HelroG80374 (Helobdella robusta)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		HelroG80374 T237624_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.896 0.896
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.896 0.896
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.896 0.896
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.896 0.896
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.896 0.896
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.896 0.896
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.896 0.896
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.896 0.896
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.896 0.896
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.896 0.896
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.896 0.896
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.896 0.896
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.896 0.896
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.896 0.896
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.890 0.890
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.890 0.890
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.890 0.890
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.890 0.890
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.890 0.890
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.890 0.890
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.890 0.890
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.868 0.868
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.868 0.868
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.868 0.868
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.846 0.846
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.846 0.846
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.846 0.846
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HelroP80374 Paired box 1 125
HelroP80374 Homeodomain 216 272

Links

Other Homeodomain,Paired box family TFs
Other Helobdella robusta TFs

183 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
PAX6 Sorex araneus ENSSARG00000011424 I 0.925
PAX6 Echinops telfairi ENSETEG00000002655 I 0.913
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.901
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.901
pax6b Oryzias latipes ENSORLG00000009913 I 0.901
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.901
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.901
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.901
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.901
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.901
PAX6 Felis catus ENSFCAG00000007094 I 0.901
pax6a Danio rerio ENSDARG00000103379 I 0.901
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.901
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.901
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.901
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.901
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.901
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.901
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.901
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.901
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.896
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.896
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.896
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.896
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.896
PAX6 Microcebus murinus ENSMICG00000004089 I 0.896
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.896
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.896
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.896
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.896
PAX6 Procavia capensis ENSPCAG00000005165 I 0.896
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.896
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.896
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.896
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.896
PAX6 Sus scrofa ENSSSCG00000013320 I 0.896
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.896
Pax6 Mus musculus ENSMUSG00000027168 D 0.896
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.896
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.896
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.896
PAX6 Bos taurus ENSBTAG00000004561 I 0.896
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.896
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.896
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.896
pax6.L Xenopus laevis XB-GENE-865046 I 0.896
pax6.S Xenopus laevis XB-GENE-6464331 I 0.896
pax6 Xenopus tropicalis XB-GENE-484088 I 0.896
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.896
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.896
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.896
PAX6 Equus caballus ENSECAG00000021000 I 0.896
PAX6 Gallus gallus ENSGALG00000012123 I 0.896
PAX6 Homo sapiens ENSG00000007372 D 0.896
pax6b Danio rerio ENSDARG00000045936 I 0.896
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.896
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.890
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.885
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.885
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.885
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.880
LotgiG133720 Lottia gigantea LotgiG133720 I 0.879
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.879
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.879
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.879
ey Drosophila melanogaster FBgn0005558 D 0.868
L798_11483 Zootermopsis nevadensis L798_11483 I 0.867
GK13702 Drosophila willistoni FBgn0215710 I 0.863
ey Drosophila virilis FBgn0028754 I 0.863
GI14081 Drosophila mojavensis FBgn0136835 I 0.863
