HBP1 (Homo sapiens)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 ENSG00000105856 T328060_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of lipid transport; negative regulation of reactive oxygen species biosynthetic process; and negative regulation of transcription by RNA polymerase II. Located in nuclear speck. Biomarker of osteoarthritis. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HBP1
M11299_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HBP1_Q2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Hbp1
M00194_2.00 		Mus musculus
NNNDDNNN
NNNHHNNN		 PBM
Badis et al.(2009)
Hbp1_2241 		0.741 1.000
For this family, TFs with SR scores > 0.415 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000222574 Sox 434 501
ENSP00000418017 Sox 426 454
ENSP00000418738 Sox 434 501
ENSP00000419143 Sox 29 67
ENSP00000420500 Sox 434 501
ENSP00000475809 Sox 74 141

Links

Other Sox family TFs
Other Homo sapiens TFs

241 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSOARG00000005055 Ovis aries ENSOARG00000005055 I 0.741
ENSNLEG00000008761 Nomascus leucogenys ENSNLEG00000008761 I 0.741
Hbp1 Mus musculus ENSMUSG00000002996 D 0.741
ENSMPUG00000018249 Mustela putorius furo ENSMPUG00000018249 I 0.741
HBP1 Oryctolagus cuniculus ENSOCUG00000012758 I 0.741
HBP1 Otolemur garnettii ENSOGAG00000013102 I 0.741
ENSPFOG00000003951 Poecilia formosa ENSPFOG00000003951 I 0.741
HBP1 Procavia capensis ENSPCAG00000014060 I 0.741
ENSPANG00000024385 Papio anubis ENSPANG00000024385 I 0.741
ENSONIG00000008523 Oreochromis niloticus ENSONIG00000008523 I 0.741
HBP1 Monodelphis domestica ENSMODG00000016376 I 0.741
HBP1 Macaca mulatta ENSMMUG00000015409 I 0.741
HBP1 Gorilla gorilla ENSGGOG00000007788 I 0.741
HBP1 Gallus gallus ENSGALG00000008050 I 0.741
HBP1 Felis catus ENSFCAG00000005858 I 0.741
ENSGMOG00000013782 Gadus morhua ENSGMOG00000013782 I 0.741
HBP1 Loxodonta africana ENSLAFG00000005317 I 0.741
HBP1 Myotis lucifugus ENSMLUG00000012425 I 0.741
HBP1 Microcebus murinus ENSMICG00000012858 I 0.741
HBP1 Meleagris gallopavo ENSMGAG00000006880 I 0.741
ENSLOCG00000015822 Lepisosteus oculatus ENSLOCG00000015822 I 0.741
ENSPPYG00000017898 Pongo abelii ENSPPYG00000017898 I 0.741
ENSPSIG00000012478 Pelodiscus sinensis ENSPSIG00000012478 I 0.741
Cmyd_10005373 Chelonia mydas Cmyd_10005373 I 0.741
Brh_R002687 Buceros rhinoceros Brh_R002687 I 0.741
Alligator_sinensis_CCG000124.1 Alligator sinensis Alligator_sinensis_CCG000124.1 I 0.741
Afo_R001715 Aptenodytes forsteri Afo_R001715 I 0.741
ENSBTAP00000044156-D1 Bos grunniens ENSBTAP00000044156-D1 I 0.741
ENSP00000420500 Macaca fascicularis ENSP00000420500 I 0.741
Tal_R010197 Tyto alba Tal_R010197 I 0.741
Ogr19131 Ophisaurus gracilis Ogr19131 N 0.741
Myotis_brandtii_HBP1_10033916 Myotis brandtii Myotis_brandtii_HBP1_10033916 I 0.741
Gfo_R011321 Geospiza fortis Gfo_R011321 I 0.741
