Six6 (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000021099 T212416_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six6
M00169_2.00		 Mus musculus
NNAYMNN
NNKRTNN		 PBM
Badis et al.(2009)
Six6_2267		 (Direct) (Direct)
Six6
M00412_2.00		 Mus musculus
NNNTGATAYCN
NGRTATCANNN		 PBM
Berger et al.(2008)
Six6_2267		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SIX6
M00326_2.00 		Homo sapiens
NNDATMB
VKATHNN		 PBM
Barrera et al.(2016)
SIX6_REF 		0.867 1.000
SIX6
M05357_2.00 		Homo sapiens
NNYGATASVB
VBSTATCRNN		 SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX 		0.867 1.000
SIX6
M05358_2.00 		Homo sapiens
VBVYAYCRNN
NNYGRTRBVB		 SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX 		0.867 1.000
Six3
M00483_2.00 		Mus musculus
NNNAYMN
NKRTNNN		 PBM
Berger et al.(2008)
Six3_1732 		0.865 0.982
SIX3
M05159_2.00 		Homo sapiens
NNYGATABBN
NVVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX 		0.865 0.982
SIX3
M10698_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX3_Q6 		0.865 0.982
SIX6
M00325_2.00 		Homo sapiens
NNNDATMB
VKATHNNN		 PBM
Barrera et al.(2016)
SIX6_H141N 		0.865 0.982
SIX3
M05160_2.00 		Homo sapiens
NNYGATABVB
VBVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX 		0.865 0.982
six3
M02102_2.00 		Oryzias latipes
NNDAYMBNNN
NNNVKRTHNN		 PBM
Weirauch et al.(2014)
pTH5928 		0.865 0.947
Optix
M02124_2.00 		Drosophila melanogaster
NNNNNDATMN
NKATHNNNNN		 PBM
Weirauch et al.(2014)
pTH5437 		0.865 0.930
Optix
M03850_2.00 		Drosophila melanogaster
TAATYTAATTA
TAATTARATTA		 SELEX
Nitta et al.(2015)
Optix_1 		0.865 0.930
Optix
M06526_2.00 		Drosophila melanogaster
TGATA
TATCA		 B1H
Mathelier et al.(2014)
MA0199.1 		0.865 0.930
Optix
M06327_2.00 		Drosophila melanogaster
HHVTGATA
TATCABDD		 B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360 		0.865 0.930
Optix
M06328_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360 		0.865 0.930
SIX6
M00327_2.00 		Homo sapiens
NHDAYMBNN
NNVKRTHDN		 PBM
Barrera et al.(2016)
SIX6_T165A 		0.860 0.982
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00169_2.00 Homeodomain 16 72
M00412_2.00 Homeodomain 16 72

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000021519 Homeodomain 129 185

Links

Other Homeodomain family TFs
Other Mus musculus TFs

296 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
EIL1 Arabidopsis thaliana AT2G27050 D
EIN3 Arabidopsis thaliana AT3G20770 D
Q9ZWK1_TOBAC Nicotiana tabacum Q9ZWK1_TOBAC D
e_gw1.87.73.1 Physcomitrella patens e_gw1.87.73.1 D
AMTR_s00119p00117410 Amborella trichopoda AMTR_s00119p00117410 I
BGIOSGA012535 Oryza indica BGIOSGA012535 I
BGIOSGA023694 Oryza indica BGIOSGA023694 I
Bo1g108650 Brassica oleracea Bo1g108650 I
Bo3g041690 Brassica oleracea Bo3g041690 I
Bo3g076180 Brassica oleracea Bo3g076180 I
Bo5g106280 Brassica oleracea Bo5g106280 I
Bra000528 Brassica rapa Bra000528 I
Bra001802 Brassica rapa Bra001802 I
BRADI1G63780 Brachypodium distachyon BRADI1G63780 I
F775_28545 Aegilops tauschii F775_28545 I
EIN3 Arabidopsis lyrata fgenesh2_kg.3__2304__AT3G20770.1 I
EIL1 Arabidopsis lyrata fgenesh2_kg.4__646__AT2G27050.1 I
GLYMA02G44220 Glycine max GLYMA02G44220 I
GLYMA13G03660 Glycine max GLYMA13G03660 I
