csin110224 (Clonorchis sinensis)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		csin110224 T237837_2.00 WormBase:ParaSite (2015-Oct-22)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.874 0.874
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.874 0.874
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.874 0.874
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.874 0.874
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.874 0.874
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.874 0.874
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.874 0.874
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.874 0.874
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.874 0.874
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.874 0.874
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.874 0.874
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.874 0.874
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.874 0.874
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.868 0.868
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.868 0.868
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.868 0.868
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.868 0.868
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.868 0.868
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.868 0.868
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.868 0.868
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.868 0.868
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.862 0.862
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.862 0.862
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.862 0.862
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.838 0.838
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.838 0.838
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.838 0.838
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
csin110224 Paired box 98 222
csin110224 Homeodomain 387 428

Links

Other Homeodomain,Paired box family TFs
Other Clonorchis sinensis TFs

178 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
T265_14971 Opisthorchis viverrini T265_14971 I 0.957
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.886
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.886
pax6b Oryzias latipes ENSORLG00000009913 I 0.886
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.886
D915_07175 Fasciola hepatica D915_07175 I 0.886
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.880
pax6.S Xenopus laevis XB-GENE-6464331 I 0.874
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.874
pax6b Danio rerio ENSDARG00000045936 I 0.874
pax6a Danio rerio ENSDARG00000103379 I 0.874
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.874
Smp_170750 Schistosoma mansoni Smp_170750 I 0.874
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.874
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.874
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.868
pax6.L Xenopus laevis XB-GENE-865046 I 0.868
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.868
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.868
PAX6 Homo sapiens ENSG00000007372 D 0.868
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.862
ey Drosophila virilis FBgn0028754 I 0.862
ey Drosophila melanogaster FBgn0005558 D 0.862
EFV57892 Trichinella spiralis EFV57892 I 0.862
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.862
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.862
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.862
L798_00712 Zootermopsis nevadensis L798_00712 I 0.850
A_05170 Schistosoma haematobium A_05170 I 0.846
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.846
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.844
Smp_160670 Schistosoma mansoni Smp_160670 I 0.841
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.838
TC007409 Tribolium castaneum TC007409 I 0.838
GF21877 Drosophila ananassae FBgn0098877 I 0.838
ADAC001560 Anopheles darlingi ADAC001560 I 0.833
T265_09221 Opisthorchis viverrini T265_09221 I 0.824
AAEL002321 Aedes aegypti AAEL002321 I 0.820
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.819
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.813
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.813
csin101119 Clonorchis sinensis csin101119 I 0.809
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.802
PAX6 Procavia capensis ENSPCAG00000005165 I 0.802
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.802
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.802
pax6 Xenopus tropicalis XB-GENE-484088 I 0.802
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.802
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.802
PAX6 Sus scrofa ENSSSCG00000013320 I 0.802
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.802
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.802
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.802
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.802
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.802
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.802
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.802
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.802
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.802
PAX6 Bos taurus ENSBTAG00000004561 I 0.802
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.802
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.802
PAX6 Microcebus murinus ENSMICG00000004089 I 0.802
PAX6 Gallus gallus ENSGALG00000012123 I 0.802
Pax6 Mus musculus ENSMUSG00000027168 D 0.802
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.802
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.802
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.802
