nhr-170 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00008309 T306263_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-142
M00703_2.00 		Caenorhabditis elegans
RGTCACAR
YTGTGACY		 PBM
Narasimhan et al.(2015)
pTH10714 		0.885 0.543
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.793 0.471
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
C54E10.5 Nuclear receptor 15 86

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

69 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBN23838 Caenorhabditis brenneri CBN23838 I 0.984
CRE15644 Caenorhabditis remanei CRE15644 I 0.984
CBG20729 Caenorhabditis briggsae CBG20729 I 0.983
CRE15675 Caenorhabditis remanei CRE15675 I 0.982
CBG20727 Caenorhabditis briggsae CBG20727 I 0.982
nhr-231 Caenorhabditis elegans WBGene00012449 I 0.979
nhr-54 Caenorhabditis elegans WBGene00003644 I 0.974
CBN13569 Caenorhabditis brenneri CBN13569 I 0.960
L898_g3512 Steinernema monticolum L898_g3512 I 0.898
HPBE_0001646201 Heligmosomoides bakeri HPBE_0001646201 I 0.896
HCOI01190000 Haemonchus contortus HCOI01190000 I 0.893
HPLM_0000974301 Haemonchus placei HPLM_0000974301 I 0.893
nhr-142 Caenorhabditis elegans WBGene00018430 D 0.885
CBG22870 Caenorhabditis briggsae CBG22870 I 0.883
NBR_0001834701 Nippostrongylus brasiliensis NBR_0001834701 I 0.882
ACOC_0000492601 Angiostrongylus costaricensis ACOC_0000492601 I 0.881
CBN28290 Caenorhabditis brenneri CBN28290 I 0.880
CBN21486 Caenorhabditis brenneri CBN21486 I 0.880
SVUK_0002058501 Strongylus vulgaris SVUK_0002058501 I 0.876
HPLM_0000974401 Haemonchus placei HPLM_0000974401 I 0.866
L892_g2782 Steinernema scapterisci L892_g2782 I 0.857
NBR_0001218401 Nippostrongylus brasiliensis NBR_0001218401 I 0.852
L596_g14588 Steinernema carpocapsae L596_g14588 I 0.850
CRE30948 Caenorhabditis remanei CRE30948 I 0.846
CRE18430 Caenorhabditis remanei CRE18430 I 0.844
CBG06611 Caenorhabditis briggsae CBG06611 I 0.843
CBG06601 Caenorhabditis briggsae CBG06601 I 0.843
HCOI00483700 Haemonchus contortus HCOI00483700 I 0.842
HPLM_0000277901 Haemonchus placei HPLM_0000277901 I 0.842
ANCCEY_13226 Ancylostoma ceylanicum ANCCEY_13226 I 0.842
ANCCEY_07914 Ancylostoma ceylanicum ANCCEY_07914 I 0.835
nhr-213 Caenorhabditis elegans WBGene00011520 I 0.831
CBG09320 Caenorhabditis briggsae CBG09320 I 0.828
CRE31070 Caenorhabditis remanei CRE31070 I 0.828
CJA09697 Caenorhabditis japonica CJA09697 I 0.826
L892_g2781 Steinernema scapterisci L892_g2781 I 0.825
CBG09567 Caenorhabditis briggsae CBG09567 I 0.823
L596_g14586 Steinernema carpocapsae L596_g14586 I 0.823
SVUK_0001603001 Strongylus vulgaris SVUK_0001603001 I 0.816
L889_g6696 Steinernema feltiae L889_g6696 I 0.814
scaffold31-EXSNAP2012.20 Pristionchus exspectatus scaffold31-EXSNAP2012.20 I 0.812
CRE08750 Caenorhabditis remanei CRE08750 N 0.810
CBG06599 Caenorhabditis briggsae CBG06599 I 0.810
CBG06609 Caenorhabditis briggsae CBG06609 I 0.810
CJA28065 Caenorhabditis japonica CJA28065 I 0.808
nhr-178 Caenorhabditis elegans WBGene00017510 I 0.803
L898_g3514 Steinernema monticolum L898_g3514 I 0.798
L596_g14589 Steinernema carpocapsae L596_g14589 I 0.793
nhr-232 Caenorhabditis elegans WBGene00012494 D 0.793
CRE08691 Caenorhabditis remanei CRE08691 I 0.788
L893_g18992 Steinernema glaseri L893_g18992 I 0.787
L889_g6694 Steinernema feltiae L889_g6694 I 0.786
Minc14668 Meloidogyne incognita Minc14668 I 0.784
L596_g14590 Steinernema carpocapsae L596_g14590 I 0.783
augustus_masked-nMf.1.1.scaf21762-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf21762-processed-gene-0.0 I 0.779
CRE08749 Caenorhabditis remanei CRE08749 I 0.778
L893_g18997 Steinernema glaseri L893_g18997 I 0.777
MhA1_Contig1192.frz3.gene3 Meloidogyne hapla MhA1_Contig1192.frz3.gene3 I 0.776
L898_g3515 Steinernema monticolum L898_g3515 I 0.775
L596_g14536 Steinernema carpocapsae L596_g14536 I 0.771
L892_g14834 Steinernema scapterisci L892_g14834 N 0.764
L889_g6695 Steinernema feltiae L889_g6695 I 0.755
GPLIN_000282900 Globodera pallida GPLIN_000282900 I 0.753
L889_g6692 Steinernema feltiae L889_g6692 I 0.753
nhr-102 Caenorhabditis elegans WBGene00003692 I 0.750
L898_g4018 Steinernema monticolum L898_g4018 N 0.750
L596_g14596 Steinernema carpocapsae L596_g14596 I 0.749
L892_g2780 Steinernema scapterisci L892_g2780 I 0.749
L898_g12798 Steinernema monticolum L898_g12798 I 0.745