GLYMA13G03700 Glycine max GLYMA13G03700 I
GLYMA13G41751 Glycine max GLYMA13G41751 I
GLYMA14G04550 Glycine max GLYMA14G04550 I
GLYMA15G03650 Glycine max GLYMA15G03650 I
GLYMA20G12250 Glycine max GLYMA20G12250 I
GRMZM2G003558 Zea mays GRMZM2G003558 I
GRMZM2G033570 Zea mays GRMZM2G033570 I
GRMZM2G151811 Zea mays GRMZM2G151811 I
GRMZM2G317584 Zea mays GRMZM2G317584 I
GSMUA_Achr10G12800_001 Musa acuminata GSMUA_Achr10G12800_001 I
GSMUA_Achr11G25120_001 Musa acuminata GSMUA_Achr11G25120_001 I
GSMUA_Achr2G11540_001 Musa acuminata GSMUA_Achr2G11540_001 I
GSMUA_Achr3G09440_001 Musa acuminata GSMUA_Achr3G09440_001 I
GSMUA_Achr5G27670_001 Musa acuminata GSMUA_Achr5G27670_001 I
GSMUA_Achr6G15930_001 Musa acuminata GSMUA_Achr6G15930_001 I
GSMUA_Achr9G17080_001 Musa acuminata GSMUA_Achr9G17080_001 I
LPERR03G13760 Leersia perrieri LPERR03G13760 I
LPERR07G23570 Leersia perrieri LPERR07G23570 I
MLOC_14619 Hordeum vulgare MLOC_14619 I
MTR_2g098470 Medicago truncatula MTR_2g098470 I
MTR_3g078770 Medicago truncatula MTR_3g078770 I
MTR_5g087790 Medicago truncatula MTR_5g087790 I
OB07G32250 Oryza brachyantha OB07G32250 I
OBART07G26760 Oryza barthii OBART07G26760 I
OGLUM03G15860 Oryza glumaepatula OGLUM03G15860 I
OLONG_004360 Oryza longistaminata OLONG_004360 I
OMERI03G14140 Oryza meridionalis OMERI03G14140 I
OMERI05G02190 Oryza meridionalis OMERI05G02190 I
OMERI07G23380 Oryza meridionalis OMERI07G23380 I
ONIVA03G16680 Oryza nivara ONIVA03G16680 I
ONIVA07G26490 Oryza nivara ONIVA07G26490 I
OPUNC03G15240 Oryza punctata OPUNC03G15240 I
OPUNC07G25150 Oryza punctata OPUNC07G25150 I
ORGLA03G0150600 Oryza glaberrima ORGLA03G0150600 I
ORGLA07G0211700 Oryza glaberrima ORGLA07G0211700 I
ORUFI03G16290 Oryza rufipogon ORUFI03G16290 I
ORUFI07G27710 Oryza rufipogon ORUFI07G27710 I
OS03G0324200 Oryza sativa OS03G0324200 I
OS03G0324300 Oryza sativa OS03G0324300 I
OS07G0685700 Oryza sativa OS07G0685700 I
PGSC0003DMG400005914 Solanum tuberosum PGSC0003DMG400005914 I
PGSC0003DMG400005915 Solanum tuberosum PGSC0003DMG400005915 I
PGSC0003DMG400008712 Solanum tuberosum PGSC0003DMG400008712 I
PGSC0003DMG400027507 Solanum tuberosum PGSC0003DMG400027507 I
POPTR_0001s05360 Populus trichocarpa POPTR_0001s05360 I
POPTR_0004s20830 Populus trichocarpa POPTR_0004s20830 I
POPTR_0008s01200 Populus trichocarpa POPTR_0008s01200 I
POPTR_0009s16080 Populus trichocarpa POPTR_0009s16080 I
POPTR_0010s25370 Populus trichocarpa POPTR_0010s25370 I
PRUPE_ppa003493mg Prunus persica PRUPE_ppa003493mg I
PRUPE_ppa003550mg Prunus persica PRUPE_ppa003550mg I
Sb01g036740 Sorghum bicolor Sb01g036740 I
Sb02g043350 Sorghum bicolor Sb02g043350 I
SELMODRAFT_112063 Selaginella moellendorffii SELMODRAFT_112063 I
SELMODRAFT_136229 Selaginella moellendorffii SELMODRAFT_136229 I
SELMODRAFT_449238 Selaginella moellendorffii SELMODRAFT_449238 I
Si029213m.g Setaria italica Si029213m.g I
Si034616m.g Setaria italica Si034616m.g I
Solyc01g009170.2 Solanum lycopersicum Solyc01g009170.2 I
Solyc01g096810.2 Solanum lycopersicum Solyc01g096810.2 I
Solyc06g073720.1 Solanum lycopersicum Solyc06g073720.1 I
Solyc06g073730.1 Solanum lycopersicum Solyc06g073730.1 I
TCM_042022 Theobroma cacao TCM_042022 I
