Hbp1 (Mus musculus)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 ENSMUSG00000002996 T328492_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of lipid transport and negative regulation of reactive oxygen species biosynthetic process. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and neural retina. Orthologous to human HBP1 (HMG-box transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hbp1
M00194_2.00		 Mus musculus
NNNDDNNN
NNNHHNNN		 PBM
Badis et al.(2009)
Hbp1_2241		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HBP1
M11299_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HBP1_Q2 		0.378 1.000
For this family, TFs with SR scores > 0.415 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00194_2.00 Sox 17 84

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000131158 Sox 446 513
ENSMUSP00000131983 Sox 446 474

Links

Other Sox family TFs
Other Mus musculus TFs

163 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
HBP1 Monodelphis domestica ENSMODG00000016376 I 0.741
HBP1 Macaca mulatta ENSMMUG00000015409 I 0.741
HBP1 Myotis lucifugus ENSMLUG00000012425 I 0.741
ENSMPUG00000018249 Mustela putorius furo ENSMPUG00000018249 I 0.741
ENSNLEG00000008761 Nomascus leucogenys ENSNLEG00000008761 I 0.741
ENSOARG00000005055 Ovis aries ENSOARG00000005055 I 0.741
HBP1 Tursiops truncatus ENSTTRG00000006826 I 0.741
HBP1 Microcebus murinus ENSMICG00000012858 I 0.741
HBP1 Vicugna pacos ENSVPAG00000008629 I 0.741
HBP1 Gallus gallus ENSGALG00000008050 I 0.741
ENSXMAG00000016455 Xiphophorus maculatus ENSXMAG00000016455 I 0.741
HBP1 Homo sapiens ENSG00000105856 D 0.741
HBP1 Gorilla gorilla ENSGGOG00000007788 I 0.741
HBP1 Loxodonta africana ENSLAFG00000005317 I 0.741
HBP1 Meleagris gallopavo ENSMGAG00000006880 I 0.741
ENSLOCG00000015822 Lepisosteus oculatus ENSLOCG00000015822 I 0.741
HBP1 Oryctolagus cuniculus ENSOCUG00000012758 I 0.741
HBP1 Otolemur garnettii ENSOGAG00000013102 I 0.741
ENSSHAG00000010948 Sarcophilus harrisii ENSSHAG00000010948 I 0.741
Hbp1 Rattus norvegicus ENSRNOG00000008927 I 0.741
HBP1 Pteropus vampyrus ENSPVAG00000014543 I 0.741
ENSSTOG00000013846 Ictidomys tridecemlineatus ENSSTOG00000013846 I 0.741
hbp1 Tetraodon nigroviridis ENSTNIG00000016027 I 0.741
HBP1 Taeniopygia guttata ENSTGUG00000003100 I 0.741
HBP1 Tupaia belangeri ENSTBEG00000007793 I 0.741
HBP1 Pan troglodytes ENSPTRG00000019575 I 0.741
ENSPSIG00000012478 Pelodiscus sinensis ENSPSIG00000012478 I 0.741
ENSPANG00000024385 Papio anubis ENSPANG00000024385 I 0.741
ENSONIG00000008523 Oreochromis niloticus ENSONIG00000008523 I 0.741
hbp1 Takifugu rubripes ENSTRUG00000016990 I 0.741
HBP1 Procavia capensis ENSPCAG00000014060 I 0.741
ENSPPYG00000017898 Pongo abelii ENSPPYG00000017898 I 0.741
ENSPFOG00000003951 Poecilia formosa ENSPFOG00000003951 I 0.741
HBP1 Felis catus ENSFCAG00000005858 I 0.741
ENSGMOG00000013782 Gadus morhua ENSGMOG00000013782 I 0.741
ENSAMXG00000017678 Astyanax mexicanus ENSAMXG00000017678 I 0.741
ENSAMEG00000013492 Ailuropoda melanoleuca ENSAMEG00000013492 I 0.741
Afo_R001715 Aptenodytes forsteri Afo_R001715 I 0.741
ENSFALG00000010259 Ficedula albicollis ENSFALG00000010259 I 0.741
HBP1 Bos taurus ENSBTAG00000005524 I 0.741
HBP1 Callithrix jacchus ENSCJAG00000016260 I 0.741
Aan_R000440 Calypte anna Aan_R000440 I 0.741
HBP1 Canis familiaris ENSCAFG00000003939 I 0.741
