nhr-130 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003720 T306242_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-182
M00701_2.00 		Caenorhabditis elegans
DWBYGTGWCH
DGWCACRVWH		 PBM
Narasimhan et al.(2015)
pTH10779 		0.931 0.571
nhr-182
M00702_2.00 		Caenorhabditis elegans
NNNHRTRNHN
NDNYAYDNNN		 PBM
Narasimhan et al.(2015)
pTH6106 		0.931 0.571
CBG01250
M02391_2.00 		Caenorhabditis briggsae
WBYGTGTC
GACACRVW		 PBM
Weirauch et al.(2014)
pTH6110 		0.855 0.529
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.816 0.486
nhr-84
M02414_2.00 		Caenorhabditis elegans
NRGTCACAAN
NTTGTGACYN		 PBM
Weirauch et al.(2014)
pTH5828 		0.746 0.571
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
T01G6.8 Nuclear receptor 35 105

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

69 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG06387 Caenorhabditis briggsae CBG06387 I 0.988
CJA19466 Caenorhabditis japonica CJA19466 I 0.972
CRE08755 Caenorhabditis remanei CRE08755 I 0.945
nhr-182 Caenorhabditis elegans WBGene00018265 D 0.931
CRE08754 Caenorhabditis remanei CRE08754 I 0.925
nhr-184 Caenorhabditis elegans WBGene00018415 I 0.911
nhr-212 Caenorhabditis elegans WBGene00020153 I 0.908
CBG19141 Caenorhabditis briggsae CBG19141 I 0.894
CRE18698 Caenorhabditis remanei CRE18698 I 0.891
nhr-44 Caenorhabditis elegans WBGene00003634 I 0.880
nhr-133 Caenorhabditis elegans WBGene00003723 I 0.878
CRE18699 Caenorhabditis remanei CRE18699 I 0.869
CRE14847 Caenorhabditis remanei CRE14847 I 0.866
CJA03572 Caenorhabditis japonica CJA03572 I 0.861
CBG27350 Caenorhabditis briggsae CBG27350 I 0.859
CBN00299 Caenorhabditis brenneri CBN00299 I 0.856
CBG01250 Caenorhabditis briggsae CBG01250 D 0.855
CRE14845 Caenorhabditis remanei CRE14845 I 0.848
WBGene00003673 Caenorhabditis elegans WBGene00003673 I 0.848
CRE08753 Caenorhabditis remanei CRE08753 I 0.847
CRE05044 Caenorhabditis remanei CRE05044 I 0.843
nhr-190 Caenorhabditis elegans WBGene00018622 I 0.838
CBG09567 Caenorhabditis briggsae CBG09567 I 0.835
CBG17906 Caenorhabditis briggsae CBG17906 I 0.828
NBR_0001218401 Nippostrongylus brasiliensis NBR_0001218401 I 0.828
HCOI00483700 Haemonchus contortus HCOI00483700 I 0.825
HPLM_0000277901 Haemonchus placei HPLM_0000277901 I 0.825
ANCCEY_13226 Ancylostoma ceylanicum ANCCEY_13226 I 0.825
CRE14848 Caenorhabditis remanei CRE14848 I 0.825
CRE08749 Caenorhabditis remanei CRE08749 I 0.825
CBG15881 Caenorhabditis briggsae CBG15881 I 0.823
CBG01251 Caenorhabditis briggsae CBG01251 I 0.822
SVUK_0002058501 Strongylus vulgaris SVUK_0002058501 I 0.822
nhr-232 Caenorhabditis elegans WBGene00012494 D 0.816
scaffold31-EXSNAP2012.20 Pristionchus exspectatus scaffold31-EXSNAP2012.20 I 0.815
CBN03087 Caenorhabditis brenneri CBN03087 I 0.811
nhr-183 Caenorhabditis elegans WBGene00018266 I 0.809
CRE11350 Caenorhabditis remanei CRE11350 N 0.806
nhr-110 Caenorhabditis elegans WBGene00003700 I 0.806
CRE08760 Caenorhabditis remanei CRE08760 I 0.805
ANCCEY_07914 Ancylostoma ceylanicum ANCCEY_07914 I 0.803
nhr-179 Caenorhabditis elegans WBGene00017512 I 0.802
CRE30948 Caenorhabditis remanei CRE30948 I 0.801
CBG01235 Caenorhabditis briggsae CBG01235 I 0.799
CBN15241 Caenorhabditis brenneri CBN15241 I 0.799
CRE08751 Caenorhabditis remanei CRE08751 I 0.799
nhr-202 Caenorhabditis elegans WBGene00019742 I 0.797
CBG01352 Caenorhabditis briggsae CBG01352 I 0.797
CBG01353 Caenorhabditis briggsae CBG01353 I 0.795
PEQ_0000560101 Parascaris equorum PEQ_0000560101 I 0.791
CBG06609 Caenorhabditis briggsae CBG06609 I 0.788
CBG06599 Caenorhabditis briggsae CBG06599 I 0.788
CRE05778 Caenorhabditis remanei CRE05778 I 0.788
HPLM_0000974301 Haemonchus placei HPLM_0000974301 I 0.786
HCOI01190000 Haemonchus contortus HCOI01190000 I 0.786
CBG17898 Caenorhabditis briggsae CBG17898 I 0.781
CBG19144 Caenorhabditis briggsae CBG19144 I 0.780
nhr-201 Caenorhabditis elegans WBGene00019741 I 0.778
CJA28065 Caenorhabditis japonica CJA28065 I 0.772
L596_g14586 Steinernema carpocapsae L596_g14586 I 0.764
CBG01234 Caenorhabditis briggsae CBG01234 N 0.762
nhr-178 Caenorhabditis elegans WBGene00017510 I 0.756
nhr-123 Caenorhabditis elegans WBGene00003713 I 0.754
ASU_09680 Ascaris suum ASU_09680 N 0.752
CRE08762 Caenorhabditis remanei CRE08762 I 0.751
nhr-99 Caenorhabditis elegans WBGene00003689 I 0.751
nhr-84 Caenorhabditis elegans WBGene00003674 D 0.746
nhr-117 Caenorhabditis elegans WBGene00003707 I 0.746
nhr-213 Caenorhabditis elegans WBGene00011520 I 0.745