nhr-49 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00003639 T306163_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-49
M02413_2.00		 Caenorhabditis elegans
NNNNWNHAN
NTDNWNNNN		 PBM
Weirauch et al.(2014)
pTH5891		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-1
M00686_2.00 		Caenorhabditis elegans
ARTGATCA
TGATCAYT		 PBM
Narasimhan et al.(2015)
pTH9322 		0.956 0.614
Hnf4
M03935_2.00 		Drosophila melanogaster
RGGKCAAAGGTCA
TGACCTTTGMCCY		 SELEX
Nitta et al.(2015)
Hnf4_1 		0.832 0.571
Hnf4
M03936_2.00 		Drosophila melanogaster
RGGKCAAAGTYCA
TGRACTTTGMCCY		 SELEX
Nitta et al.(2015)
Hnf4_2 		0.832 0.571
Hnf4
M03937_2.00 		Drosophila melanogaster
RGTVCAAAGKTCR
YGAMCTTTGBACY		 SELEX
Nitta et al.(2015)
Hnf4_3 		0.832 0.571
Hnf4
M03938_2.00 		Drosophila melanogaster
RTGRACTTTGGACY
RGTCCAAAGTYCAY		 SELEX
Nitta et al.(2015)
Hnf4_4 		0.832 0.571
Hnf4
M06428_2.00 		Drosophila melanogaster
DKNKWSSNGGGGTCA
TGACCCCNSSWMNMH		 B1H
Zhu et al.(2011)
Hnf4_SANGER_10_FBgn0004914 		0.832 0.571
Hnf4
M06429_2.00 		Drosophila melanogaster
GGGGTCAH
DTGACCCC		 B1H
Zhu et al.(2011)
Hnf4_SANGER_5_FBgn0004914 		0.832 0.571
Hnf4a
M00182_2.00 		Mus musculus
NNRGKYMRNN
NNYKRMCYNN		 PBM
Badis et al.(2009)
Hnf4a_2640 		0.827 0.557
HNF4A
M03357_2.00 		Homo sapiens
RWTGRACTTTGSACYB
VRGTSCAAAGTYCAWY		 SELEX
Jolma et al.(2013)
HNF4A_1 		0.827 0.557
HNF4A
M03358_2.00 		Homo sapiens
RRGGKCAAAGTCCRBN
NVYGGACTTTGMCCYY		 SELEX
Jolma et al.(2013)
HNF4A_2 		0.827 0.557
HNF4A
M03359_2.00 		Homo sapiens
NDTGGACTTTGDACYB
VRGTHCAAAGTCCAHN		 SELEX
Jolma et al.(2013)
HNF4A_3 		0.827 0.557
HNF4A
M03360_2.00 		Homo sapiens
RRGGTCAAAGKTCA
TGAMCTTTGACCYY		 SELEX
Jolma et al.(2013)
HNF4A_4 		0.827 0.557
HNF4A
M03361_2.00 		Homo sapiens
VRGGTCAAAGTCCANN
NNTGGACTTTGACCYB		 SELEX
Jolma et al.(2013)
HNF4A_5 		0.827 0.557
HNF4A
M03362_2.00 		Homo sapiens
RRGTYCAAAGKTCAH
DTGAMCTTTGRACYY		 SELEX
Jolma et al.(2013)
HNF4A_6 		0.827 0.557
Hnf4a
M03426_2.00 		Mus musculus
RRGGTCAAAGTCCANN
NNTGGACTTTGACCYY		 SELEX
Jolma et al.(2013)
Hnf4a_1 		0.827 0.557
HNF4A
M05573_2.00 		Homo sapiens
RRGGTCAAAGGTCRN
NYGACCTTTGACCYY		 SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_1 		0.827 0.557
HNF4A
M05574_2.00 		Homo sapiens
RRGGTCAAAGTCCAH
DTGGACTTTGACCYY		 SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_2 		0.827 0.557
HNF4A
M05575_2.00 		Homo sapiens
RRGTCCAAAGGTCRN
NYGACCTTTGGACYY		 SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_3 		0.827 0.557
HNF4A
M05576_2.00 		Homo sapiens
DTGGACTTTGGACYY
RRGTCCAAAGTCCAH		 SELEX
Yin et al.(2017)
HNF4A_eDBD_HT-SELEX_4 		0.827 0.557
HNF4A
M08219_2.00 		Homo sapiens
VRGDBCAAAGKYCAN
NTGRMCTTTGVHCYB		 ChIP-seq
Contrino et al.(2012)
Mv81 		0.827 0.557
HNF4A
M08220_2.00 		Homo sapiens
AGTCCA
TGGACT		 ChIP-seq
Contrino et al.(2012)
Mv82 		0.827 0.557
HNF4A
M09268_2.00 		Homo sapiens
VRGKNCAAAGTYCA
TGRACTTTGNMCYB		 Misc
Kulakovskiy et al.(2013)
HNF4A_HUMAN.H11MO.0.A 		0.827 0.557
Hnf4a
M09308_2.00 		Mus musculus
NRGKBCAAAGTYCA
TGRACTTTGVMCYN		 Misc
Kulakovskiy et al.(2013)
HNF4A_MOUSE.H11MO.0.A 		0.827 0.557
HNF4A
M09605_2.00 		Homo sapiens
NNVRGDNCAAAGKYCA
TGRMCTTTGNHCYBNN		 Misc
Heinz et al.(2010)
HepG2-HNF4a_GSE25021 		0.827 0.557
HNF4A
M11105_2.00 		Homo sapiens
VRGGNCAAAGKYCRB
VYGRMCTTTGNCCYB		 Transfac
Matys et al.(2006)
V$HNF4_01_B 		0.827 0.557
HNF4A
M11106_2.00 		Homo sapiens
NNNRGDBYAAAGKBCANND
HNNTGVMCTTTRVHCYNNN		 Transfac