Aan_R000440 Calypte anna Aan_R000440 I 0.741
ENSXMAG00000016455 Xiphophorus maculatus ENSXMAG00000016455 I 0.741
ENSSHAG00000010948 Sarcophilus harrisii ENSSHAG00000010948 I 0.741
Hbp1 Rattus norvegicus ENSRNOG00000008927 I 0.741
HBP1 Pteropus vampyrus ENSPVAG00000014543 I 0.741
HBP1 Pan troglodytes ENSPTRG00000019575 I 0.741
ENSSTOG00000013846 Ictidomys tridecemlineatus ENSSTOG00000013846 I 0.741
HBP1 Tupaia belangeri ENSTBEG00000007793 I 0.741
HBP1 Vicugna pacos ENSVPAG00000008629 I 0.741
hbp1 Takifugu rubripes ENSTRUG00000016990 I 0.741
hbp1 Tetraodon nigroviridis ENSTNIG00000016027 I 0.741
HBP1 Taeniopygia guttata ENSTGUG00000003100 I 0.741
ENSFALG00000010259 Ficedula albicollis ENSFALG00000010259 I 0.741
HBP1 Tursiops truncatus ENSTTRG00000006826 I 0.741
HBP1 Cavia porcellus ENSCPOG00000002375 I 0.741
ENSCSAG00000011395 Chlorocebus sabaeus ENSCSAG00000011395 I 0.741
hbp1 Danio rerio ENSDARG00000028517 I 0.741
HBP1 Callithrix jacchus ENSCJAG00000016260 I 0.741
HBP1 Canis familiaris ENSCAFG00000003939 I 0.741
ENSAMEG00000013492 Ailuropoda melanoleuca ENSAMEG00000013492 I 0.741
ENSAMXG00000017678 Astyanax mexicanus ENSAMXG00000017678 I 0.741
HBP1 Bos taurus ENSBTAG00000005524 I 0.741
HBP1 Dasypus novemcinctus ENSDNOG00000004405 I 0.741
ENSAPLG00000007110 Anas platyrhynchos ENSAPLG00000007110 I 0.741
HBP1 Equus caballus ENSECAG00000020969 I 0.741
hbp1 Oryzias latipes ENSORLG00000004396 I 0.739
hbp1.S Xenopus laevis XB-GENE-17342930 I 0.735
hbp1.L Xenopus laevis XB-GENE-950348 I 0.735
Pvit_03004 Pogona vitticeps Pvit_03004 I 0.735
hbp1 Xenopus tropicalis XB-GENE-950343 I 0.735
HBP1 Anolis carolinensis ENSACAG00000015023 I 0.735
ENSLACG00000009119 Latimeria chalumnae ENSLACG00000009119 I 0.735
HBP1 Echinops telfairi ENSETEG00000018542 I 0.731
HBP1 Sorex araneus ENSSARG00000007731 I 0.731
ENSMEUG00000011116 Macropus eugenii ENSMEUG00000011116 I 0.731
Hbp1 Dipodomys ordii ENSDORG00000010576 I 0.731
Ocbimv22007316m.g Octopus bimaculoides Ocbimv22007316m.g N 0.729
HBP1 Ornithorhynchus anatinus ENSOANG00000003174 I 0.728
ENSXMAG00000007586 Xiphophorus maculatus ENSXMAG00000007586 I 0.722
ENSPFOG00000012271 Poecilia formosa ENSPFOG00000012271 I 0.722
ENSONIG00000011868 Oreochromis niloticus ENSONIG00000011868 I 0.716
SMAR013235 Strigamia maritima SMAR013235 I 0.699
ENSGMOG00000014613 Gadus morhua ENSGMOG00000014613 N 0.690
ENSTNIG00000002023 Tetraodon nigroviridis ENSTNIG00000002023 I 0.687
ENSTRUG00000011881 Takifugu rubripes ENSTRUG00000011881 I 0.684
ENSGACG00000019192 Gasterosteus aculeatus ENSGACG00000019192 I 0.671
ENSORLG00000009474 Oryzias latipes ENSORLG00000009474 I 0.655
hbp1 Gasterosteus aculeatus ENSGACG00000010054 I 0.650
e_gw.61.169.1 Branchiostoma floridae e_gw.61.169.1 I 0.639
e_gw.633.29.1 Branchiostoma floridae e_gw.633.29.1 I 0.639
