CAA71206 (Xenopus laevis)
Homeodomain,Paired box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00046 (Homeobox)
PF00292 (PAX) 		IPR001356
IPR001523 		CAA71206 T237739_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PAX2
M03294_2.00 		Homo sapiens
SGTCACGCWTSRNTGVNY
RNBCANYSAWGCGTGACS		 SELEX
Jolma et al.(2013)
PAX2_1 		0.974 0.974
PAX2
M05428_2.00 		Homo sapiens
NSGYYACGCNYSRNYRVNBN
NVNBYRNYSRNGCGTRRCSN		 SELEX
Yin et al.(2017)
PAX2_eDBD_HT-SELEX 		0.974 0.974
PAX2
M10808_2.00 		Homo sapiens
NNHNRTYAHKBRHDMBBNN
NNVVKHDYVMDWRAYNDNN		 Transfac
Matys et al.(2006)
V$PAX2_01 		0.974 0.974
PAX2
M10809_2.00 		Homo sapiens
NDSTTTNNN
NNNAAASHN		 Transfac
Matys et al.(2006)
V$PAX2_02 		0.974 0.974
PAX2
M10810_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX2_Q2 		0.974 0.974
PAX2
M05429_2.00 		Homo sapiens
NSGTCACGCWTSANYGVNYN
NRNBCRNTSAWGCGTGACSN		 SELEX
Yin et al.(2017)
PAX2_eDBD_Methyl-HT-SELEX 		0.974 0.974
Pax2
M02690_2.00 		Mus musculus
NRTCAYKB
VMRTGAYN		 SELEX
Mathelier et al.(2014)
MA0067.1 		0.968 0.968
PAX6
M00342_2.00 		Homo sapiens
NNNRCDMATTANNN
NNNTAATKHGYNNN		 PBM
Barrera et al.(2016)
PAX6_REF 		0.718 0.718
Pax6
M00540_2.00 		Mus musculus
CBAATTAA
TTAATTVG		 PBM
Berger et al.(2008)
Pax6_3838 		0.718 0.718
PAX6
M03291_2.00 		Homo sapiens
DTWYACGCWTGANTGMDYH
DRHKCANTCAWGCGTRWAH		 SELEX
Jolma et al.(2013)
PAX6_1 		0.718 0.718
PAX6
M05412_2.00 		Homo sapiens
NYACGCHYSRNYRMNYN
NRNKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_eDBD_HT-SELEX 		0.718 0.718
PAX6
M05414_2.00 		Homo sapiens
NYRCGCNYSRNYRVNYN
NRNBYRNYSRNGCGYRN		 SELEX
Yin et al.(2017)
PAX6_FL_HT-SELEX 		0.718 0.718
PAX6
M02689_2.00 		Homo sapiens
TTYACGCWTSANTK
MANTSAWGCGTRAA		 SELEX
Mathelier et al.(2014)
MA0069.1 		0.718 0.718
PAX6
M09216_2.00 		Homo sapiens
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_HUMAN.H11MO.0.C 		0.718 0.718
Pax6
M09217_2.00 		Mus musculus
TYMYRCWTSRNT
ANYSAWGYRKRA		 Misc
Kulakovskiy et al.(2013)
PAX6_MOUSE.H11MO.0.C 		0.718 0.718
PAX6
M10806_2.00 		Homo sapiens
NHNNTTYACGCWTSANTKVHH
DDBMANTSAWGCGTRAANNDN		 Transfac
Matys et al.(2006)
V$PAX6_01 		0.718 0.718
PAX6
M10807_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PAX6_Q2 		0.718 0.718
PAX6
M00336_2.00 		Homo sapiens
RTGCACAC
GTGTGCAY		 PBM
Barrera et al.(2016)
PAX6_F258S 		0.718 0.718
PAX6
M00340_2.00 		Homo sapiens
NNNNNRN
NYNNNNN		 PBM
Barrera et al.(2016)
PAX6_R242T 		0.718 0.718
PAX6
M00344_2.00 		Homo sapiens
NNMSASGBYNNN
NNNRVCSTSKNN		 PBM
Barrera et al.(2016)
PAX6_V126D 		0.718 0.718
PAX6
M05413_2.00 		Homo sapiens
DYRCGCWTSRNYRMNYN
NRNKYRNYSAWGCGYRH		 SELEX
Yin et al.(2017)
PAX6_eDBD_Methyl-HT-SELEX 		0.718 0.718
PAX6
M05415_2.00 		Homo sapiens
NYACGCHYSRNYRMHYN
NRDKYRNYSRDGCGTRN		 SELEX
Yin et al.(2017)
PAX6_FL_Methyl-HT-SELEX 		0.718 0.718
PAX6
M00335_2.00 		Homo sapiens
BRNNNNNN
NNNNNNYV		 PBM
Barrera et al.(2016)
PAX6_A79E 		0.712 0.712
PAX6
M00337_2.00 		Homo sapiens
NMTAATTANNN
NNNTAATTAKN		 PBM
Barrera et al.(2016)
PAX6_P118R 		0.712 0.712
PAX6
M00338_2.00 		Homo sapiens
WSGVRVDR
YHBYBCSW		 PBM
Barrera et al.(2016)
PAX6_P68S 		0.712 0.712
PAX6
M00339_2.00 		Homo sapiens
NNNNSGKVGGHNN
NNDCCBMCSNNNN		 PBM
Barrera et al.(2016)
PAX6_R128C 		0.712 0.712
PAX6
M00341_2.00 		Homo sapiens
BTSCCCSGSC
GSCSGGGSAV		 PBM
Barrera et al.(2016)
PAX6_R26G 		0.712 0.712
PAX6
M00343_2.00 		Homo sapiens
