Ascl2 (Mus musculus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSMUSG00000009248 T035664_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Ascl2
M00117_2.00		 Mus musculus
NVCABVTGBN
NVCABVTGBN		 PBM
Badis et al.(2009)
Ascl2_2654		 (Direct) (Direct)
Ascl2
M02814_2.00		 Mus musculus
RRCAGCTGYY
RRCAGCTGYY		 SELEX
Jolma et al.(2013)
Ascl2_1		 (Direct) (Direct)
Ascl2
M08744_2.00		 Mus musculus
RGCAGSTGB
VCASCTGCY		 Misc
Kulakovskiy et al.(2013)
ASCL2_MOUSE.H11MO.0.C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ASCL2
M04207_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_eDBD_HT-SELEX 		0.914 0.980
ASCL2
M04209_2.00 		Homo sapiens
VCACRACGCD
HGCGTYGTGB		 SELEX
Yin et al.(2017)
ASCL2_FL_HT-SELEX_1 		0.914 0.980
ASCL2
M04210_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_FL_HT-SELEX_2 		0.914 0.980
ASCL2
M04208_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL2_eDBD_Methyl-HT-SELEX 		0.914 0.980
ASCL2
M04211_2.00 		Homo sapiens
VRCAGCTGYB
VRCAGCTGYB		 SELEX
Yin et al.(2017)
ASCL2_FL_Methyl-HT-SELEX 		0.914 0.980
ASCL1
M04135_2.00 		Homo sapiens
NRCASSTGYN
NRCASSTGYN		 SELEX
Yin et al.(2017)
ASCL1_eDBD_HT-SELEX 		0.871 0.880
ASCL1
M08055_2.00 		Homo sapiens
NNRGCAGCTGSNN
NNSCAGCTGCYNN		 ChIP-seq
Mathelier et al.(2014)
MA1100.1 		0.871 0.880
ASCL1
M08730_2.00 		Homo sapiens
NNVCASCTGCYBYN
NRVRGCAGSTGBNN		 Misc
Kulakovskiy et al.(2013)
ASCL1_HUMAN.H11MO.0.A 		0.871 0.880
Ascl1
M08748_2.00 		Mus musculus
BHSCASCTGCYBBN
NVVRGCAGSTGSDV		 Misc
Kulakovskiy et al.(2013)
ASCL1_MOUSE.H11MO.0.A 		0.871 0.880
Ascl1
M09464_2.00 		Mus musculus
NVCABCTGBBNN
NNVVCAGVTGBN		 Misc
Heinz et al.(2010)
NeuralTubes-Ascl1_GSE55840 		0.871 0.880
ASCL1
M09855_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6_01 		0.871 0.880
ASCL1
M09856_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6_02 		0.871 0.880
ASCL1
M09857_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MASH1_Q6 		0.871 0.880
ASCL1
M04136_2.00 		Homo sapiens
NRCAGCTGYN
NRCAGCTGYN		 SELEX
Yin et al.(2017)
ASCL1_eDBD_Methyl-HT-SELEX 		0.871 0.880
For this family, TFs with SR scores > 0.838 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00117_2.00 bHLH 121 171

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000009392 bHLH 121 171
ENSMUSP00000113012 bHLH 53 103

Links

Other bHLH family TFs
Other Mus musculus TFs

72 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
29814.m000741 Ricinus communis 29814.m000741 I
29900.m001628 Ricinus communis 29900.m001628 I
AT3G58630 Arabidopsis thaliana AT3G58630 D
Bo6g075950 Brassica oleracea Bo6g075950 I
Bostr.20903s0103 Boechera stricta Bostr.20903s0103 I
Bra003346 Brassica rapa Bra003346 I
Cagra.0686s0075 Capsella grandiflora Cagra.0686s0075 I
Carubv10017646m.g Capsella rubella Carubv10017646m.g I
cassava21220.m1 Manihot esculenta cassava21220.m1 I
cassava2218.valid.m1 Manihot esculenta cassava2218.valid.m1 I
Ca_00394 Cicer arietinum Ca_00394 I
Ca_19877 Cicer arietinum Ca_19877 I
Ciclev10016016m.g Citrus clementina Ciclev10016016m.g I
Cla009854 Citrullus lanatus Cla009854 I
Cla019967 Citrullus lanatus Cla019967 I
Cucsa.213110 Cucumis sativus Cucsa.213110 I
Cucsa.213120 Cucumis sativus Cucsa.213120 I
evm.TU.supercontig_209.41 Carica papaya evm.TU.supercontig_209.41 I
evm.TU.supercontig_7.72 Carica papaya evm.TU.supercontig_7.72 I
fgenesh2_kg.5__2307__AT3G58630.1 Arabidopsis lyrata fgenesh2_kg.5__2307__AT3G58630.1 I
gene29666-v1.0-hybrid Fragaria vesca gene29666-v1.0-hybrid I
GLYMA13G30280 Glycine max GLYMA13G30280 I
GLYMA13G36650 Glycine max GLYMA13G36650 I
GLYMA15G08890 Glycine max GLYMA15G08890 I
Gorai.011G039600 Gossypium raimondii Gorai.011G039600 I
GSMUA_Achr6G26840_001 Musa acuminata GSMUA_Achr6G26840_001 I
GSMUA_Achr9G04510_001 Musa acuminata GSMUA_Achr9G04510_001 I
GSMUA_Achr9G06410_001 Musa acuminata GSMUA_Achr9G06410_001 I
LjSGA_058481.1 Lotus japonicus LjSGA_058481.1 I
MDP0000301451 Malus domestica MDP0000301451 I
mgf001239m Mimulus guttatus mgf001239m N
MTR_2g016140 Medicago truncatula MTR_2g016140 I
MTR_4g079960 Medicago truncatula MTR_4g079960 I
orange1.1g021525m.g Citrus sinensis orange1.1g021525m.g I
PGSC0003DMG400007806 Solanum tuberosum PGSC0003DMG400007806 I
PGSC0003DMG400010197 Solanum tuberosum PGSC0003DMG400010197 I
PGSC0003DMG400020421 Solanum tuberosum PGSC0003DMG400020421 N
PK27986.1 Cannabis sativa PK27986.1 I
POPTR_0001s08350 Populus trichocarpa POPTR_0001s08350 I
POPTR_0008s07140 Populus trichocarpa POPTR_0008s07140 I
PRUPE_ppa008833mg Prunus persica PRUPE_ppa008833mg I
PRUPE_ppa009171mg Prunus persica PRUPE_ppa009171mg I
SapurV1A.0045s0480 Salix purpurea SapurV1A.0045s0480 I
SapurV1A.0260s0280 Salix purpurea SapurV1A.0260s0280 I
SapurV1A.0650s0110 Salix purpurea SapurV1A.0650s0110 I
Solyc02g076810.2 Solanum lycopersicum Solyc02g076810.2 I
Solyc12g010890.1 Solanum lycopersicum Solyc12g010890.1 I
TCM_029695 Theobroma cacao TCM_029695 I
Thhalv10006105m.g Eutrema salsugineum Thhalv10006105m.g I
VIT_10s0003g01300 Vitis vinifera VIT_10s0003g01300 I
VIT_12s0028g02150 Vitis vinifera VIT_12s0028g02150 I