ISL1 (Loxodonta africana)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSLAFG00000017758 T211050_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Isl2
M00458_2.00 		Mus musculus
NWDWDNN
NNHWHWN		 PBM
Berger et al.(2008)
Isl2_3430 		0.867 1.000
ISL2
M03177_2.00 		Homo sapiens
YTAAKTGB
VCAMTTAR		 SELEX
Jolma et al.(2013)
ISL2_1 		0.867 1.000
ISL1
M04908_2.00 		Homo sapiens
BTAAKTGS
SCAMTTAV		 SELEX
Yin et al.(2017)
ISL1_eDBD_HT-SELEX 		0.867 1.000
ISL1
M04910_2.00 		Homo sapiens
NTAAKTGS
SCAMTTAN		 SELEX
Yin et al.(2017)
ISL1_FL_HT-SELEX 		0.867 1.000
ISL2
M05204_2.00 		Homo sapiens
NTAAKTGS
SCAMTTAN		 SELEX
Yin et al.(2017)
ISL2_eDBD_HT-SELEX 		0.867 1.000
ISL1
M09128_2.00 		Homo sapiens
NYWRAKKGV
BCMMTYWRN		 Misc
Kulakovskiy et al.(2013)
ISL1_HUMAN.H11MO.0.A 		0.867 1.000
Isl1
M09209_2.00 		Mus musculus
NYWRAKKGV
BCMMTYWRN		 Misc
Kulakovskiy et al.(2013)
ISL1_MOUSE.H11MO.0.A 		0.867 1.000
Isl1
M09578_2.00 		Mus musculus
YTAAKKGV
BCMMTTAR		 Misc
Heinz et al.(2010)
Neuron-Isl1_GSE31456 		0.867 1.000
ISL1
M10634_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL1_Q3 		0.867 1.000
ISL1
M10635_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL1_Q6 		0.867 1.000
ISL1
M04909_2.00 		Homo sapiens
BTAAKTGS
SCAMTTAV		 SELEX
Yin et al.(2017)
ISL1_eDBD_Methyl-HT-SELEX 		0.867 1.000
ISL1
M04911_2.00 		Homo sapiens
BTAAKTGS
SCAMTTAV		 SELEX
Yin et al.(2017)
ISL1_FL_Methyl-HT-SELEX 		0.867 1.000
ISL2
M05205_2.00 		Homo sapiens
NTAAKTGN
NCAMTTAN		 SELEX
Yin et al.(2017)
ISL2_eDBD_Methyl-HT-SELEX 		0.867 1.000
ISL2B_ONCTS
M10798_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_02 		0.866 0.982
ISL2B_ONCTS
M10799_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_03 		0.866 0.982
ISL2B_ONCTS
M10800_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_04 		0.866 0.982
ISL2B_ONCTS
M10801_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_05 		0.866 0.982
tup
M06498_2.00 		Drosophila melanogaster
WTAATKG
CMATTAW		 B1H
Mathelier et al.(2014)
MA0248.1 		0.864 0.965
tup
M06270_2.00 		Drosophila melanogaster
SWTAATKG
CMATTAWS		 B1H
Zhu et al.(2011)
Tup_Cell_FBgn0003896 		0.864 0.965
tup
M06271_2.00 		Drosophila melanogaster
NYTAATKRV
BYMATTARN		 B1H
Zhu et al.(2011)
tup_SOLEXA_10_FBgn0003896 		0.864 0.965
tup
M06272_2.00 		Drosophila melanogaster
YTAATKR
YMATTAR		 B1H
Zhu et al.(2011)
Tup_SOLEXA_FBgn0003896 		0.864 0.965
CBG04010
M01242_2.00 		Caenorhabditis briggsae
NNKTAATDDMN
NKHHATTAMNN		 PBM
Lambert et al.(2019)
pTH11489 		0.835 0.772
NEMVEDRAFT_v1g81309
M02152_2.00 		Nematostella vectensis