Traes_2BS_647C82888 Triticum aestivum Traes_2BS_647C82888 I
Traes_4AS_2BDA1260C Triticum aestivum Traes_4AS_2BDA1260C I
Traes_4BL_F34EBD618 Triticum aestivum Traes_4BL_F34EBD618 I
Traes_4DL_C083C804E Triticum aestivum Traes_4DL_C083C804E I
Traes_5DL_62DEF8361 Triticum aestivum Traes_5DL_62DEF8361 I
TRIUR3_30860 Triticum urartu TRIUR3_30860 I
VIT_06s0009g01380 Vitis vinifera VIT_06s0009g01380 I
VIT_13s0047g00250 Vitis vinifera VIT_13s0047g00250 I
Ca_07534 Cicer arietinum Ca_07534 I
Ca_10236 Cicer arietinum Ca_10236 I
Pm017009 Prunus mume Pm017009 I
29708.m000185 Ricinus communis 29708.m000185 I
cassava3620.m1 Manihot esculenta cassava3620.m1 I
Cucsa.142750 Cucumis sativus Cucsa.142750 I
Cucsa.364340 Cucumis sativus Cucsa.364340 I
e_gw1.11.194.1 Physcomitrella patens e_gw1.11.194.1 I
mgf012394m Mimulus guttatus mgf012394m I
mgf015996m Mimulus guttatus mgf015996m I
mgf018950m Mimulus guttatus mgf018950m I
Aquca_014_00938 Aquilegia coerulea Aquca_014_00938 I
Bostr.19424s0573 Boechera stricta Bostr.19424s0573 I
Bostr.29505s0037 Boechera stricta Bostr.29505s0037 I
Cagra.2243s0007 Capsella grandiflora Cagra.2243s0007 I
Cagra.6016s0001 Capsella grandiflora Cagra.6016s0001 I
Carubv10013213m.g Capsella rubella Carubv10013213m.g I
Carubv10022879m.g Capsella rubella Carubv10022879m.g I
Ciclev10000608m.g Citrus clementina Ciclev10000608m.g I
Ciclev10000617m.g Citrus clementina Ciclev10000617m.g I
Ciclev10014617m.g Citrus clementina Ciclev10014617m.g I
Eucgr.G02632 Eucalyptus grandis Eucgr.G02632 I
Eucgr.J00631 Eucalyptus grandis Eucgr.J00631 I
evm.TU.supercontig_103.60 Carica papaya evm.TU.supercontig_103.60 I
evm.TU.supercontig_54.30 Carica papaya evm.TU.supercontig_54.30 I
gene00379-v1.0-hybrid Fragaria vesca gene00379-v1.0-hybrid I
gene25474-v1.0-hybrid Fragaria vesca gene25474-v1.0-hybrid I
Gorai.003G140600 Gossypium raimondii Gorai.003G140600 I
Gorai.004G227800 Gossypium raimondii Gorai.004G227800 I
Gorai.009G105400 Gossypium raimondii Gorai.009G105400 I
Gorai.013G266300 Gossypium raimondii Gorai.013G266300 I
MDP0000202831 Malus domestica MDP0000202831 I
MDP0000212881 Malus domestica MDP0000212881 I
MDP0000306498 Malus domestica MDP0000306498 I
MDP0000564884 Malus domestica MDP0000564884 I
orange1.1g007017m.g Citrus sinensis orange1.1g007017m.g I
orange1.1g007174m.g Citrus sinensis orange1.1g007174m.g I
orange1.1g009144m.g Citrus sinensis orange1.1g009144m.g I
Pavir.Bb03705 Panicum virgatum Pavir.Bb03705 I
Pavir.Ia03450 Panicum virgatum Pavir.Ia03450 I
Pavir.Ib01512 Panicum virgatum Pavir.Ib01512 I
Pavir.J01001 Panicum virgatum Pavir.J01001 I
SapurV1A.0036s0870 Salix purpurea SapurV1A.0036s0870 I
SapurV1A.0070s0670 Salix purpurea SapurV1A.0070s0670 I
SapurV1A.0561s0140 Salix purpurea SapurV1A.0561s0140 I
SapurV1A.0615s0150 Salix purpurea SapurV1A.0615s0150 I
Thhalv10001938m.g Eutrema salsugineum Thhalv10001938m.g I
Thhalv10020292m.g Eutrema salsugineum Thhalv10020292m.g I
PK01239.1 Cannabis sativa PK01239.1 I
PK13351.1 Cannabis sativa PK13351.1 I
chr2.CM0031.190.nc Lotus japonicus chr2.CM0031.190.nc I
chr3.LjB09K03.50.nc Lotus japonicus chr3.LjB09K03.50.nc I
PDK_20s1443543g001 Phoenix dactylifera PDK_20s1443543g001 I
TRIUR3_26675 Triticum urartu TRIUR3_26675 N