NNNNCCCVKCNBN
NVNGMBGGGNNNN		 PBM
Barrera et al.(2016)
PAX6_S119R 		0.712 0.712
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
CAA71206 Paired box 16 140
CAA71206 Homeodomain 227 257

Links

Other Homeodomain,Paired box family TFs
Other Xenopus laevis TFs

115 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
pax2.L Xenopus laevis XB-GENE-486805 I 0.994
PAX2 Monodelphis domestica ENSMODG00000019353 I 0.974
Pax2 Mus musculus ENSMUSG00000004231 D 0.974
PAX2 Ochotona princeps ENSOPRG00000007096 I 0.974
PAX2 Macaca mulatta ENSMMUG00000009163 I 0.974
PAX2 Otolemur garnettii ENSOGAG00000015274 I 0.974
ENSMEUG00000013247 Macropus eugenii ENSMEUG00000013247 I 0.974
PAX2 Homo sapiens ENSG00000075891 D 0.974
PAX2 Gorilla gorilla ENSGGOG00000014908 I 0.974
PAX2 Loxodonta africana ENSLAFG00000002388 I 0.974
ENSPANG00000021132 Papio anubis ENSPANG00000021132 I 0.974
PAX2 Microcebus murinus ENSMICG00000001357 I 0.974
PAX2 Procavia capensis ENSPCAG00000006623 I 0.974
PAX2 Tursiops truncatus ENSTTRG00000015106 I 0.974
ENSP00000359319-D1 Bos grunniens ENSP00000359319-D1 I 0.974
ENSP00000359319 Macaca fascicularis ENSP00000359319 I 0.974
Myotis_brandtii_PAX2_10025650 Myotis brandtii Myotis_brandtii_PAX2_10025650 I 0.974
PAX2 Sus scrofa ENSSSCG00000010556 I 0.974
ENSSHAG00000014328 Sarcophilus harrisii ENSSHAG00000014328 I 0.974
ENSPPYG00000002572 Pongo abelii ENSPPYG00000002572 I 0.974
PAX2 Pan troglodytes ENSPTRG00000002853 I 0.974
PAX2 Pteropus vampyrus ENSPVAG00000002148 I 0.974
PAX2 Felis catus ENSFCAG00000011602 I 0.974
PAX2 Oryctolagus cuniculus ENSOCUG00000012860 I 0.974
PAX2 Callithrix jacchus ENSCJAG00000017397 I 0.974
PAX2 Dasypus novemcinctus ENSDNOG00000013328 I 0.974
PAX2 Canis familiaris ENSCAFG00000009709 I 0.974
PAX2 Bos taurus ENSBTAG00000021566 I 0.974
ENSAMEG00000017523 Ailuropoda melanoleuca ENSAMEG00000017523 I 0.974
PAX2 Equus caballus ENSECAG00000021123 I 0.974
PAX2 Cavia porcellus ENSCPOG00000000939 I 0.974
PAX2 Erinaceus europaeus ENSEEUG00000001995 I 0.974
ENSMPUG00000016955 Mustela putorius furo ENSMPUG00000016955 I 0.968
Gfo_R002455 Geospiza fortis Gfo_R002455 I 0.968
Pax2 Rattus norvegicus ENSRNOG00000014253 I 0.968
PAX2 Taeniopygia guttata ENSTGUG00000007620 I 0.968
ENSFALG00000007308 Ficedula albicollis ENSFALG00000007308 I 0.962
PAX2 Echinops telfairi ENSETEG00000014765 I 0.962
ENSLACG00000017470 Latimeria chalumnae ENSLACG00000017470 I 0.962
CAA04222 Xenopus laevis CAA04222 I 0.962
PAX2 Myotis lucifugus ENSMLUG00000015106 I 0.955
ENSSTOG00000011575 Ictidomys tridecemlineatus ENSSTOG00000011575 I 0.952
ENSCSAG00000005568 Chlorocebus sabaeus ENSCSAG00000005568 I 0.952
Pvit_13858 Pogona vitticeps Pvit_13858 I 0.942
Pax2 Dipodomys ordii ENSDORG00000006193 I 0.942
ENSLOCG00000012825 Lepisosteus oculatus ENSLOCG00000012825 I 0.904
ENSAPLG00000014579 Anas platyrhynchos ENSAPLG00000014579 I 0.859
fgenesh2_kg.scaffold_131000004 Branchiostoma floridae fgenesh2_kg.scaffold_131000004 I 0.833
Sakowv30045649m.g Saccoglossus kowalevskii Sakowv30045649m.g I 0.808
NEMVEDRAFT_v1g239535 Nematostella vectensis NEMVEDRAFT_v1g239535 I 0.795
pax6b Oryzias latipes ENSORLG00000009913 I 0.731
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.731
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.731
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.724
