ENSCING00000006503 (Ciona intestinalis)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSCING00000006503 T237287_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.912 0.912
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.912 0.912
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.912 0.912
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.912 0.912
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.912 0.912
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.912 0.912
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.912 0.912
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.912 0.912
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.912 0.912
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.912 0.912
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.912 0.912
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.912 0.912
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.907 0.907
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.907 0.907
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.907 0.907
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.907 0.907
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.907 0.907
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.907 0.907
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.907 0.907
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.907 0.907
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.907 0.907
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.874 0.874
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.874 0.874
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.874 0.874
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.863 0.863
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.863 0.863
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.863 0.863
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCINP00000013350 Paired box 26 150
ENSCINP00000013350 Homeodomain 232 288

Links

Other Homeodomain,Paired box family TFs
Other Ciona intestinalis TFs

195 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.989
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.923
pax6b Oryzias latipes ENSORLG00000009913 I 0.923
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.918
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.918
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.918
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.918
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.918
pax6a Danio rerio ENSDARG00000103379 I 0.918
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.918
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.918
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.918
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.918
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.918
PAX6 Felis catus ENSFCAG00000007094 I 0.918
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.918
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.918
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.918
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.918
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.918
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.918
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.918
pax6.S Xenopus laevis XB-GENE-6464331 I 0.918
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.918
PAX6 Microcebus murinus ENSMICG00000004089 I 0.912
PAX6 Sus scrofa ENSSSCG00000013320 I 0.912
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.912
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.912
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.912
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.912
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.912
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.912
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.912
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.912
PAX6 Procavia capensis ENSPCAG00000005165 I 0.912
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.912
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.912
Pax6 Mus musculus ENSMUSG00000027168 D 0.912
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.912
PAX6 Homo sapiens ENSG00000007372 D 0.912
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.912
PAX6 Bos taurus ENSBTAG00000004561 I 0.912
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.912
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.912
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.912
pax6.L Xenopus laevis XB-GENE-865046 I 0.912
pax6 Xenopus tropicalis XB-GENE-484088 I 0.912
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.912
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.912
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.912
pax6b Danio rerio ENSDARG00000045936 I 0.912
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.912
PAX6 Gallus gallus ENSGALG00000012123 I 0.912
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.912
PAX6 Sorex araneus ENSSARG00000011424 I 0.908
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.907
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.907
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.906
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.901
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.898
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.896
PAX6 Echinops telfairi ENSETEG00000002655 I 0.896
PAX6 Equus caballus ENSECAG00000021000 I 0.890
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.890
TC008176 Tribolium castaneum TC008176 I 0.885
SMAR013763 Strigamia maritima SMAR013763 I 0.885
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.885
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.885
L798_00712 Zootermopsis nevadensis L798_00712 I 0.879
GB41504 Apis mellifera GB41504 I 0.879
NV17076 Nasonia vitripennis NV17076 I 0.879
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.879
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.879
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.879
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.879
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.879