NTAATDNNN
NNNHATTAN		 PBM
Weirauch et al.(2014)
pTH5477 		0.636 0.351
NOTO
M03241_2.00 		Homo sapiens
NNTAATKWRN
NYWMATTANN		 SELEX
Jolma et al.(2013)
NOTO_1 		0.631 0.368
NOTO
M05390_2.00 		Homo sapiens
BTAATKRV
BYMATTAV		 SELEX
Yin et al.(2017)
NOTO_eDBD_HT-SELEX 		0.631 0.368
NOTO
M05391_2.00 		Homo sapiens
BTMATKRV
BYMATKAV		 SELEX
Yin et al.(2017)
NOTO_eDBD_Methyl-HT-SELEX 		0.631 0.368
PHOX2B
M00278_2.00 		Homo sapiens
NNNNNRY
RYNNNNN		 PBM
Barrera et al.(2016)
PHOX2B_Q143R 		0.623 0.368
Noto
M02101_2.00 		Mus musculus
NNHHATDDNN
NNHHATDDNN		 PBM
Weirauch et al.(2014)
pTH6268 		0.613 0.351
VSX1
M00269_2.00 		Homo sapiens
NNWAAYNNN
NNNRTTWNN		 PBM
Barrera et al.(2016)
VSX1_REF 		0.608 0.386
Vsx1
M00459_2.00 		Mus musculus
NNTAATDDN
NHHATTANN		 PBM
Berger et al.(2008)
Vsx1_1728 		0.608 0.386
Vsx1
M03267_2.00 		Mus musculus
NTAATTRN
NYAATTAN		 SELEX
Jolma et al.(2013)
Vsx1_1 		0.608 0.386
VSX1
M00266_2.00 		Homo sapiens
NNTAAYNNN
NNNRTTANN		 PBM
Barrera et al.(2016)
VSX1_G160D 		0.608 0.386
Sebox
M02097_2.00 		Mus musculus
NHTTAATTAN
NTAATTAADN		 PBM
Weirauch et al.(2014)
pTH6379 		0.605 0.421
ceh-5
M02179_2.00 		Caenorhabditis elegans
NNTAATDDN
NHHATTANN		 PBM
Weirauch et al.(2014)
pTH6562 		0.604 0.368
SHOX
M02095_2.00 		Homo sapiens
NTAATTRN
NYAATTAN		 PBM
Weirauch et al.(2014)
pTH5805 		0.601 0.404
Shox2
M00439_2.00 		Mus musculus
NTAATDDN
NHHATTAN		 PBM
Berger et al.(2008)
Shox2_2641 		0.601 0.404
SHOX
M03232_2.00 		Homo sapiens
NTAATTRN
NYAATTAN		 SELEX
Jolma et al.(2013)
SHOX_1 		0.601 0.404
SHOX2
M03204_2.00 		Homo sapiens
BTAATTRN
NYAATTAV		 SELEX
Jolma et al.(2013)
SHOX2_1 		0.601 0.404
Shox2
M03263_2.00 		Mus musculus
NTAATTRN
NYAATTAN		 SELEX
Jolma et al.(2013)
Shox2_1 		0.601 0.404
CG5369
M03876_2.00 		Drosophila melanogaster
TAATTHVATTA
TAATBDAATTA		 SELEX
Nitta et al.(2015)
CG5369_1 		0.601 0.404
CG5369
M03877_2.00 		Drosophila melanogaster
TAATTRNNTAATBN
NVATTANNYAATTA		 SELEX
Nitta et al.(2015)
CG5369_2 		0.601 0.404
CG5369
M03878_2.00 		Drosophila melanogaster
TAATTVRATWA
TWATYBAATTA		 SELEX
Nitta et al.(2015)
CG5369_3 		0.601 0.404
SHOX
M05366_2.00 		Homo sapiens
NTAATTRV
BYAATTAN		 SELEX
Yin et al.(2017)
SHOX_eDBD_HT-SELEX 		0.601 0.404
Shox2
M10772_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SHOX2_05 		0.601 0.404
SHOX
M05367_2.00 		Homo sapiens
NTAATTRV
BYAATTAN		 SELEX
Yin et al.(2017)
SHOX_eDBD_Methyl-HT-SELEX_1 		0.601 0.404
SHOX
M05368_2.00 		Homo sapiens
NTAAYGAN
NTCRTTAN		 SELEX
Yin et al.(2017)
SHOX_eDBD_Methyl-HT-SELEX_2 		0.601 0.404
C4B866_NEMVE
