smad4a (Gasterosteus aculeatus)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSGACG00000007495 T324636_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.980 0.980
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.980 0.980
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.980 0.980
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.980 0.980
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.980 0.980
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.980 0.980
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.980 0.980
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.961 0.961
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.961 0.961
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSGACP00000009949 SMAD 34 135
ENSGACP00000009957 SMAD 33 134

Links

Other SMAD family TFs
Other Gasterosteus aculeatus TFs

204 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SMAD4 Homo sapiens ENSG00000141646 D 0.980
Smad4 Mus musculus ENSMUSG00000024515 D 0.980
Med Drosophila melanogaster FBgn0011655 D 0.961
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.961
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.775
AAEL013896 Aedes aegypti AAEL013896 I 0.971
ACEP19585 Atta cephalotes ACEP19585 I 0.843
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.931
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.882
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.853
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.873
ADAC007516 Anopheles darlingi ADAC007516 I 0.931
AGAP002902 Anopheles gambiae AGAP002902 I 0.951
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.843
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.843
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.725
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.951
Bm3575 Brugia malayi Bm3575 I 0.784
CapteG179368 Capitella teleta CapteG179368 I 0.941
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.961
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.951
EFV62078 Trichinella spiralis EFV62078 I 0.814
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.980
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.980
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.961
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.961
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.990
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.980
SMAD4 Bos taurus ENSBTAG00000006919 I 0.980
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.980
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.980
smad4 Ciona intestinalis ENSCING00000005559 I 0.922
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.980
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.980
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.980
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.922
SMAD4 Danio rerio ENSDARG00000012649 I 0.990
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.961
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.951
smad4a Danio rerio ENSDARG00000075226 I 0.990
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.980
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.971
SMAD4 Equus caballus ENSECAG00000017857 I 0.980
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.980
SMAD4 Felis catus ENSFCAG00000005257 I 0.980
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.961
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.902
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.980
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.980
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.951
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 1.000
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.971
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.961
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.980
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.784
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.951
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.980
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.980
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.980
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.980
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.980
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.980
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.980
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.980
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.980
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.980
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.941
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.941
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.980
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.990
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.980
smad4a Oryzias latipes ENSORLG00000005020 I 0.990
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.971
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.980
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.990
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.971
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.902
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.931
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.922
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.980
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.980
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.980
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.980
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.980
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.980
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.980
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.980
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.961
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.902
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.971
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.961
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.961
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.971
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.980
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.980
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.971
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.990
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.961
GF22974 Drosophila ananassae FBgn0099968 I 0.961
GG11819 Drosophila erecta FBgn0104114 I 0.961
GH18642 Drosophila grimshawi FBgn0126109 I 0.961
GI23400 Drosophila mojavensis FBgn0146126 I 0.961
GL23637 Drosophila persimilis FBgn0161227 I 0.961
GM16436 Drosophila sechellia FBgn0171351 I 0.961
GJ23092 Drosophila virilis FBgn0210194 I 0.961
GK11724 Drosophila willistoni FBgn0213735 I 0.961
GE10952 Drosophila yakuba FBgn0228782 I 0.961
GB50071 Apis mellifera GB50071 I 0.961
HelroG76435 Helobdella robusta HelroG76435 I 0.794
HelroG88197 Helobdella robusta HelroG88197 I 0.863
HMEL002203 Heliconius melpomene HMEL002203 I 0.951
ISCW018468 Ixodes scapularis ISCW018468 I 0.961
KGM_12572 Danaus plexippus KGM_12572 I 0.951
L798_13939 Zootermopsis nevadensis L798_13939 I 0.971
LOAG_08923 Loa loa LOAG_08923 I 0.765
LotgiG131078 Lottia gigantea LotgiG131078 I 0.922
MCINX014520 Melitaea cinxia MCINX014520 I 0.951
ML02191a Mnemiopsis leidyi ML02191a I 0.853
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.765
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.931
NV12984 Nasonia vitripennis NV12984 I 0.961
PHUM002670 Pediculus humanus PHUM002670 I 0.971
RPRC010188 Rhodnius prolixus RPRC010188 I 0.951
SINV15516 Solenopsis invicta SINV15516 I 0.961
SMAR013850 Strigamia maritima SMAR013850 I 0.971
Smp_033950 Schistosoma mansoni Smp_033950 I 0.735
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.922
TC010848 Tribolium castaneum TC010848 I 0.961
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.756
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.892
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.814
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.765
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.951
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.882
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.980
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.882
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.980
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.980
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.961
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.980
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.980
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.980
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.980
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.980
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.961
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.980
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.971
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.980
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.980
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.961
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.922
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.922
AAH84196 Xenopus laevis AAH84196 I 0.980
CLEC002594 Cimex lectularius CLEC002594 I 0.951
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.941
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.951
LCUP007928 Lucilia cuprina LCUP007928 I 0.961
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.961
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.765
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.794
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.980
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.961
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.961
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.980
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.882
AALB009485 Anopheles albimanus AALB009485 I 0.931
AARA004719 Anopheles arabiensis AARA004719 I 0.951
AATE010695 Anopheles atroparvus AATE010695 I 0.951
ACHR000067 Anopheles christyi ACHR000067 I 0.951
ACOM037505 Anopheles coluzzii ACOM037505 I 0.951
ACUA025512 Anopheles culicifacies ACUA025512 I 0.951
ADIR002761 Anopheles dirus ADIR002761 I 0.951
AEPI002385 Anopheles epiroticus AEPI002385 I 0.951
AFAF011208 Anopheles farauti AFAF011208 I 0.951
AFUN009864 Anopheles funestus AFUN009864 I 0.951
AMAM019778 Anopheles maculatus AMAM019778 I 0.951
AMEM015931 Anopheles merus AMEM015931 I 0.951
AMIN000723 Anopheles minimus AMIN000723 I 0.951
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.951
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.951
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.931
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.961
MDOA012885 Musca domestica MDOA012885 I 0.961
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.961
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.804
ASU_13433 Ascaris suum ASU_13433 I 0.775
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.784
D915_03789 Fasciola hepatica D915_03789 I 0.784
D917_09719 Trichinella nativa D917_09719 I 0.814
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.794
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.775
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.794
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.775
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.775
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.775
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.765
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.735
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.725
T265_11013 Opisthorchis viverrini T265_11013 I 0.804
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.765
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.824
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.784
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.824