PAX6 (Monodelphis domestica)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSMODG00000009611 T237397_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.967 0.967
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.967 0.967
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.967 0.967
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.967 0.967
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.967 0.967
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.967 0.967
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.967 0.967
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.967 0.967
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.967 0.967
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.967 0.967
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.967 0.967
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.967 0.967
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.967 0.967
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.967 0.967
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.962 0.962
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.962 0.962
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.962 0.962
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.962 0.962
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.962 0.962
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.962 0.962
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.962 0.962
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.901 0.901
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.901 0.901
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.901 0.901
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.874 0.874
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.874 0.874
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.874 0.874
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMODP00000034398 Paired box 4 142
ENSMODP00000034398 Homeodomain 230 286

Links

Other Homeodomain,Paired box family TFs
Other Monodelphis domestica TFs

198 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
PAX6 Sorex araneus ENSSARG00000011424 I 1.000
PAX6 Echinops telfairi ENSETEG00000002655 I 0.988
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.967
PAX6 Microcebus murinus ENSMICG00000004089 I 0.967
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.967
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.967
PAX6 Gallus gallus ENSGALG00000012123 I 0.967
PAX6 Homo sapiens ENSG00000007372 D 0.967
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.967
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.967
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.967
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.967
Pax6 Mus musculus ENSMUSG00000027168 D 0.967
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.967
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.967
PAX6 Sus scrofa ENSSSCG00000013320 I 0.967
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.967
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.967
PAX6 Procavia capensis ENSPCAG00000005165 I 0.967
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.967
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.967
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.967
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.967
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.967
pax6 Xenopus tropicalis XB-GENE-484088 I 0.967
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.967
PAX6 Bos taurus ENSBTAG00000004561 I 0.967
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.962
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.962
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.962
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.962
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.962
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.962
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.962
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.962
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.962
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.962
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.962
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.962
pax6b Danio rerio ENSDARG00000045936 I 0.962
pax6a Danio rerio ENSDARG00000103379 I 0.962
PAX6 Felis catus ENSFCAG00000007094 I 0.962
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.959
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.959
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.958
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.956
pax6b Oryzias latipes ENSORLG00000009913 I 0.956
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.956
pax6.L Xenopus laevis XB-GENE-865046 I 0.956
pax6.S Xenopus laevis XB-GENE-6464331 I 0.956
PAX6 Equus caballus ENSECAG00000021000 I 0.956
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.956
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.951
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.951
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.951
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.945
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.945
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.940
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.940
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.934
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.929
L798_11483 Zootermopsis nevadensis L798_11483 I 0.923
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.923
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.923
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.912
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.912
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.909
SMAR013763 Strigamia maritima SMAR013763 I 0.907
GF22818 Drosophila ananassae FBgn0099812 I 0.907
ey Drosophila persimilis FBgn0043659 I 0.907
TC008176 Tribolium castaneum TC008176 I 0.907
GI14081 Drosophila mojavensis FBgn0136835 I 0.907
ey Drosophila pseudoobscura FBgn0018538 I 0.907
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.907
GK13702 Drosophila willistoni FBgn0215710 I 0.907
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.906
ey Drosophila virilis FBgn0028754 I 0.901
GG16399 Drosophila erecta FBgn0108631 I 0.901
