PAX4 (Sorex araneus)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSSARG00000004842 T237486_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX4
M00350_2.00 		Homo sapiens
NNNATTAN
NTAATNNN		 PBM
Barrera et al.(2016)
PAX4_REF 		0.889 0.889
PAX4
M00351_2.00 		Homo sapiens
NNNATTAN
NTAATNNN		 PBM
Barrera et al.(2016)
PAX4_REF_R3 		0.889 0.889
Pax4
M00542_2.00 		Mus musculus
NNNATTAN
NTAATNNN		 PBM
Berger et al.(2008)
Pax4_3989 		0.889 0.889
PAX4
M03295_2.00 		Homo sapiens
HKAATTAR
YTAATTMD		 SELEX
Jolma et al.(2013)
PAX4_1 		0.889 0.889
PAX4
M03296_2.00 		Homo sapiens
YKAATTAV
BTAATTMR		 SELEX
Jolma et al.(2013)
PAX4_2 		0.889 0.889
PAX4
M03883_2.00 		Homo sapiens
SGTCACGCWTSRNTG
CANYSAWGCGTGACS		 SELEX
Nitta et al.(2015)
PAX4_1 		0.889 0.889
PAX4
M03884_2.00 		Homo sapiens
NNAATTANYKAATDMV
BKHATTMRNTAATTNN		 SELEX
Nitta et al.(2015)
PAX4_2 		0.889 0.889
PAX4
M05430_2.00 		Homo sapiens
NAATTANNNNNNVNTAATTN
NAATTANBNNNNNNTAATTN		 SELEX
Yin et al.(2017)
PAX4_eDBD_HT-SELEX_1 		0.889 0.889
PAX4
M05431_2.00 		Homo sapiens
NRYTWYACGCWTSRNYRNNYV
BRNNYRNYSAWGCGTRWARYN		 SELEX
Yin et al.(2017)
PAX4_eDBD_HT-SELEX_2 		0.889 0.889
PAX4
M05432_2.00 		Homo sapiens
NTYACGCWYSRNYKMVYN
NRBKMRNYSRWGCGTRAN		 SELEX
Yin et al.(2017)
PAX4_eDBD_HT-SELEX_3 		0.889 0.889
PAX4
M05433_2.00 		Homo sapiens
WHACGSTMATTDR
YHAATKASCGTDW		 SELEX
Yin et al.(2017)
PAX4_eDBD_HT-SELEX_4 		0.889 0.889
PAX4
M10811_2.00 		Homo sapiens
NVNBSNNYVCGCHTSAMBNCN
NGNVKTSADGCGBRNNSVNBN		 Transfac
Matys et al.(2006)
V$PAX4_01 		0.889 0.889
PAX4
M10812_2.00 		Homo sapiens
NAHWAATTDVV
BBHAATTWDTN		 Transfac
Matys et al.(2006)
V$PAX4_02 		0.889 0.889
PAX4
M10813_2.00 		Homo sapiens
NDNNHYCACCCB
VGGGTGRDNNHN		 Transfac
Matys et al.(2006)
V$PAX4_03 		0.889 0.889
PAX4
M10814_2.00 		Homo sapiens
RRAAAWWRNNHHNVHHNVHVNNHHSAYHSB
VSDRTSDDNNBDBNDDBNDDNNYWWTTTYY		 Transfac
Matys et al.(2006)
V$PAX4_04 		0.889 0.889
PAX4
M10815_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX4_Q2 		0.889 0.889
PAX4
M05434_2.00 		Homo sapiens
NHATTANBTAATDN
NHATTAVNTAATDN		 SELEX
Yin et al.(2017)
PAX4_eDBD_Methyl-HT-SELEX_1 		0.889 0.889
PAX4
M05435_2.00 		Homo sapiens
VATTWYACGCWTSRNYDVNYN
NRNBHRNYSAWGCGTRWAATB		 SELEX
Yin et al.(2017)
PAX4_eDBD_Methyl-HT-SELEX_2 		0.889 0.889
PAX4
M05436_2.00 		Homo sapiens
HTYACGCWTSANYGMNYN
NRNKCRNTSAWGCGTRAD		 SELEX
Yin et al.(2017)
PAX4_eDBD_Methyl-HT-SELEX_3 		0.889 0.889
PAX4
M05437_2.00 		Homo sapiens
DHRYGCTAATTAN
NTAATTAGCRYDH		 SELEX
Yin et al.(2017)
PAX4_eDBD_Methyl-HT-SELEX_4 		0.889 0.889
PAX4
M00347_2.00 		Homo sapiens
NNNATND
HNATNNN		 PBM
Barrera et al.(2016)
PAX4_R183C 		0.884 0.884
PAX4
M00348_2.00 		Homo sapiens
NNDATTAN
NTAATHNN		 PBM
Barrera et al.(2016)
PAX4_R192H 		0.884 0.884
PAX4
M00349_2.00 		Homo sapiens
NNNATTANN
NNTAATNNN		 PBM
Barrera et al.(2016)
PAX4_R192S 		0.884 0.884
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSSARP00000004393 Paired box 4 127
ENSSARP00000004393 Homeodomain 169 225