Matys et al.(2006)
V$HNF4_01 		0.827 0.557
HNF4A
M11107_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4A_09 		0.827 0.557
HNF4A
M11108_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4A_10 		0.827 0.557
HNF4A
M11109_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4ALPHA_Q6 		0.827 0.557
HNF4A
M11110_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4A_Q3 		0.827 0.557
HNF4A
M11111_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4A_Q6_01 		0.827 0.557
HNF4A
M11112_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4_Q6_01 		0.827 0.557
HNF4A
M11113_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4_Q6_02 		0.827 0.557
HNF4A
M11114_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4_Q6_03 		0.827 0.557
HNF4A
M11115_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4_Q6_04 		0.827 0.557
HNF4A
M05577_2.00 		Homo sapiens
RRGGTCAAAGGTCRN
NYGACCTTTGACCYY		 SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_1 		0.827 0.557
HNF4A
M05578_2.00 		Homo sapiens
RRGGTCAAAGTCCRN
NYGGACTTTGACCYY		 SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_2 		0.827 0.557
HNF4A
M05579_2.00 		Homo sapiens
RRGTCCAAAGGTCRN
NYGACCTTTGGACYY		 SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_3 		0.827 0.557
HNF4A
M05580_2.00 		Homo sapiens
DTGGACTTTGGACYY
RRGTCCAAAGTCCAH		 SELEX
Yin et al.(2017)
HNF4A_eDBD_Methyl-HT-SELEX_4 		0.827 0.557
HNF4G
M08155_2.00 		Homo sapiens
NVRGDNCAAAGKYCA
TGRMCTTTGNHCYBN		 ChIP-seq
Mathelier et al.(2014)
MA0484.1 		0.824 0.543
HNF4G
M09287_2.00 		Homo sapiens
VRGDNCAAAGKYCA
TGRMCTTTGNHCYB		 Misc
Kulakovskiy et al.(2013)
HNF4G_HUMAN.H11MO.0.B 		0.824 0.543
Hnf4g
M09307_2.00 		Mus musculus
VRGDNCAAAGKYCA
TGRMCTTTGNHCYB		 Misc
Kulakovskiy et al.(2013)
HNF4G_MOUSE.H11MO.0.C 		0.824 0.543
HNF4G
M11155_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4G_01 		0.824 0.543
HNF4G
M11156_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$HNF4G_02 		0.824 0.543
For this family, TFs with SR scores > 0.745 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02413_2.00 Nuclear receptor 1 70

DNA Binding Domains

Protein ID Domain From To Sequence
K10C3.6a.1 Nuclear receptor 9 78
K10C3.6a.2 Nuclear receptor 9 78
K10C3.6a.3 Nuclear receptor 9 78
K10C3.6b.1 Nuclear receptor 9 78
K10C3.6b.2 Nuclear receptor 9 78
K10C3.6c.1 Nuclear receptor 33 102
K10C3.6c.2 Nuclear receptor 33 102
K10C3.6d.1 Nuclear receptor 18 87
K10C3.6d.2 Nuclear receptor 18 87

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

545 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
30174.m008784 Ricinus communis 30174.m008784 N
AMTR_s00111p00072510 Amborella trichopoda AMTR_s00111p00072510 N
Aquca_002_00029 Aquilegia coerulea Aquca_002_00029 N
Aquca_081_00025 Aquilegia coerulea Aquca_081_00025 N
BGIOSGA016880 Oryza indica BGIOSGA016880 N
Bo6g077030 Brassica oleracea Bo6g077030 N
Bo8g095200 Brassica oleracea Bo8g095200 N
Bostr.13158s0042 Boechera stricta Bostr.13158s0042 N
Bostr.13158s0046 Boechera stricta Bostr.13158s0046 N
Bra003413 Brassica rapa Bra003413 N
Bra007536 Brassica rapa Bra007536 N
BRADI5G17600 Brachypodium distachyon BRADI5G17600 N
Cagra.3527s0008 Capsella grandiflora Cagra.3527s0008 N
Carubv10019483m.g Capsella rubella Carubv10019483m.g N
cassava17368.m1 Manihot esculenta cassava17368.m1 N
cassava19913.m1 Manihot esculenta cassava19913.m1 N
Ca_18954 Cicer arietinum Ca_18954 N
