorhabditis briggsae CBG06601 I 0.971
CRE18430 Caenorhabditis remanei CRE18430 I 0.971
nhr-213 Caenorhabditis elegans WBGene00011520 I 0.970
CJA09697 Caenorhabditis japonica CJA09697 I 0.957
NBR_0001218401 Nippostrongylus brasiliensis NBR_0001218401 I 0.946
HCOI00483700 Haemonchus contortus HCOI00483700 I 0.941
HPLM_0000277901 Haemonchus placei HPLM_0000277901 I 0.941
ANCCEY_13226 Ancylostoma ceylanicum ANCCEY_13226 I 0.941
ACOC_0000492601 Angiostrongylus costaricensis ACOC_0000492601 I 0.939
SVUK_0002058501 Strongylus vulgaris SVUK_0002058501 I 0.918
SVUK_0001603001 Strongylus vulgaris SVUK_0001603001 I 0.878
L596_g14586 Steinernema carpocapsae L596_g14586 I 0.853
augustus_masked-nMf.1.1.scaf21762-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf21762-processed-gene-0.0 I 0.850
CBG09320 Caenorhabditis briggsae CBG09320 I 0.849
CRE31070 Caenorhabditis remanei CRE31070 I 0.849
CBN21486 Caenorhabditis brenneri CBN21486 I 0.849
CBN28290 Caenorhabditis brenneri CBN28290 I 0.849
L898_g12798 Steinernema monticolum L898_g12798 I 0.848
Minc14668 Meloidogyne incognita Minc14668 I 0.842
CJA28065 Caenorhabditis japonica CJA28065 I 0.841
scaffold31-EXSNAP2012.20 Pristionchus exspectatus scaffold31-EXSNAP2012.20 I 0.840
nhr-142 Caenorhabditis elegans WBGene00018430 D 0.837
MhA1_Contig1192.frz3.gene3 Meloidogyne hapla MhA1_Contig1192.frz3.gene3 I 0.835
CRE30948 Caenorhabditis remanei CRE30948 I 0.835
CBG09567 Caenorhabditis briggsae CBG09567 I 0.833
GPLIN_000282900 Globodera pallida GPLIN_000282900 I 0.829
nhr-232 Caenorhabditis elegans WBGene00012494 D 0.824
HPBE_0001646201 Heligmosomoides bakeri HPBE_0001646201 I 0.800
CBG20729 Caenorhabditis briggsae CBG20729 I 0.799
nhr-54 Caenorhabditis elegans WBGene00003644 I 0.797
SMUV_0000241501 Syphacia muris SMUV_0000241501 N 0.791
CBN23838 Caenorhabditis brenneri CBN23838 I 0.787
CRE15644 Caenorhabditis remanei CRE15644 I 0.787
NBR_0001834701 Nippostrongylus brasiliensis NBR_0001834701 I 0.783
SMUV_0000241401 Syphacia muris SMUV_0000241401 I 0.781
CBG20727 Caenorhabditis briggsae CBG20727 I 0.776
HPLM_0000974401 Haemonchus placei HPLM_0000974401 I 0.775
CBG14515 Caenorhabditis briggsae CBG14515 I 0.773
CJA02156 Caenorhabditis japonica CJA02156 I 0.773
nhr-45 Caenorhabditis elegans WBGene00003635 I 0.773
CBN12210 Caenorhabditis brenneri CBN12210 I 0.773
CRE00301 Caenorhabditis remanei CRE00301 I 0.773
nhr-231 Caenorhabditis elegans WBGene00012449 I 0.765
CRE15675 Caenorhabditis remanei CRE15675 I 0.764
nhr-170 Caenorhabditis elegans WBGene00008309 I 0.750
EVEC_0000956701 Enterobius vermicularis EVEC_0000956701 I 0.749