Links

Other Homeodomain,Paired box family TFs
Other Sorex araneus TFs

40 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMEG00000004648 Ailuropoda melanoleuca ENSAMEG00000004648 I 0.928
PAX4 Felis catus ENSFCAG00000005485 I 0.923
PAX4 Equus caballus ENSECAG00000008343 I 0.923
PAX4 Canis familiaris ENSCAFG00000001719 I 0.923
Myotis_brandtii_Pax4_10010526 Myotis brandtii Myotis_brandtii_Pax4_10010526 I 0.917
PAX4 Pteropus vampyrus ENSPVAG00000013944 I 0.912
PAX4 Sus scrofa ENSSSCG00000016591 I 0.912
PAX4 Microcebus murinus ENSMICG00000000095 I 0.912
PAX4 Erinaceus europaeus ENSEEUG00000009616 I 0.912
PAX4 Callithrix jacchus ENSCJAG00000017652 I 0.912
PAX4 Oryctolagus cuniculus ENSOCUG00000001612 I 0.912
ENSOARG00000001951 Ovis aries ENSOARG00000001951 I 0.912
PAX4 Macaca mulatta ENSMMUG00000015429 I 0.907
Pax4 Rattus norvegicus ENSRNOG00000008020 I 0.907
ENSPPYG00000017971 Pongo abelii ENSPPYG00000017971 I 0.907
ENSP00000368014 Macaca fascicularis ENSP00000368014 I 0.907
PAX4 Otolemur garnettii ENSOGAG00000013348 I 0.907
ENSNLEG00000012257 Nomascus leucogenys ENSNLEG00000012257 I 0.906
PAX4 Pan troglodytes ENSPTRG00000019653 I 0.906
PAX4 Gorilla gorilla ENSGGOG00000002555 I 0.906
PAX4 Homo sapiens ENSG00000106331 D 0.906
PAX4 Procavia capensis ENSPCAG00000016257 I 0.901
ENSMPUG00000006575 Mustela putorius furo ENSMPUG00000006575 I 0.901
ENSBTAP00000042667-D1 Bos grunniens ENSBTAP00000042667-D1 I 0.901
PAX4 Bos taurus ENSBTAG00000000410 I 0.896
ENSCSAG00000010195 Chlorocebus sabaeus ENSCSAG00000010195 I 0.895
ENSSTOG00000002127 Ictidomys tridecemlineatus ENSSTOG00000002127 I 0.889
Pax4 Mus musculus ENSMUSG00000029706 D 0.889
PAX4 Cavia porcellus ENSCPOG00000006244 I 0.889
PAX4 Tursiops truncatus ENSTTRG00000006056 I 0.886
PAX4 Loxodonta africana ENSLAFG00000005297 I 0.862
Pax4 Dipodomys ordii ENSDORG00000000332 I 0.856
PAX4 Ochotona princeps ENSOPRG00000013381 I 0.845
ENSSHAG00000015143 Sarcophilus harrisii ENSSHAG00000015143 I 0.834
ENSDNOG00000030639 Dasypus novemcinctus ENSDNOG00000030639 I 0.796
PAX4 Myotis lucifugus ENSMLUG00000030302 I 0.779
PAX4 Choloepus hoffmanni ENSCHOG00000009265 I 0.773
PAX4 Ornithorhynchus anatinus ENSOANG00000000819 I 0.767
Afo_R008534 Aptenodytes forsteri Afo_R008534 I 0.751
Alligator_sinensis_CCG000926.1 Alligator sinensis Alligator_sinensis_CCG000926.1 I 0.740