M02052_2.00 		Nematostella vectensis
NNTTAATTARNN
NNYTAATTAANN		 PBM
Weirauch et al.(2014)
pTH6176 		0.600 0.421
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSLAFP00000014889 Homeodomain 182 238

Links

Other Homeodomain family TFs
Other Loxodonta africana TFs

604 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
29805.m001471 Ricinus communis 29805.m001471 I 0.000
AMTR_s00052p00202630 Amborella trichopoda AMTR_s00052p00202630 I 0.000
Aquca_027_00077 Aquilegia coerulea Aquca_027_00077 I 0.000
S1FA2 Arabidopsis thaliana AT2G37120 I 0.000
S1FA3 Arabidopsis thaliana AT3G09735 D 0.000
S1FA1 Arabidopsis thaliana AT3G53370 I 0.000
BGIOSGA015142 Oryza indica BGIOSGA015142 N 0.000
BGIOSGA015145 Oryza indica BGIOSGA015145 N 0.000
Bo00703s130 Brassica oleracea Bo00703s130 I 0.000
Bo00703s150 Brassica oleracea Bo00703s150 I 0.000
Bo1g144300 Brassica oleracea Bo1g144300 I 0.000
Bo3g061880 Brassica oleracea Bo3g061880 I 0.000
Bo5g138130 Brassica oleracea Bo5g138130 I 0.000
Bo6g067310 Brassica oleracea Bo6g067310 I 0.000
Bostr.11793s0058 Boechera stricta Bostr.11793s0058 I 0.000
Bostr.22252s0094 Boechera stricta Bostr.22252s0094 I 0.000
Bostr.23794s0377 Boechera stricta Bostr.23794s0377 I 0.000
Bra003132 Brassica rapa Bra003132 I 0.000
Bra006994 Brassica rapa Bra006994 I 0.000
Bra029784 Brassica rapa Bra029784 I 0.000
Bra034084 Brassica rapa Bra034084 I 0.000
Bra039779 Brassica rapa Bra039779 I 0.000
Cagra.0612s0062 Capsella grandiflora Cagra.0612s0062 I 0.000
Cagra.0666s0032 Capsella grandiflora Cagra.0666s0032 I 0.000
Cagra.2515s0064 Capsella grandiflora Cagra.2515s0064 I 0.000
Carubv10018341m.g Capsella rubella Carubv10018341m.g I 0.000
Carubv10025429m.g Capsella rubella Carubv10025429m.g I 0.000
cassava45931.m1 Manihot esculenta cassava45931.m1 I 0.000
Ca_12027 Cicer arietinum Ca_12027 I 0.000
Ca_12028 Cicer arietinum Ca_12028 I 0.000
chr1.CM0033.550.nc Lotus japonicus chr1.CM0033.550.nc I 0.000
Ciclev10013218m.g Citrus clementina Ciclev10013218m.g I 0.000
Cla018106 Citrullus lanatus Cla018106 I 0.000
Cla018556 Citrullus lanatus Cla018556 I 0.000
Cucsa.124240 Cucumis sativus Cucsa.124240 I 0.000
Cucsa.307040 Cucumis sativus Cucsa.307040 I 0.000
estExt_fgenesh1_pg.C_340230 Physcomitrella patens estExt_fgenesh1_pg.C_340230 N 0.000
Eucgr.A01168 Eucalyptus grandis Eucgr.A01168 I 0.000
evm.TU.supercontig_638.2 Carica papaya evm.TU.supercontig_638.2 I 0.000
fgenesh1_pm.C_scaffold_5001425 Arabidopsis lyrata fgenesh1_pm.C_scaffold_5001425 I 0.000
fgenesh2_kg.3__997__AT3G09735.1 Arabidopsis lyrata fgenesh2_kg.3__997__AT3G09735.1 I 0.000
