AGAP000067 (Anopheles gambiae)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		AGAP000067 T237226_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.901 0.901
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.901 0.901
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.901 0.901
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.895 0.895
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.895 0.895
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.895 0.895
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.895 0.895
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.895 0.895
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.895 0.895
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.895 0.895
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.895 0.895
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.895 0.895
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.895 0.895
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.895 0.895
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.895 0.895
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.895 0.895
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.890 0.890
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.890 0.890
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.890 0.890
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.890 0.890
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.890 0.890
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.890 0.890
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.890 0.890
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.890 0.890
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.878 0.878
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.878 0.878
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.878 0.878
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AGAP000067-PA Paired box 20 144
AGAP000067-PA Homeodomain 238 284

Links

Other Homeodomain,Paired box family TFs
Other Anopheles gambiae TFs

216 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AMEC013051 Anopheles melas AMEC013051 I 1.000
AMEM002691 Anopheles merus AMEM002691 I 1.000
AMIN002132 Anopheles minimus AMIN002132 I 1.000
ACHR009845 Anopheles christyi ACHR009845 I 1.000
AFUN011570 Anopheles funestus AFUN011570 I 1.000
ADIR000973 Anopheles dirus ADIR000973 I 1.000
AFAF017899 Anopheles farauti AFAF017899 I 1.000
AEPI005798 Anopheles epiroticus AEPI005798 I 1.000
AQUA008313 Anopheles quadriannulatus AQUA008313 I 1.000
AARA001110 Anopheles arabiensis AARA001110 I 1.000
AATE014626 Anopheles atroparvus AATE014626 I 1.000
ASTEI06205 Anopheles stephensi ASTEI06205 I 1.000
AALB006643 Anopheles albimanus AALB006643 I 0.994
ACUA016154 Anopheles culicifacies ACUA016154 I 0.994
ADAC001560 Anopheles darlingi ADAC001560 I 0.987
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.965
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.965
ASIS012617 Anopheles sinensis ASIS012617 I 0.945
TC007409 Tribolium castaneum TC007409 I 0.924
L798_00712 Zootermopsis nevadensis L798_00712 I 0.919
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.907
GD24416 Drosophila simulans FBgn0195753 I 0.906
GF21877 Drosophila ananassae FBgn0098877 I 0.901
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.900
pax6a Danio rerio ENSDARG00000103379 I 0.895
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.895
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.895
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.895
pax6b Oryzias latipes ENSORLG00000009913 I 0.895
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.892
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.890
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.890
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.890
PAX6 Homo sapiens ENSG00000007372 D 0.890
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.890
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.890
pax6b Danio rerio ENSDARG00000045936 I 0.890
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.890
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.890
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.884
pax6.L Xenopus laevis XB-GENE-865046 I 0.884
pax6.S Xenopus laevis XB-GENE-6464331 I 0.884
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.884
ISCW006352 Ixodes scapularis ISCW006352 I 0.878
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.878
ey Drosophila melanogaster FBgn0005558 D 0.878
SMAR013763 Strigamia maritima SMAR013763 I 0.874
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.872
ey Drosophila virilis FBgn0028754 I 0.872
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.868
PHUM097050 Pediculus humanus PHUM097050 I 0.866
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.866
GL17563 Drosophila persimilis FBgn0155166 I 0.863
GI14042 Drosophila mojavensis FBgn0136796 I 0.863
GK13683 Drosophila willistoni FBgn0215691 I 0.863
GH23963 Drosophila grimshawi FBgn0131420 I 0.863
GJ13300 Drosophila virilis FBgn0200526 I 0.863
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.863
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.860
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.860
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.857
GB41504 Apis mellifera GB41504 I 0.857
NV17076 Nasonia vitripennis NV17076 I 0.857
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.857
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.852
toy Drosophila melanogaster FBgn0019650 D 0.852
GE14563 Drosophila yakuba FBgn0232162 I 0.852
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.852
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.852
GM13021 Drosophila sechellia FBgn0167952 I 0.852
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.852
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.852
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.852
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.852
PAX6 Felis catus ENSFCAG00000007094 I 0.852
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.852
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.852
GG16402 Drosophila erecta FBgn0108634 I 0.852
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.852
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.852
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.852
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.846
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.846
PAX6 Sus scrofa ENSSSCG00000013320 I 0.846
pax6 Xenopus tropicalis XB-GENE-484088 I 0.846
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.846
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.846
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.846
