PAX6 (Equus caballus)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSECAG00000021000 T237322_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.967 0.967
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.967 0.967
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.967 0.967
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.967 0.967
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.967 0.967
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.967 0.967
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.967 0.967
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.967 0.967
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.967 0.967
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.967 0.967
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.967 0.967
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.967 0.967
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.967 0.967
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.962 0.962
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.962 0.962
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.962 0.962
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.962 0.962
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.962 0.962
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.962 0.962
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.962 0.962
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.962 0.962
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.912 0.912
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.912 0.912
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.912 0.912
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.885 0.885
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.885 0.885
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.885 0.885
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSECAP00000018871 Paired box 4 142
ENSECAP00000018871 Homeodomain 221 277
ENSECAP00000018876 Paired box 4 128
ENSECAP00000018876 Homeodomain 207 263

Links

Other Homeodomain,Paired box family TFs
Other Equus caballus TFs

227 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
PAX6 Sorex araneus ENSSARG00000011424 I 0.994
PAX6 Echinops telfairi ENSETEG00000002655 I 0.983
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.973
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.973
PAX6 Felis catus ENSFCAG00000007094 I 0.973
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.973
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.973
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.973
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.973
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.973
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.973
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.973
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.973
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.973
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.967
PAX6 Procavia capensis ENSPCAG00000005165 I 0.967
pax6a Danio rerio ENSDARG00000103379 I 0.967
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.967
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.967
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.967
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.967
PAX6 Homo sapiens ENSG00000007372 D 0.967
PAX6 Sus scrofa ENSSSCG00000013320 I 0.967
PAX6 Gallus gallus ENSGALG00000012123 I 0.967
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.967
PAX6 Microcebus murinus ENSMICG00000004089 I 0.967
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.967
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.967
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.967
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.967
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.967
Pax6 Mus musculus ENSMUSG00000027168 D 0.967
PAX6 Bos taurus ENSBTAG00000004561 I 0.967
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.967
pax6 Xenopus tropicalis XB-GENE-484088 I 0.967
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.967
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.967
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.967
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.962
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.962
pax6b Oryzias latipes ENSORLG00000009913 I 0.962
pax6b Danio rerio ENSDARG00000045936 I 0.962
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.962
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.962
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.958
pax6.S Xenopus laevis XB-GENE-6464331 I 0.956
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.956
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.956
pax6.L Xenopus laevis XB-GENE-865046 I 0.956
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.956
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.956
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.956
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.956
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.951
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.951
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.945
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.945
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.934
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.934
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.934
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.934
L798_11483 Zootermopsis nevadensis L798_11483 I 0.928
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.923
SMAR013763 Strigamia maritima SMAR013763 I 0.918
TC008176 Tribolium castaneum TC008176 I 0.918
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.918
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.918
NV15820 Nasonia vitripennis NV15820 I 0.912
GI14081 Drosophila mojavensis FBgn0136835 I 0.912
ey Drosophila melanogaster FBgn0005558 D 0.912
ey Drosophila pseudoobscura FBgn0018538 I 0.912
GF22818 Drosophila ananassae FBgn0099812 I 0.912
GK13702 Drosophila willistoni FBgn0215710 I 0.912
GB50342 Apis mellifera GB50342 I 0.912
ey Drosophila persimilis FBgn0043659 I 0.912
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.912
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.909
ey Drosophila virilis FBgn0028754 I 0.907
L798_00712 Zootermopsis nevadensis L798_00712 I 0.907
ey Drosophila sechellia FBgn0068720 I 0.907
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.907
GE14559 Drosophila yakuba FBgn0232158 I 0.907
GG16399 Drosophila erecta FBgn0108631 I 0.907
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.901
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.901
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.896
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.896
NV17076 Nasonia vitripennis NV17076 I 0.896
GB41504 Apis mellifera GB41504 I 0.896
HelroG80374 Helobdella robusta HelroG80374 I 0.896
TC007409 Tribolium castaneum TC007409 I 0.896
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.890