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.802
L798_11483 Zootermopsis nevadensis L798_11483 I 0.801
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.797
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.797
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.797
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.797
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.797
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.797
GB50342 Apis mellifera GB50342 I 0.797
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.797
PAX6 Felis catus ENSFCAG00000007094 I 0.797
NV15820 Nasonia vitripennis NV15820 I 0.797
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.797
TC008176 Tribolium castaneum TC008176 I 0.797
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.797
ACUA021227 Anopheles culicifacies ACUA021227 I 0.796
PAX6 Sorex araneus ENSSARG00000011424 I 0.792
GE14559 Drosophila yakuba FBgn0232158 I 0.791
GK13702 Drosophila willistoni FBgn0215710 I 0.791
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.791
ey Drosophila pseudoobscura FBgn0018538 I 0.791
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.791
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.791
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.791
GG16399 Drosophila erecta FBgn0108631 I 0.791
GI14081 Drosophila mojavensis FBgn0136835 I 0.791
ey Drosophila persimilis FBgn0043659 I 0.791
ey Drosophila sechellia FBgn0068720 I 0.791
GF22818 Drosophila ananassae FBgn0099812 I 0.791
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.786
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.786
D918_01592 Trichuris suis D918_01592 I 0.786
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.786
NV17076 Nasonia vitripennis NV17076 I 0.786
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.786
GB41504 Apis mellifera GB41504 I 0.786
ACUA016154 Anopheles culicifacies ACUA016154 I 0.784
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.784
AALB006643 Anopheles albimanus AALB006643 I 0.784
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.784
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.782
SMAR013763 Strigamia maritima SMAR013763 I 0.780
PAX6 Echinops telfairi ENSETEG00000002655 I 0.780
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.780
PHUM097050 Pediculus humanus PHUM097050 I 0.779
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.778
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.775
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.775
LotgiG133720 Lottia gigantea LotgiG133720 I 0.775
GL17563 Drosophila persimilis FBgn0155166 I 0.769
GK13683 Drosophila willistoni FBgn0215691 I 0.769
GI14042 Drosophila mojavensis FBgn0136796 I 0.769
GJ13300 Drosophila virilis FBgn0200526 I 0.769
GM13021 Drosophila sechellia FBgn0167952 I 0.769
GH23963 Drosophila grimshawi FBgn0131420 I 0.769
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.769
GE14563 Drosophila yakuba FBgn0232162 I 0.769
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.769
GG16402 Drosophila erecta FBgn0108634 I 0.769
PAX6 Equus caballus ENSECAG00000021000 I 0.769
toy Drosophila melanogaster FBgn0019650 D 0.769
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.766
AFUN011575 Anopheles funestus AFUN011575 I 0.764
AMIN002127 Anopheles minimus AMIN002127 I 0.764
AGAP000063 Anopheles gambiae AGAP000063 I 0.764
ASIS012967 Anopheles sinensis ASIS012967 I 0.764
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.764
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.764
AMEC021831 Anopheles melas AMEC021831 I 0.764
AALB006354 Anopheles albimanus AALB006354 I 0.764
AARA001115 Anopheles arabiensis AARA001115 I 0.764
AATE014626 Anopheles atroparvus AATE014626 I 0.760
AMIN002132 Anopheles minimus AMIN002132 I 0.760
ISCW006352 Ixodes scapularis ISCW006352 I 0.760
AFUN011570 Anopheles funestus AFUN011570 I 0.760
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.760
HelroG173449 Helobdella robusta HelroG173449 I 0.760
ADIR000973 Anopheles dirus ADIR000973 I 0.760
TsM_000166900 Taenia solium TsM_000166900 I 0.760
ACHR009845 Anopheles christyi ACHR009845 I 0.760
ISCW021772 Ixodes scapularis ISCW021772 I 0.757
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.756
AARA001110 Anopheles arabiensis AARA001110 I 0.756
AMEM002691 Anopheles merus AMEM002691 I 0.756
AGAP000067 Anopheles gambiae AGAP000067 I 0.756
AMEC013051 Anopheles melas AMEC013051 I 0.756
AEPI005798 Anopheles epiroticus AEPI005798 I 0.756
AFAF017899 Anopheles farauti AFAF017899 I 0.756
GD24416 Drosophila simulans FBgn0195753 I 0.754
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.753
ADAC003449 Anopheles darlingi ADAC003449 I 0.749
MCINX016249 Melitaea cinxia MCINX016249 I 0.749
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.749
AFAF009619 Anopheles farauti AFAF009619 I 0.749
HelroG80374 Helobdella robusta HelroG80374 I 0.747
ACHR008920 Anopheles christyi ACHR008920 I 0.747
L892_g3713 Steinernema scapterisci L892_g3713 I 0.742
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.742
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.742
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.736
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.736
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.736
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.736
ASIS012617 Anopheles sinensis ASIS012617 I 0.729
AEPI005803 Anopheles epiroticus AEPI005803 I 0.725
CRE07226 Caenorhabditis remanei CRE07226 I 0.725
vab-3 Caenorhabditis elegans WBGene00006870 I 0.725
CBN04513 Caenorhabditis brenneri CBN04513 I 0.725
D917_00854 Trichinella nativa D917_00854 I 0.715
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.709