XP_002155149.1 Hydra magnipapillata XP_002155149.1 I 0.611
ENSPMAG00000002631 Petromyzon marinus ENSPMAG00000002631 I 0.610
NEMVEDRAFT_v1g120503 Nematostella vectensis NEMVEDRAFT_v1g120503 I 0.604
TriadG55419 Trichoplax adhaerens TriadG55419 I 0.603
GH23191 Drosophila grimshawi FBgn0130648 N 0.602
SPU_021407 Strongylocentrotus purpuratus SPU_021407 N 0.587
ISCW021979 Ixodes scapularis ISCW021979 I 0.568
CGI_10003963 Crassostrea gigas CGI_10003963 I 0.566
DAPPUDRAFT_313324 Daphnia pulex DAPPUDRAFT_313324 I 0.551
PHUM534240 Pediculus humanus PHUM534240 I 0.549
ENSCPOG00000024750 Cavia porcellus ENSCPOG00000024750 I 0.546
ML040423a Mnemiopsis leidyi ML040423a I 0.544
BBX Homo sapiens ENSG00000114439 D 0.539
L798_09303 Zootermopsis nevadensis L798_09303 I 0.526
HelroG148167 Helobdella robusta HelroG148167 I 0.498
DAPPUDRAFT_346928 Daphnia pulex DAPPUDRAFT_346928 N 0.494
PredSwiss_ASS2010_3146.2 Pneumocystis carinii PredSwiss_ASS2010_3146.2 N 0.492
SPOG_05006 Schizosaccharomyces cryophilus SPOG_05006 N 0.492
PHACADRAFT_58554 Phanerochaete carnosa PHACADRAFT_58554 N 0.492
PPA10381 Pristionchus pacificus PPA10381 N 0.491
GLOINDRAFT_28614 Rhizophagus irregularis GLOINDRAFT_28614 N 0.485
L798_09360 Zootermopsis nevadensis L798_09360 N 0.483
L798_04020 Zootermopsis nevadensis L798_04020 N 0.483
GLYMA03G08270 Glycine max GLYMA03G08270 I 0.478
Bra012244 Brassica rapa Bra012244 N 0.478
Bra016455 Brassica rapa Bra016455 N 0.478
ENSTNIG00000011238 Tetraodon nigroviridis ENSTNIG00000011238 N 0.476
orange1.1g029982m.g Citrus sinensis orange1.1g029982m.g I 0.472
GRMZM2G144398 Zea mays GRMZM2G144398 N 0.472
XM_002306945.1 Populus trichocarpa POPTR_0005s27390 I 0.472
SOX9 Dasypus novemcinctus ENSDNOG00000033826 I 0.469
Ocbimv22020621m.g Octopus bimaculoides Ocbimv22020621m.g N 0.466
MPER_07337 Moniliophthora perniciosa MPER_07337 N 0.464
M404DRAFT_79773 Pisolithus tinctorius M404DRAFT_79773 N 0.464
CaO19.9298 Candida albicans CaO19.9298 N 0.463
CaO19.1730 Candida albicans CaO19.1730 N 0.463
RO3G_14677 Rhizopus oryzae RO3G_14677 N 0.463
GLYMA02G25940 Glycine max GLYMA02G25940 N 0.462
SOX11 Ornithorhynchus anatinus ENSOANG00000006361 N 0.462
PXEA_0001829801 Protopolystoma xenopodis PXEA_0001829801 N 0.462
Sjc_0095610 Schistosoma japonicum Sjc_0095610 N 0.462
SPER_0000213401 Spirometra erinaceieuropaei SPER_0000213401 N 0.460
ACEP25270 Atta cephalotes ACEP25270 N 0.457
SNAPOd2T00000335001 Oikopleura dioica SNAPOd2T00000335001 I 0.457
ENSTNIG00000019242 Tetraodon nigroviridis ENSTNIG00000019242 N 0.457
GLYMA01G28253 Glycine max GLYMA01G28253 N 0.455
e_gw1.88.21.1 Fragilariopsis cylindrus e_gw1.88.21.1 N 0.453
NECAME_00080 Necator americanus NECAME_00080 I 0.449
HelroG148142 Helobdella robusta HelroG148142 I 0.449
CY34DRAFT_106474 Suillus luteus CY34DRAFT_106474 N 0.446
PK25712.1 Cannabis sativa PK25712.1 N 0.446