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.724
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.724
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.724
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.724
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.724
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.724
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.724
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.724
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.724
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.724
pax6a Danio rerio ENSDARG00000103379 I 0.724
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.724
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.724
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.724
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.724
PAX6 Felis catus ENSFCAG00000007094 I 0.724
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.724
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.724
XP_002159617.1 Hydra magnipapillata XP_002159617.1 N 0.718
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.718
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.718
pax6.S Xenopus laevis XB-GENE-6464331 I 0.718
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.718
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.718
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.718
NEMVEDRAFT_v1g168908 Nematostella vectensis NEMVEDRAFT_v1g168908 I 0.718
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.718
pax6 Xenopus tropicalis XB-GENE-484088 I 0.718
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.718
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.718
pax6b Danio rerio ENSDARG00000045936 I 0.718
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.718
Pax6 Mus musculus ENSMUSG00000027168 D 0.718
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.718
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.718
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.718
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.718
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.718
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.718
PAX6 Microcebus murinus ENSMICG00000004089 I 0.718
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.718
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.718
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.718
PAX6 Homo sapiens ENSG00000007372 D 0.718
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.718
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.718
PAX6 Bos taurus ENSBTAG00000004561 I 0.718
PAX6 Sus scrofa ENSSSCG00000013320 I 0.718
PAX6 Gallus gallus ENSGALG00000012123 I 0.718
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.718
PAX6 Procavia capensis ENSPCAG00000005165 I 0.718
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.718
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.718
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.718
pax6.L Xenopus laevis XB-GENE-865046 I 0.712
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.712
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.705
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.705
ENSOARG00000015552 Ovis aries ENSOARG00000015552 I 0.705
SMAR013763 Strigamia maritima SMAR013763 I 0.705
PAX6 Equus caballus ENSECAG00000021000 I 0.705