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.890
GL17563 Drosophila persimilis FBgn0155166 I 0.890
GH23963 Drosophila grimshawi FBgn0131420 I 0.890
GI14042 Drosophila mojavensis FBgn0136796 I 0.890
LotgiG133720 Lottia gigantea LotgiG133720 I 0.890
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.890
ISCW021772 Ixodes scapularis ISCW021772 I 0.890
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.890
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.890
GJ13300 Drosophila virilis FBgn0200526 I 0.890
GK13683 Drosophila willistoni FBgn0215691 I 0.890
GF21877 Drosophila ananassae FBgn0098877 I 0.885
GM13021 Drosophila sechellia FBgn0167952 I 0.885
GE14563 Drosophila yakuba FBgn0232162 I 0.885
GG16402 Drosophila erecta FBgn0108634 I 0.885
toy Drosophila melanogaster FBgn0019650 D 0.885
D918_01592 Trichuris suis D918_01592 I 0.874
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.868
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.868
ISCW006352 Ixodes scapularis ISCW006352 I 0.863
PHUM097050 Pediculus humanus PHUM097050 I 0.863
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.857
AALB006354 Anopheles albimanus AALB006354 I 0.846
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.841
AMIN002127 Anopheles minimus AMIN002127 I 0.841
AARA001115 Anopheles arabiensis AARA001115 I 0.841
ASIS012967 Anopheles sinensis ASIS012967 I 0.841
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.841
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.841
AGAP000063 Anopheles gambiae AGAP000063 I 0.841
L892_g3713 Steinernema scapterisci L892_g3713 I 0.841
ADAC003449 Anopheles darlingi ADAC003449 I 0.836
ASIS012617 Anopheles sinensis ASIS012617 I 0.835
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.835
AFUN011575 Anopheles funestus AFUN011575 I 0.835
AMEC021831 Anopheles melas AMEC021831 I 0.835
CRE07226 Caenorhabditis remanei CRE07226 I 0.830
AAEL002321 Aedes aegypti AAEL002321 I 0.830
T265_09221 Opisthorchis viverrini T265_09221 I 0.830
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.830
AALB006643 Anopheles albimanus AALB006643 I 0.830
ACUA016154 Anopheles culicifacies ACUA016154 I 0.830
ACUA021227 Anopheles culicifacies ACUA021227 I 0.830
AFAF009619 Anopheles farauti AFAF009619 I 0.830
CBN04513 Caenorhabditis brenneri CBN04513 I 0.830
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.826
AEPI005798 Anopheles epiroticus AEPI005798 I 0.824
Smp_160670 Schistosoma mansoni Smp_160670 I 0.824
ADIR000973 Anopheles dirus ADIR000973 I 0.824
AATE014626 Anopheles atroparvus AATE014626 I 0.824
AGAP000067 Anopheles gambiae AGAP000067 I 0.824
AARA001110 Anopheles arabiensis AARA001110 I 0.824
ACHR009845 Anopheles christyi ACHR009845 I 0.824
AEPI005803 Anopheles epiroticus AEPI005803 I 0.824
AMIN002132 Anopheles minimus AMIN002132 I 0.824
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.824
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.824
AFAF017899 Anopheles farauti AFAF017899 I 0.824
AMEM002691 Anopheles merus AMEM002691 I 0.824
AFUN011570 Anopheles funestus AFUN011570 I 0.824
AMEC013051 Anopheles melas AMEC013051 I 0.824
GD24416 Drosophila simulans FBgn0195753 I 0.824
D915_07175 Fasciola hepatica D915_07175 I 0.819
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.819
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.819
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.819
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.813
A_05170 Schistosoma haematobium A_05170 I 0.813
MCINX016249 Melitaea cinxia MCINX016249 I 0.813
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.813
vab-3 Caenorhabditis elegans WBGene00006870 I 0.813
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.813
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.813
EFV57892 Trichinella spiralis EFV57892 I 0.808
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.802
Smp_170750 Schistosoma mansoni Smp_170750 I 0.802
HelroG173449 Helobdella robusta HelroG173449 I 0.802
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.797
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.797
D917_00854 Trichinella nativa D917_00854 I 0.796
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.780
ACHR008920 Anopheles christyi ACHR008920 I 0.775
csin110224 Clonorchis sinensis csin110224 I 0.769
ADIR000968 Anopheles dirus ADIR000968 I 0.765
T265_14971 Opisthorchis viverrini T265_14971 I 0.753
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.753
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.750
ADAC001560 Anopheles darlingi ADAC001560 I 0.747
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.742
MESCA003564 Megaselia scalaris MESCA003564 I 0.736
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.731
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.731
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.731
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.731
TsM_000166900 Taenia solium TsM_000166900 I 0.731
Aan_R006618 Calypte anna Aan_R006618 I 0.731
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.731
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.725
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.720
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.720
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.714
PAX2 Ochotona princeps ENSOPRG00000007096 I 0.705
PAX2 Microcebus murinus ENSMICG00000001357 I 0.705
PAX2 Macaca mulatta ENSMMUG00000009163 I 0.705
ENSPANG00000021132 Papio anubis ENSPANG00000021132 I 0.705
PAX2 Monodelphis domestica ENSMODG00000019353 I 0.705
PAX2 Oryctolagus cuniculus ENSOCUG00000012860 I 0.705
Pax2 Mus musculus ENSMUSG00000004231 D 0.705
PAX2 Gorilla gorilla ENSGGOG00000014908 I 0.705
PAX2 Callithrix jacchus ENSCJAG00000017397 I 0.705
ENSP00000359319 Macaca fascicularis ENSP00000359319 I 0.705
PAX2 Cavia porcellus ENSCPOG00000000939 I 0.705
Myotis_brandtii_PAX2_10025650 Myotis brandtii Myotis_brandtii_PAX2_10025650 I 0.705
PAX2 Dasypus novemcinctus ENSDNOG00000013328 I 0.705
ENSP00000359319-D1 Bos grunniens ENSP00000359319-D1 I 0.705
PAX2 Tursiops truncatus ENSTTRG00000015106 I 0.705
ENSAMEG00000017523 Ailuropoda melanoleuca ENSAMEG00000017523 I 0.705
PAX2 Otolemur garnettii ENSOGAG00000015274 I 0.705
PAX2 Bos taurus ENSBTAG00000021566 I 0.705
PAX2 Canis familiaris ENSCAFG00000009709 I 0.705
PAX2 Equus caballus ENSECAG00000021123 I 0.705
CAA71206 Xenopus laevis CAA71206 I 0.705
PAX2 Pan troglodytes ENSPTRG00000002853 I 0.705
PAX2 Loxodonta africana ENSLAFG00000002388 I 0.705
ENSMEUG00000013247 Macropus eugenii ENSMEUG00000013247 I 0.705
ENSPPYG00000002572 Pongo abelii ENSPPYG00000002572 I 0.705
PAX2 Pteropus vampyrus ENSPVAG00000002148 I 0.705
PAX2 Homo sapiens ENSG00000075891 D 0.705
PAX2 Sus scrofa ENSSSCG00000010556 I 0.705
PAX2 Felis catus ENSFCAG00000011602 I 0.705
PAX2 Procavia capensis ENSPCAG00000006623 I 0.705
ENSSHAG00000014328 Sarcophilus harrisii ENSSHAG00000014328 I 0.705
PAX2 Erinaceus europaeus ENSEEUG00000001995 I 0.705
csin101119 Clonorchis sinensis csin101119 I 0.703