nhr-44 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003634 T306158_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in head muscle; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.854 0.514
nhr-182
M00701_2.00 		Caenorhabditis elegans
DWBYGTGWCH
DGWCACRVWH		 PBM
Narasimhan et al.(2015)
pTH10779 		0.853 0.529
nhr-182
M00702_2.00 		Caenorhabditis elegans
NNNHRTRNHN
NDNYAYDNNN		 PBM
Narasimhan et al.(2015)
pTH6106 		0.853 0.529
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
T19A5.4 Nuclear receptor 22 93

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

31 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE14847 Caenorhabditis remanei CRE14847 I 0.991
CBG19141 Caenorhabditis briggsae CBG19141 I 0.989
CRE14848 Caenorhabditis remanei CRE14848 I 0.987
CJA03572 Caenorhabditis japonica CJA03572 I 0.986
CRE01447 Caenorhabditis remanei CRE01447 N 0.979
CBG06387 Caenorhabditis briggsae CBG06387 I 0.902
CRE14845 Caenorhabditis remanei CRE14845 I 0.899
nhr-110 Caenorhabditis elegans WBGene00003700 I 0.898
CBG19144 Caenorhabditis briggsae CBG19144 I 0.893
nhr-130 Caenorhabditis elegans WBGene00003720 I 0.880
nhr-195 Caenorhabditis elegans WBGene00019115 N 0.864
nhr-232 Caenorhabditis elegans WBGene00012494 D 0.854
nhr-182 Caenorhabditis elegans WBGene00018265 D 0.853
CJA19466 Caenorhabditis japonica CJA19466 I 0.850
CRE05778 Caenorhabditis remanei CRE05778 I 0.844
CRE30948 Caenorhabditis remanei CRE30948 I 0.841
CBG09567 Caenorhabditis briggsae CBG09567 I 0.836
nhr-117 Caenorhabditis elegans WBGene00003707 I 0.811
NBR_0001218401 Nippostrongylus brasiliensis NBR_0001218401 I 0.799
ANCCEY_13226 Ancylostoma ceylanicum ANCCEY_13226 I 0.799
HCOI00483700 Haemonchus contortus HCOI00483700 I 0.799
HPLM_0000277901 Haemonchus placei HPLM_0000277901 I 0.799
CBN00299 Caenorhabditis brenneri CBN00299 I 0.788
scaffold31-EXSNAP2012.20 Pristionchus exspectatus scaffold31-EXSNAP2012.20 I 0.786
SVUK_0002058501 Strongylus vulgaris SVUK_0002058501 I 0.784
nhr-179 Caenorhabditis elegans WBGene00017512 I 0.782
CRE08749 Caenorhabditis remanei CRE08749 I 0.776
CBG04928 Caenorhabditis briggsae CBG04928 I 0.770
CRE16082 Caenorhabditis remanei CRE16082 I 0.752
PEQ_0000560101 Parascaris equorum PEQ_0000560101 I 0.752
nhr-201 Caenorhabditis elegans WBGene00019741 I 0.749