ENSPPYG00000003386 (Pongo abelii)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		ENSPPYG00000003386 T237465_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.994 0.994
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.994 0.994
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.994 0.994
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.994 0.994
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.994 0.994
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.994 0.994
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.994 0.994
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.994 0.994
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.994 0.994
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.994 0.994
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.994 0.994
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.994 0.994
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.994 0.994
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.988 0.988
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.988 0.988
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.988 0.988
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.988 0.988
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.988 0.988
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.988 0.988
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.988 0.988
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.988 0.988
ey
M03896_2.00 		Drosophila melanogaster
CKAATTAD
HTAATTMG		 SELEX
Nitta et al.(2015)
ey_1 		0.922 0.922
ey
M03897_2.00 		Drosophila melanogaster
HTAATCKMATTAD
HTAATKMGATTAD		 SELEX
Nitta et al.(2015)
ey_2 		0.922 0.922
ey
M03898_2.00 		Drosophila melanogaster
WAAYYRRTTN
NAAYYRRTTW		 SELEX
Nitta et al.(2015)
ey_3 		0.922 0.922
toy
M03899_2.00 		Drosophila melanogaster
TTYACGCWTGASTGMACAN
NTGTKCASTCAWGCGTRAA		 SELEX
Nitta et al.(2015)
toy_1 		0.892 0.892
toy
M03900_2.00 		Drosophila melanogaster
NTYACGCWTSAVTGMRCNN
NNGYKCABTSAWGCGTRAN		 SELEX
Nitta et al.(2015)
toy_2 		0.892 0.892
toy
M03901_2.00 		Drosophila melanogaster
VATTANBHAYGSWYSRN
NYSRWSCRTDVNTAATB		 SELEX
Nitta et al.(2015)
toy_3 		0.892 0.892
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSPPYP00000003888 Paired box 4 142
ENSPPYP00000003888 Homeodomain 225 266

Links

Other Homeodomain,Paired box family TFs
Other Pongo abelii TFs

224 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
PAX6 Homo sapiens ENSG00000007372 D 0.994
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.994
PAX6 Gallus gallus ENSGALG00000012123 I 0.994
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.994
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.994
PAX6 Sus scrofa ENSSSCG00000013320 I 0.994
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.994
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.994
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.994
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.994
PAX6 Procavia capensis ENSPCAG00000005165 I 0.994
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.994
Pax6 Mus musculus ENSMUSG00000027168 D 0.994
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.994
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.994
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.994
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.994
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.994
PAX6 Microcebus murinus ENSMICG00000004089 I 0.994
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.994
PAX6 Bos taurus ENSBTAG00000004561 I 0.994
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.994
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.994
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.994
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.994
pax6 Xenopus tropicalis XB-GENE-484088 I 0.994
PAX6 Felis catus ENSFCAG00000007094 I 0.988
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.988
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.988
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.988
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.988
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.988
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.988
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.988
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.988
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.988
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.988
pax6b Danio rerio ENSDARG00000045936 I 0.988
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.988
pax6a Danio rerio ENSDARG00000103379 I 0.988
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.988
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.988