Alligator_sinensis_CCG000124.1 Alligator sinensis Alligator_sinensis_CCG000124.1 I 0.741
Brh_R002687 Buceros rhinoceros Brh_R002687 I 0.741
Myotis_brandtii_HBP1_10033916 Myotis brandtii Myotis_brandtii_HBP1_10033916 I 0.741
Ogr19131 Ophisaurus gracilis Ogr19131 N 0.741
Tal_R010197 Tyto alba Tal_R010197 I 0.741
Gfo_R011321 Geospiza fortis Gfo_R011321 I 0.741
ENSP00000420500 Macaca fascicularis ENSP00000420500 I 0.741
Cmyd_10005373 Chelonia mydas Cmyd_10005373 I 0.741
ENSBTAP00000044156-D1 Bos grunniens ENSBTAP00000044156-D1 I 0.741
HBP1 Cavia porcellus ENSCPOG00000002375 I 0.741
ENSAPLG00000007110 Anas platyrhynchos ENSAPLG00000007110 I 0.741
HBP1 Dasypus novemcinctus ENSDNOG00000004405 I 0.741
hbp1 Danio rerio ENSDARG00000028517 I 0.741
HBP1 Equus caballus ENSECAG00000020969 I 0.741
ENSCSAG00000011395 Chlorocebus sabaeus ENSCSAG00000011395 I 0.741
hbp1 Oryzias latipes ENSORLG00000004396 I 0.739
hbp1.S Xenopus laevis XB-GENE-17342930 I 0.735
HBP1 Anolis carolinensis ENSACAG00000015023 I 0.735
hbp1.L Xenopus laevis XB-GENE-950348 I 0.735
Pvit_03004 Pogona vitticeps Pvit_03004 I 0.735
ENSLACG00000009119 Latimeria chalumnae ENSLACG00000009119 I 0.735
hbp1 Xenopus tropicalis XB-GENE-950343 I 0.735
Hbp1 Dipodomys ordii ENSDORG00000010576 I 0.731
HBP1 Sorex araneus ENSSARG00000007731 I 0.731
ENSMEUG00000011116 Macropus eugenii ENSMEUG00000011116 I 0.731
HBP1 Echinops telfairi ENSETEG00000018542 I 0.731
Ocbimv22007316m.g Octopus bimaculoides Ocbimv22007316m.g N 0.729
HBP1 Ornithorhynchus anatinus ENSOANG00000003174 I 0.728
ENSPFOG00000012271 Poecilia formosa ENSPFOG00000012271 I 0.722
ENSXMAG00000007586 Xiphophorus maculatus ENSXMAG00000007586 I 0.722
ENSONIG00000011868 Oreochromis niloticus ENSONIG00000011868 I 0.716
SMAR013235 Strigamia maritima SMAR013235 I 0.699
ENSGMOG00000014613 Gadus morhua ENSGMOG00000014613 N 0.690
ENSTNIG00000002023 Tetraodon nigroviridis ENSTNIG00000002023 I 0.687
ENSTRUG00000011881 Takifugu rubripes ENSTRUG00000011881 I 0.684
ENSGACG00000019192 Gasterosteus aculeatus ENSGACG00000019192 I 0.671
ENSORLG00000009474 Oryzias latipes ENSORLG00000009474 I 0.655
hbp1 Gasterosteus aculeatus ENSGACG00000010054 I 0.650
e_gw.61.169.1 Branchiostoma floridae e_gw.61.169.1 I 0.639
e_gw.633.29.1 Branchiostoma floridae e_gw.633.29.1 I 0.639
XP_002155149.1 Hydra magnipapillata XP_002155149.1 I 0.611
ENSPMAG00000002631 Petromyzon marinus ENSPMAG00000002631 I 0.610
NEMVEDRAFT_v1g120503 Nematostella vectensis NEMVEDRAFT_v1g120503 I 0.604
TriadG55419 Trichoplax adhaerens TriadG55419 I 0.603
GH23191 Drosophila grimshawi FBgn0130648 N 0.602
SPU_021407 Strongylocentrotus purpuratus SPU_021407 N 0.587
ISCW021979 Ixodes scapularis ISCW021979 I 0.568
CGI_10003963 Crassostrea gigas CGI_10003963 I 0.566
DAPPUDRAFT_313324 Daphnia pulex DAPPUDRAFT_313324 I 0.551
PHUM534240 Pediculus humanus PHUM534240 I 0.549
ENSCPOG00000024750 Cavia porcellus ENSCPOG00000024750 I 0.546
ML040423a Mnemiopsis leidyi ML040423a I 0.544
BBX Homo sapiens ENSG00000114439 D 0.539
L798_09303 Zootermopsis nevadensis L798_09303 I 0.526
DAPPUDRAFT_346928 Daphnia pulex DAPPUDRAFT_346928 N 0.494
SPOG_05006 Schizosaccharomyces cryophilus SPOG_05006 N 0.492
PredSwiss_ASS2010_3146.2 Pneumocystis carinii PredSwiss_ASS2010_3146.2 N 0.492
PPA10381 Pristionchus pacificus PPA10381 N 0.491
Bra012244 Brassica rapa Bra012244 N 0.478