gene09647-v1.0-hybrid Fragaria vesca gene09647-v1.0-hybrid N 0.000
GLYMA03G33640 Glycine max GLYMA03G33640 I 0.000
GLYMA10G05790 Glycine max GLYMA10G05790 I 0.000
GLYMA13G20160 Glycine max GLYMA13G20160 I 0.000
GLYMA19G36350 Glycine max GLYMA19G36350 I 0.000
Gorai.002G249300 Gossypium raimondii Gorai.002G249300 I 0.000
Gorai.006G168100 Gossypium raimondii Gorai.006G168100 I 0.000
Gorai.009G419300 Gossypium raimondii Gorai.009G419300 I 0.000
GSMUA_Achr10G13120_001 Musa acuminata GSMUA_Achr10G13120_001 I 0.000
LPERR04G08410 Leersia perrieri LPERR04G08410 I 0.000
Lus10015073.g Linum usitatissimum Lus10015073.g I 0.000
Lus10023177.g Linum usitatissimum Lus10023177.g I 0.000
MDP0000559232 Malus domestica MDP0000559232 N 0.000
mgf000337m Mimulus guttatus mgf000337m I 0.000
mgf004062m Mimulus guttatus mgf004062m I 0.000
MTR_7g100880 Medicago truncatula MTR_7g100880 I 0.000
MTR_7g100890 Medicago truncatula MTR_7g100890 I 0.000
MTR_7g100905 Medicago truncatula MTR_7g100905 I 0.000
OB04G18770 Oryza brachyantha OB04G18770 I 0.000
OB04G18780 Oryza brachyantha OB04G18780 I 0.000
OBART04G11660 Oryza barthii OBART04G11660 N 0.000
OGLUM04G11340 Oryza glumaepatula OGLUM04G11340 N 0.000
OMERI04G10280 Oryza meridionalis OMERI04G10280 N 0.000
ONIVA04G09620 Oryza nivara ONIVA04G09620 N 0.000
OPUNC04G09660 Oryza punctata OPUNC04G09660 N 0.000
orange1.1g044991m.g Citrus sinensis orange1.1g044991m.g I 0.000
ORGLA04G0086800 Oryza glaberrima ORGLA04G0086800 N 0.000
ORUFI04G12850 Oryza rufipogon ORUFI04G12850 N 0.000
OS04G0408900 Oryza sativa OS04G0408900 N 0.000
PGSC0003DMG400001772 Solanum tuberosum PGSC0003DMG400001772 I 0.000
PGSC0003DMG400020934 Solanum tuberosum PGSC0003DMG400020934 I 0.000
PGSC0003DMG401017590 Solanum tuberosum PGSC0003DMG401017590 I 0.000
PK08477.1 Cannabis sativa PK08477.1 I 0.000
POPTR_0006s13230 Populus trichocarpa POPTR_0006s13230 I 0.000
POPTR_0016s08890 Populus trichocarpa POPTR_0016s08890 I 0.000
SapurV1A.0112s0080 Salix purpurea SapurV1A.0112s0080 I 0.000
SapurV1A.0209s0130 Salix purpurea SapurV1A.0209s0130 I 0.000
scaffold_402348.1 Arabidopsis lyrata scaffold_402348.1 I 0.000
Solyc09g007500.2 Solanum lycopersicum Solyc09g007500.2 I 0.000
TCM_022113 Theobroma cacao TCM_022113 I 0.000
Thhalv10010878m.g Eutrema salsugineum Thhalv10010878m.g I 0.000
Thhalv10017496m.g Eutrema salsugineum Thhalv10017496m.g I 0.000
Thhalv10021874m.g Eutrema salsugineum Thhalv10021874m.g I 0.000
VIT_06s0004g03160 Vitis vinifera VIT_06s0004g03160 I 0.000
VIT_08s0040g02220 Vitis vinifera VIT_08s0040g02220 I 0.000