ENSP00000347463 (Macaca fascicularis)
EBF1

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF16422 (COE1_DBD) (none) ENSP00000347463 T174812_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
EBF3
M10461_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EBF_Q6 		0.993 0.993
Ebf1
M09045_2.00 		Mus musculus
DBYCCCWRGGGAV
BTCCCYWGGGRVH		 Misc
Kulakovskiy et al.(2013)
COE1_MOUSE.H11MO.0.A 		0.960 0.960
Ebf1
M09527_2.00 		Mus musculus
DBTCCCHDGGGA
TCCCHDGGGAVH		 Misc
Heinz et al.(2010)
proBcell-EBF_GSE21978 		0.960 0.960
Ebf1
M10469_2.00 		Mus musculus
VYMHVYYCYYBRGGGAVTHKHB
VDMDABTCCCYVRRGRRBDKRB		 Transfac
Matys et al.(2006)
V$OLF1_01 		0.960 0.960
Ebf2
M10467_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$COE2_01 		0.921 0.921
Ebf4
M10468_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EBF4_01 		0.921 0.921
EBF4
M10460_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EBF4_02 		0.921 0.921
kn
M03721_2.00 		Drosophila melanogaster
BWATTCCCHDGGGAATWV
BWATTCCCHDGGGAATWV		 SELEX
Nitta et al.(2015)
kn_1 		0.854 0.854
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000347463 EBF1 1 151

Links

Other EBF1 family TFs
Other Macaca fascicularis TFs

247 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Alligator_sinensis_CCG000393.1 Alligator sinensis Alligator_sinensis_CCG000393.1 I 1.000
Myotis_brandtii_Ebf1_10034833 Myotis brandtii Myotis_brandtii_Ebf1_10034833 I 1.000
EBF1 Meleagris gallopavo ENSMGAG00000004896 I 1.000
Pvit_12046 Pogona vitticeps Pvit_12046 I 1.000
EBF3 Dasypus novemcinctus ENSDNOG00000002588 I 1.000
EBF1 Equus caballus ENSECAG00000007964 I 1.000
ENSAPLG00000015476 Anas platyrhynchos ENSAPLG00000015476 I 1.000
ENSPANG00000010656 Papio anubis ENSPANG00000010656 I 1.000
ENSSSCG00000010757 Sus scrofa ENSSSCG00000010757 I 0.993
EBF3 Cavia porcellus ENSCPOG00000005096 I 0.993
EBF3 Callithrix jacchus ENSCJAG00000014357 I 0.993
EBF3 Taeniopygia guttata ENSTGUG00000011600 I 0.993
ENSSTOG00000006113 Ictidomys tridecemlineatus ENSSTOG00000006113 I 0.993
ENSPSIG00000016691 Pelodiscus sinensis ENSPSIG00000016691 I 0.993
EBF3 Macaca mulatta ENSMMUG00000011447 I 0.993
Ebf3 Mus musculus ENSMUSG00000010476 I 0.993
EBF3 Otolemur garnettii ENSOGAG00000007572 I 0.993
EBF3 Microcebus murinus ENSMICG00000008536 I 0.993
ENSPPYG00000002766 Pongo abelii ENSPPYG00000002766 I 0.993
EBF3 Homo sapiens ENSG00000108001 D 0.993
EBF3 Tursiops truncatus ENSTTRG00000014010 I 0.993
ENSFALG00000001212 Ficedula albicollis ENSFALG00000001212 I 0.993
Ebf3 Rattus norvegicus ENSRNOG00000016102 I 0.993
ENSP00000347463-D1 Bos grunniens ENSP00000347463-D1 I 0.993
EBF3 Anolis carolinensis ENSACAG00000008590 I 0.993
Aan_R007097 Calypte anna Aan_R007097 I 0.993
Cmyd_10020950 Chelonia mydas Cmyd_10020950 I 0.993
ENSLOCG00000007615 Lepisosteus oculatus ENSLOCG00000007615 I 0.987
ebf3a Danio rerio ENSDARG00000100244 I 0.980
ebf3 Xenopus tropicalis XB-GENE-962543 I 0.980
ebf3a Oryzias latipes ENSORLG00000005870 I 0.974
