si:dkey-222b8.1 (Danio rerio)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSDARG00000045094 T324561_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.961 0.961
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.961 0.961
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.961 0.961
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.961 0.961
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.961 0.961
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.961 0.961
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.961 0.961
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.922 0.922
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.922 0.922
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000047861 SMAD 32 133
ENSDARP00000120222 SMAD 32 133

Links

Other SMAD family TFs
Other Danio rerio TFs

209 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SMAD4 Homo sapiens ENSG00000141646 D 0.982
Smad4 Mus musculus ENSMUSG00000024515 D 0.961
Med Drosophila melanogaster FBgn0011655 D 0.922
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.922
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.765
AAEL013896 Aedes aegypti AAEL013896 I 0.931
ACEP19585 Atta cephalotes ACEP19585 I 0.804
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.922
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.873
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.863
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.863
ADAC007516 Anopheles darlingi ADAC007516 I 0.912
AGAP002902 Anopheles gambiae AGAP002902 I 0.931
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.843
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.843
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.735
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.931
Bm3575 Brugia malayi Bm3575 I 0.775
CapteG179368 Capitella teleta CapteG179368 I 0.912
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.804
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.922
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.931
EFV62078 Trichinella spiralis EFV62078 I 0.814
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.961
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.961
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 1.000
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 1.000
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.951
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.961
SMAD4 Bos taurus ENSBTAG00000006919 I 0.961
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.961
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.961
smad4 Ciona intestinalis ENSCING00000005559 I 0.892
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.961
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.961
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.961
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.892
SMAD4 Danio rerio ENSDARG00000012649 I 0.951
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.990
smad4a Danio rerio ENSDARG00000075226 I 0.951
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.961
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.960
SMAD4 Equus caballus ENSECAG00000017857 I 0.961
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.961
SMAD4 Felis catus ENSFCAG00000005257 I 0.961
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 1.000
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.912
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.961
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.961
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.961
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.990
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.961
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.961
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.961
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.961
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.765
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.931
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.961
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.961
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.961
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.961
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.961
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.961
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.961
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.961
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.961
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.961
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.961
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.980
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.961
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.951
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.961
smad4a Oryzias latipes ENSORLG00000005020 I 0.951
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.951
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.961
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.951
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.951
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.922
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.941
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.931
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.961
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.961
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.961
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.961
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.961
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.961
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.961
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.961
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.931
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.912
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.951
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 1.000
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.931
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.951
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.961
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.961
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.951
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.951
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.922
GF22974 Drosophila ananassae FBgn0099968 I 0.922
GG11819 Drosophila erecta FBgn0104114 I 0.922
GH18642 Drosophila grimshawi FBgn0126109 I 0.922
GI23400 Drosophila mojavensis FBgn0146126 I 0.922
GL23637 Drosophila persimilis FBgn0161227 I 0.922
GM16436 Drosophila sechellia FBgn0171351 I 0.922
GJ23092 Drosophila virilis FBgn0210194 I 0.922
GK11724 Drosophila willistoni FBgn0213735 I 0.922
GE10952 Drosophila yakuba FBgn0228782 I 0.922
GB50071 Apis mellifera GB50071 I 0.922
HelroG76435 Helobdella robusta HelroG76435 I 0.794
HelroG88197 Helobdella robusta HelroG88197 I 0.853
HMEL002203 Heliconius melpomene HMEL002203 I 0.931
ISCW018468 Ixodes scapularis ISCW018468 I 0.941
KGM_12572 Danaus plexippus KGM_12572 I 0.931
L798_13939 Zootermopsis nevadensis L798_13939 I 0.931
LOAG_08923 Loa loa LOAG_08923 I 0.755
LotgiG131078 Lottia gigantea LotgiG131078 I 0.931
MCINX014520 Melitaea cinxia MCINX014520 I 0.931
ML02191a Mnemiopsis leidyi ML02191a I 0.853
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.765
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.902
NV12984 Nasonia vitripennis NV12984 I 0.922
PHUM002670 Pediculus humanus PHUM002670 I 0.931
RPRC010188 Rhodnius prolixus RPRC010188 I 0.922
SINV15516 Solenopsis invicta SINV15516 I 0.922
SMAR013850 Strigamia maritima SMAR013850 I 0.931
Smp_033950 Schistosoma mansoni Smp_033950 I 0.725
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.922
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.855
TC010848 Tribolium castaneum TC010848 I 0.922
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.767
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.902
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.804
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.755
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.912
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.873
Aan_R014474 Calypte anna Aan_R014474 I 0.828
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.961
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.873
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.961
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.961
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.922
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.961
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.961
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.961
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.961
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.961
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.922
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.961
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.971
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.961
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.961
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.951
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.912
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.931
Sakowv30001112m.g Saccoglossus kowalevskii Sakowv30001112m.g I 0.731
AAH84196 Xenopus laevis AAH84196 I 0.961
CLEC002594 Cimex lectularius CLEC002594 I 0.922
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.931
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.922
LCUP007928 Lucilia cuprina LCUP007928 I 0.922
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.922
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.755
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.814
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.961
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.980
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.980
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.961
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.863
AALB009485 Anopheles albimanus AALB009485 I 0.912
AARA004719 Anopheles arabiensis AARA004719 I 0.931
AATE010695 Anopheles atroparvus AATE010695 I 0.931
ACHR000067 Anopheles christyi ACHR000067 I 0.931
ACOM037505 Anopheles coluzzii ACOM037505 I 0.931
ACUA025512 Anopheles culicifacies ACUA025512 I 0.931
ADIR002761 Anopheles dirus ADIR002761 I 0.931
AEPI002385 Anopheles epiroticus AEPI002385 I 0.931
AFAF011208 Anopheles farauti AFAF011208 I 0.931
AFUN009864 Anopheles funestus AFUN009864 I 0.931
AMAM019778 Anopheles maculatus AMAM019778 I 0.931
AMEM015931 Anopheles merus AMEM015931 I 0.931
AMIN000723 Anopheles minimus AMIN000723 I 0.931
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.931
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.931
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.941
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.941
MDOA012885 Musca domestica MDOA012885 I 0.922
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.941
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.794
ASU_13433 Ascaris suum ASU_13433 I 0.765
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.775
D915_03789 Fasciola hepatica D915_03789 I 0.804
D917_09719 Trichinella nativa D917_09719 I 0.814
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.794
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.765
GPLIN_000772200 Globodera pallida GPLIN_000772200 I 0.716
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.784
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.765
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.765
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.765
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.755
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.725
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.716
T265_11013 Opisthorchis viverrini T265_11013 I 0.804
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.755
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.824
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.775
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.824