PAX6 (Ornithorhynchus anatinus)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSOANG00000015149 T237416_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.919 0.919
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.919 0.919
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.919 0.919
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.919 0.919
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.919 0.919
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.919 0.919
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.919 0.919
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.919 0.919
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.919 0.919
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.919 0.919
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.919 0.919
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.919 0.919
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.919 0.919
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.919 0.919
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.912 0.912
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.912 0.912
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.912 0.912
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.912 0.912
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.912 0.912
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.912 0.912
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.912 0.912
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.851 0.851
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.851 0.851
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.851 0.851
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.824 0.824
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.824 0.824
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.824 0.824
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSOANP00000023858 Paired box 5 95
ENSOANP00000023858 Homeodomain 175 231

Links

Other Homeodomain,Paired box family TFs
Other Ornithorhynchus anatinus TFs

100 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.986
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.986
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.986
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.986
Aan_R006618 Calypte anna Aan_R006618 I 0.986
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.978
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.961
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.919
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.919
PAX6 Homo sapiens ENSG00000007372 D 0.919
pax6a Danio rerio ENSDARG00000103379 I 0.912
pax6b Danio rerio ENSDARG00000045936 I 0.912
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.912
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.912
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.912
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.905
pax6b Oryzias latipes ENSORLG00000009913 I 0.905
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.905
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.905
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.905
pax6.L Xenopus laevis XB-GENE-865046 I 0.905
pax6.S Xenopus laevis XB-GENE-6464331 I 0.899
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.892
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.892
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.892
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.885
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.878
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.858
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.855
L798_00712 Zootermopsis nevadensis L798_00712 I 0.851
ey Drosophila melanogaster FBgn0005558 D 0.851
TC007409 Tribolium castaneum TC007409 I 0.838
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.838
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.831
GF21877 Drosophila ananassae FBgn0098877 I 0.824
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.812
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.811
fgenesh2_pg.scaffold_23000118 Branchiostoma floridae fgenesh2_pg.scaffold_23000118 I 0.799
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.770
AAEL002321 Aedes aegypti AAEL002321 I 0.770
ACUA021227 Anopheles culicifacies ACUA021227 I 0.757
ISCW006352 Ixodes scapularis ISCW006352 I 0.757
ACUA016154 Anopheles culicifacies ACUA016154 I 0.757
AALB006643 Anopheles albimanus AALB006643 I 0.757
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.747
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.747
PAX6 Sus scrofa ENSSSCG00000013320 I 0.747
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.747
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.747
pax6 Xenopus tropicalis XB-GENE-484088 I 0.747
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.747
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.747
PAX6 Procavia capensis ENSPCAG00000005165 I 0.747
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.747
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.747
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.747
Pax6 Mus musculus ENSMUSG00000027168 D 0.747
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.747
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.747
PAX6 Felis catus ENSFCAG00000007094 I 0.747
PAX6 Microcebus murinus ENSMICG00000004089 I 0.747
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.747
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.747
PAX6 Gallus gallus ENSGALG00000012123 I 0.747
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.747
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.747
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.747
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.747
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.747
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.747
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.747
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.747
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.747
PAX6 Bos taurus ENSBTAG00000004561 I 0.747
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.747
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.747
PAX6 Sorex araneus ENSSARG00000011424 I 0.746
PAX6 Echinops telfairi ENSETEG00000002655 I 0.746
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.743
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.743
Smp_170750 Schistosoma mansoni Smp_170750 I 0.743
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.736
EFV57892 Trichinella spiralis EFV57892 I 0.736
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.736
D915_07175 Fasciola hepatica D915_07175 I 0.736
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.731
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.731
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.731
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.729
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.725
PAX6 Equus caballus ENSECAG00000021000 I 0.725
MCINX016249 Melitaea cinxia MCINX016249 I 0.723
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.719
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.714
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.714
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.714
L798_11483 Zootermopsis nevadensis L798_11483 I 0.713
HelroG173449 Helobdella robusta HelroG173449 I 0.709
SINV20456 Solenopsis invicta SINV20456 I 0.704
SMAR013763 Strigamia maritima SMAR013763 I 0.703