GLYMA03G08270 Glycine max GLYMA03G08270 I 0.478
Bra016455 Brassica rapa Bra016455 N 0.478
ENSTNIG00000011238 Tetraodon nigroviridis ENSTNIG00000011238 N 0.476
L798_09360 Zootermopsis nevadensis L798_09360 N 0.465
HelroG148167 Helobdella robusta HelroG148167 I 0.465
L798_04020 Zootermopsis nevadensis L798_04020 N 0.465
RO3G_14677 Rhizopus oryzae RO3G_14677 N 0.463
CaO19.1730 Candida albicans CaO19.1730 N 0.463
CaO19.9298 Candida albicans CaO19.9298 N 0.463
PXEA_0001829801 Protopolystoma xenopodis PXEA_0001829801 N 0.462
SOX11 Ornithorhynchus anatinus ENSOANG00000006361 N 0.462
GLYMA02G25940 Glycine max GLYMA02G25940 N 0.462
Sjc_0095610 Schistosoma japonicum Sjc_0095610 N 0.462
ENSTNIG00000019242 Tetraodon nigroviridis ENSTNIG00000019242 N 0.457
SNAPOd2T00000335001 Oikopleura dioica SNAPOd2T00000335001 I 0.457
e_gw1.88.21.1 Fragilariopsis cylindrus e_gw1.88.21.1 N 0.453
GLOINDRAFT_28614 Rhizophagus irregularis GLOINDRAFT_28614 N 0.449
Ocbimv22020621m.g Octopus bimaculoides Ocbimv22020621m.g N 0.448
GL20955 Drosophila persimilis FBgn0158550 I 0.445
SOX9 Dasypus novemcinctus ENSDNOG00000033826 I 0.445
DICSQDRAFT_40774 Dichomitus squalens DICSQDRAFT_40774 I 0.443
ECPE_0001539401 Echinostoma caproni ECPE_0001539401 I 0.443
GB51010 Apis mellifera GB51010 I 0.438
SPER_0000213401 Spirometra erinaceieuropaei SPER_0000213401 N 0.436
ZYRO0C16214g Zygosaccharomyces rouxii ZYRO0C16214g I 0.435
ZBAI_00389 Zygosaccharomyces bailii ZBAI_00389 I 0.435
ZBAI_05541 Zygosaccharomyces bailii ZBAI_05541 I 0.435
D915_09544 Fasciola hepatica D915_09544 I 0.434
ACEP25270 Atta cephalotes ACEP25270 N 0.433
GI22721 Drosophila mojavensis FBgn0145448 I 0.432
csin104163 Clonorchis sinensis csin104163 I 0.432
T265_01499 Opisthorchis viverrini T265_01499 I 0.432
AGOS_AAR026W Ashbya gossypii AGOS_AAR026W I 0.429
tetur23g00840 Tetranychus urticae tetur23g00840 I 0.428
GA30228 Drosophila pseudoobscura FBgn0263363 I 0.425
GL12097 Drosophila persimilis FBgn0149705 I 0.425
ENSTSYG00000010057 Tarsius syrichta ENSTSYG00000010057 I 0.425
AACERI_AaceriAAR026W Saccharomycetaceae sp ashbya aceri AACERI_AaceriAAR026W I 0.420
Ecym_1257 Eremothecium cymbalariae Ecym_1257 I 0.420
TCLT_0000083701 Thelazia callipaeda TCLT_0000083701 I 0.419
ADIR005630 Anopheles dirus ADIR005630 I 0.419
ANCDUO_25812 Ancylostoma duodenale ANCDUO_25812 N 0.419
SOX6 Tupaia belangeri ENSTBEG00000002476 I 0.419
SOX13 Microcebus murinus ENSMICG00000009236 I 0.419
SOX6 Procavia capensis ENSPCAG00000001398 N 0.419
ENSMEUG00000008151 Macropus eugenii ENSMEUG00000008151 I 0.419
SOX6 Echinops telfairi ENSETEG00000001898 I 0.419
SOX6 Choloepus hoffmanni ENSCHOG00000005751 I 0.419
SOX6 Erinaceus europaeus ENSEEUG00000006749 I 0.419
SOX17 Procavia capensis ENSPCAG00000003188 I 0.419
SOX5 Sorex araneus ENSSARG00000007963 I 0.419
SMAR010127 Strigamia maritima SMAR010127 N 0.419
SEPMUDRAFT_152382 Sphaerulina musiva SEPMUDRAFT_152382 N 0.419
MESCA000459 Megaselia scalaris MESCA000459 I 0.419
ENSTSYG00000012536 Tarsius syrichta ENSTSYG00000012536 I 0.419
PHACADRAFT_58554 Phanerochaete carnosa PHACADRAFT_58554 N 0.417
Smp_148110 Schistosoma mansoni Smp_148110 I 0.417
NECAME_00080 Necator americanus NECAME_00080 I 0.416
H101_08199 Trichophyton interdigitale H101_08199 N 0.416
HelroG148142 Helobdella robusta HelroG148142 I 0.416
CANTEDRAFT_136140 Candida tenuis CANTEDRAFT_136140 I 0.415