ENSAMXG00000006585 Astyanax mexicanus ENSAMXG00000006585 I 0.974
EBF4 Oryzias latipes ENSORLG00000020414 I 0.974
ENSONIG00000019141 Oreochromis niloticus ENSONIG00000019141 I 0.974
ENSGMOG00000016636 Gadus morhua ENSGMOG00000016636 I 0.974
ENSPFOG00000002559 Poecilia formosa ENSPFOG00000002559 I 0.974
ENSXMAG00000012715 Xiphophorus maculatus ENSXMAG00000012715 I 0.974
ENSPFOG00000017183 Poecilia formosa ENSPFOG00000017183 I 0.974
ENSXMAG00000006633 Xiphophorus maculatus ENSXMAG00000006633 I 0.974
ENSONIG00000000451 Oreochromis niloticus ENSONIG00000000451 I 0.974
ebf3a Gasterosteus aculeatus ENSGACG00000009548 I 0.967
ebf3a Takifugu rubripes ENSTRUG00000005721 I 0.967
EBF1 Gorilla gorilla ENSGGOG00000000033 I 0.960
EBF1 Microcebus murinus ENSMICG00000010036 I 0.960
EBF1 Monodelphis domestica ENSMODG00000008198 I 0.960
EBF1 Pan troglodytes ENSPTRG00000017477 I 0.960
ENSPPYG00000015995 Pongo abelii ENSPPYG00000015995 I 0.960
ENSGACG00000010053 Gasterosteus aculeatus ENSGACG00000010053 I 0.960
EBF1 Homo sapiens ENSG00000164330 D 0.960
Ebf1 Rattus norvegicus ENSRNOG00000028845 I 0.960
EBF1 Ornithorhynchus anatinus ENSOANG00000012338 I 0.960
EBF1 Callithrix jacchus ENSCJAG00000019016 I 0.960
EBF1 Bos taurus ENSBTAG00000037508 I 0.960
Ebf1 Mus musculus ENSMUSG00000057098 D 0.960
EBF1 Tupaia belangeri ENSTBEG00000007800 I 0.960
EBF1 Echinops telfairi ENSETEG00000011711 I 0.960
ENSAMEG00000006442 Ailuropoda melanoleuca ENSAMEG00000006442 I 0.954
ENSONIG00000004376 Oreochromis niloticus ENSONIG00000004376 I 0.954
EBF1 Loxodonta africana ENSLAFG00000017522 I 0.954
Pvit_16838 Pogona vitticeps Pvit_16838 I 0.954
ENSXMAG00000010668 Xiphophorus maculatus ENSXMAG00000010668 I 0.954
ENSLOCG00000001693 Lepisosteus oculatus ENSLOCG00000001693 I 0.954
ENSLOCG00000009282 Lepisosteus oculatus ENSLOCG00000009282 I 0.954
Sakowv30011033m.g Saccoglossus kowalevskii Sakowv30011033m.g I 0.952
ENSONIG00000017655 Oreochromis niloticus ENSONIG00000017655 I 0.947
ENSPFOG00000000294 Poecilia formosa ENSPFOG00000000294 I 0.947
EBF1 Oryzias latipes ENSORLG00000007471 I 0.947
EBF1 Oryctolagus cuniculus ENSOCUG00000008985 I 0.940
EBF1 Canis familiaris ENSCAFG00000017318 I 0.940
EBF1 Takifugu rubripes ENSTRUG00000009320 I 0.940
EBF4 Monodelphis domestica ENSMODG00000005256 I 0.940
ebf1a Danio rerio ENSDARG00000099849 I 0.940
ebf4 Xenopus tropicalis XB-GENE-6030626 I 0.940
EBF1 Cavia porcellus ENSCPOG00000026184 I 0.940
ENSAMXG00000003402 Astyanax mexicanus ENSAMXG00000003402 I 0.940
EBF1 Gasterosteus aculeatus ENSGACG00000018450 I 0.940
EBF1 Felis catus ENSFCAG00000008547 I 0.940
ENSSHAG00000017239 Sarcophilus harrisii ENSSHAG00000017239 I 0.940
ENSPFOG00000007531 Poecilia formosa ENSPFOG00000007531 I 0.934
EBF1 Oryzias latipes ENSORLG00000002342 I 0.934
EBF1 Gasterosteus aculeatus ENSGACG00000020458 I 0.934
ENSXMAG00000000489 Xiphophorus maculatus ENSXMAG00000000489 I 0.934
ENSGMOG00000015541 Gadus morhua ENSGMOG00000015541 I 0.934
ENSONIG00000008631 Oreochromis niloticus ENSONIG00000008631 I 0.927