ey Drosophila persimilis FBgn0043659 I 0.863
ey Drosophila sechellia FBgn0068720 I 0.863
GE14559 Drosophila yakuba FBgn0232158 I 0.863
SMAR013763 Strigamia maritima SMAR013763 I 0.863
GF22818 Drosophila ananassae FBgn0099812 I 0.863
GG16399 Drosophila erecta FBgn0108631 I 0.863
L798_00712 Zootermopsis nevadensis L798_00712 I 0.863
TC008176 Tribolium castaneum TC008176 I 0.863
ey Drosophila pseudoobscura FBgn0018538 I 0.863
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.863
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.863
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.857
NV17076 Nasonia vitripennis NV17076 I 0.852
GK13683 Drosophila willistoni FBgn0215691 I 0.852
NV15820 Nasonia vitripennis NV15820 I 0.852
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.852
GB50342 Apis mellifera GB50342 I 0.852
GB41504 Apis mellifera GB41504 I 0.852
GJ13300 Drosophila virilis FBgn0200526 I 0.852
TC007409 Tribolium castaneum TC007409 I 0.852
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.852
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.852
GI14042 Drosophila mojavensis FBgn0136796 I 0.852
GH23963 Drosophila grimshawi FBgn0131420 I 0.852
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.852
GL17563 Drosophila persimilis FBgn0155166 I 0.852
GF21877 Drosophila ananassae FBgn0098877 I 0.846
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.846
AGAP000063 Anopheles gambiae AGAP000063 I 0.846
toy Drosophila melanogaster FBgn0019650 D 0.846
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.846
ASIS012967 Anopheles sinensis ASIS012967 I 0.846
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.846
AMIN002127 Anopheles minimus AMIN002127 I 0.846
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.846
AARA001115 Anopheles arabiensis AARA001115 I 0.846
GM13021 Drosophila sechellia FBgn0167952 I 0.846
GE14563 Drosophila yakuba FBgn0232162 I 0.846
GG16402 Drosophila erecta FBgn0108634 I 0.846
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.846
AMEC021831 Anopheles melas AMEC021831 I 0.841
AALB006354 Anopheles albimanus AALB006354 I 0.841
AFUN011575 Anopheles funestus AFUN011575 I 0.841
ISCW021772 Ixodes scapularis ISCW021772 I 0.841
AFAF009619 Anopheles farauti AFAF009619 I 0.836
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.835
AAEL002321 Aedes aegypti AAEL002321 I 0.835
ACUA021227 Anopheles culicifacies ACUA021227 I 0.835
HelroG173449 Helobdella robusta HelroG173449 I 0.835
D918_01592 Trichuris suis D918_01592 I 0.835
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.832
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.830
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.830
ADAC003449 Anopheles darlingi ADAC003449 I 0.830
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.830
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.830
AEPI005803 Anopheles epiroticus AEPI005803 I 0.830
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.826
AFUN011570 Anopheles funestus AFUN011570 I 0.825
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.825
AMIN002132 Anopheles minimus AMIN002132 I 0.825
AATE014626 Anopheles atroparvus AATE014626 I 0.825
ADIR000973 Anopheles dirus ADIR000973 I 0.825
ACHR009845 Anopheles christyi ACHR009845 I 0.825
T265_14971 Opisthorchis viverrini T265_14971 I 0.817
T265_09221 Opisthorchis viverrini T265_09221 I 0.813
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.808
PHUM097050 Pediculus humanus PHUM097050 I 0.808
CRE07226 Caenorhabditis remanei CRE07226 I 0.808
CBN04513 Caenorhabditis brenneri CBN04513 I 0.808
Smp_160670 Schistosoma mansoni Smp_160670 I 0.802
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.802
L892_g3713 Steinernema scapterisci L892_g3713 I 0.802
ISCW006352 Ixodes scapularis ISCW006352 I 0.802
MCINX016249 Melitaea cinxia MCINX016249 I 0.802
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.802
D915_07175 Fasciola hepatica D915_07175 I 0.802
vab-3 Caenorhabditis elegans WBGene00006870 I 0.802
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.797
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.797
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.797
A_05170 Schistosoma haematobium A_05170 I 0.797
csin101119 Clonorchis sinensis csin101119 I 0.796
Smp_170750 Schistosoma mansoni Smp_170750 I 0.791
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.791
ASIS012617 Anopheles sinensis ASIS012617 I 0.790
GD24416 Drosophila simulans FBgn0195753 I 0.786
EFV57892 Trichinella spiralis EFV57892 I 0.780
ACUA016154 Anopheles culicifacies ACUA016154 I 0.780
ACHR008920 Anopheles christyi ACHR008920 I 0.780
AALB006643 Anopheles albimanus AALB006643 I 0.780
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.780
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.780
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.780
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.778
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.775
AGAP000067 Anopheles gambiae AGAP000067 I 0.775
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.775
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.775
AARA001110 Anopheles arabiensis AARA001110 I 0.775
AFAF017899 Anopheles farauti AFAF017899 I 0.775
AMEC013051 Anopheles melas AMEC013051 I 0.775
AMEM002691 Anopheles merus AMEM002691 I 0.775
AEPI005798 Anopheles epiroticus AEPI005798 I 0.775
ADIR000968 Anopheles dirus ADIR000968 I 0.770
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.764
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.764
D917_00854 Trichinella nativa D917_00854 I 0.758
csin110224 Clonorchis sinensis csin110224 I 0.747
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.725
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.709
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.703
ADAC001560 Anopheles darlingi ADAC001560 I 0.703