Ca_19557 Cicer arietinum Ca_19557 N
Ciclev10021345m.g Citrus clementina Ciclev10021345m.g N
Cla006831 Citrullus lanatus Cla006831 N
Cla010897 Citrullus lanatus Cla010897 N
Cucsa.094180 Cucumis sativus Cucsa.094180 N
Cucsa.121070 Cucumis sativus Cucsa.121070 N
DUO1 Vitis vinifera VIT_15s0021g02040 N
DUO1 Arabidopsis thaliana AT3G60460 N
DUO1 Arabidopsis lyrata fgenesh2_kg.5__2511__AT3G60460.1 N
Eucgr.E01581 Eucalyptus grandis Eucgr.E01581 N
evm.TU.supercontig_37.96 Carica papaya evm.TU.supercontig_37.96 N
gene04800-v1.0-hybrid Fragaria vesca gene04800-v1.0-hybrid N
gene12261-v1.0-hybrid Fragaria vesca gene12261-v1.0-hybrid N
GLYMA03G26830 Glycine max GLYMA03G26830 N
GLYMA07G14480 Glycine max GLYMA07G14480 N
GLYMA09G00371 Glycine max GLYMA09G00371 N
GLYMA12G37026 Glycine max GLYMA12G37026 N
Gorai.003G112700 Gossypium raimondii Gorai.003G112700 N
Gorai.004G165400 Gossypium raimondii Gorai.004G165400 N
GRMZM2G046443 Zea mays GRMZM2G046443 N
GRMZM2G105137 Zea mays GRMZM2G105137 N
GRMZM2G311059 Zea mays GRMZM2G311059 N
GSMUA_Achr1G01660_001 Musa acuminata GSMUA_Achr1G01660_001 N
LjT36B17.50.nd Lotus japonicus LjT36B17.50.nd N
LPERR04G16870 Leersia perrieri LPERR04G16870 N
Lus10009780.g Linum usitatissimum Lus10009780.g N
MDP0000237596 Malus domestica MDP0000237596 N
MDP0000319634 Malus domestica MDP0000319634 N
mgf004314m Mimulus guttatus mgf004314m N
MTR_4g029540 Medicago truncatula MTR_4g029540 N
MTR_8g006470 Medicago truncatula MTR_8g006470 N
OB04G27810 Oryza brachyantha OB04G27810 N
OBART04G20790 Oryza barthii OBART04G20790 N
OGLUM04G20730 Oryza glumaepatula OGLUM04G20730 N
OMERI04G17240 Oryza meridionalis OMERI04G17240 N
ONIVA04G19030 Oryza nivara ONIVA04G19030 N
OPUNC04G18480 Oryza punctata OPUNC04G18480 N
orange1.1g038795m.g Citrus sinensis orange1.1g038795m.g N
ORGLA04G0178400 Oryza glaberrima ORGLA04G0178400 N
ORUFI04G22380 Oryza rufipogon ORUFI04G22380 N
Pavir.Fa00479 Panicum virgatum Pavir.Fa00479 N
Pavir.Fb01900 Panicum virgatum Pavir.Fb01900 N
Pavir.Gb01130 Panicum virgatum Pavir.Gb01130 N
Pavir.J30013 Panicum virgatum Pavir.J30013 N
Pavir.J35399 Panicum virgatum Pavir.J35399 N
PGSC0003DMG400025720 Solanum tuberosum PGSC0003DMG400025720 N
Pm017596 Prunus mume Pm017596 N
Pm019530 Prunus mume Pm019530 N
Pm031387 Prunus mume Pm031387 N
POPTR_0002s14180 Populus trichocarpa POPTR_0002s14180 N
POPTR_0014s05370 Populus trichocarpa POPTR_0014s05370 N
POPTR_0014s05420 Populus trichocarpa POPTR_0014s05420 N
PRUPE_ppa016603mg Prunus persica PRUPE_ppa016603mg N
PRUPE_ppa020326mg Prunus persica PRUPE_ppa020326mg N
SapurV1A.0033s0200 Salix purpurea SapurV1A.0033s0200 N
SapurV1A.0490s0170 Salix purpurea SapurV1A.0490s0170 N
Sb06g024510 Sorghum bicolor Sb06g024510 N
Sb07g027160 Sorghum bicolor Sb07g027160 N
SELMODRAFT_116971 Selaginella moellendorffii SELMODRAFT_116971 N
SELMODRAFT_118852 Selaginella moellendorffii SELMODRAFT_118852 N
Si012032m.g Setaria italica Si012032m.g N
Si015815m.g Setaria italica Si015815m.g N
Solyc01g090530.1 Solanum lycopersicum Solyc01g090530.1 N
Solyc10g019260.1 Solanum lycopersicum Solyc10g019260.1 N
TCM_005653 Theobroma cacao TCM_005653 N
TCM_014872 Theobroma cacao TCM_014872 N
Thhalv10006475m.g Eutrema salsugineum Thhalv10006475m.g N
Traes_2AL_0A21FB42C Triticum aestivum Traes_2AL_0A21FB42C N
Traes_2BL_855A1170C Triticum aestivum Traes_2BL_855A1170C N
Traes_2DL_912473A86 Triticum aestivum Traes_2DL_912473A86 N