ebf1b Danio rerio ENSDARG00000069196 I 0.927
ENSAMEG00000011229 Ailuropoda melanoleuca ENSAMEG00000011229 I 0.927
EBF1 Taeniopygia guttata ENSTGUG00000000593 I 0.921
EBF4 Ochotona princeps ENSOPRG00000013703 I 0.921
Afo_R003215 Aptenodytes forsteri Afo_R003215 I 0.921
ENSTSYG00000019489 Tarsius syrichta ENSTSYG00000019489 I 0.921
EBF2 Otolemur garnettii ENSOGAG00000010783 I 0.921
EBF2 Sus scrofa ENSSSCG00000009655 I 0.921
EBF2 Taeniopygia guttata ENSTGUG00000004267 I 0.921
EBF4 Otolemur garnettii ENSOGAG00000004688 I 0.921
ENSBTAP00000042518-D1 Bos grunniens ENSBTAP00000042518-D1 I 0.921
ENSPPYG00000018454 Pongo abelii ENSPPYG00000018454 I 0.921
ENSPPYG00000010836 Pongo abelii ENSPPYG00000010836 I 0.921
ENSP00000405003 Macaca fascicularis ENSP00000405003 I 0.921
EBF2 Pan troglodytes ENSPTRG00000003058 I 0.921
EBF4 Pteropus vampyrus ENSPVAG00000006830 I 0.921
Myotis_brandtii_EBF4_10032372 Myotis brandtii Myotis_brandtii_EBF4_10032372 I 0.921
Ebf2 Rattus norvegicus ENSRNOG00000011548 I 0.921
Ebf4 Rattus norvegicus ENSRNOG00000007408 I 0.921
EBF2 Pteropus vampyrus ENSPVAG00000024254 I 0.921
EBF4 Sus scrofa ENSSSCG00000007171 I 0.921
ENSPANG00000020231 Papio anubis ENSPANG00000020231 I 0.921
EBF2 Gallus gallus ENSGALG00000000242 I 0.921
EBF2 Homo sapiens ENSG00000221818 D 0.921
ENSFALG00000011234 Ficedula albicollis ENSFALG00000011234 I 0.921
EBF2 Gorilla gorilla ENSGGOG00000001585 I 0.921
EBF4 Gorilla gorilla ENSGGOG00000015503 I 0.921
EBF2 Myotis lucifugus ENSMLUG00000011509 I 0.921
EBF2 Meleagris gallopavo ENSMGAG00000000791 I 0.921
EBF2 Loxodonta africana ENSLAFG00000022465 I 0.921
ENSAMEG00000000326 Ailuropoda melanoleuca ENSAMEG00000000326 I 0.921
EBF2 Dasypus novemcinctus ENSDNOG00000040488 I 0.921
EBF4 Canis familiaris ENSCAFG00000006631 I 0.921
EBF2 Bos taurus ENSBTAG00000040390 I 0.921
EBF4 Bos taurus ENSBTAG00000037757 I 0.921
EBF2 Canis familiaris ENSCAFG00000008918 I 0.921
EBF2 Cavia porcellus ENSCPOG00000001463 I 0.921
ENSCSAG00000010974 Chlorocebus sabaeus ENSCSAG00000010974 I 0.921
ENSAPLG00000009260 Anas platyrhynchos ENSAPLG00000009260 I 0.921
EBF4 Cavia porcellus ENSCPOG00000004862 I 0.921
EBF4 Myotis lucifugus ENSMLUG00000023832 I 0.921
EBF4 Homo sapiens ENSG00000088881 D 0.921
Ebf2 Mus musculus ENSMUSG00000022053 D 0.921
ENSOARG00000005967 Ovis aries ENSOARG00000005967 I 0.921
ENSOARG00000009825 Ovis aries ENSOARG00000009825 I 0.921
Ebf4 Mus musculus ENSMUSG00000053552 D 0.921
EBF4 Macaca mulatta ENSMMUG00000021331 I 0.921
ENSNLEG00000016189 Nomascus leucogenys ENSNLEG00000016189 I 0.921
ENSNLEG00000009110 Nomascus leucogenys ENSNLEG00000009110 I 0.921
ENSMPUG00000009093 Mustela putorius furo ENSMPUG00000009093 I 0.921
EBF2 Oryctolagus cuniculus ENSOCUG00000011972 I 0.921
ENSMPUG00000003195 Mustela putorius furo ENSMPUG00000003195 I 0.921
ebf2 Xenopus tropicalis XB-GENE-971136 I 0.914
EBF4 Tursiops truncatus ENSTTRG00000003459 I 0.914
ebf2.L Xenopus laevis XB-GENE-6252857 I 0.914