GB50342 Apis mellifera GB50342 I 0.901
GE14559 Drosophila yakuba FBgn0232158 I 0.901
ey Drosophila melanogaster FBgn0005558 D 0.901
ey Drosophila sechellia FBgn0068720 I 0.901
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.901
NV15820 Nasonia vitripennis NV15820 I 0.901
PHUM097050 Pediculus humanus PHUM097050 I 0.901
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.896
L798_00712 Zootermopsis nevadensis L798_00712 I 0.896
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.892
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.890
GB41504 Apis mellifera GB41504 I 0.885
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.885
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.885
HelroG80374 Helobdella robusta HelroG80374 I 0.885
TC007409 Tribolium castaneum TC007409 I 0.885
NV17076 Nasonia vitripennis NV17076 I 0.885
ISCW021772 Ixodes scapularis ISCW021772 I 0.884
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.883
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.879
LotgiG133720 Lottia gigantea LotgiG133720 I 0.879
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.879
GL17563 Drosophila persimilis FBgn0155166 I 0.879
GI14042 Drosophila mojavensis FBgn0136796 I 0.879
GH23963 Drosophila grimshawi FBgn0131420 I 0.879
GK13683 Drosophila willistoni FBgn0215691 I 0.879
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.879
GJ13300 Drosophila virilis FBgn0200526 I 0.879
toy Drosophila melanogaster FBgn0019650 D 0.874
GF21877 Drosophila ananassae FBgn0098877 I 0.874
GG16402 Drosophila erecta FBgn0108634 I 0.874
GM13021 Drosophila sechellia FBgn0167952 I 0.874
GE14563 Drosophila yakuba FBgn0232162 I 0.874
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.868
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.868
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.868
ACHR009845 Anopheles christyi ACHR009845 I 0.866
AATE014626 Anopheles atroparvus AATE014626 I 0.866
ADIR000973 Anopheles dirus ADIR000973 I 0.866
AMIN002132 Anopheles minimus AMIN002132 I 0.866
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.866
AFUN011570 Anopheles funestus AFUN011570 I 0.866
GD24416 Drosophila simulans FBgn0195753 I 0.866
ISCW006352 Ixodes scapularis ISCW006352 I 0.865
D918_01592 Trichuris suis D918_01592 I 0.863
AMEM002691 Anopheles merus AMEM002691 I 0.860
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.860
AMEC013051 Anopheles melas AMEC013051 I 0.860
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.860
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.860
AEPI005798 Anopheles epiroticus AEPI005798 I 0.860
AARA001110 Anopheles arabiensis AARA001110 I 0.860
AGAP000067 Anopheles gambiae AGAP000067 I 0.860
AFAF017899 Anopheles farauti AFAF017899 I 0.860
ADAC001560 Anopheles darlingi ADAC001560 I 0.859
ACUA016154 Anopheles culicifacies ACUA016154 I 0.856
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.846
csin110224 Clonorchis sinensis csin110224 I 0.838
AALB006354 Anopheles albimanus AALB006354 I 0.835
AARA001115 Anopheles arabiensis AARA001115 I 0.830
AMIN002127 Anopheles minimus AMIN002127 I 0.830
AMEC021831 Anopheles melas AMEC021831 I 0.830
AFUN011575 Anopheles funestus AFUN011575 I 0.830
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.830
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.830
L892_g3713 Steinernema scapterisci L892_g3713 I 0.830
ACUA021227 Anopheles culicifacies ACUA021227 I 0.830
ASIS012967 Anopheles sinensis ASIS012967 I 0.830
AGAP000063 Anopheles gambiae AGAP000063 I 0.830
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.830
T265_14971 Opisthorchis viverrini T265_14971 I 0.829
ASIS012617 Anopheles sinensis ASIS012617 I 0.829
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.826
ADAC003449 Anopheles darlingi ADAC003449 I 0.825
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.824
HelroG173449 Helobdella robusta HelroG173449 I 0.824
AEPI005803 Anopheles epiroticus AEPI005803 I 0.824
AAEL002321 Aedes aegypti AAEL002321 I 0.819
T265_09221 Opisthorchis viverrini T265_09221 I 0.819
D915_07175 Fasciola hepatica D915_07175 I 0.819
AFAF009619 Anopheles farauti AFAF009619 I 0.819
EFV57892 Trichinella spiralis EFV57892 I 0.819
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.819
CRE07226 Caenorhabditis remanei CRE07226 I 0.819
AALB006643 Anopheles albimanus AALB006643 I 0.819
CBN04513 Caenorhabditis brenneri CBN04513 I 0.819
ACHR008920 Anopheles christyi ACHR008920 I 0.818
Smp_160670 Schistosoma mansoni Smp_160670 I 0.813
MCINX016249 Melitaea cinxia MCINX016249 I 0.813
A_05170 Schistosoma haematobium A_05170 I 0.813
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.813
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.808
fgenesh2_pg.scaffold_23000118 Branchiostoma floridae fgenesh2_pg.scaffold_23000118 I 0.806
csin101119 Clonorchis sinensis csin101119 I 0.803
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.802
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.802
vab-3 Caenorhabditis elegans WBGene00006870 I 0.802
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.802
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.797
Smp_170750 Schistosoma mansoni Smp_170750 I 0.797
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.797
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.791
D917_00854 Trichinella nativa D917_00854 I 0.785
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.769
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.765
ADIR000968 Anopheles dirus ADIR000968 I 0.760
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.742
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.731
MESCA003564 Megaselia scalaris MESCA003564 I 0.725
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.725
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.725
Aan_R006618 Calypte anna Aan_R006618 I 0.725
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.725
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.720
TsM_000166900 Taenia solium TsM_000166900 I 0.720
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.714
ENSVPAG00000012251 Vicugna pacos ENSVPAG00000012251 I 0.710
PAX7 Choloepus hoffmanni ENSCHOG00000005130 I 0.710
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.709
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.703