pax6b Oryzias latipes ENSORLG00000009913 I 0.982
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.982
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.982
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.982
pax6.L Xenopus laevis XB-GENE-865046 I 0.982
pax6.S Xenopus laevis XB-GENE-6464331 I 0.976
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.976
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.976
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.976
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.970
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.964
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.964
PAX6 Equus caballus ENSECAG00000021000 I 0.958
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.958
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.958
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.946
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.934
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.934
GI14081 Drosophila mojavensis FBgn0136835 I 0.928
ey Drosophila pseudoobscura FBgn0018538 I 0.928
ey Drosophila persimilis FBgn0043659 I 0.928
TC008176 Tribolium castaneum TC008176 I 0.928
GK13702 Drosophila willistoni FBgn0215710 I 0.928
SMAR013763 Strigamia maritima SMAR013763 I 0.928
GG16399 Drosophila erecta FBgn0108631 I 0.922
NV15820 Nasonia vitripennis NV15820 I 0.922
ey Drosophila melanogaster FBgn0005558 D 0.922
GB50342 Apis mellifera GB50342 I 0.922
ey Drosophila sechellia FBgn0068720 I 0.922
GE14559 Drosophila yakuba FBgn0232158 I 0.922
ey Drosophila virilis FBgn0028754 I 0.922
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.922
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.916
L798_00712 Zootermopsis nevadensis L798_00712 I 0.916
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.910
PAX6 Sorex araneus ENSSARG00000011424 I 0.908
TC007409 Tribolium castaneum TC007409 I 0.904
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.898
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.898
ISCW021772 Ixodes scapularis ISCW021772 I 0.898
PAX6 Echinops telfairi ENSETEG00000002655 I 0.896
ACUA016154 Anopheles culicifacies ACUA016154 I 0.892
ACHR009845 Anopheles christyi ACHR009845 I 0.892
toy Drosophila melanogaster FBgn0019650 D 0.892
AEPI005798 Anopheles epiroticus AEPI005798 I 0.892
AFAF017899 Anopheles farauti AFAF017899 I 0.892
AATE014626 Anopheles atroparvus AATE014626 I 0.892
ADIR000973 Anopheles dirus ADIR000973 I 0.892
AARA001110 Anopheles arabiensis AARA001110 I 0.892
GE14563 Drosophila yakuba FBgn0232162 I 0.892
ISCW006352 Ixodes scapularis ISCW006352 I 0.892
AGAP000067 Anopheles gambiae AGAP000067 I 0.892
AALB006643 Anopheles albimanus AALB006643 I 0.892
GD24416 Drosophila simulans FBgn0195753 I 0.892
AFUN011570 Anopheles funestus AFUN011570 I 0.892
GM13021 Drosophila sechellia FBgn0167952 I 0.892
GG16402 Drosophila erecta FBgn0108634 I 0.892
GF21877 Drosophila ananassae FBgn0098877 I 0.892
AMIN002132 Anopheles minimus AMIN002132 I 0.892
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.892
ASIS012617 Anopheles sinensis ASIS012617 I 0.892
AMEM002691 Anopheles merus AMEM002691 I 0.892
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.892
AMEC013051 Anopheles melas AMEC013051 I 0.892
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.890
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.886
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.886
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.886
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.886
HelroG80374 Helobdella robusta HelroG80374 I 0.880
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.874
PHUM097050 Pediculus humanus PHUM097050 I 0.868
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.868
L798_11483 Zootermopsis nevadensis L798_11483 I 0.867
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.862
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.862
GF22818 Drosophila ananassae FBgn0099812 I 0.852
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.850
AFUN011575 Anopheles funestus AFUN011575 I 0.844
L892_g3713 Steinernema scapterisci L892_g3713 I 0.844
AMEC021831 Anopheles melas AMEC021831 I 0.844
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.844
ACHR008920 Anopheles christyi ACHR008920 I 0.844
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.841
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.838
AAEL002321 Aedes aegypti AAEL002321 I 0.832
CBN04513 Caenorhabditis brenneri CBN04513 I 0.832
CRE07226 Caenorhabditis remanei CRE07226 I 0.832
NV17076 Nasonia vitripennis NV17076 I 0.830
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.830
ADAC003449 Anopheles darlingi ADAC003449 I 0.830
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.830