ENSPSIG00000016837 Pelodiscus sinensis ENSPSIG00000016837 I 0.914
SPU_004702 Strongylocentrotus purpuratus SPU_004702 I 0.914
ENSLACG00000017271 Latimeria chalumnae ENSLACG00000017271 I 0.907
EBF2 Callithrix jacchus ENSCJAG00000019921 I 0.907
ebf2.S Xenopus laevis XB-GENE-971141 I 0.907
ENSLOCG00000015225 Lepisosteus oculatus ENSLOCG00000015225 I 0.901
ENSPANG00000020188 Papio anubis ENSPANG00000020188 I 0.901
ebf2 Gasterosteus aculeatus ENSGACG00000008451 I 0.894
ebf2 Tetraodon nigroviridis ENSTNIG00000015845 I 0.894
ENSPFOG00000009617 Poecilia formosa ENSPFOG00000009617 I 0.894
ebf2 Takifugu rubripes ENSTRUG00000011528 I 0.894
ENSXMAG00000017859 Xiphophorus maculatus ENSXMAG00000017859 I 0.894
EBF3 Tupaia belangeri ENSTBEG00000005858 I 0.888
ebf2 Oryzias latipes ENSORLG00000006408 I 0.887
ENSCING00000003209 Ciona intestinalis ENSCING00000003209 I 0.881
ENSCSAVG00000000458 Ciona savignyi ENSCSAVG00000000458 I 0.881
ebf3b Danio rerio ENSDARG00000091287 I 0.881
NV10306 Nasonia vitripennis NV10306 I 0.874
L798_15574 Zootermopsis nevadensis L798_15574 I 0.874
TC001270 Tribolium castaneum TC001270 I 0.874
EBF4 Callithrix jacchus ENSCJAG00000021027 I 0.874
TTRE_0000372001 Trichuris trichiura TTRE_0000372001 I 0.868
AGAP011437 Anopheles gambiae AGAP011437 I 0.868
CGI_10023990 Crassostrea gigas CGI_10023990 I 0.868
CapteG93575 Capitella teleta CapteG93575 I 0.868
PHUM119360 Pediculus humanus PHUM119360 I 0.868
ebf2 Danio rerio ENSDARG00000042525 I 0.868
GB42304 Apis mellifera GB42304 I 0.861
KGM_09934 Danaus plexippus KGM_09934 I 0.861
D917_06660 Trichinella nativa D917_06660 I 0.861
EFV50386 Trichinella spiralis EFV50386 I 0.861
GE12286 Drosophila yakuba FBgn0230042 I 0.854
GA24435 Drosophila pseudoobscura FBgn0245832 I 0.854
GM20182 Drosophila sechellia FBgn0175065 I 0.854
nRc.2.0.1.g06532 Romanomermis culicivorax nRc.2.0.1.g06532 I 0.854
GK23295 Drosophila willistoni FBgn0225257 I 0.854
kn Drosophila melanogaster FBgn0001319 D 0.854
GG22397 Drosophila erecta FBgn0114569 I 0.854
ENSNLEG00000001518 Nomascus leucogenys ENSNLEG00000001518 I 0.854
GL10656 Drosophila persimilis FBgn0148266 I 0.854
GF11778 Drosophila ananassae FBgn0088818 I 0.848
DAPPUDRAFT_22285 Daphnia pulex DAPPUDRAFT_22285 I 0.848
LotgiG225788 Lottia gigantea LotgiG225788 I 0.848
MDOA011385 Musca domestica MDOA011385 I 0.848
GJ21945 Drosophila virilis FBgn0209060 I 0.848
GH20479 Drosophila grimshawi FBgn0127942 I 0.848
Alligator_sinensis_CCG006299.1 Alligator sinensis Alligator_sinensis_CCG006299.1 I 0.848
SMU15024001 Schmidtea mediterranea SMU15024001 I 0.841
L893_g31120 Steinernema glaseri L893_g31120 I 0.841
Afo_R002906 Aptenodytes forsteri Afo_R002906 I 0.841
L898_g8304 Steinernema monticolum L898_g8304 I 0.834
EBF4 Felis catus ENSFCAG00000014453 I 0.834
GI21022 Drosophila mojavensis FBgn0143754 I 0.834
EBF4 Dasypus novemcinctus ENSDNOG00000049548 I 0.834
L889_g1820 Steinernema feltiae L889_g1820 I 0.834
EBF1 Tetraodon nigroviridis ENSTNIG00000016148 I 0.834
L596_g20342 Steinernema carpocapsae L596_g20342 I 0.828