TC007409 Tribolium castaneum TC007409 I 0.879
L798_11483 Zootermopsis nevadensis L798_11483 I 0.878
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.874
GB50342 Apis mellifera GB50342 I 0.874
ey Drosophila melanogaster FBgn0005558 D 0.874
NV15820 Nasonia vitripennis NV15820 I 0.874
GL17563 Drosophila persimilis FBgn0155166 I 0.868
GI14081 Drosophila mojavensis FBgn0136835 I 0.868
GI14042 Drosophila mojavensis FBgn0136796 I 0.868
GJ13300 Drosophila virilis FBgn0200526 I 0.868
GK13702 Drosophila willistoni FBgn0215710 I 0.868
GH23963 Drosophila grimshawi FBgn0131420 I 0.868
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.868
GE14559 Drosophila yakuba FBgn0232158 I 0.868
GK13683 Drosophila willistoni FBgn0215691 I 0.868
ey Drosophila persimilis FBgn0043659 I 0.868
ey Drosophila virilis FBgn0028754 I 0.868
ey Drosophila pseudoobscura FBgn0018538 I 0.868
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.868
ey Drosophila sechellia FBgn0068720 I 0.868
GG16399 Drosophila erecta FBgn0108631 I 0.868
GF22818 Drosophila ananassae FBgn0099812 I 0.868
toy Drosophila melanogaster FBgn0019650 D 0.863
GG16402 Drosophila erecta FBgn0108634 I 0.863
D918_01592 Trichuris suis D918_01592 I 0.863
GE14563 Drosophila yakuba FBgn0232162 I 0.863
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.863
LotgiG133720 Lottia gigantea LotgiG133720 I 0.863
GM13021 Drosophila sechellia FBgn0167952 I 0.863
GF21877 Drosophila ananassae FBgn0098877 I 0.863
ISCW021772 Ixodes scapularis ISCW021772 I 0.862
ADAC001560 Anopheles darlingi ADAC001560 I 0.859
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.857
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.857
ADIR000973 Anopheles dirus ADIR000973 I 0.854
AATE014626 Anopheles atroparvus AATE014626 I 0.854
ACHR009845 Anopheles christyi ACHR009845 I 0.854
GD24416 Drosophila simulans FBgn0195753 I 0.854
AFUN011570 Anopheles funestus AFUN011570 I 0.854
AMIN002132 Anopheles minimus AMIN002132 I 0.854
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.854
HelroG80374 Helobdella robusta HelroG80374 I 0.846
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.846
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.846
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.842
CBN04513 Caenorhabditis brenneri CBN04513 I 0.841
AGAP000063 Anopheles gambiae AGAP000063 I 0.841
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.841
CRE07226 Caenorhabditis remanei CRE07226 I 0.841
AMIN002127 Anopheles minimus AMIN002127 I 0.841
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.841
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.841
ASIS012967 Anopheles sinensis ASIS012967 I 0.841
AARA001115 Anopheles arabiensis AARA001115 I 0.841
AFUN011575 Anopheles funestus AFUN011575 I 0.835
AAEL002321 Aedes aegypti AAEL002321 I 0.835
AALB006354 Anopheles albimanus AALB006354 I 0.835
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.835
L892_g3713 Steinernema scapterisci L892_g3713 I 0.835
AMEC021831 Anopheles melas AMEC021831 I 0.835
AFAF009619 Anopheles farauti AFAF009619 I 0.830
PHUM097050 Pediculus humanus PHUM097050 I 0.830
vab-3 Caenorhabditis elegans WBGene00006870 I 0.830
ACHR008920 Anopheles christyi ACHR008920 I 0.829
ADAC003449 Anopheles darlingi ADAC003449 I 0.825
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.819
T265_09221 Opisthorchis viverrini T265_09221 I 0.819
Smp_160670 Schistosoma mansoni Smp_160670 I 0.819
ASIS012617 Anopheles sinensis ASIS012617 I 0.818
T265_14971 Opisthorchis viverrini T265_14971 I 0.817
A_05170 Schistosoma haematobium A_05170 I 0.813
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.813
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.808
EFV57892 Trichinella spiralis EFV57892 I 0.808
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.808
ISCW006352 Ixodes scapularis ISCW006352 I 0.808
AALB006643 Anopheles albimanus AALB006643 I 0.808
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.808
ACUA016154 Anopheles culicifacies ACUA016154 I 0.808
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.808
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.808
ACUA021227 Anopheles culicifacies ACUA021227 I 0.808
csin101119 Clonorchis sinensis csin101119 I 0.803
AMEM002691 Anopheles merus AMEM002691 I 0.802
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.802
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.802
AGAP000067 Anopheles gambiae AGAP000067 I 0.802
AMEC013051 Anopheles melas AMEC013051 I 0.802
Smp_170750 Schistosoma mansoni Smp_170750 I 0.802
AARA001110 Anopheles arabiensis AARA001110 I 0.802
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.802
AFAF017899 Anopheles farauti AFAF017899 I 0.802
AEPI005798 Anopheles epiroticus AEPI005798 I 0.802
AEPI005803 Anopheles epiroticus AEPI005803 I 0.802
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.797
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.797
D915_07175 Fasciola hepatica D915_07175 I 0.786
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.785
D917_00854 Trichinella nativa D917_00854 I 0.785
MCINX016249 Melitaea cinxia MCINX016249 I 0.780
csin110224 Clonorchis sinensis csin110224 I 0.780
HelroG173449 Helobdella robusta HelroG173449 I 0.780
fgenesh2_pg.scaffold_23000118 Branchiostoma floridae fgenesh2_pg.scaffold_23000118 I 0.771
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.769
ADIR000968 Anopheles dirus ADIR000968 I 0.765
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.758
TsM_000166900 Taenia solium TsM_000166900 I 0.747
HmN_000466300 Hymenolepis microstoma HmN_000466300 I 0.742
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.736
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.731
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.731
MESCA003564 Megaselia scalaris MESCA003564 I 0.720
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.718
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.715
Aan_R006618 Calypte anna Aan_R006618 I 0.703
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.703
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.703
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.703
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.703