GL20955 Drosophila persimilis FBgn0158550 I 0.445
ENSTRUG00000006849 Takifugu rubripes ENSTRUG00000006849 N 0.445
RPRC012125 Rhodnius prolixus RPRC012125 N 0.444
ACUA008554 Anopheles culicifacies ACUA008554 I 0.444
DICSQDRAFT_40774 Dichomitus squalens DICSQDRAFT_40774 I 0.443
ECPE_0001539401 Echinostoma caproni ECPE_0001539401 I 0.443
BOTBODRAFT_575815 Botryobasidium botryosum BOTBODRAFT_575815 N 0.440
GB51010 Apis mellifera GB51010 I 0.438
RSKR_0000394100 Rhabditophanes kr3021 RSKR_0000394100 N 0.438
AARA000827 Anopheles arabiensis AARA000827 I 0.437
SOX6 Erinaceus europaeus ENSEEUG00000006749 I 0.437
Cflo_01077--XP_001122045.1_APIME Camponotus floridanus Cflo_01077--XP_001122045.1_APIME N 0.437
ACEP25857 Atta cephalotes ACEP25857 I 0.437
ADIR005630 Anopheles dirus ADIR005630 I 0.437
AEPI003628 Anopheles epiroticus AEPI003628 I 0.437
YQE_13042 Dendroctonus ponderosae YQE_13042 I 0.437
LCUP001585 Lucilia cuprina LCUP001585 I 0.437
ADIR009659 Anopheles dirus ADIR009659 I 0.437
ACEP10855 Atta cephalotes ACEP10855 I 0.437
SOX6 Tupaia belangeri ENSTBEG00000002476 I 0.437
AGAP012033 Anopheles gambiae AGAP012033 I 0.437
AAEL000792 Aedes aegypti AAEL000792 I 0.437
CpipJ_CPIJ012500 Culex pipiens CpipJ_CPIJ012500 N 0.437
SOX13 Microcebus murinus ENSMICG00000009236 I 0.437
ENSMEUG00000008151 Macropus eugenii ENSMEUG00000008151 I 0.437
SOX13 Felis catus ENSFCAG00000002900 I 0.437
ACOM022800 Anopheles coluzzii ACOM022800 I 0.437
ACOM026664 Anopheles coluzzii ACOM026664 N 0.437
LDEC007549 Leptinotarsa decemlineata LDEC007549 N 0.437
SOX6 Echinops telfairi ENSETEG00000001898 I 0.437
SOX6 Choloepus hoffmanni ENSCHOG00000005751 I 0.437
Hsal_04214--XP_001122045.1_APIME Harpegnathos saltator Hsal_04214--XP_001122045.1_APIME N 0.437
AARA005391 Anopheles arabiensis AARA005391 I 0.437
ACUA011783 Anopheles culicifacies ACUA011783 N 0.437
PHUM433270 Pediculus humanus PHUM433270 N 0.437
NBR_0000360901 Nippostrongylus brasiliensis NBR_0000360901 I 0.437
CPIJ012500 Culex quinquefasciatus CPIJ012500 N 0.437
GB40960 Apis mellifera GB40960 I 0.437
HMEL016850 Heliconius melpomene HMEL016850 I 0.437
D918_08316 Trichuris suis D918_08316 N 0.437
ANCDUO_25812 Ancylostoma duodenale ANCDUO_25812 N 0.437
KGM_05609 Danaus plexippus KGM_05609 N 0.437
NBR_0002216901 Nippostrongylus brasiliensis NBR_0002216901 I 0.437
CPIJ012042 Culex quinquefasciatus CPIJ012042 I 0.437
SOX12 Sus scrofa ENSSSCG00000021920 I 0.437
TCLT_0000083701 Thelazia callipaeda TCLT_0000083701 I 0.437
ENSTGUG00000002931 Taeniopygia guttata ENSTGUG00000002931 I 0.437
ENSTSYG00000012536 Tarsius syrichta ENSTSYG00000012536 I 0.437
CpipJ_CPIJ012042 Culex pipiens CpipJ_CPIJ012042 I 0.437
BGIBMGA003080 Bombyx mori BGIBMGA003080 I 0.437
SOX5 Sorex araneus ENSSARG00000007963 I 0.437
LLOJ005525 Lutzomyia longipalpis LLOJ005525 I 0.437
BGLB002734 Biomphalaria glabrata BGLB002734 I 0.437