PTRK_0001642500 Parastrongyloides trichosuri PTRK_0001642500 I 0.828
HelroG112029 Helobdella robusta HelroG112029 I 0.828
nLs.2.1.2.g08363 Litomosoides sigmodontis nLs.2.1.2.g08363 I 0.821
nAv.1.0.1.g03521 Acanthocheilonema viteae nAv.1.0.1.g03521 I 0.821
Bm6296 Brugia malayi Bm6296 I 0.815
ENSNLEG00000004218 Nomascus leucogenys ENSNLEG00000004218 I 0.815
DME_0000265301 Dracunculus medinensis DME_0000265301 I 0.815
EBF1 Tursiops truncatus ENSTTRG00000009929 I 0.815
nDi.2.2.2.g04990 Dirofilaria immitis nDi.2.2.2.g04990 I 0.815
LOAG_18199 Loa loa LOAG_18199 I 0.815
SVE_0119400 Strongyloides venezuelensis SVE_0119400 I 0.808
SSTP_0000472000 Strongyloides stercoralis SSTP_0000472000 I 0.808
BXY_1639700 Bursaphelenchus xylophilus BXY_1639700 I 0.808
SPAL_0001132500 Strongyloides papillosus SPAL_0001132500 I 0.808
EBF2 Monodelphis domestica ENSMODG00000016702 I 0.808
WUBG_00630 Wuchereria bancrofti WUBG_00630 I 0.808
EBF2 Felis catus ENSFCAG00000003607 I 0.808
MCOS_0000276101 Mesocestoides corti MCOS_0000276101 I 0.801
CBN13270 Caenorhabditis brenneri CBN13270 I 0.801
ENSBTAP00000053340-D3 Bos grunniens ENSBTAP00000053340-D3 I 0.795
SVUK_0001114801 Strongylus vulgaris SVUK_0001114801 I 0.795
CRE15310 Caenorhabditis remanei CRE15310 I 0.795
NECAME_10162 Necator americanus NECAME_10162 I 0.795
HCOI01630600 Haemonchus contortus HCOI01630600 I 0.795
HPLM_0000807901 Haemonchus placei HPLM_0000807901 I 0.795
EBF4 Oryctolagus cuniculus ENSOCUG00000023917 I 0.788
RSKR_0000832900 Rhabditophanes kr3021 RSKR_0000832900 I 0.788
CBG07590 Caenorhabditis briggsae CBG07590 I 0.788
DICVIV_13258 Dictyocaulus viviparus DICVIV_13258 I 0.788
ENSTSYG00000007975 Tarsius syrichta ENSTSYG00000007975 I 0.781
HDID_0000285701 Hymenolepis diminuta HDID_0000285701 I 0.781
TCLT_0000613901 Thelazia callipaeda TCLT_0000613901 I 0.781
HNAJ_0001308901 Hymenolepis nana HNAJ_0001308901 I 0.779
TTAC_0000009401 Hydatigera taeniaeformis TTAC_0000009401 I 0.775
ECANG7_02766 Echinococcus canadensis ECANG7_02766 I 0.775
HmN_000631100 Hymenolepis microstoma HmN_000631100 I 0.775
EBF3 Ornithorhynchus anatinus ENSOANG00000012326 I 0.762
ENSACAG00000007938 Anolis carolinensis ENSACAG00000007938 I 0.762
ENSAMEG00000003291 Ailuropoda melanoleuca ENSAMEG00000003291 I 0.758
T265_13606 Opisthorchis viverrini T265_13606 N 0.755
csin100403 Clonorchis sinensis csin100403 N 0.755
EBF3 Oryctolagus cuniculus ENSOCUG00000008915 I 0.755
EBF3 Echinops telfairi ENSETEG00000014060 I 0.755
ENSCSAG00000004432 Chlorocebus sabaeus ENSCSAG00000004432 I 0.755
GPLIN_000159400 Globodera pallida GPLIN_000159400 I 0.748
HelroG143625 Helobdella robusta HelroG143625 I 0.742
SNAPOd2T00017027001 Oikopleura dioica SNAPOd2T00017027001 I 0.735
EBF3 Gallus gallus ENSGALG00000010461 I 0.735
ENSAPLG00000012647 Anas platyrhynchos ENSAPLG00000012647 I 0.728
NEMVEDRAFT_v1g164975 Nematostella vectensis NEMVEDRAFT_v1g164975 N 0.709
scaffold24-EXSNAP2012.58 Pristionchus exspectatus scaffold24-EXSNAP2012.58 I 0.703