nhr-182 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00018265 T306343_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-182
M00701_2.00		 Caenorhabditis elegans
DWBYGTGWCH
DGWCACRVWH		 PBM
Narasimhan et al.(2015)
pTH10779		 (Direct) (Direct)
nhr-182
M00702_2.00		 Caenorhabditis elegans
NNNHRTRNHN
NDNYAYDNNN		 PBM
Narasimhan et al.(2015)
pTH6106		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CBG01250
M02391_2.00 		Caenorhabditis briggsae
WBYGTGTC
GACACRVW		 PBM
Weirauch et al.(2014)
pTH6110 		0.851 0.571
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.812 0.514
For this family, TFs with SR scores > 0.745 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00701_2.00 Nuclear receptor 4 76
M00702_2.00 Nuclear receptor 1 73

DNA Binding Domains

Protein ID Domain From To Sequence
F41B5.9 Nuclear receptor 4 76

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

55 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG01235 Caenorhabditis briggsae CBG01235 I 0.966
CBN15241 Caenorhabditis brenneri CBN15241 I 0.966
CRE08751 Caenorhabditis remanei CRE08751 I 0.966
CJA19466 Caenorhabditis japonica CJA19466 I 0.955
nhr-183 Caenorhabditis elegans WBGene00018266 I 0.949
CBG06387 Caenorhabditis briggsae CBG06387 I 0.945
CRE08753 Caenorhabditis remanei CRE08753 I 0.939
nhr-130 Caenorhabditis elegans WBGene00003720 I 0.931
CRE08754 Caenorhabditis remanei CRE08754 I 0.922
nhr-190 Caenorhabditis elegans WBGene00018622 I 0.919
nhr-133 Caenorhabditis elegans WBGene00003723 I 0.902
WBGene00003673 Caenorhabditis elegans WBGene00003673 I 0.901
nhr-212 Caenorhabditis elegans WBGene00020153 I 0.886
CRE08755 Caenorhabditis remanei CRE08755 I 0.882
CRE08749 Caenorhabditis remanei CRE08749 I 0.880
CRE18698 Caenorhabditis remanei CRE18698 I 0.880
nhr-123 Caenorhabditis elegans WBGene00003713 I 0.868
nhr-184 Caenorhabditis elegans WBGene00018415 I 0.859
CRE18699 Caenorhabditis remanei CRE18699 I 0.859
CBN00299 Caenorhabditis brenneri CBN00299 I 0.857
CBG19141 Caenorhabditis briggsae CBG19141 I 0.854
CRE14845 Caenorhabditis remanei CRE14845 I 0.853
nhr-44 Caenorhabditis elegans WBGene00003634 I 0.853
CRE05778 Caenorhabditis remanei CRE05778 I 0.851
CBG01250 Caenorhabditis briggsae CBG01250 D 0.851
nhr-98 Caenorhabditis elegans WBGene00003688 I 0.849
CBG01353 Caenorhabditis briggsae CBG01353 I 0.841
nhr-202 Caenorhabditis elegans WBGene00019742 I 0.832
nhr-99 Caenorhabditis elegans WBGene00003689 I 0.830
CBN03087 Caenorhabditis brenneri CBN03087 I 0.828
CRE14847 Caenorhabditis remanei CRE14847 I 0.827
CRE30948 Caenorhabditis remanei CRE30948 I 0.825
nhr-201 Caenorhabditis elegans WBGene00019741 I 0.823
CBG17906 Caenorhabditis briggsae CBG17906 I 0.816
nhr-232 Caenorhabditis elegans WBGene00012494 D 0.812
CBG01243 Caenorhabditis briggsae CBG01243 I 0.809
CBG17898 Caenorhabditis briggsae CBG17898 I 0.807
CBG19144 Caenorhabditis briggsae CBG19144 I 0.805
nhr-179 Caenorhabditis elegans WBGene00017512 I 0.803
ANCCEY_07914 Ancylostoma ceylanicum ANCCEY_07914 I 0.799
PEQ_0000560101 Parascaris equorum PEQ_0000560101 I 0.795
CBG09567 Caenorhabditis briggsae CBG09567 I 0.789
CBG27350 Caenorhabditis briggsae CBG27350 I 0.784
CBG01251 Caenorhabditis briggsae CBG01251 I 0.775
CJA16882 Caenorhabditis japonica CJA16882 I 0.774
CRE08762 Caenorhabditis remanei CRE08762 I 0.771
CRE05044 Caenorhabditis remanei CRE05044 I 0.769
CRE19033 Caenorhabditis remanei CRE19033 I 0.768
CBG01352 Caenorhabditis briggsae CBG01352 I 0.768
CJA03572 Caenorhabditis japonica CJA03572 I 0.766
CRE14848 Caenorhabditis remanei CRE14848 I 0.761
CBG15881 Caenorhabditis briggsae CBG15881 I 0.756
CBN18082 Caenorhabditis brenneri CBN18082 I 0.755
scaffold31-EXSNAP2012.20 Pristionchus exspectatus scaffold31-EXSNAP2012.20 I 0.753
nhr-59 Caenorhabditis elegans WBGene00003649 I 0.747