PAX6 Bos taurus ENSBTAG00000004561 I 0.846
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.846
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.846
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.846
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.846
PAX6 Microcebus murinus ENSMICG00000004089 I 0.846
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.846
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.846
PAX6 Procavia capensis ENSPCAG00000005165 I 0.846
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.846
Pax6 Mus musculus ENSMUSG00000027168 D 0.846
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.846
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.846
PAX6 Gallus gallus ENSGALG00000012123 I 0.846
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.841
L798_11483 Zootermopsis nevadensis L798_11483 I 0.840
PAX6 Sorex araneus ENSSARG00000011424 I 0.838
TC008176 Tribolium castaneum TC008176 I 0.835
GF22818 Drosophila ananassae FBgn0099812 I 0.835
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.835
NV15820 Nasonia vitripennis NV15820 I 0.835
GB50342 Apis mellifera GB50342 I 0.835
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.835
GI14081 Drosophila mojavensis FBgn0136835 I 0.830
GK13702 Drosophila willistoni FBgn0215710 I 0.830
ey Drosophila pseudoobscura FBgn0018538 I 0.830
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.830
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.830
ey Drosophila persimilis FBgn0043659 I 0.830
PAX6 Echinops telfairi ENSETEG00000002655 I 0.827
GE14559 Drosophila yakuba FBgn0232158 I 0.824
GG16399 Drosophila erecta FBgn0108631 I 0.824
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.824
PAX6 Equus caballus ENSECAG00000021000 I 0.824
ey Drosophila sechellia FBgn0068720 I 0.824
ADAC003449 Anopheles darlingi ADAC003449 I 0.819
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.819
D918_01592 Trichuris suis D918_01592 I 0.819
csin101119 Clonorchis sinensis csin101119 I 0.815
AAEL002321 Aedes aegypti AAEL002321 I 0.814
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.813
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.813
AFAF009619 Anopheles farauti AFAF009619 I 0.813
ISCW021772 Ixodes scapularis ISCW021772 I 0.812
ACHR008920 Anopheles christyi ACHR008920 I 0.812
MCINX016249 Melitaea cinxia MCINX016249 I 0.808
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.808
LotgiG133720 Lottia gigantea LotgiG133720 I 0.808
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.802
D917_00854 Trichinella nativa D917_00854 I 0.801
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.797
EFV57892 Trichinella spiralis EFV57892 I 0.791
D915_07175 Fasciola hepatica D915_07175 I 0.791
Smp_170750 Schistosoma mansoni Smp_170750 I 0.785
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.785
A_05170 Schistosoma haematobium A_05170 I 0.775
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.775
HelroG80374 Helobdella robusta HelroG80374 I 0.775
Smp_160670 Schistosoma mansoni Smp_160670 I 0.775
ACUA021227 Anopheles culicifacies ACUA021227 I 0.773
T265_09221 Opisthorchis viverrini T265_09221 I 0.769
CBN04513 Caenorhabditis brenneri CBN04513 I 0.769
AALB006354 Anopheles albimanus AALB006354 I 0.769
CRE07226 Caenorhabditis remanei CRE07226 I 0.769
AGAP000063 Anopheles gambiae AGAP000063 I 0.764
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.764
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.764
ASIS012967 Anopheles sinensis ASIS012967 I 0.764
L892_g3713 Steinernema scapterisci L892_g3713 I 0.764
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.764
AARA001115 Anopheles arabiensis AARA001115 I 0.764
AMIN002127 Anopheles minimus AMIN002127 I 0.764
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.762
HelroG173449 Helobdella robusta HelroG173449 I 0.762
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.762
AMEC021831 Anopheles melas AMEC021831 I 0.758
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.758
AFUN011575 Anopheles funestus AFUN011575 I 0.758
csin110224 Clonorchis sinensis csin110224 I 0.756
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.753
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.753
ADIR000968 Anopheles dirus ADIR000968 I 0.749
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.747
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.747
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.747
vab-3 Caenorhabditis elegans WBGene00006870 I 0.747
TsM_000166900 Taenia solium TsM_000166900 I 0.744
T265_14971 Opisthorchis viverrini T265_14971 I 0.744
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.744
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.743
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.741
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.731
AEPI005803 Anopheles epiroticus AEPI005803 I 0.725
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.725
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.721
MESCA003564 Megaselia scalaris MESCA003564 I 0.714
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.710
PAX2 Cavia porcellus ENSCPOG00000000939 I 0.705
PAX2 Oryctolagus cuniculus ENSOCUG00000012860 I 0.705
PAX2 Otolemur garnettii ENSOGAG00000015274 I 0.705
Pax2 Mus musculus ENSMUSG00000004231 D 0.705
PAX2 Monodelphis domestica ENSMODG00000019353 I 0.705
PAX2 Microcebus murinus ENSMICG00000001357 I 0.705
PAX2 Macaca mulatta ENSMMUG00000009163 I 0.705
PAX2 Ochotona princeps ENSOPRG00000007096 I 0.705
ENSPANG00000021132 Papio anubis ENSPANG00000021132 I 0.705
ENSSHAG00000014328 Sarcophilus harrisii ENSSHAG00000014328 I 0.705
PAX2 Sus scrofa ENSSSCG00000010556 I 0.705
PAX2 Pteropus vampyrus ENSPVAG00000002148 I 0.705
PAX2 Pan troglodytes ENSPTRG00000002853 I 0.705
PAX2 Procavia capensis ENSPCAG00000006623 I 0.705
ENSPPYG00000002572 Pongo abelii ENSPPYG00000002572 I 0.705
ENSMEUG00000013247 Macropus eugenii ENSMEUG00000013247 I 0.705
PAX2 Loxodonta africana ENSLAFG00000002388 I 0.705
PAX2 Equus caballus ENSECAG00000021123 I 0.705
PAX2 Erinaceus europaeus ENSEEUG00000001995 I 0.705
PAX2 Dasypus novemcinctus ENSDNOG00000013328 I 0.705
PAX2 Callithrix jacchus ENSCJAG00000017397 I 0.705
PAX2 Bos taurus ENSBTAG00000021566 I 0.705
PAX2 Canis familiaris ENSCAFG00000009709 I 0.705
PAX2 Tursiops truncatus ENSTTRG00000015106 I 0.705
PAX2 Felis catus ENSFCAG00000011602 I 0.705
ENSP00000359319 Macaca fascicularis ENSP00000359319 I 0.705
ENSP00000359319-D1 Bos grunniens ENSP00000359319-D1 I 0.705
PAX2 Gorilla gorilla ENSGGOG00000014908 I 0.705
PAX2 Homo sapiens ENSG00000075891 D 0.705
Myotis_brandtii_PAX2_10025650 Myotis brandtii Myotis_brandtii_PAX2_10025650 I 0.705
ENSAMEG00000017523 Ailuropoda melanoleuca ENSAMEG00000017523 I 0.705