ENSMEUG00000001823 (Macropus eugenii)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSMEUG00000001823 T324702_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.980 0.980
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.980 0.980
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.980 0.980
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.980 0.980
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.980 0.980
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.980 0.980
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.980 0.980
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.941 0.941
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.941 0.941
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMEUP00000001667 SMAD 36 136

Links

Other SMAD family TFs
Other Macropus eugenii TFs

212 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SMAD4 Pteropus vampyrus ENSPVAG00000004261 I 1.000
SMAD4 Microcebus murinus ENSMICG00000017525 I 1.000
SMAD4 Homo sapiens ENSG00000141646 D 0.988
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.980
SMAD4 Equus caballus ENSECAG00000017857 I 0.971
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.971
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.971
SMAD4 Felis catus ENSFCAG00000005257 I 0.971
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.971
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.971
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.971
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.971
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.971
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.971
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.971
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.971
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.971
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.971
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.971
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.971
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.971
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.971
Smad4 Mus musculus ENSMUSG00000024515 D 0.971
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.971
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.971
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.971
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.971
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.971
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.971
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.971
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.971
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.971
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.971
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.971
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.971
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.971
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.971
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.971
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.971
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.971
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.971
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.971
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.971
AAH84196 Xenopus laevis AAH84196 I 0.971
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.971
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.971
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.971
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.971
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.971
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.971
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.971
SMAD4 Bos taurus ENSBTAG00000006919 I 0.971
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.971
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.971
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.971
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.971
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.961
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.961
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.961
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.961
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.961
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.961
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.961
smad4a Oryzias latipes ENSORLG00000005020 I 0.961
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.961
smad4a Danio rerio ENSDARG00000075226 I 0.961
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.951
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.951
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.951
SMAD4 Danio rerio ENSDARG00000012649 I 0.951
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.951
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.951
ISCW018468 Ixodes scapularis ISCW018468 I 0.951
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.951
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.951
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.951
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.951
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.951
PHUM002670 Pediculus humanus PHUM002670 I 0.941
SMAR013850 Strigamia maritima SMAR013850 I 0.941
MDOA012885 Musca domestica MDOA012885 I 0.941
LCUP007928 Lucilia cuprina LCUP007928 I 0.941
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.941
TC010848 Tribolium castaneum TC010848 I 0.941
GE10952 Drosophila yakuba FBgn0228782 I 0.941
GJ23092 Drosophila virilis FBgn0210194 I 0.941
GM16436 Drosophila sechellia FBgn0171351 I 0.941
GL23637 Drosophila persimilis FBgn0161227 I 0.941
GH18642 Drosophila grimshawi FBgn0126109 I 0.941
GK11724 Drosophila willistoni FBgn0213735 I 0.941
GF22974 Drosophila ananassae FBgn0099968 I 0.941
GG11819 Drosophila erecta FBgn0104114 I 0.941
Med Drosophila melanogaster FBgn0011655 D 0.941
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.941
L798_13939 Zootermopsis nevadensis L798_13939 I 0.941
GI23400 Drosophila mojavensis FBgn0146126 I 0.941
AAEL013896 Aedes aegypti AAEL013896 I 0.941
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.931
GB50071 Apis mellifera GB50071 I 0.931
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.931
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.931
NV12984 Nasonia vitripennis NV12984 I 0.931
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.931
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.931
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.931
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.931
SINV15516 Solenopsis invicta SINV15516 I 0.931
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.931
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.931
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.931
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.931
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.931
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.931
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.931
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.931
AFUN009864 Anopheles funestus AFUN009864 I 0.922
AEPI002385 Anopheles epiroticus AEPI002385 I 0.922
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.922
ADIR002761 Anopheles dirus ADIR002761 I 0.922
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.922
AFAF011208 Anopheles farauti AFAF011208 I 0.922
AGAP002902 Anopheles gambiae AGAP002902 I 0.922
CLEC002594 Cimex lectularius CLEC002594 I 0.922
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.922
AARA004719 Anopheles arabiensis AARA004719 I 0.922
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.922
AATE010695 Anopheles atroparvus AATE010695 I 0.922
ACHR000067 Anopheles christyi ACHR000067 I 0.922
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.922
ACOM037505 Anopheles coluzzii ACOM037505 I 0.922
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.922
ACUA025512 Anopheles culicifacies ACUA025512 I 0.922
AMAM019778 Anopheles maculatus AMAM019778 I 0.922
KGM_12572 Danaus plexippus KGM_12572 I 0.922
MCINX014520 Melitaea cinxia MCINX014520 I 0.922
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.922
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.922
HMEL002203 Heliconius melpomene HMEL002203 I 0.922
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.922
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.922
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.922
AMIN000723 Anopheles minimus AMIN000723 I 0.922
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.922
AMEM015931 Anopheles merus AMEM015931 I 0.922
RPRC010188 Rhodnius prolixus RPRC010188 I 0.922
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.921
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.921
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.912
LotgiG131078 Lottia gigantea LotgiG131078 I 0.912
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.912
CapteG179368 Capitella teleta CapteG179368 I 0.911
ADAC007516 Anopheles darlingi ADAC007516 I 0.911
AALB009485 Anopheles albimanus AALB009485 I 0.911
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.902
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.902
smad4 Ciona intestinalis ENSCING00000005559 I 0.901
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.892
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.882
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.882
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.882
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.873
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.873
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.873
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.873
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.873
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.863
CGI_10018464 Crassostrea gigas CGI_10018464 I 0.857
HelroG88197 Helobdella robusta HelroG88197 I 0.853
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.853
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.853
Aan_R014474 Calypte anna Aan_R014474 I 0.845
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.833
ML02191a Mnemiopsis leidyi ML02191a I 0.833
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.833
ACEP19585 Atta cephalotes ACEP19585 I 0.822
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.821
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.804
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.804
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.794
D917_09719 Trichinella nativa D917_09719 I 0.794
EFV62078 Trichinella spiralis EFV62078 I 0.794
T265_11013 Opisthorchis viverrini T265_11013 I 0.784
D915_03789 Fasciola hepatica D915_03789 I 0.784
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.782
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.775
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.775
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.765
D918_00298 Trichuris suis D918_00298 I 0.760
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.755
Bm3575 Brugia malayi Bm3575 I 0.755
HelroG76435 Helobdella robusta HelroG76435 I 0.755
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.755
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.755
ASU_13433 Ascaris suum ASU_13433 I 0.752
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.752
Sakowv30001112m.g Saccoglossus kowalevskii Sakowv30001112m.g I 0.746
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.745
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.745
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.745
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.745
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.743
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.735
LOAG_08923 Loa loa LOAG_08923 I 0.735
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.735
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.735
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.735
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.733
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.725
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.706
Smp_033950 Schistosoma mansoni Smp_033950 I 0.706
HmN_000727600 Hymenolepis microstoma HmN_000727600 N 0.703
HNAJ_0000282001 Hymenolepis nana HNAJ_0000282001 N 0.703