SMAR010127 Strigamia maritima SMAR010127 N 0.437
SINV16626 Solenopsis invicta SINV16626 I 0.437
AMIN009301 Anopheles minimus AMIN009301 I 0.437
AMEM014190 Anopheles merus AMEM014190 I 0.437
AMEC014560 Anopheles melas AMEC014560 I 0.437
AMAM006332 Anopheles maculatus AMAM006332 I 0.437
AMEC012053 Anopheles melas AMEC012053 I 0.437
AQUA001262 Anopheles quadriannulatus AQUA001262 I 0.437
SOX6 Procavia capensis ENSPCAG00000001398 N 0.437
MCINX002905 Melitaea cinxia MCINX002905 I 0.437
ASTEI06407 Anopheles stephensi ASTEI06407 I 0.437
MESCA000459 Megaselia scalaris MESCA000459 I 0.437
ASIS016076 Anopheles sinensis ASIS016076 N 0.437
AALB009868 Anopheles albimanus AALB009868 I 0.437
SOX17 Procavia capensis ENSPCAG00000003188 I 0.437
AFUN009319 Anopheles funestus AFUN009319 I 0.437
ZYRO0C16214g Zygosaccharomyces rouxii ZYRO0C16214g I 0.435
ZBAI_00389 Zygosaccharomyces bailii ZBAI_00389 I 0.435
ZBAI_05541 Zygosaccharomyces bailii ZBAI_05541 I 0.435
GPUH_0001196001 Gongylonema pulchrum GPUH_0001196001 N 0.434
GPUH_0000691201 Gongylonema pulchrum GPUH_0000691201 N 0.434
D915_09544 Fasciola hepatica D915_09544 I 0.434
TPHA_0C04350 Tetrapisispora phaffii TPHA_0C04350 N 0.432
GI22721 Drosophila mojavensis FBgn0145448 I 0.432
csin104163 Clonorchis sinensis csin104163 I 0.432
T265_01499 Opisthorchis viverrini T265_01499 I 0.432
AGOS_AAR026W Ashbya gossypii AGOS_AAR026W I 0.429
tetur23g00840 Tetranychus urticae tetur23g00840 I 0.428
GA30228 Drosophila pseudoobscura FBgn0263363 I 0.425
GL12097 Drosophila persimilis FBgn0149705 I 0.425
ENSTSYG00000010057 Tarsius syrichta ENSTSYG00000010057 I 0.425
DAPPUDRAFT_37735 Daphnia pulex DAPPUDRAFT_37735 I 0.424
SOX9 Pteropus vampyrus ENSPVAG00000010505 I 0.423
SOX10 Erinaceus europaeus ENSEEUG00000011263 I 0.423
ENSDORG00000003967 Dipodomys ordii ENSDORG00000003967 I 0.423
ENSDORG00000012440 Dipodomys ordii ENSDORG00000012440 I 0.423
SOX10 Procavia capensis ENSPCAG00000005913 I 0.423
SOX10 Ochotona princeps ENSOPRG00000013575 I 0.423
ENSVPAG00000000908 Vicugna pacos ENSVPAG00000000908 I 0.423
ISCW009925 Ixodes scapularis ISCW009925 I 0.420
LotgiG88815 Lottia gigantea LotgiG88815 I 0.420
AACERI_AaceriAAR026W Saccharomycetaceae sp ashbya aceri AACERI_AaceriAAR026W I 0.420
Ecym_1257 Eremothecium cymbalariae Ecym_1257 I 0.420
BGLB010904 Biomphalaria glabrata BGLB010904 I 0.420
ENSPMAG00000010371 Petromyzon marinus ENSPMAG00000010371 I 0.420
SEPMUDRAFT_152382 Sphaerulina musiva SEPMUDRAFT_152382 N 0.419
RO3G_05566 Rhizopus oryzae RO3G_05566 N 0.417
ENSLOCG00000004648 Lepisosteus oculatus ENSLOCG00000004648 I 0.417
Smp_148110 Schistosoma mansoni Smp_148110 I 0.417
EFV48447 Trichinella spiralis EFV48447 I 0.417
AC186524.3_FG005 Zea mays AC186524.3_FG005 N 0.416
H101_08199 Trichophyton interdigitale H101_08199 N 0.416
CANTEDRAFT_136140 Candida tenuis CANTEDRAFT_136140 I 0.415