GB41504 Apis mellifera GB41504 I 0.830
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.826
A_05170 Schistosoma haematobium A_05170 I 0.826
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.826
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.826
Smp_160670 Schistosoma mansoni Smp_160670 I 0.826
AFAF009619 Anopheles farauti AFAF009619 I 0.825
GJ13300 Drosophila virilis FBgn0200526 I 0.824
GK13683 Drosophila willistoni FBgn0215691 I 0.824
GL17563 Drosophila persimilis FBgn0155166 I 0.824
LotgiG133720 Lottia gigantea LotgiG133720 I 0.824
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.824
GH23963 Drosophila grimshawi FBgn0131420 I 0.824
GI14042 Drosophila mojavensis FBgn0136796 I 0.824
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.820
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.820
vab-3 Caenorhabditis elegans WBGene00006870 I 0.814
ADAC001560 Anopheles darlingi ADAC001560 I 0.808
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.808
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.808
Smp_170750 Schistosoma mansoni Smp_170750 I 0.808
EFV57892 Trichinella spiralis EFV57892 I 0.808
ACUA021227 Anopheles culicifacies ACUA021227 I 0.808
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.808
D918_01592 Trichuris suis D918_01592 I 0.808
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.804
AEPI005803 Anopheles epiroticus AEPI005803 I 0.802
D915_07175 Fasciola hepatica D915_07175 I 0.796
D917_00854 Trichinella nativa D917_00854 I 0.790
csin101119 Clonorchis sinensis csin101119 I 0.790
PAX6 Tursiops truncatus ENSTTRG00000002399 I 0.790
MCINX016249 Melitaea cinxia MCINX016249 I 0.790
AALB006354 Anopheles albimanus AALB006354 I 0.780
csin110224 Clonorchis sinensis csin110224 I 0.778
AARA001115 Anopheles arabiensis AARA001115 I 0.775
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.775
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.775
ASIS012967 Anopheles sinensis ASIS012967 I 0.775
AMIN002127 Anopheles minimus AMIN002127 I 0.775
AGAP000063 Anopheles gambiae AGAP000063 I 0.775
HelroG173449 Helobdella robusta HelroG173449 I 0.772
ADIR000968 Anopheles dirus ADIR000968 I 0.770
T265_09221 Opisthorchis viverrini T265_09221 I 0.764
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.753
TsM_000166900 Taenia solium TsM_000166900 I 0.743
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.737
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.731
Aan_R006618 Calypte anna Aan_R006618 I 0.731
ENSFALG00000010839 Ficedula albicollis ENSFALG00000010839 I 0.731
ENSAPLG00000004928 Anas platyrhynchos ENSAPLG00000004928 I 0.731
TTAC_0000231001 Hydatigera taeniaeformis TTAC_0000231001 I 0.731
Gfo_R001537 Geospiza fortis Gfo_R001537 I 0.731
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.725
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.720
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.719
T265_14971 Opisthorchis viverrini T265_14971 I 0.719
ENSP00000359319 Macaca fascicularis ENSP00000359319 I 0.718
ENSP00000359319-D1 Bos grunniens ENSP00000359319-D1 I 0.718
ENSPPYG00000002572 Pongo abelii ENSPPYG00000002572 I 0.718
ENSPANG00000021132 Papio anubis ENSPANG00000021132 I 0.718
ENSMEUG00000013247 Macropus eugenii ENSMEUG00000013247 I 0.718
PAX2 Microcebus murinus ENSMICG00000001357 I 0.718
PAX2 Loxodonta africana ENSLAFG00000002388 I 0.718
PAX2 Procavia capensis ENSPCAG00000006623 I 0.718
PAX2 Pan troglodytes ENSPTRG00000002853 I 0.718
PAX2 Gorilla gorilla ENSGGOG00000014908 I 0.718
PAX2 Pteropus vampyrus ENSPVAG00000002148 I 0.718
PAX2 Oryctolagus cuniculus ENSOCUG00000012860 I 0.718
PAX2 Felis catus ENSFCAG00000011602 I 0.718
Myotis_brandtii_PAX2_10025650 Myotis brandtii Myotis_brandtii_PAX2_10025650 I 0.718
ENSAMEG00000017523 Ailuropoda melanoleuca ENSAMEG00000017523 I 0.718
PAX2 Bos taurus ENSBTAG00000021566 I 0.718
PAX2 Canis familiaris ENSCAFG00000009709 I 0.718
PAX2 Monodelphis domestica ENSMODG00000019353 I 0.718
Pax2 Mus musculus ENSMUSG00000004231 D 0.718
CAA71206 Xenopus laevis CAA71206 I 0.718
PAX2 Otolemur garnettii ENSOGAG00000015274 I 0.718
pax2.L Xenopus laevis XB-GENE-486805 I 0.718
PAX2 Homo sapiens ENSG00000075891 D 0.718
PAX2 Callithrix jacchus ENSCJAG00000017397 I 0.718
PAX2 Erinaceus europaeus ENSEEUG00000001995 I 0.718
PAX2 Sus scrofa ENSSSCG00000010556 I 0.718
ENSSHAG00000014328 Sarcophilus harrisii ENSSHAG00000014328 I 0.718
PAX2 Macaca mulatta ENSMMUG00000009163 I 0.718
PAX2 Equus caballus ENSECAG00000021123 I 0.718
PAX2 Dasypus novemcinctus ENSDNOG00000013328 I 0.718
PAX2 Tursiops truncatus ENSTTRG00000015106 I 0.718
PAX2 Ochotona princeps ENSOPRG00000007096 I 0.718
PAX2 Cavia porcellus ENSCPOG00000000939 I 0.718
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.707